MicroRNAs: A new mechanisms for regulation of lipid metabolism

Progress in Biochemistry and Biophysics

Volumn 38, Issue 9, 2011, Pages 781-790

  Chen, Wu Jun ^a   Yin, Kai ^a   Zhao, Guo Jun ^a   Tang, Chao Ke ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Cholesterol homeostasis; Fatty acid oxidation; HDL; microRNAs; Triglyceride metabolism

Indexed keywords

EID: 81355151437     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2011.00072     Document Type: Review

References (58)

1. Liao D F, Tang C K. Reverse Cholesterol Transport Bases and Clinics. Beijing: Science Press, 2009: 1-26
2. Bartel D P. MicroRNAs: target recognition and regulatory functions. Cell, 2009, 136(2): 215-233
3. Pang J H, Ren C H, Li Z F, et al. Prog Biochem Biophys, 2009, 36(2): 151-156
4. Zhou T H, Yang X H, Wu S J, et al. Prog Biochem Biophys, 2010, 37(2): 190-199
5. Yin K, Liao D, Tang C K. ATP-binding membrane cassette transporter A1 (ABCA1): A possible link between inflammation and reverse cholesterol transport. Mol Med. 2010, 16 (9-10): 438-449
6. Zelcer N, Hong C, Boyadjian R, et al. LXR regulates cholesterol uptake through idol-dependent ubiquitination of the LDL receptor. Science, 2009, 325(5936): 100-104
7. Wang Y, Rogers P M, Su C, et al. Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha. J Biol Chem, 2008, 283(39): 26332-26339
8. Horton J D, Goldstein J L, Brown MS, et al. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest, 2002, 109(9): 1125-1131 (Pubitemid 34496588)
9. Repa J J, Liang G, Ou J, et al. Regulation of mouse sterol regulatory element-binding protein-1c gene(SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev, 2000, 14(2): 2819-2830
10. HuY W, TangC K. Prog BiochemBiophys, 2008, 35(5): 373-379
11. Huang WT, Guo X Q, Dai J P, et al. Prog Biochem Biophys, 2010, 37(8): 826-833
12. Friedman R C, Farth K K. Burge C B, et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res, 2009, 19(1): 92-105
13. Lee Y, Ahn C, Han J, et al. The nuclear RNase?Drosha initiates microRNAprocessing. Nature, 2003, 425(6956): 415-419
14. Kim V N, Han J, Siomi M C, et al. Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol, 2009, 10(2): 126-139
15. Cifuentes D, Xue H, Tayior D W, et al. A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science, 2010, 328(5986): 1694-1698
16. Fu C, Lin K. Prog BiochemBiophys, 2009, 36(5):608-615
17. Forman J J, Coller H A. The code within the code: MicroRNAs target coding regions. Cell Cycle, 2010, 9(8): 1533-1541
18. Orom U A, Nielsen F C, Lund A H, et al. MicroRNA-10a binds the 5?UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell, 2008, 30(4): 460-471 (Pubitemid 351672378)
19. Lytle J R, Yario T A, Steitz J A, et al. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5?UTR as in the 3?UTR. Proc Natl Acad Sci USA, 2007, 104(23): 9667-9672 (Pubitemid 47175324)
20. Rigoutsos I. New tricks for animal microRNAS: targeting of amino acid coding regions at conserved and nonconserved sites. Cancer Res, 2009, 69(8): 3245-3248
21. Liu J. Control of protein synthesis and mRNA degradation by microRNAs. Curr Opin Cell Biol, 2008, 20(2): 214-221
22. Jopling C L, Yi M, Lancasrer A M, et al. Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA. Science, 2005, 309(5740): 1577-1581 (Pubitemid 41266486)
23. Vasudevan S, Tong Y, Steitz J A. Switching from repression to activation: microRNAs can up-regulate translation. Science, 2007, 318(5858): 1931-1934
24. Vasudevan S, Steitz J A. AU-rich-element-mediated up regulation of translation by FXR1 and Argonaute2. Cell, 2007, 128(6): 1105-1118 (Pubitemid 46427873)
25. Vasudevan S, Tong Y, Steitz J A. Cell-cycle control of microRNAmediated translation regulation. Cell Cycle, 2008, 7 (11): 1545-1549 (Pubitemid 351881318)
26. von Roretz C, Gallouzi I E. Decoding ARE-mediated decay: is microRNA part of the equation?. J Cell Biol, 2008, 181(2): 189-194 (Pubitemid 351574545)
27. Marquart T J, Allen R M, Ory D S, et al. miR-33 links SREBP-2 induction to repression of sterol transporters. Proc Natl Acad Sci USA, 2010, 107(27): 12228-12232
28. Michael S, Brown, Jin Ye, et al. Goldstein.HDL miR-ed Down by SREBP Introns. Science, 2010, 328(5985): 1495-1496
29. Rayner K J, Su?rez Y, D?valos A, et al. MiR-33 contributes to the regulation of cholesterol homeostasis. Science, 2010, 328 (5985): 1570-1573
30. Najafi-Shoushtari S H, Kristo F, Li Y, et al. MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science, 2010, 328(5985): 1566-1569
31. Horie T, Ono K, Horiguchi M, et al. MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo. Proc Natl Acad Sci USA, 2010, 107 (40): 17321-17326
32. MooreK J, Rayner K J, Su?rez Y, et al. microRNAs and cholesterol metabolism. Trends Endocrinol Metab, 2010, 21(12): 699-706
33. Fern?ndez-Hernando C, Su?rez Y, Rayner K J, et al. MicroRNAs in lipid metabolism. Curr Opin Lipidol, 2011, 22(2): 86-92
34. Najafi-Shoushtari S H. MicroRNAs in cardiometabolic disease. curr atheroscler rep, 2011, 13(3): 202-207
35. Hu Y W, Ma X, Li X X, et al. Eicosapentaenoic acid reduces ABCA1 serine phosphorylation and impairs ABCA1-dependent cholesterol efflux through cyclic AMP/protein kinase A signaling pathway in THP-1 macrophage-derived foamcells. Atherosclerosis. 2009, 204(2): e35-e43
36. Liu X H, Xiao J, Mo Z C, et al. Contribution of D4-F to ABCA1 expression and cholesterol efflux in THP-1 macrophage-derived foamcells. J Cardiovasc Pharmacol, 2010, 56(3): 309-319
37. Liu X H, TangC K. Prog Physiol Sci, 2009, 40(3): 229-233
38. Chen S G, Xiao J, Liu X H, et al. Ibrolipim increases ABCA1/G1 expression by the LXR? signaling pathway in THP-1 macrophagederived foamcell. Acta Pharmacol Sin, 2010, 31(10): 1343-1349
39. Hu Y W, Wang Q, Ma X, et al. TGF-beta1 Up-regulates expression of ABCA1, ABCG1 and SR-BI through Liver X receptor alpha signaling pathway in THP-1 macrophage-derived foam cells. J Atheroscler Thromb, 2010, 17(5): 493-502
40. Li XY, TangC K. Chemistry of Life, 2008, 28(5): 633-636
41. Ou X, Dai X Y, Long Z F, et al. Sci China C Life Sci, 2008, 38(4): 356-367
42. Jelinek D, Patrick S M, Kitt K N, et al. Physiological and coordinate downregulation of the NPC1 and NPC2 genes are associated with the sequestration of LDL-derived cholesterol within endocytic compartments. J Cell Biochem, 2009, 108(5): 1102-1116
43. Dai X Y, Ou X, Hao X R, et al. The effect of T0901317 on ATP-binding cassette transporter A1 and niemann-pick type C1 in apoE-/- mice. J Cardiovasc Pharmacol, 2008, 51(5): 467-475
44. Gerin I, Clerbaux L A, Haumont O, et al. Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J Biol Chem, 2010, 285(44): 33652-33661
45. Shin C, Nam J W, Farh K K, et al. Expanding the microRNA targeting code: functional sites with centered pairing. Mol Cell, 2010, 38(6): 789-802
46. Ho P C, Chang K C, Chuang Y S, et al. Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production. FASEB J, 2011, 25(5): 1758-1766
47. Rosell M, Jones M C, Parker M G. Role of nuclear receptor corepressor RIP140 in metabolic syndrome. BiochimBiophys Acta, 2011, 1812(8): 919-928
48. Xing Y, Zhao S P. Chin J Arterioscler, 2010, 18(7): 586-588
49. Iliopoulos D, Drosato K, Hiyama Y, et al. MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism. J Lipid Res, 2010, 51(6): 1513-1523
50. Chen T, Huang Z, Wang L. MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages. Cardiovascular Res, 2009, 83(1): 131-139
51. Bowden K, Ridgway N D. OSBP negatively regulates ABCA1 protein stability. J Biol Chem, 2008, 283(26): 18210-18217
52. Wu Z S, Yang G S. microRNA-27b negatively regulate adipocyte differentiation through targentng PPAR?. Shanxi Yangling: Northwest A&F University, 2009
53. Karbiener M, Fischer C, Nowitsch S, et al. microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma. BiochemBiophys Res Commun, 2009, 390(2): 247-251
54. KimS Y, KimA Y, Lee H W, et al. miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression. Biochem Biophys Res Commun, 2010, 392 (3): 323-328
55. Ji J, Zhang J, Huang G, et al. Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett, 2009, 583(4): 759-766
56. Liu M X, Zhang WG, Liu L T. Chin J Arterioscler, 2009, 17(11): 902-906
57. Yi G H, Yang Y Z, Tang C K, et al. Chin J Arterioscler, 2003, 11(4): 325-329
58. Ling H Y, Ou H S, Feng S D, et al. Changes in microRNA profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes. Clin Exp Pharmacol Physiol, 2009, 36: e32-e36