Atypical lymphocytosis in leptospirosis: A cohort of hospitalized cases between 1996 and 2009 in State of Rio de Janeiro, Brazil;Linfócitos atípicos na leptospirose: Coorte de pacientes hospitalizados entre 1996 e 2009, Estado do Rio de Janeiro

Revista da Sociedade Brasileira de Medicina Tropical

Volumn 44, Issue 5, 2011, Pages 611-615

  Damasco, Paulo Vieira ^a   Ávila, Carlos André Lins ^a   Barbosa, Angélica Tápia ^a   Ribeiro Carvalho, Marilza de Moura ^a   Pereira, Geraldo Moura Batista ^a,b   de Lemos, Elba Regina Sampaio ^b   Bóia, Márcio Neves ^a   Pereira, Martha Maria ^b  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

+ T cells; Atypical lymphocytes; Clinical features; Leptospirosis

Indexed keywords

ADULT; ARTICLE; ATYPICAL LYMPHOCYTOSIS; BRAZIL; CLINICAL ARTICLE; CLINICAL EXAMINATION; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DISEASE ASSOCIATION; ENDEMIC DISEASE; EPIDEMIC; FEMALE; GAMMA DELTA T LYMPHOCYTE; HOSPITAL PATIENT; HUMAN; LABORATORY TEST; LEPTOSPIROSIS; LYMPHOCYTOSIS; MALE; MORTALITY; OBSERVATIONAL STUDY; RETROSPECTIVE STUDY;

ADULT; BRAZIL; COHORT STUDIES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; LEPTOSPIROSIS; LYMPHOCYTOSIS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; T-LYMPHOCYTES; YOUNG ADULT;

ARBOVIRUS;

EID: 81455128144     PISSN: 00378682     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0037-86822011005000050     Document Type: Article

References (28)

1. Plank R, Dean D. Overview of the epidemiology, microbiology, and pathogenesis of Leptospira spp. in humans. Microb Infect 2000; 2:1265-1276.
2. Levett PN. Leptospirosis. Clin Microbiol Rev 2001; 14:296-326.
3. McBride A, Athanazio DA, Reis MG, Ko AI. Leptospirosis. Curr Opin Infect Dis 2005; 18:376-386.
4. Agampodi S, Peacock S. The potential emergence of leptospirosis in Sri Lanka. Lancet 2009; 9:524-526.
5. Wuthiekanun V, Sirisukkarn N, Daengsupa P, Sakaraserane P, Sangkakam A, Chierakul W, et al. Clinical diagnosis and geographic distribution of leptospirosis, Thailand Emerg Infect Dis 2007; 13:124-126.
6. Lemos ER, Rozental T, Villela CL. Brazilian spotted fever: description of a fatal clinical case in the State of Rio de Janeiro. Rev Soc Bras Med Trop 2002; 35:523-525.
7. Levett PN, Branch SL, Edwards CN. Detection of dengue infection in patients investigated for leptospirosis in Barbados. Am J Trop Med Hyg 2000; 62:112-114.
8. LaRocque RC, Breiman RF, Ari MD, Morey RE, Janan FA, Hayes JM, et al. Leptospirosis during dengue outbreak, Bangladesh. Emerg Infect Dis 2005; 11:766-769.
9. Clement J, Maes P, Muthusethupathi M, Nainan G, van Ranst M. First evidence of fatal Hantavirus nephropathy in India, mimicking leptospirosis. Nephrol Dial Transplant 2006; 21:826-827.
10. Vinetz JM. Ten common questions about leptospirosis. Inf Dis Clin Pract 2000; 9:59-65.
11. Gubler D. Dengue and Dengue hemorrhagic fever. Clin Microbiol Rev 1998; 11:480-496.
12. Barry M, Wisnewski AV, Matthias MA, Inouye SK, Vinetz JM. Suburban leptospirosis: atypical lymphocytosis and γδ T cell response. Clin Infect Dis 2007; 43:1304-1307.
13. Ministério da Saúde. Leptospirose: Diagnóstico e manejo clínico. Brasília: Secretaria de Vigilância em Saúde; 2009.
14. Kellum JA, Bellomo R, Ronco C. Definition and classification of acute kidney injury. Nephron Clin Pract 2008; 109:c182-c187.
15. Gonçalves AJ, Carvalho JE, Silva JBG, Rosembaum R, Vieira AR. Hemoptysis and adult respiratory distress syndrome as causes of death in leptospirosis: changes in the clinical and anatomical pathological patterns. Rev Soc Bras Med Trop 1992; 25:261-270.
16. Ko AI, Reis MG, Dourado CMR, Johnson Jr WD, Riley LW. Urban epidemic of severe leptospirosis in Brazil. Salvador Leptospirosis Study Group. Lancet 1999; 354:820-825.
17. Daher EF, Lima RSA, Silva Junior GB, Silva EC, Karbage NNN, Kataoka RS, et al. Clinical presentation of leptospirosis: a retrospective study of 201 patients in a metropolitan city of Brazil. Braz J Infect Dis 2010; 14:3-10.
18. Zaki SR, Shich WJ. Leptospirosis associated with outbreak of acute febrile illness and pulmonary haemorrhage, Nicaragua, 1995. The Epidemic Working Group at Ministry of Health in Nicaragua. Lancet 1996; 347:535-536.
19. Zavala-Velázquez J, Cárdenas-Marrufo M, Vado-Solís I, Cetina-Cámara M, Cano-Tur J, Laviada-Molina H. Hemorrhagic pulmonary leptospirosis: three cases from the Yucatan peninsula, Mexico. Rev Soc Bras Med Trop 2008; 41:404-408.
20. Simon MW. The atypical lymphocyte. Inter Pediatrics 2003; 18:20-22.
21. +. J Immunol 2003; 171:1447-1455.
22. Hayday AC. γδ Cells: A right time and a right place for a conserved third way of protection. Annu Rev Immunol 2000; 18:975-1026.
23. Born W, Cady C, Jones-Carson J, Lahn M, O'Brien R. Immunoregulatory functions of gamma delta T cells. Adv Immunol 1999; 71:77-144.
24. Venet F, Chung CS, Monneret G, Huang X, Horner B, Garber M, et al. Regulatory T cell populations in sepsis and trauma. J Leukoc Biol 2008; 83:523-535.
25. Sandor M, Sperling AI, Cook GA, Weinstock JV, Lynch RG, Bluestone JA. Two waves of gamma delta T cells expressing different V delta genes are recruited into Schistosome-induced liver granulomas. J Immunol 1995; 155: 275-284.
26. Tschöp J, Martignoni A, Goetzman HS, Choi LG, Wang Q, Noel JG, et al. Gammadelta T cells mitigate the organ injury and mortality of sepsis. J Leukoc Biol 2008; 83:581-588.
27. Belles C, Kuhl AK, Donoghue AJ, Sano Y, O'Brien RL, Born W, et al. Bias in the gamma delta T cell response to Listeria monocytogenes. V delta 6.3+ cells are a major component of the gamma delta T cell response to Listeria monocytogenes. J Immunol 1996; 156:4280-4289.
28. Poggi A, Catellani S, Musso A, Zocchi MR. Gammadelta T lymphocytes producing IFN-gamma and IL-17 in response to Candida albicans or mycobacterial antigens: possible implications for acute and chronic inflammation. Curr Med Chem 2009; 16:4743-4749.