Binding energy and catalysis by d -xylose isomerase: Kinetic, product, and X-ray Crystallographic analysis of enzyme-catalyzed isomerization of (R)-glyceraldehyde

Biochemistry

Volumn 50, Issue 46, 2011, Pages 10170-10181

  Toteva, Maria M ^a   Silvaggi, Nicholas R ^b   Allen, Karen N ^c   Richard, John P ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^c Boston University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION BARRIERS; ACTIVE SITE RESIDUES; COFACTORS; CONFORMATIONAL CHANGE; D-XYLOSE; DEPROTONATION REACTION; DIHYDROXYACETONE; HYDRIDE TRANSFERS; INTRINSIC BINDING; ISOMERASES; ISOMERIZATION REACTION; LIGAND BINDING; SOAKING CRYSTALS; TRIOSEPHOSPHATE ISOMERASE; X RAY CRYSTAL STRUCTURES; X-RAY CRYSTALLOGRAPHIC ANALYSIS; XYLOSE ISOMERASE;

BINDING ENERGY; CATALYSIS; COMPLEXATION; CRYSTAL STRUCTURE; DEUTERIUM; ETHYLENE; ETHYLENE GLYCOL; GLUCOSE; HYDRATES; HYDRATION; ISOMERIZATION; ISOMERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUBSTRATES; X RAY CRYSTALLOGRAPHY;

XYLOSE;

ALDEHYDE; CARBON; DEUTERIUM; ETHYLENE GLYCOL; GLYCERALDEHYDE; HEXOSE; PENTOSE; XYLOSE ISOMERASE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONFORMATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ISOMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; X RAY CRYSTALLOGRAPHY;

ALDOSE-KETOSE ISOMERASES; CRYSTALLOGRAPHY, X-RAY; GLYCERALDEHYDE; ISOMERISM; KINETICS; MODELS, MOLECULAR; PROTEIN BINDING; STREPTOMYCES; THERMODYNAMICS; XYLOSE;

EID: 81255195348     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201378c     Document Type: Article

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