Opioid patient controlled analgesia use during the initial experience with the IMPROVE PCA trial: A phase III analgesic trial for hospitalized sickle cell patients with painful episodes

American Journal of Hematology

Volumn 86, Issue 12, 2011, Pages

  Dampier, Carlton D ^a   Smith, Wally R ^b   Kim, Hae Young ^c   Wager, Carrie Greene ^c   Bell, Margaret C ^c   Minniti, Caterina P ^d   Keefer, Jeffrey ^e   Hsu, Lewis ^f   Krishnamurti, Lakshmanan ^g   Mack, A Kyle ^h   Mcclish, Donna ^b   Mckinlay, Sonja M ^c   Miller, Scott T ^c   Osunkwo, Ifeyinwa ^a   Seaman, Phillip ^e   Telen, Marilyn J ⁱ   Weiner, Debra L ^j  

^a CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c NEW ENGLAND RESEARCH INSTITUTES   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^g CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^h CHILDREN'S MEMORIAL HOSPITAL   (United States)

ⁱ DUKE UNIVERSITY MEDICAL CENTER   (United States)

^j BOSTON CHILDREN S HOSPITAL   (United States)

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Author keywords

[No Author keywords available]

Indexed keywords

HYDROMORPHONE; MORPHINE;

ADOLESCENT; ADULT; ARTICLE; BLOOD VESSEL OCCLUSION; CHILD; CONTROLLED STUDY; DRUG INFUSION; FEMALE; HOSPITAL PATIENT; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PAIN; PATIENT CONTROLLED ANALGESIA; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; SCHOOL CHILD; SCORING SYSTEM; SICKLE CELL ANEMIA; VISUAL ANALOG SCALE;

ADOLESCENT; ADULT; AGE FACTORS; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; CHILD; DOSE-RESPONSE RELATIONSHIP, DRUG; EARLY TERMINATION OF CLINICAL TRIALS; FEMALE; HEMOGLOBIN SC DISEASE; HUMANS; HYDROMORPHONE; INFUSIONS, INTRAVENOUS; LENGTH OF STAY; MALE; MIDDLE AGED; MORPHINE; PAIN; VASCULAR DISEASES; YOUNG ADULT;

EID: 81355146617     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.22176     Document Type: Article

References (19)

1. Powars DR, Chan LS, Hiti A, et al. Outcome of sickle cell anemia: A 4-decade observational study of 1056 patients. Medicine (Baltimore) 2005; 84: 363-376.
2. Conran N, Franco-Penteado CF, Costa FF. Newer aspects of the pathophysiology of sickle cell disease vaso-occlusion. Hemoglobin 2009; 33: 1-16.
3. Rees DC, Olujohungbe AD, Parker NE, et al. Guidelines for the management of the acute painful crisis in sickle cell disease. Br J Haematol 2003; 120: 744-752.
4. Benjamin LJ, Dampier CD, Jacox A, et al. Guideline for the management of acute and chronic pain in sickle-cell disease. Am Pain Soc 1999.
5. Trentadue NO, Kachoyeanos MK, Lea G. A comparison of two regimens of patient-controlled analgesia for children with sickle cell disease. J Pediatr Nurs 1998; 13: 15-19.
6. van Beers EJ, van Tuijn CF, Nieuwkerk PT, et al. Patient-controlled analgesia versus continuous infusion of morphine during vaso-occlusive crisis in sickle cell disease, a randomized controlled trial. Am J Hematol 2007; 82: 955-960.
7. Jacob E, Hockenberry M, Mueller BU, et al. Analgesic response to morphine in children with sickle cell disease: A pilot study. J Pain Manag 2008; 2: 179-190.
8. George JA, Lin EE, Hanna MN, et al. The effect of intravenous opioid patient-controlled analgesia with and without background infusion on respiratory depression: A meta-analysis. J Opioid Manag 2010; 6: 47-54.
9. Walder B, Schafer M, Henzi I, et al. Efficacy and safety of patient-controlled opioid analgesia for acute postoperative pain. A quantitative systematic review. Acta Anaesthesiol Scand 2001; 45: 795-804.
10. McNeely JK, Trentadue NC. Comparison of patient-controlled analgesia with and without nighttime morphine infusion following lower extremity surgery in children. J Pain Symptom Manage 1997; 13: 268-273.
11. Apfelbaum JL, Gan TJ, Zhao S, et al. Reliability and validity of the perioperative opioid-related symptom distress scale. Anesth Analg 2004; 99: 699-709.
12. Gregorian RSJr, Gasik A, Kwong WJ, et al. Importance of side effects in opioid treatment: A trade-off analysis with patients and physicians. J Pain 2010; 11: 1095-1108.
13. Doyle E, Robinson D, Morton NS. Comparison of patient-controlled analgesia with and without a background infusion after lower abdominal surgery in children. Br J Anaesth 1993; 71: 670-673.
14. Lopez BL, Flenders P, Davis-Moon L, et al. Clinically significant differences in the visual analog pain scale in acute vasoocclusive sickle cell crisis. Hemoglobin 2007; 31: 427-432.
15. Gossop M. The development of a short opiate withdrawal scale (SOWS). Addict Behav 1990; 15: 487-490.
16. R Development Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2010.
17. Sarkar D. Lattice: Multivariate Data Visualization with R. New York: Springer; 2008.
18. Scheipl F. amer: Additive mixed models with lme4, R package version 0.6.7, 2010. Available at.
19. Bates D, Maechler M. lme4: Linear Mixed-Effects Models Using S4 Classes. R Package Version 0.999375-37., 2010. Available at.