Comparison of steroid substrates and inhibitors of P-glycoprotein by 3D-QSAR analysis

Journal of Molecular Structure

Volumn 733, Issue 1-3, 2005, Pages 111-118

  Li, Yan ^a   Wang, Yong Hua ^b   Yang, Ling ^b   Zhang, Shu Wei ^a   Liu, Chang Hou ^a   Yang, Sheng Li ^b  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

Comparative similarity index analysis; P glycoprotein; Partial least square; Steroid; Three dimensional quantitative structure activity relationship

Indexed keywords

GLYCOPROTEINS; STEROIDS;

DERIVATIVES; ENZYME INHIBITION; GLUCOSE; MOLECULAR STRUCTURE; SUBSTRATES;

PROTEINS;

16ALPHA METHYLPROGESTERONE; 17 HYDROXYPREGNENOLONE; 6,16ALPHA METHYLPREGNENOLONE; ALDOSTERONE; ANDROSTANOLONE; ANDROSTENEDIONE; ANDROSTERONE; CORTICOSTERONE; CORTODOXONE; DEOXYCORTICOSTERONE; DEXAMETHASONE; GLYCOPROTEIN P INHIBITOR; HYDROCORTISONE; HYDROXYPROGESTERONE; MEDROXYPROGESTERONE; MEDROXYPROGESTERONE ACETATE; PRASTERONE; PREGNANEDIONE; PREGNENOLONE; PROGESTERONE; STEROID; TESTOSTERONE; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE STUDY; CORRELATION ANALYSIS; DRUG STRUCTURE; PHYSICAL CHEMISTRY; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STANDARDIZATION;

EID: 8144230162     PISSN: 00222860     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molstruc.2004.08.012     Document Type: Article

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