메뉴 건너뛰기




Volumn 6, Issue 4, 2011, Pages 231-240

Enteropathy-associated T-cell lymphoma: Epidemiology, clinical features, and current treatment strategies

Author keywords

ASCT; Autologous stem cell transplantation; Clinical features; Conservative treatment with surgery and anthracycline based chemotherapy; EATL; Enteropathy associated T cell lymphoma; Epidemiology; HDCT; High dose chemotherapy; Survival

Indexed keywords

ANTHRACYCLINE; CD103 ANTIGEN; CD3 ANTIGEN; CD30 ANTIGEN; CD5 ANTIGEN; CD7 ANTIGEN; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; IFOSFAMIDE; METHOTREXATE; VINCRISTINE;

EID: 81355148871     PISSN: 15588211     EISSN: 1558822X     Source Type: Journal    
DOI: 10.1007/s11899-011-0097-7     Document Type: Review
Times cited : (50)

References (50)
  • 2
    • 0033975356 scopus 로고    scopus 로고
    • Enteropathy-type intestinal T-cell lymphoma: Clinical features and treatment of 31 patients in a single center
    • J Gale PD Simmonds GM Mead JW Sweetenham DH Wright 2000 Enteropathy-type intestinal T-cell lymphoma: clinical features and treatment of 31 patients in a single center J Clin Oncol. 18 795 803 10673521 1:STN:280:DC%2BD3c7jvFCrtg%3D%3D (Pubitemid 30106610)
    • (2000) Journal of Clinical Oncology , vol.18 , Issue.4 , pp. 795-803
    • Gale, J.1    Simmonds, P.D.2    Mead, G.M.3    Sweetenham, J.W.4    Wright, D.H.5
  • 3
    • 0027483503 scopus 로고
    • Primary lymphoma of the small intestine: A clinicopathological study of 119 cases
    • P Domizio RA Owen NA Shepherd IC Talbot AJ Norton 1993 Primary lymphoma of the small intestine. A clinicopathological study of 119 cases Am J Surg Pathol. 17 429 442 8470758 10.1097/00000478-199305000-00001 1:STN:280: DyaK3s3ivVWmtw%3D%3D (Pubitemid 23121773)
    • (1993) American Journal of Surgical Pathology , vol.17 , Issue.5 , pp. 429-442
    • Domizio, P.1    Owen, R.A.2    Shepherd, N.A.3    Talbot, I.C.4    Norton, A.J.5
  • 4
    • 13644269831 scopus 로고    scopus 로고
    • Gastrointestinal lymphoma: Where morphology meets molecular biology
    • DOI 10.1002/path.1703
    • PG Isaacson MQ Du 2005 Gastrointestinal lymphoma: where morphology meets molecular biology J Pathol. 205 255 274 15643667 10.1002/path.1703 1:CAS:528:DC%2BD2MXhsFOgsrg%3D (Pubitemid 40227996)
    • (2005) Journal of Pathology , vol.205 , Issue.2 , pp. 255-274
    • Isaacson, P.G.1    Du, M.-Q.2
  • 5
    • 0037139469 scopus 로고    scopus 로고
    • Risk of non-Hodgkin lymphoma in celiac disease
    • 11903028 10.1001/jama.287.11.1413
    • C Catassi E Fabiani G Corrao, et al. 2002 Risk of non-Hodgkin lymphoma in celiac disease JAMA. 287 1413 11903028 10.1001/jama.287.11.1413
    • (2002) JAMA. , vol.287 , pp. 1413
    • Catassi, C.1    Fabiani, E.2    Corrao, G.3
  • 6
    • 33947185256 scopus 로고    scopus 로고
    • Clinical value of immunoglobulin A antitransglutaminase assay in the diagnosis of celiac disease
    • DOI 10.1542/peds.2006-0604
    • A Diamanti F Colistro A Calce, et al. 2006 Clinical value of immunoglobulin A antitransglutaminase assay in the diagnosis of celiac disease Pediatrics. 118 e1696 e1700 17074840 10.1542/peds.2006-0604 (Pubitemid 46397543)
    • (2006) Pediatrics , vol.118 , Issue.6
    • Diamanti, A.1    Colistro, F.2    Calce, A.3    Devito, R.4    Ferretti, F.5    Minozzi, A.6    Santoni, A.7    Castro, M.8
  • 7
    • 35548980455 scopus 로고    scopus 로고
    • Medical progress: Celiac disease
    • DOI 10.1056/NEJMra071600
    • PH Green C Cellier 2007 Celiac disease N Engl J Med. 357 1731 1743 17960014 10.1056/NEJMra071600 1:CAS:528:DC%2BD2sXht1alsLjN (Pubitemid 350005154)
    • (2007) New England Journal of Medicine , vol.357 , Issue.17 , pp. 1731-1743
    • Green, P.H.R.1    Cellier, C.2
  • 9
    • 0022160002 scopus 로고
    • Malignant histiocytosis of the intestine
    • 4067739 10.1002/path.1711470311 1:STN:280:DyaL28%2Fmt1Skuw%3D%3D
    • PG Isaacson 1985 Malignant histiocytosis of the intestine J Pathol. 147 3 227 228 4067739 10.1002/path.1711470311 1:STN:280:DyaL28%2Fmt1Skuw%3D%3D
    • (1985) J Pathol. , vol.147 , Issue.3 , pp. 227-228
    • Isaacson, P.G.1
  • 15
    • 54349089022 scopus 로고    scopus 로고
    • Incidence of enteropathy-associated T-cell lymphoma: A nation-wide study of a population-based registry in the Netherlands
    • 18618372 10.1080/00365520802240222
    • WH Verbeek JM Van De Water A Al-Toma JJ Oudejans CJ Mulder VM Coupe 2008 Incidence of enteropathy-associated T-cell lymphoma: a nation-wide study of a population-based registry in The Netherlands Scand J Gastroenterol. 43 1322 1328 18618372 10.1080/00365520802240222
    • (2008) Scand J Gastroenterol. , vol.43 , pp. 1322-1328
    • Verbeek, W.H.1    Van De Water, J.M.2    Al-Toma, A.3    Oudejans, J.J.4    Mulder, C.J.5    Coupe, V.M.6
  • 17
    • 34948909526 scopus 로고    scopus 로고
    • Survival in refractory coeliac disease and enteropathy-associated T-cell lymphoma: Retrospective evaluation of single-centre experience
    • DOI 10.1136/gut.2006.114512
    • A Al-Toma WH Verbeek M Hadithi BM von Blomberg CJ Mulder 2007 Survival in refractory coeliac disease and enteropathy-associated T-cell lymphoma: retrospective evaluation of single-centre experience Gut. 56 1373 1378 17470479 10.1136/gut.2006.114512 1:STN:280:DC%2BD2srjvFCmtw%3D%3D (Pubitemid 47517830)
    • (2007) Gut , vol.56 , Issue.10 , pp. 1373-1378
    • Al-toma, A.1    Verbeek, W.H.M.2    Hadithi, M.3    Von Blomberg, B.M.E.4    Mulder, C.J.J.5
  • 19
    • 0032954284 scopus 로고    scopus 로고
    • Classification of intestinal T-cell neoplasms and their differential diagnosis
    • 9894471 1:STN:280:DyaK1M7htFynsA%3D%3D
    • A Chott M Vesely I Simonitsch I Mosberger H Hanak 1999 Classification of intestinal T-cell neoplasms and their differential diagnosis Am J Clin Pathol. 111 S68 S74 9894471 1:STN:280:DyaK1M7htFynsA%3D%3D
    • (1999) Am J Clin Pathol. , vol.111
    • Chott, A.1    Vesely, M.2    Simonitsch, I.3    Mosberger, I.4    Hanak, H.5
  • 20
    • 0023727525 scopus 로고
    • Enteropathy-associated T cell lymphoma (malignant histiocytosis of the intestine) is recognized by a monoclonal antibody (HML-1) that defines a membrane molecule on human mucosal lymphocytes
    • 3260750 1:STN:280:DyaL1c3nvFKktw%3D%3D
    • J Spencer N Cerf-Bensussan A Jarry, et al. 1988 Enteropathy-associated T cell lymphoma (malignant histiocytosis of the intestine) is recognized by a monoclonal antibody (HML-1) that defines a membrane molecule on human mucosal lymphocytes Am J Pathol. 132 1 5 3260750 1:STN:280:DyaL1c3nvFKktw%3D%3D
    • (1988) Am J Pathol. , vol.132 , pp. 1-5
    • Spencer, J.1    Cerf-Bensussan, N.2    Jarry, A.3
  • 21
    • 0030768736 scopus 로고    scopus 로고
    • Enteropathy associated T cell lymphoma
    • DH Wright 1997 Enteropathy associated T cell lymphoma Cancer Surv. 30 249 261 9547996 1:STN:280:DyaK1c3gvFaitQ%3D%3D (Pubitemid 27371546)
    • (1997) Cancer Surveys , vol.30 , pp. 249-261
    • Wright, D.H.1
  • 22
    • 0028843590 scopus 로고
    • Study of the immunohistochemistry and T cell clonality of enteropathy-associated T cell lymphoma
    • 7856760 1:STN:280:DyaK2M7mtVWnuw%3D%3D
    • A Murray EC Cuevas DB Jones DH Wright 1995 Study of the immunohistochemistry and T cell clonality of enteropathy-associated T cell lymphoma Am J Pathol. 146 509 519 7856760 1:STN:280:DyaK2M7mtVWnuw%3D%3D
    • (1995) Am J Pathol. , vol.146 , pp. 509-519
    • Murray, A.1    Cuevas, E.C.2    Jones, D.B.3    Wright, D.H.4
  • 23
    • 0028998178 scopus 로고
    • HLA-DRB, -DQA, and -DQB polymorphism in celiac disease and enteropathy-associated T-cell lymphoma. Common features and additional risk factors for malignancy
    • 7558926 10.1016/0198-8859(94)00130-I 1:STN:280:DyaK28%2FltlGitw%3D%3D
    • WM Howell ST Leung DB Jones, et al. 1995 HLA-DRB, -DQA, and -DQB polymorphism in celiac disease and enteropathy-associated T-cell lymphoma. Common features and additional risk factors for malignancy Hum Immunol. 43 29 37 7558926 10.1016/0198-8859(94)00130-I 1:STN:280:DyaK28%2FltlGitw%3D%3D
    • (1995) Hum Immunol. , vol.43 , pp. 29-37
    • Howell, W.M.1    Leung, S.T.2    Jones, D.B.3
  • 25
    • 77952578954 scopus 로고    scopus 로고
    • Evaluation of enteropathy-associated T-cell lymphoma comparing standard therapies with a novel regimen including autologous stem cell transplantation
    • 20197551 10.1182/blood-2009-07-231324 1:CAS:528:DC%2BC3cXms1egurg%3D The Scotland and Newcastle Lymphoma Group (SNLG) performed a detailed, population-based evaluation of patients with EATL registered with the group between 1994 and 1998. Data obtained included patient demographics, details on baseline evaluations, treatment, and patient outcomes. They also presented the results of novel first-line treatment with ifosfamide, etoposide, and epirubicin with intermediate-dose methotrexate followed by ASCT
    • M Sieniawski N Angamuthu K Boyd, et al. 2010 Evaluation of enteropathy-associated T-cell lymphoma comparing standard therapies with a novel regimen including autologous stem cell transplantation Blood 115 3664 3670 20197551 10.1182/blood-2009-07-231324 1:CAS:528:DC%2BC3cXms1egurg%3D The Scotland and Newcastle Lymphoma Group (SNLG) performed a detailed, population-based evaluation of patients with EATL registered with the group between 1994 and 1998. Data obtained included patient demographics, details on baseline evaluations, treatment, and patient outcomes. They also presented the results of novel first-line treatment with ifosfamide, etoposide, and epirubicin with intermediate-dose methotrexate followed by ASCT
    • (2010) Blood , vol.115 , pp. 3664-3670
    • Sieniawski, M.1    Angamuthu, N.2    Boyd, K.3
  • 26
    • 81355145140 scopus 로고    scopus 로고
    • Dose-dense induction followed by autologous stem cell transplant (ASCT) leads to sustained remissions in a large fraction of patients with previously untreated peripheral T-cell lymphomas (PTCLs) - Overall and subtype specific results of a phase II study from the Nordic Lymphoma Group
    • This is an interim analysis of a big, multicenter, prospective study on dose-dense induction with CHOEP-14 followed by ASCT in patients with PTCL. Among the 160 patients included were 21 patients with EATL.
    • • D'Amore F, Lauritzen G, Jantunen E, et al. Dose-dense induction followed by autologous stem cell transplant (ASCT) leads to sustained remissions in a large fraction of patients with previously untreated peripheral T-cell lymphomas (PTCLs) - overall and subtype specific results of a phase II study from the Nordic Lymphoma Group. 14th Congress of the EHA. 2009. This is an interim analysis of a big, multicenter, prospective study on dose-dense induction with CHOEP-14 followed by ASCT in patients with PTCL. Among the 160 patients included were 21 patients with EATL.
    • (2009) 14th Congress of the EHA
    • D'Amore, F.1    Lauritzen, G.2    Jantunen, E.3
  • 27
    • 79960117770 scopus 로고    scopus 로고
    • Enteropathy-associated T-cell lymphoma: Clinical and histological findings from the International Peripheral T-Cell Lymphoma Project
    • 21566094 10.1182/blood-2011-02-335216 1:CAS:528:DC%2BC3MXptlSntLw%3D The International T-cell Lymphoma Project (ITLP) studied a cohort of 62 EATL patients among 1,153 patients with PTCL from 22 centers worldwide, diagnosed between 1990 and 2002. Clinical correlation and survival analyses were performed
    • J Delabie H Holte JM Vose, et al. 2011 Enteropathy-associated T-cell lymphoma: clinical and histological findings from the International Peripheral T-Cell Lymphoma Project Blood 118 148 155 21566094 10.1182/blood-2011-02-335216 1:CAS:528:DC%2BC3MXptlSntLw%3D The International T-cell Lymphoma Project (ITLP) studied a cohort of 62 EATL patients among 1,153 patients with PTCL from 22 centers worldwide, diagnosed between 1990 and 2002. Clinical correlation and survival analyses were performed
    • (2011) Blood , vol.118 , pp. 148-155
    • Delabie, J.1    Holte, H.2    Vose, J.M.3
  • 28
    • 0031775883 scopus 로고    scopus 로고
    • Enteropathy-associated T cell lymphoma with brain involvement
    • DOI 10.1097/00004836-199806000-00026
    • EL Berman NP Zauber RR Rickert TC Diss PG Isaacson 1998 Enteropathy-associated T cell lymphoma with brain involvement J Clin Gastroenterol 26 337 341 9649024 10.1097/00004836-199806000-00026 1:STN:280:DyaK1czhtFemug%3D%3D (Pubitemid 28272517)
    • (1998) Journal of Clinical Gastroenterology , vol.26 , Issue.4 , pp. 337-341
    • Berman, E.L.1    Zauber, N.P.2    Rickert, R.R.3    Diss, T.C.4    Isaacson, P.G.5
  • 29
    • 0030793261 scopus 로고    scopus 로고
    • Enteropathy associated T cell lymphoma presenting as an isolated CNS lymphoma three years after diagnosis of coeliac disease: T cell receptor polymerase chain reaction studies failed to show the original enteropathy to be a clonal disorder
    • 9245937 10.1136/gut.40.6.801 1:STN:280:DyaK2szovVOjtg%3D%3D
    • AN Tutt M Brada SA Sampson 1997 Enteropathy associated T cell lymphoma presenting as an isolated CNS lymphoma three years after diagnosis of coeliac disease: T cell receptor polymerase chain reaction studies failed to show the original enteropathy to be a clonal disorder Gut. 40 801 9245937 10.1136/gut.40.6.801 1:STN:280:DyaK2szovVOjtg%3D%3D
    • (1997) Gut. , vol.40 , pp. 801
    • Tutt, A.N.1    Brada, M.2    Sampson, S.A.3
  • 30
    • 0042130357 scopus 로고    scopus 로고
    • Intestinal non-Hodgkin's lymphoma: A multicenter prospective clinical study from the German Study Group on intestinal non-Hodgkin's lymphoma
    • DOI 10.1200/JCO.2003.06.026
    • S Daum R Ullrich W Heise, et al. 2003 Intestinal non-Hodgkin's lymphoma: a multicenter prospective clinical study from the German study group on intestinal non-Hodgkin's Lymphoma J Clin Oncol. 21 2740 2746 12860953 10.1200/JCO.2003.06.026 (Pubitemid 46606320)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.14 , pp. 2740-2746
    • Daum, S.1    Ullrich, R.2    Heise, W.3    Dederke, B.4    Foss, H.-D.5    Stein, H.6    Thiel, E.7    Zeitz, M.8    Riecken, E.-O.9
  • 32
    • 70349310325 scopus 로고    scopus 로고
    • Phase II-I-II study of two different doses and schedules of pralatrexate, a high-affinity substrate for the reduced folate carrier, in patients with relapsed or refractory lymphoma reveals marked activity in T-cell malignancies
    • 19652067 10.1200/JCO.2008.20.8470
    • OA O'Connor S Horwitz P Hamlin, et al. 2009 Phase II-I-II study of two different doses and schedules of pralatrexate, a high-affinity substrate for the reduced folate carrier, in patients with relapsed or refractory lymphoma reveals marked activity in T-cell malignancies J Clin Oncol. 27 4357 4364 19652067 10.1200/JCO.2008.20.8470
    • (2009) J Clin Oncol. , vol.27 , pp. 4357-4364
    • O'Connor, O.A.1    Horwitz, S.2    Hamlin, P.3
  • 33
    • 67449130517 scopus 로고    scopus 로고
    • Results of a phase 2 NCI multicentre study of romidepsin in patients with relapsed peripheral T-cell lymphoma (PTCL)
    • R Piekarz J Wright R Frye SL Allen M Craig L Geskin 2008 Results of a phase 2 NCI multicentre study of romidepsin in patients with relapsed peripheral T-cell lymphoma (PTCL) Blood (ASH Annual Meeting Abstracts) 112 1567
    • (2008) Blood (ASH Annual Meeting Abstracts) , vol.112 , pp. 1567
    • Piekarz, R.1    Wright, J.2    Frye, R.3    Allen, S.L.4    Craig, M.5    Geskin, L.6
  • 35
    • 37049003122 scopus 로고    scopus 로고
    • Forodesine IV (Bcx 1777) is clinically active in relapsed/refractory T-cell leukemia: Results of a phase II study (interim report)
    • RR Furman L Gore F Ravandi D Hoelzer 2006 Forodesine IV (Bcx 1777) is clinically active in relapsed/refractory T-cell leukemia: Results of a phase II study (interim report) Blood (ASH Annual Meeting Abstracts) 108 1851
    • (2006) Blood (ASH Annual Meeting Abstracts) , vol.108 , pp. 1851
    • Furman, R.R.1    Gore, L.2    Ravandi, F.3    Hoelzer, D.4
  • 36
    • 0032435867 scopus 로고    scopus 로고
    • Therapy with gemcitabine in pretreated peripheral T-cell lymphoma patients
    • DOI 10.1023/A:1008409601731
    • PL Zinzani M Magagnoli M Bendandi, et al. 1998 Therapy with gemcitabine in pretreated peripheral T-cell lymphoma patients Ann Oncol. 9 1351 1353 9932168 10.1023/A:1008409601731 1:STN:280:DyaK1M7jtV2lsg%3D%3D (Pubitemid 29045577)
    • (1998) Annals of Oncology , vol.9 , Issue.12 , pp. 1351-1353
    • Zinzani, P.L.1
  • 37
    • 0035014189 scopus 로고    scopus 로고
    • Treatment of refractory T-cell malignancies using gemcitabine
    • DOI 10.1046/j.1365-2141.2001.02743.x
    • S Sallah JY Wan NP Nguyen 2001 Treatment of refractory T-cell malignancies using gemcitabine Br J Haematol. 113 185 187 11328299 10.1046/j.1365-2141.2001.02743.x 1:CAS:528:DC%2BD3MXkt1SjsL0%3D (Pubitemid 32423320)
    • (2001) British Journal of Haematology , vol.113 , Issue.1 , pp. 185-187
    • Sallah, S.1    Wan, J.Y.2    Nguyen, N.P.3
  • 38
    • 58149347800 scopus 로고    scopus 로고
    • Autologous stem-cell transplantation as first-line therapy in peripheral T-cell lymphomas: Results of a prospective multicenter study
    • 19029417 10.1200/JCO.2008.17.4870 1:CAS:528:DC%2BD1MXhs1Gnsbo%3D This multicenter, prospective trial assessed the role of ASCT in consolidation in patients with PTCL in first remission after the standard treatment with CHOP
    • P Reimer T Rudiger E Geissinger, et al. 2009 Autologous stem-cell transplantation as first-line therapy in peripheral T-cell lymphomas: results of a prospective multicenter study J Clin Oncol 27 106 113 19029417 10.1200/JCO.2008.17.4870 1:CAS:528:DC%2BD1MXhs1Gnsbo%3D This multicenter, prospective trial assessed the role of ASCT in consolidation in patients with PTCL in first remission after the standard treatment with CHOP
    • (2009) J Clin Oncol , vol.27 , pp. 106-113
    • Reimer, P.1    Rudiger, T.2    Geissinger, E.3
  • 40
    • 0036745480 scopus 로고    scopus 로고
    • CD56 positive intestinal T-cell lymphoma: Treatment with high dose chemotherapy and autologous peripheral blood stem cell transplantation
    • 12322803 10.2169/internalmedicine.41.734
    • M Okuda J Nomura H Tateno J Kameoka T Sasaki 2002 CD56 positive intestinal T-cell lymphoma: treatment with high dose chemotherapy and autologous peripheral blood stem cell transplantation Intern Med. 41 734 737 12322803 10.2169/internalmedicine.41.734
    • (2002) Intern Med. , vol.41 , pp. 734-737
    • Okuda, M.1    Nomura, J.2    Tateno, H.3    Kameoka, J.4    Sasaki, T.5
  • 41
    • 33746455861 scopus 로고    scopus 로고
    • Successful treatment of enteropathy-associated T cell lymphoma with autologous stem cell transplant
    • DOI 10.1007/s10620-006-8013-z
    • C Rongey I Micallef T Smyrk J Murray 2006 Successful treatment of enteropathy-associated T cell lymphoma with autologous stem cell transplant Dig Dis Sci. 51 1082 1086 16865575 10.1007/s10620-006-8013-z (Pubitemid 44127059)
    • (2006) Digestive Diseases and Sciences , vol.51 , Issue.6 , pp. 1082-1086
    • Rongey, C.1    Micallef, I.2    Smyrk, T.3    Murray, J.4
  • 43
    • 70849099193 scopus 로고    scopus 로고
    • High-dose CHOP plus etoposide (MegaCHOEP) in T-cell lymphoma: A comparative analysis of patients treated within trials of the German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL)
    • 19570965 10.1093/annonc/mdp211 1:STN:280:DC%2BD1MjntFOjtA%3D%3D
    • M Nickelsen M Ziepert S Zeynalova, et al. 2009 High-dose CHOP plus etoposide (MegaCHOEP) in T-cell lymphoma: a comparative analysis of patients treated within trials of the German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL) Ann Oncol. 20 1977 1984 19570965 10.1093/annonc/mdp211 1:STN:280:DC%2BD1MjntFOjtA%3D%3D
    • (2009) Ann Oncol. , vol.20 , pp. 1977-1984
    • Nickelsen, M.1    Ziepert, M.2    Zeynalova, S.3
  • 45
    • 0023911799 scopus 로고
    • Successful treatment of atypical sprue in an infant with cyclosporine
    • 3371614 1:STN:280:DyaL1c3isF2itg%3D%3D
    • EF Bernstein PF Whitington 1988 Successful treatment of atypical sprue in an infant with cyclosporine Gastroenterology. 95 199 204 3371614 1:STN:280:DyaL1c3isF2itg%3D%3D
    • (1988) Gastroenterology. , vol.95 , pp. 199-204
    • Bernstein, E.F.1    Whitington, P.F.2
  • 46
    • 0034040403 scopus 로고    scopus 로고
    • Cyclosporin in the treatment of adults with refractory coeliac disease - An open pilot study
    • DOI 10.1046/j.1365-2036.2000.00718.x
    • PJ Wahab JB Crusius JW Meijer JJ Uil CJ Mulder 2000 Cyclosporin in the treatment of adults with refractory coeliac disease-an open pilot study Aliment Pharmacol Ther. 14 767 774 10848661 10.1046/j.1365-2036.2000.00718.x 1:CAS:528:DC%2BD3cXltFSltLo%3D (Pubitemid 30352744)
    • (2000) Alimentary Pharmacology and Therapeutics , vol.14 , Issue.6 , pp. 767-774
    • Wahab, P.J.1    Crusius, J.B.A.2    Meijer, J.W.R.3    Uil, J.J.4    Mulder, C.J.J.5
  • 47
    • 0034759899 scopus 로고    scopus 로고
    • A pilot study of recombinant human interleukin-10 in adults with refractory coeliac disease
    • DOI 10.1097/00042737-200110000-00010
    • CJ Mulder PJ Wahab JW Meijer E Metselaar 2001 A pilot study of recombinant human interleukin-10 in adults with refractory coeliac disease Eur J Gastroenterol Hepatol. 13 1183 1188 11711774 10.1097/00042737-200110000-00010 1:CAS:528:DC%2BD3MXosFCgs74%3D (Pubitemid 33015884)
    • (2001) European Journal of Gastroenterology and Hepatology , vol.13 , Issue.10 , pp. 1183-1188
    • Mulder, C.J.J.1    Wahab, P.J.2    Meijer, J.W.R.3    Metselaar, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.