ALLELE;
DRUG ABSORPTION;
DRUG ACTIVATION;
DRUG EFFECT;
DRUG EFFICACY;
DRUG METABOLISM;
ENZYME ACTIVITY;
GENETIC POLYMORPHISM;
HUMAN;
LOADING DRUG DOSE;
PHARMACOGENOMICS;
PHENOTYPE;
PRIORITY JOURNAL;
REVIEW;
THROMBOCYTE AGGREGATION INHIBITION;
Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients erspectives undergoing percutaneous coronary intervention: The PCI-CURE study
CURE Investigators Clopidogrel in Unstable angina to prevent Recurrent Events trial
CURE Investigators. Clopidogrel in Unstable angina to prevent Recurrent Events trial. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients erspectives undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet 358, 527-533 (2001).
Genetic determinants of response to clopidogrel and cardiovascular events
French Registry of ST-Elevation and Non-STElevation Myocardial Infarction (FAST-MI) Investigators
French Registry of ST-Elevation and Non-STElevation Myocardial Infarction (FAST-MI) Investigators. Genetic determinants of response to clopidogrel and cardiovascular events. N. Engl. J. Med. 360, 363-375 (2009).
Consensus and future directions on the definition of high on-treatment platelet reactivity to ADP
Working Group on High On-Treatment Platelet Reactivity
Bonello, L. et al.; Working Group on High On-Treatment Platelet Reactivity. Consensus and future directions on the definition of high on-treatment platelet reactivity to ADP. J. Am. Coll. Cardiol. 56, 919-933 (2010).
Impact of cytochrome P450 2C19 loss-of-function polymorphism and of major demographic characteristics on residual platelet function after loading and maintenance treatment with clopidogrel in patients undergoing elective coronary stent placement
Hochholzer, W. et al. Impact of cytochrome P450 2C19 loss-of-function polymorphism and of major demographic characteristics on residual platelet function after loading and maintenance treatment with clopidogrel in patients undergoing elective coronary stent placement. J. Am. Coll. Cardiol. 55, 2427-2434 (2010).
Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction
Simon, T. et al. Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction. Clin. Pharmacol. Ther. 90, 561-567 (2011).
Clopidogrel loading dose adjustment according to platelet reactivity monitoring in patients carrying the 2C19*2 loss of function polymorphism
Bonello, L. et al. Clopidogrel loading dose adjustment according to platelet reactivity monitoring in patients carrying the 2C19*2 loss of function polymorphism. J. Am. Coll. Cardiol. 56, 1630-1636 (2010).
Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: A pharmacogenetic analysis
Mega, J.L. et al. Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis. Lancet 376, 1312-1319 (2010).
High on-treatment platelet reactivity after prasugrel loading dose and cardiovascular events after percutaneous coronary intervention in coronary syndromes
Bonello, L. et al. High on-treatment platelet reactivity after prasugrel loading dose and cardiovascular events after percutaneous coronary intervention in coronary syndromes. J. Am. Coll. Cardiol. 58, 467-473 (2011).