Association between polymorphisms of the cytokine and cytokine receptor genes and immune response to hepatitis B vaccination in a Chinese Han population

Journal of Medical Virology

Volumn 84, Issue 1, 2012, Pages 26-33

  Pan, Liping ^a   Zhang, Wei ^b   Liang, Zhenglun ^c   Wu, Xiaopan ^a   Zhu, Xilin ^a   Li, Jingyun ^a   Li, Tianjie ^a   Wang, Li ^a   Li, Hui ^a   Liu, Ying ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b Beijing Centers for Diseases Control and Prevention   (China)

^c NATIONAL INSTITUTE FOR THE CONTROL OF PHARMACEUTICAL AND BIOLOGICAL PRODUCTS   (China)

Author keywords

Cytokine gene; Gene gene interaction; Genetic polymorphism; Hepatitis B vaccine

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 4; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; CHINESE; CONTROLLED STUDY; FEMALE; GENE INTERACTION; GENOTYPE; HEPATITIS B; HEPATITIS B VACCINATION; HUMAN; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; SINGLE NUCLEOTIDE POLYMORPHISM; VACCINATION;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CYTOKINES; FEMALE; GENE FREQUENCY; GENOTYPE; HEPATITIS B ANTIBODIES; HEPATITIS B VACCINES; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CYTOKINE;

EID: 81355147313     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.22251     Document Type: Article

References (50)

1. Andrews AL, Bucchieri F, Arima K, Izuhara K, Holgate ST, Davies DE, Holloway JW. 2007. Effect of IL-13 receptor alpha2 levels on the biological activity of IL-13 variant R110Q. J Allergy Clin Immunol 120:91-97.
2. Arima S, Akbar SM, Michitaka K, Horiike N, Nuriya H, Kohara M, Onji M. 2003. Impaired function of antigen-presenting dendritic cells in patients with chronic hepatitis B: Localization of HBV DNA and HBV RNA in blood DC by in situ hybridization. Int J Mol Med 11:169-174.
3. Bocher WO, Herzog-Hauff S, Schlaak J, Meyer zum Buschenfeld KH, Lohr HF. 1999. Kinetics of hepatitis B surface antigen-specific immune responses in acute and chronic hepatitis B or after HBs vaccination: Stimulation of the in vitro antibody response by interferon gamma. Hepatology 29:238-244.
4. Boland GJ, van Bommel T, Rulos-van den Berg A, van den Berg JP, van Loon AM, van Hattum J. 2003. The efficacy of a two-dose hepatitis B vaccination scheme. Adv Exp Med Biol 531:185-190.
5. Chedid MG, Deulofeut H, Yunis DE, Lara-Marquez ML, Salazar M, Deulofeut R, Awdeh Z, Alper CA, Yunis EJ. 1997. Defect in Th1-like cells of nonresponders to hepatitis B vaccine. Hum Immunol 58:42-51.
6. Chen J, Liang Z, Lu F, Fang X, Liu S, Zeng Y, Zhu F, Chen X, Shen T, Li J, Zhuang H. 2010. Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine. Vaccine 29:706-711.
7. Chow YH, Huang WL, Chi WK, Chu YD, Tao MH. 1997. Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2. J Virol 71:169-178.
8. Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. 2010. New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun 11:232-238.
9. Desombere I, Willems A, Leroux-Roels G. 1998. Response to hepatitis B vaccine: Multiple HLA genes are involved. Tissue Antigens 51:593-604.
10. Egea E, Iglesias A, Salazar M, Morimoto C, Kruskall MS, Awdeh Z, Schlossman SF, Alper CA, Yunis EJ. 1991. The cellular basis for lack of antibody response to hepatitis B vaccine in humans. J Exp Med 173:531-538.
11. Godkin A, Davenport M, Hill AV. 2005. Molecular analysis of HLA class II associations with hepatitis B virus clearance and vaccine nonresponsiveness. Hepatology 41:1383-1390.
12. Harber M, Sundstedt A, Wraith D. 2000. The role of cytokines in immunological tolerance: Potential for therapy. Expert Rev Mol Med 2:1-20.
13. Hennig BJ, Fielding K, Broxholme J, Diatta M, Mendy M, Moore C, Pollard AJ, Rayco-Solon P, Sirugo G, van der Sande MA, Waight P, Whittle HC, Zaman SM, Hill AV, Hall AJ. 2008. Host genetic factors and vaccine-induced immunity to hepatitis B virus infection. PLoS ONE 3:e1898.
14. Hirota T, Suzuki Y, Hasegawa K, Obara K, Matsuda A, Akahoshi M, Nakashima K, Cheng L, Takahashi N, Shimizu M, Doi S, Fujita K, Enomoto T, Ebisawa M, Yoshihara S, Nakamura Y, Kishi F, Shirakawa T, Tamari M. 2005. Functional haplotypes of IL-12B are associated with childhood atopic asthma. J Allergy Clin Immunol 116:789-795.
15. Hohler T, Meyer CU, Notghi A, Stradmann-Bellinghausen B, Schneider PM, Starke R, Zepp F, Sanger R, Clemens R, Meyer zum, Buschenfelde KH, Rittner C. 1998. The influence of major histocompatibility complex class II genes and T-cell Vbeta repertoire on response to immunization with HBsAg. Hum Immunol 59:212-218.
16. Hohler T, Reuss E, Evers N, Dietrich E, Rittner C, Freitag CM, Vollmar J, Schneider PM, Fimmers R. 2002. Differential genetic determination of immune responsiveness to hepatitis B surface antigen and to hepatitis A virus: A vaccination study in twins. Lancet 360:991-995.
17. Hohler T, Reuss E, Freitag CM, Schneider PM. 2005. A functional polymorphism in the IL-10 promoter influences the response after vaccination with HBsAg and hepatitis A. Hepatology 42:72-76.
18. Hollinger FB. 1989. Factors influencing the immune response to hepatitis B vaccine, booster dose guidelines, and vaccine protocol recommendations. Am J Med 87:36S-40S.
19. Howe RC, Dhiman N, Ovsyannikova IG, Poland GA. 2005. Induction of CD4 T cell proliferation and in vitro Th1-like cytokine responses to measles virus. Clin Exp Immunol 140:333-342.
20. Jafarzadeh A, Zarei S, Shokri F. 2008. Low dose revaccination induces robust protective anti-HBs antibody response in the majority of healthy non-responder neonates. Vaccine 26:269-276.
21. Kim JJ, Trivedi NN, Nottingham LK, Morrison L, Tsai A, Hu Y, Mahalingam S, Dang K, Ahn L, Doyle NK, Wilson DM, Chattergoon MA, Chalian AA, Boyer JD, Agadjanyan MG, Weiner DB. 1998. Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens. Eur J Immunol 28:1089-1103.
22. Kimman TG, Vandebriel RJ, Hoebee B. 2007. Genetic variation in the response to vaccination. Community Genet 10:201-217.
23. Kobayashi M, Fitz L, Ryan M, Hewick RM, Clark SC, Chan S, Loudon R, Sherman F, Perussia B, Trinchieri G. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 170:827-845.
24. Lango-Warensjo A, Cardell K, Lindblom B. 1998. Haplotypes comprising subtypes of the DQB1*06 allele direct the antibody response after immunisation with hepatitis B surface antigen. Tissue Antigens 52:374-380.
25. Li Y, Ni R, Song W, Shao W, Shrestha S, Ahmad S, Cunningham CK, Flynn PM, Kapogiannis BG, Wilson CM, Tang J. 2009. Clear and independent associations of several HLA-DRB1 alleles with differential antibody responses to hepatitis B vaccination in youth. Hum Genet 126:685-696.
26. Lu FM, Zhuang H. 2009. Prevention of hepatitis B in China: Achievements and challenges. Chin Med J (Engl) 122:2925-2927.
27. Macedo LC, Isolani AP, Visentainer JE, Moliterno RA. 2010. Association of cytokine genetic polymorphisms with the humoral immune response to recombinant vaccine against HBV in infants. J Med Virol 82:929-933.
28. Maddrey W. 2000. Hepatitis B: An important public health issue. J Med Virol 61:362-366.
29. McDermott AB, Zuckerman JN, Sabin CA, Marsh SG, Madrigal JA. 1997. Contribution of human leukocyte antigens to the antibody response to hepatitis B vaccination. Tissue Antigens 50:8-14.
30. McDermott AB, Madrigal JA, Sabin CA, Zuckerman JN, Cohen SB. 1999. The influence of host factors and immunogenetics on lymphocyte responses to Hepagene vaccination. Vaccine 17:1329-1337.
31. Newport MJ, Goetghebuer T, Weiss HA, Whittle H, Siegrist CA, Marchant A. 2004. Genetic regulation of immune responses to vaccines in early life. Genes Immun 5:122-129.
32. Ovsyannikova IG, Reid KC, Jacobson RM, Oberg AL, Klee GG, Poland GA. 2003. Cytokine production patterns and antibody response to measles vaccine. Vaccine 21:3946-3953.
33. Poland GA. 1998. Hepatitis B immunization in health care workers. Dealing with vaccine nonresponse. Am J Prev Med 15:73-77.
34. Poland GA, Ovsyannikova IG, Jacobson RM, Smith DI. 2007. Heterogeneity in vaccine immune response: The role of immunogenetics and the emerging field of vaccinomics. Clin Pharmacol Ther 82:653-664.
35. Shi YY, He L. 2005. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 15:97-98.
36. Sin JI, Kim JJ, Arnold RL, Shroff KE, McCallus D, Pachuk C, McElhiney SP, Wolf MW, Pompa-de Bruin SJ, Higgins TJ, Ciccarelli RB, Weiner DB. 1999. IL-12 gene as a DNA vaccine adjuvant in a herpes mouse model: IL-12 enhances Th1-type CD4+ T cell-mediated protective immunity against herpes simplex virus-2 challenge. J Immunol 162:2912-2921.
37. Smith AJ, Humphries SE. 2009. Cytokine and cytokine receptor gene polymorphisms and their functionality. Cytokine Growth Factor Rev 20:43-59.
38. Suarez A, Castro P, Alonso R, Mozo L, Gutierrez C. 2003. Interindividual variations in constitutive interleukin-10 messenger RNA and protein levels and their association with genetic polymorphisms. Transplantation 75:711-717.
39. Trinchieri G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3:133-146.
40. Velu V, Saravanan S, Nandakumar S, Shankar EM, Vengatesan A, Jadhav SS, Kulkarni PS, Thyagarajan SP. 2008. Relationship between T-lymphocyte cytokine levels and sero-response to hepatitis B vaccines. World J Gastroenterol 14:3534-3540.
41. Vingerhoets J, Vanham G, Kestens L, Penne G, Leroux-Roels G, Gigase P. 1994. Deficient T-cell responses in non-responders to hepatitis B vaccination: Absence of TH1 cytokine production. Immunol Lett 39:163-168.
42. Vingerhoets J, Goilav C, Vanham G, Kestens L, Muylle L, Kegels E, Van Hoof J, Piot P, Gigase P. 1995. Non-response to a recombinant pre-S2-containing hepatitis B vaccine: Association with the HLA-system. Ann Soc Belg Med Trop 75:125-129.
43. Wang C, Tang J, Song W, Lobashevsky E, Wilson CM, Kaslow RA. 2004. HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination. Hepatology 39:978-988.
44. Weissman JY, Tsuchiyose MM, Tong MJ, Co R, Chin K, Ettenger RB. 1988. Lack of response to recombinant hepatitis B vaccine in nonresponders to the plasma vaccine. JAMA 260:1734-1738.
45. Yucesoy B, Sleijffers A, Kashon M, Garssen J, de Gruijl FR, Boland GJ, van Hattum J, Simeonova PP, Luster MI, van Loveren H. 2002. IL-1beta gene polymorphisms influence hepatitis B vaccination. Vaccine 20:3193-3196.
46. Yucesoy B, Johnson VJ, Fluharty K, Kashon ML, Slaven JE, Wilson NW, Weissman DN, Biagini RE, Germolec DR, Luster MI. 2009. Influence of cytokine gene variations on immunization to childhood vaccines. Vaccine 27:6991-6997.
47. Zhuang GH, Yan H, Wang XL, Hwang LY, Wu Q, Wang LR, Gao HY. 2006. Hepatitis B revaccination in healthy non-responder Chinese children: Five-year follow-up of immune response and immunologic memory. Vaccine 24:2186-2192.
48. Zuckerman JN. 1996. Nonresponse to hepatitis B vaccines and the kinetics of anti-HBs production. J Med Virol 50:283-288.
49. Zuckerman JN. 2006. Protective efficacy, immunotherapeutic potential, and safety of hepatitis B vaccines. J Med Virol 78:169-177.
50. Zuckerman JN, Zuckerman AJ. 2000. Current topics in hepatitis B. J Infect 41:130-136.