Impact of systemic venous congestion in heart failure

Current Heart Failure Reports

Volumn 8, Issue 4, 2011, Pages 233-241

  Dupont, Matthias ^a   Mullens, Wilfried ^b,c   Tang, W H Wilson ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b DEPARTMENT OF CARDIOLOGY   (Belgium)

^c HASSELT UNIVERSITY   (Belgium)

Author keywords

Cardiorenal syndrome; Diagnostics; Diuretics; Early detection; Edema; Heart failure; Myocardial infarction; Prevention; Treatment; Venous congestion

Indexed keywords

AMINOTRANSFERASE; ARGIPRESSIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIURETIC AGENT; HYDRALAZINE; NESIRITIDE; NITRATE; NITROPRUSSIDE SODIUM;

AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; ANOREXIA; ARTICLE; ASCITES; CARDIAC PATIENT; CARDIAC RESYNCHRONIZATION THERAPY; CARDIOGENIC SHOCK; CELL ACTIVATION; CHRONIC KIDNEY DISEASE; CONGESTIVE HEART FAILURE; DISEASE COURSE; DYSPNEA; ENDOTHELIUM CELL; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HOSPITAL ADMISSION; HUMAN; LIVER FUNCTION TEST; MALABSORPTION; MITRAL VALVE REGURGITATION; NAUSEA; ORGAN PERFUSION; OXIDATIVE STRESS; PLEURA EFFUSION; PROGNOSIS; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SODIUM RESTRICTION; ULCER; ULTRAFILTRATION; VENOUS CONGESTION;

ANEMIA; CARDIOVASCULAR SYSTEM; DISEASE PROGRESSION; DIURETICS; HEART FAILURE; HEMOFILTRATION; HUMANS; HYPEREMIA; KIDNEY; LIVER; NEUROTRANSMITTER AGENTS; VASODILATOR AGENTS;

EID: 81355161361     PISSN: 15469530     EISSN: 15469549     Source Type: Journal    
DOI: 10.1007/s11897-011-0071-7     Document Type: Article

References (53)

1. J Lindenfeld NM Albert JP Boehmer, et al. 2010 Executive summary: HFSA 2010 comprehensive heart failure practice guideline J Card Fail. 16 475 539 10.1016/j.cardfail.2010.04.005
2. M Jessup WT Abraham DE Casey, et al. 2009 2009 focused update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation Circulation. 119 1977 2016 19324967 10.1161/CIRCULATIONAHA.109.192064
3. HM Krumholz EM Parent N Tu, et al. 1997 Readmission after hospitalization for congestive heart failure among Medicare beneficiaries Arch Intern Med. 157 99 104 8996046 10.1001/archinte.157.1.99 1:STN:280:DyaK2s7kvFagug%3D%3D (Pubitemid 27027080)
4. KF Adams Jr GC Fonarow CL Emerman, et al. 2005 Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE) Am Heart J. 149 209 216 15846257 10.1016/j.ahj.2004.08.005 (Pubitemid 40348525)
5. C-M Yu L Wang E Chau, et al. 2005 Intrathoracic impedance monitoring in patients with heart failure: correlation with fluid status and feasibility of early warning preceding hospitalization Circulation. 112 841 848 16061743 10.1161/CIRCULATIONAHA.104.492207 (Pubitemid 41170070)
6. PH Futcher HA Schroeder 1942 Studies on congestive heart failure, II: Impaired renal excretion of sodium chloride Am J Med Sci. 204 52 62 10.1097/00000441-194207000-00008 1:CAS:528:DyaH38XksVKmtA%3D%3D
7. E Braunwald WH Plauth Jr AG Morrow 1965 A method for the detection and quantification of impaired sodium excretion: results of an oral sodium tolerance test in normal subjects and in patients with heart disease Circulation. 32 223 231 14340948 1:CAS:528:DyaF2MXkvVejs74%3D
8. RW Schrier 1988 Pathogenesis of sodium and water retention in high-output and low-output cardiac failure, nephrotic syndrome, cirrhosis, and pregnancy (1) N Engl J Med. 319 1065 1072 3050518 10.1056/NEJM198810203191606 1:STN:280:DyaL1M%2FhsVKitw%3D%3D
9. M Packer 1992 The neurohormonal hypothesis: a theory to explain the mechanism of disease progression in heart failure J Am Coll Cardiol. 20 248 254 1351488 10.1016/0735-1097(92)90167-L 1:STN:280:DyaK383pvFyntw%3D%3D
10. RW Schrier WT Abraham 1999 Hormones and hemodynamics in heart failure N Engl J Med. 341 577 585 10451464 10.1056/NEJM199908193410806 1:CAS:528:DyaK1MXlvVOnsbY%3D (Pubitemid 29384167)
11. GS Francis C Benedict DE Johnstone, et al. 1990 Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure: a substudy of the Studies of Left Ventricular Dysfunction (SOLVD) Circulation. 82 1724 1729 2146040 10.1161/01.CIR.82.5.1724 1:STN:280:DyaK3M%2FivF2jug%3D%3D (Pubitemid 20367975)
12. DW Kitzman WC Little PH Brubaker, et al. 2002 Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure JAMA. 288 2144 2150 12413374 10.1001/jama.288.17.2144 (Pubitemid 35265382)
13. CW Yancy M Lopatin LW Stevenson, et al. 2006 Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function. A report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database J Am Coll Cardiol. 47 76 84 16386668 10.1016/j.jacc.2005.09.022 (Pubitemid 43005168)
14. K Hogg J McMurray 2005 Neurohumoral pathways in heart failure with preserved systolic function Prog Cardiovas Dis. 47 357 366 10.1016/j.pcad.2005. 02.001 1:CAS:528:DC%2BD2MXhtFSkt7bJ (Pubitemid 41188342)
15. K Damman AA Voors HL Hillege, et al. 2010 Congestion in chronic systolic heart failure is related to renal dysfunction and increased mortality Eur J Heart Fail. 12 974 982 20685688 10.1093/eurjhf/hfq118
16. C Lucas W Johnson MA Hamilton, et al. 2000 Freedom from congestion predicts good survival despite previous class IV symptoms of heart failure Am Heart J. 140 840 847 11099986 10.1067/mhj.2000.110933 1:STN:280: DC%2BD3M%2Fnt1ajsQ%3D%3D
17. MH Drazner JE Rame LW Stevenson, et al. 2001 Prognostic importance of elevated jugular venous pressure and a third heart sound in patients with heart failure N Engl J Med. 345 574 581 11529211 10.1056/NEJMoa010641 1:STN:280:DC%2BD3Mvos1Oqug%3D%3D (Pubitemid 32772099)
18. JG Cleland K Swedberg F Follath, et al. 2003 The EuroHeart Failure survey programme - a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis Eur Heart J. 24 442 463 12633546 10.1016/S0195-668X(02)00823-0 1:STN:280:DC%2BD3s7itVWjug%3D%3D (Pubitemid 36286187)
19. GC Fonarow WT Abraham NM Albert, et al. 2004 Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF): rationale and design Am Heart J. 148 43 51 15215791 10.1016/j.ahj.2004.03.004 (Pubitemid 38900479)
20. JN Cohn DG Archibald S Ziesche, et al. 1986 Effect of vasodilator therapy on mortality in chronic congestive heart failure N Engl J Med. 314 1547 1552 3520315 10.1056/NEJM198606123142404 1:STN:280:DyaL283jtVOjtw%3D%3D
21. W Mullens Z Abrahams GS Francis, et al. 2009 Usefulness of Isosorbide Dinitrate and Hydralazine as add-on therapy in patients discharged for advanced decompensated heart failure Am J Cardiol. 103 8 1113 1119 19361599 10.1016/j.amjcard.2008.12.028 1:CAS:528:DC%2BD1MXktl2jsbY%3D
22. AL Taylor S Ziesche C Yancy, et al. 2004 Combination of isosorbide dinitrate and hydralazine in blacks with heart failure N Engl J Med. 351 20 2049 2057 15533851 10.1056/NEJMoa042934 1:CAS:528:DC%2BD2cXpslegsrs%3D (Pubitemid 39482498)
23. JG Cleland JC Daubert E Erdmann, et al. 2005 The effect of cardiac resynchronisation on morbidity and mortality in heart failure N Engl J Med. 352 1539 1549 15753115 10.1056/NEJMoa050496 1:CAS:528:DC%2BD2MXjtFGnsLo%3D (Pubitemid 40517094)
24. LB Rosario LW Stevenson SD Solomon, et al. 1998 The mechanism of decrease in dynamic mitral regurgitation during heart failure treatment: importance of reduction in the regurgitant orifice size J Am Coll Cardiol. 32 1819 1824 9857857 10.1016/S0735-1097(98)00461-6 1:STN:280:DyaK1M%2FntlGlug%3D%3D (Pubitemid 29010440)
25. PC Colombo JE Banchs S Celaj, et al. 2005 Endothelial cell activation in patients with decompensated heart failure Circulation. 111 1 58 62 15611373 10.1161/01.CIR.0000151611.89232.3B 1:CAS:528:DC%2BD2cXhtFeisLrJ (Pubitemid 40070844)
26. A Ganda D Onat RT Demmer, et al. 2010 Venous congestion and endothelial cell activation in acute decompensated heart failure Curr Heart Fail Rep. 7 66 74 20424989 10.1007/s11897-010-0009-5 1:CAS:528:DC%2BC3cXht1CjsL3J This review highlights the current evidence and pathophysiologic mechanisms for endothelial cell activation as a consequence of venous congestion
27. HL Hillege D Nitsch MA Pfeffer, et al. 2006 Renal function as a predictor of outcome in a broad spectrum of patients with heart failure Circulation. 113 671 678 16461840 10.1161/CIRCULATIONAHA.105.580506
28. DE Forman J Butler Y Wang, et al. 2004 Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure J Am Coll Cardiol. 43 61 67 14715185 10.1016/j.jacc.2003.07. 031 (Pubitemid 38045917)
29. FR Winton 1931 The influence of venous pressure on the isolated mammalian kidney J Physiol. 72 49 61 16994199 1:CAS:528:DyaA38XhtlSj
30. K Damman VM Van Deursen G Navis, et al. 2009 Increased central venous pressure is associated with impaired renal function and mortality in a broad spectrum of patients with cardiovascular disease J Am Coll Cardiol. 53 582 588 19215832 10.1016/j.jacc.2008.08.080 Together with reference 31, this article shifted attention from low cardiac output to venous congestion as THE most important hemodynamic cause of renal dysfunction in heart failure. This article demonstrates a correlation between increased CVP and impaired renal function in a broad spectrum of patients with cardiovascular disease
31. W Mullens Z Abrahams GS Francis, et al. 2009 Importance of venous congestion for worsening of renal function in advanced decompensated heart failure J Am Coll Cardiol. 53 589 596 19215833 10.1016/j.jacc.2008.05.068 Together with reference 30, this article shifted attention from low cardiac output to venous congestion as the most important hemodynamic cause of renal dysfunction in heart failure. This article points to CVP as the most important hemodynamic variable associated with worsening renal function
32. JM Testani AV Khera MG St John Sutton, et al. 2010 Effect of right ventricular function and venous congestion on cardiorenal interactions during the treatment of decompensated heart failure Am J Cardiol. 105 4 511 516 20152246 10.1016/j.amjcard.2009.10.020
33. W Mullens Z Abrahams H Skouri, et al. 2008 Elevated intra-abdominal pressure in acute decompensated heart failure: a potential contributor to worsening renal function? J Am Coll Cardiol. 51 300 306 18206740 10.1016/j.jacc.2007.09.043 This study demonstrated a correlation between elevated intra-abdominal pressures and worsening renal function. This is a new concept, at least in heart failure patients
34. W Mullens Z Abrahams GS Francis, et al. 2008 Prompt reduction in intra-abdominal pressure following large-volume mechanical fluid removal improves renal insufficiency in refractory decompensated heart failure J Card Fail. 14 6 508 514 18672199 10.1016/j.cardfail.2008.02.010 (Pubitemid 352040863)
35. BM Massie CM O'Connor M Metra, et al. 2010 Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure N Engl J Med. 363 15 1419 28 20925544 10.1056/NEJMoa0912613
36. RK Seeto B Fenn DC Rockey 2000 Ischemic hepatitis: clinical presentation and pathogenesis Am J Med. 109 109 113 10967151 10.1016/S0002-9343(00)00461-7 1:STN:280:DC%2BD3cvosV2hsA%3D%3D
37. LA Allen GM Felker S Pocock, et al. 2009 Liver function abnormalities and outcome in patients with chronic heart failure: data from the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) program Eur J Heart Fail. 11 170 177 19168515 10.1093/eurjhf/hfn031
38. GT Lau HC Tan L Kritharides 2002 Type of liver dysfunction in heart failure and its relation to the severity of tricuspid regurgitation Am J Cardiol. 90 1405 1409 12480058 10.1016/S0002-9149(02)02886-2 (Pubitemid 35449493)
39. BD Westenbrink FW Visser AA Voors, et al. 2005 Anaemia in chronic heart failure is not only related to impaired renal perfusion and blunted erythropoietin production, but to fluid retention as well Eur Heart J. 26 2232 2237 10.1093/eurheartj/ehi388 (Pubitemid 41541385)
40. LW Stevenson JK Perloff 1989 The limited reliability of physical signs for estimating hemodynamics in chronic heart failure JAMA. 261 884 888 2913385 10.1001/jama.261.6.884 1:STN:280:DyaL1M7htFahsQ%3D%3D (Pubitemid 19046417)
41. SI Chaudhry JA Mattera JP Curtis, et al. 2010 Telemonitoring in patients with heart failure N Engl J Med. 363 2301 2309 21080835 10.1056/NEJMoa1010029 1:CAS:528:DC%2BC3cXhsFGkt7%2FM This trial, and the accompanying editorial, nicely point out the current limitations and requirements for optimal telemonitoring
42. WT Abraham PB Adamson RC Bourge, et al. 2011 Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial Lancet. 377 658 666 21315441 10.1016/S0140-6736(11)60101-3 This recent study serves as proof of concept that early intervention, based on hemodynamic data, can avoid hospital admission due to ADHF
43. RC Bourge WT Abraham PB Adamson, et al. 2008 Randomized controlled trial of an implantable continuous hemodynamic monitor in patients with advanced heart failure: the COMPASS-HF study J Am Coll Cardiol. 51 1073 1079 18342224 10.1016/j.jacc.2007.10.061 (Pubitemid 351374766)
44. GS Francis RM Siegel SR Goldsmith, et al. 1985 Acute vasoconstrictor response to intravenous furosemide in patients with chronic congestive heart-failure - activation of the neurohumoral axis Ann Intern Med. 103 1 6 2860833 1:STN:280:DyaL2M3itlCrsA%3D%3D (Pubitemid 15068490)
45. SS Gottlieb DC Brater I Thomas, et al. 2002 BG9719 (CVT-124), an A(1) adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy Circulation. 105 1348 1353 11901047 10.1161/hc1102.105264 1:CAS:528:DC%2BD38XjtFalsL4%3D (Pubitemid 34260427)
46. S Eshaghian TB Horwich GC Fonarow 2006 Relation of loop diuretic dose to mortality in advanced heart failure Am J Cardiol. 97 1759 1764 16765130 10.1016/j.amjcard.2005.12.072 1:CAS:528:DC%2BD28XlsVeltL0%3D (Pubitemid 43817867)
47. P Agostoni G Marenzi G Lauri, et al. 1994 A Sustained improvement in functional capacity after removal of body fluid with isolated ultrafiltration in chronic cardiac insufficiency: failure of furosemide to provide the same result Am J Med. 96 3 191 199 8154506 10.1016/0002-9343(94)90142-2 1:CAS:528:DyaK2MXpsVWgsLg%3D
48. MR Costanzo ME Guglin MT Saltzberg, et al. 2007 Ultrafiltration versus intravenous diuretics for patients hospitalized for acute decompensated heart failure J Am Coll Cardiol. 49 675 683 17291932 10.1016/j.jacc.2006.07.073 1:CAS:528:DC%2BD2sXhs1Slt7g%3D (Pubitemid 46205043)
49. M Vanderheyden R Houben S Verstreken, et al. 2010 Continuous monitoring of intrathoracic impedance and right ventricular pressures in patients with heart failure Circ Heart Fail. 3 3 370 377 20197559 10.1161/CIRCHEARTFAILURE. 109.867549
50. W Mullens Z Abrahams GS Francis, et al. 2008 Sodium nitroprusside for advanced low-output heart failure J Am Coll Cardiol. 52 3 200 207 18617068 10.1016/j.jacc.2008.02.083 1:CAS:528:DC%2BD1cXosVOgu7k%3D (Pubitemid 351915785)
51. Publication committee for the VMAC investigators 2002 Intravenous neseritide versus nitroglycerin for treatment of decompensated congestive heart failure: the VMAC trial JAMA. 287 1531 1540 10.1001/jama.287.12.1531
52. C Binanay RM Califf V Hasselblad, et al. 2005 Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial JAMA. 294 13 1625 1633 16204662 10.1001/jama.294.13.1625 (Pubitemid 41407355)
53. JM Testani J Chen BD McCauley, et al. 2010 Potential effects of aggressive decongestion during the treatment of decompensated heart failure on renal function and survival Circulation. 122 3 265 272 20606118 10.1161/CIRCULATIONAHA.109.933275