Efficient synthesis of 2-(2-aminophenyl)-2,3-dihydropyridin-4(1H)-ones based on a cyclization/ring cleavage procedure

Helvetica Chimica Acta

Volumn 94, Issue 11, 2011, Pages 2045-2053

  Karapetyan, Vahuni ^a,b   Mkrtchyan, Satenik ^a,b   Karapetyan, Gnuni ^a   Villinger, Alexander ^a   Saghiyan, Ashot ^b,c   Ghochikyan, Tariel V ^b   Langer, Peter ^a,d  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b YEREVAN STATE UNIVERSITY   (Armenia)

^c CJSC Scientific Research Institute of Biotechnology   (Armenia)

^d LEIBNIZ INSTITUT FÜR KATALYSE E V AN DER UNIVERSITÄT ROSTOCK   (Germany)

Author keywords

Pyridin 4(1H) ones; Quinazolines; Silyl enol ethers; X Ray crystallography

Indexed keywords

CYCLIZATIONS; DEPROTECTION; EFFICIENT SYNTHESIS; ONE POT; PYRIDIN-4(1H)-ONES; QUINAZOLINES; SILYL ENOL ETHERS;

ETHERS; ORGANIC COMPOUNDS;

X RAY CRYSTALLOGRAPHY;

1 METHYLETHYL 6 (2 AMINOPHENYL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; 1,11 DIBENZYL 3 (1 METHYLETHYL) 5,6 DIHYDRO 4 HYDROXY 2,6 EPIMINO 1 BENZAZOCINE 1,3,11(2H) TRICARBOXYLATE; 1,11 DIBENZYL 3 (2 METHOXYETHYL) 5,6 DIHYDRO 4 HYDROXY 2,6 EPIMINO 1 BENZAZOCINE 1,3,11(2H) TRICARBOXYLATE; 1,11 DIBENZYL 3 (2 METHYLPROPYL) 5,6 DIHYDRO 4 HYDROXY 2,6 EPIMINO 1 BENZAZOCINE 1,3,11(2H) TRICARBOXYLATE; 1,11 DIBENZYL 3 ETHYL 5,6 DIHYDRO 4 HYDROXY 2,6 EPIMINO 1 BENZAZOCINE 1,3,11(2H) TRICARBOXYLATE; 1,11 DIBENZYL 3 ETHYL 5,6 DIHYDRO 4 HYDROXY 8,9 DIMETHYL 2,6 EPIMINO 1 BENZAZOCINE 1,3,11(2H) TRICARBOXYLATE; 1,11 DIBENZYL 3 METHYL 5,6 DIHYDRO 4 HYDROXY 2,6 EPIMINO 1 BENZAZOCINE 1,3,11(2H) TRICARBOXYLATE; 1,11 DIBENZYL 3 METHYL 5,6 DIHYDRO 4 HYDROXY 8,9 DIMETHYL 2,6 EPIMINO 1 BENZAZOCINE 1,3,11(2H) TRICARBOXYLATE; 1,12 DIBENZYL 3 ETHYL 2,5,6,8,9,10 HEXAHYDRO 4 HYDROXY 1H 2,6 EPIMINOINDEN[5,6 B]AZOCINE 1,3,12 TRICARBOXYLATE; 1,12 DIBENZYL 3 METHYL 2,5,6,8,9,10 HEXAHYDRO 4 HYDROXY 1H 2,6 EPIMINOINDEN[5,6 B]AZOCINE 1,3,12 TRICARBOXYLATE; 2 METHOXYETHYL 6 (2 AMINOPHENYL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; 2 METHYLPROPYL 6 (2 AMINOPHENYL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; 5 ACETYL 2 (2 AMINOPHENYL) 2,3 DIHYDROPYRIDIN 4(1H) ONE; ALKENE DERIVATIVE; DIHYDROPYRIDINE DERIVATIVE; ETHYL 6 (2 AMINO 4,5 DIMETHYLPHENYL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; ETHYL 6 (2 AMINOPHENYL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; ETHYL 6 (6 AMINO 2,3 DIHYDRO 1H INDEN 5 YL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; METHYL 6 (2 AMINO 4,5 DIMETHYLPHENYL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; METHYL 6 (2 AMINOPHENYL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; METHYL 6 (6 AMINO 2,3 DIHYDRO 1H INDEN 5 YL) 1,4,5,6 TETRAHYDRO 4 OXOPYRIDINE 3 CARBOXYLATE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DEPROTECTION REACTION; DRUG SYNTHESIS; HYDROGENATION; ONE POT SYNTHESIS; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 81255214571     PISSN: 0018019X     EISSN: 15222675     Source Type: Journal    
DOI: 10.1002/hlca.201100130     Document Type: Article

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