메뉴 건너뛰기




Volumn 124, Issue 20, 2011, Pages 2202-2207

Reduction in mortality in subjects with homozygous familial hypercholesterolemia associated with advances in lipid-lowering therapy

Author keywords

hypercholesterolemia, familial; lipid lowering therapy; mortality; statins

Indexed keywords

ATORVASTATIN; EZETIMIBE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; ROSUVASTATIN; SIMVASTATIN;

EID: 81355160365     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.111.042523     Document Type: Article
Times cited : (315)

References (32)
  • 1
    • 0000600880 scopus 로고    scopus 로고
    • Familial hypercholesterolemia
    • Scriver CR, Beaudet AL, Sly WS, Valle D, eds 8th ed. New York, NY: McGraw-Hill
    • Goldstein JL, Hobb HH, Brown MS. Familial hypercholesterolemia. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic and Molecular Bases of Inherited Disease. 8th ed. New York, NY: McGraw-Hill; 2001: 2863-2913.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease , pp. 2863-2913
    • Goldstein, J.L.1    Hobb, H.H.2    Brown, M.S.3
  • 2
    • 0041743167 scopus 로고    scopus 로고
    • Monogenic hypercholesterolemia: New insights in pathogenesis and treatment
    • DOI 10.1172/JCI200318925
    • Rader DJ, Cohen J, Hobbs HH. Monogenic hypercholesterolemia: new insights in pathogenesis and treatment. J Clin Invest. 2003;111: 1795-1803. (Pubitemid 38057721)
    • (2003) Journal of Clinical Investigation , vol.111 , Issue.12 , pp. 1795-1803
    • Rader, D.J.1    Cohen, J.2    Hobbs, H.H.3
  • 3
    • 0019190534 scopus 로고
    • A host of hypercholesterolaemic homozygotes in South Africa
    • Seftel HC, Baker SG, Sandler MP, Forman MB, Joffe BI, Mendelsohn D, Jenkins T, Meiny CJ. A host of hypercholesterolaemic homozygotes in South Africa. BMJ. 1980;281:633-636. (Pubitemid 10051766)
    • (1980) British Medical Journal , vol.281 , Issue.6241 , pp. 633-636
    • Seftel, H.C.1    Baker, S.G.2    Sandler, M.P.3
  • 4
    • 0024408098 scopus 로고
    • Three mutations that cause familial hypercholesterolaemia in Afrikaners identified - A milstone in South African medicine
    • Gevers W. Three mutations that cause familial hypercholesterolemia in Afrikaners identified: a milestone in South African medicine. S Afr Med J. 1989;76:393-394. (Pubitemid 20003455)
    • (1989) South African Medical Journal , vol.76 , Issue.8 , pp. 393-394
    • Gevers, W.1
  • 5
    • 33645225775 scopus 로고    scopus 로고
    • Lowering LDL not only how low, but how long?
    • Brown MS, Goldstein JL. Lowering LDL: not only how low, but how long? Science. 2006;311:1721-1723.
    • (2006) Science. , vol.311 , pp. 1721-1723
    • Brown, M.S.1    Goldstein, J.L.2
  • 6
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins
    • Cholesterol Treatment Trialists' (CTT) Collaborators
    • Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C, Kirby A, Sourjina T, Peto R, Collins R, Simes R; Cholesterol Treatment Trialists' (CTT) Collaborators. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins. Lancet. 2005;366:1267-1278.
    • (2005) Lancet. , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3    Blackwell, L.4    Buck, G.5    Pollicino, C.6    Kirby, A.7    Sourjina, T.8    Peto, R.9    Collins, R.10    Simes, R.11
  • 7
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170 000 participants in 26 randomised trials
    • Cholesterol Treatment Trialists' (CTT) Collaboration
    • Baigent C, Blackwell L, Emberson J, Holland LE, Reith C, Bhala N, Peto R, Barnes EH, Keech A, Simes R, Collins R; Cholesterol Treatment Trialists' (CTT) Collaboration. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials. Lancet. 2010;376:1670-1681.
    • (2010) Lancet. , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3    Holland, L.E.4    Reith, C.5    Bhala, N.6    Peto, R.7    Barnes, E.H.8    Keech, A.9    Simes, R.10    Collins, R.11
  • 10
    • 39649084902 scopus 로고    scopus 로고
    • A dose-titration and comparative study of rosuvastatin and atorvastatin in patients with homozygous familial hypercholesterolaemia
    • DOI 10.1016/j.atherosclerosis.2007.06.028, PII S0021915007004005
    • Marais AD, Raal FJ, Stein EA, Rader DJ, Blasetto J, Palmer M, Wilp-shaarf W. A dose-titration and comparative study of rosuvastatin and atorvastatin in patients with homozygous familial hypercholesterolemia. Atherosclerosis. 2008;197:400-406. (Pubitemid 351284477)
    • (2008) Atherosclerosis , vol.197 , Issue.1 , pp. 400-406
    • Marais, A.D.1    Raal, F.J.2    Stein, E.A.3    Rader, D.J.4    Blasetto, J.5    Palmer, M.6    Wilpshaar, W.7
  • 11
    • 0037188567 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia
    • DOI 10.1161/01.CIR.0000018744.58460.62
    • Gagné C, Gaudet D, Bruckert E; for the Ezetimibe Study Group. Efficacy and safety of ezetimibe coadministered with atorvastatin in patients with homozygous familial hypercholesterolemia. Circulation. 2002;105: 2469-2475. (Pubitemid 34568966)
    • (2002) Circulation , vol.105 , Issue.21 , pp. 2469-2475
    • Gagne, C.1    Gaudet, D.2    Bruckert, E.3
  • 13
    • 0035197537 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor gene (LDLR) world-wide website in familial hypercholesterolaemia: Update, new features and mutation analysis
    • DOI 10.1016/S0021-9150(00)00647-X, PII S002191500000647X
    • Heath KE, Gahan M, Whitall RA, Humphries SE. Low-density lipoprotein receptor gene (LDLR) world-wide website in familial hypercholesterolemia: update, new features and mutational analysis. Atherosclerosis. 2001;154: 243-246. (Pubitemid 32008586)
    • (2001) Atherosclerosis , vol.154 , Issue.1 , pp. 243-246
    • Heath, K.E.1    Gahan, M.2    Whittall, R.A.3    Humphries, S.E.4
  • 14
    • 0015348189 scopus 로고
    • Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI, Frederickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
    • (1972) Clin Chem. , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Frederickson, D.S.3
  • 15
    • 0029008387 scopus 로고
    • Nonradioactive multiplex PCR screening strategy for the simultaneous detection of multiple low density lipoprotein receptor gene mutations
    • Kotze MJ, Theart L, Callis M, Peeters AV, Theart R, Langenhoven E. Nonradioactive multiplex PCR screening strategy for the simultaneous detection of multiple low density lipoprotein receptor gene mutations. PCR Methods Appl. 1995;4:352-356.
    • (1995) PCR Methods Appl. , vol.4 , pp. 352-356
    • Kotze, M.J.1    Theart, L.2    Callis, M.3    Peeters, A.V.4    Theart, R.5    Langenhoven, E.6
  • 17
    • 0035937832 scopus 로고    scopus 로고
    • The molecular mechanism for the genetic disorder familial defective apolipo-protein B 100
    • Boren J, Ekstrom U, Agren B, Nilsson-Ehle P, Innerarity TL. The molecular mechanism for the genetic disorder familial defective apolipo-protein B 100. J Biol Chem. 2001;275:9214-9218.
    • (2001) J Biol Chem. , vol.275 , pp. 9214-9218
    • Boren, J.1    Ekstrom, U.2    Agren, B.3    Nilsson-Ehle, P.4    Innerarity, T.L.5
  • 18
    • 33846898754 scopus 로고    scopus 로고
    • Autosomal recessive hypercholesterolaemia: Discrimination of ARH protein and LDLR function in the homozygous FH phenotype
    • DOI 10.1016/j.cca.2006.10.005, PII S0009898106006929
    • Abera AB, Marais AD, Raal FJ, Leisegang F, Jones S, George P, Henderson HE. Autosomal recessive hypercholesterolemia: discrimination of ARH protein and LDLR function in the homozygous FH phenotype. Clin Chem Acta. 2007;378:33-37. (Pubitemid 46241057)
    • (2007) Clinica Chimica Acta , vol.378 , Issue.1-2 , pp. 33-37
    • Abera, A.B.1    Marais, A.D.2    Raal, F.J.3    Leisegang, F.4    Jones, S.5    George, P.6    Henderson, H.E.7
  • 19
    • 55749088063 scopus 로고    scopus 로고
    • Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercho-lesterolemia: A prospective registry study
    • on behalf of the Simon Broome Familial Hyperlipi-daemia Register Group
    • Neil A, Cooper J, Betteridge J, Capps N, McDowell I, Durrington P, Seed M, Humphries SE; on behalf of the Simon Broome Familial Hyperlipi-daemia Register Group. Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercho-lesterolemia: a prospective registry study, Eur Heart J, 2008, 29, 2625-2633.
    • (2008) Eur Heart J , vol.29 , pp. 2625-2633
    • Neil, A.1    Cooper, J.2    Betteridge, J.3    Capps, N.4    McDowell, I.5    Durrington, P.6    Seed, M.7    Humphries, S.E.8
  • 21
    • 0014693152 scopus 로고
    • Risks of ischaemic heart disease in familial hyperlipidaemic states
    • Slack J. Risks of ischaemic heart disease in familial hyperlipidaemic states. Lancet. 1969;2:1380-1382.
    • (1969) Lancet. , vol.2 , pp. 1380-1382
    • Slack, J.1
  • 22
    • 0017349605 scopus 로고
    • Failure of complete bile diversion and oral bile acid therapy in the treatment of homozygous familial hypercholesterolemia
    • Deckelbaum RJ, Lees RS, Small DM, Hedberg Se, Grundy SM. Failure of complete bile diversion and oral bile acid therapy in the treatment of homozygous hypercholesterolemia. N Engl J Med. 1977;296:465-470. (Pubitemid 8038307)
    • (1977) New England Journal of Medicine , vol.296 , Issue.9 , pp. 465-470
    • Deckelbaum, R.J.1    Lees, R.S.2    Small, D.M.3
  • 24
    • 78649390237 scopus 로고    scopus 로고
    • Lipoprotein apheresis
    • Thompson GR. Lipoprotein apheresis. Curr Opin Lipidol. 2010;21: 487-491.
    • (2010) Curr Opin Lipidol. , vol.21 , pp. 487-491
    • Thompson, G.R.1
  • 25
    • 0032535310 scopus 로고    scopus 로고
    • Long-term efficacy of low-density lipoprotein apheresis on coronary heart disease in familial hypercholesterolemia
    • DOI 10.1016/S0002-9149(98)00692-4, PII S0002914998006924
    • Mabuchi H, Koizumi J, Shimizu M, Kajinami K, Miyamoto S, Ueda K, Takegoshi T; Hokuriku FH-LDL-Apheresis Study Group. Long-term efficacy of low-density lipoprotein apheresis in coronary heart disease in familial hypercholesterolemia. Am J Cardiol. 1998;82:1489-1495. (Pubitemid 29006472)
    • (1998) American Journal of Cardiology , vol.82 , Issue.12 , pp. 1489-1495
    • Mabuchi, H.1    Koizumi, J.2    Shimizu, M.3    Kajinami, K.4    Miyamoto, S.5    Ueda, K.6    Takegoshi, T.7
  • 28
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;144: 1383-1389.
    • (1994) Lancet. , vol.144 , pp. 1383-1389
  • 32
    • 59649121269 scopus 로고    scopus 로고
    • Other therapies for reducing low-density lipoprotein cholesterol: Medications in development
    • Stein EA. Other therapies for reducing low-density lipoprotein cholesterol: medications in development. Endocrinol Metab Clin N Am. 2009;38:99-119.
    • (2009) Endocrinol Metab Clin N Am. , vol.38 , pp. 99-119
    • Stein, E.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.