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Volumn 87, Issue 6, 2011, Pages 503-509

Sirolimus and tacrolimus as immune prophylaxis compared to cyclosporine with or without methotrexate in patients undergoing allogeneic haematopoietic stem cell transplantation for non-malignant disorders

Author keywords

Allogeneic haematopoietic stem cell transplantation; Cyclosporine; Epstein Barr virus lymphoma; Inborn error of metabolism; Prograf; Rapamune

Indexed keywords

BILIRUBIN; CD19 ANTIGEN; CD3 ANTIGEN; CD33 ANTIGEN; CHOLESTEROL; CREATININE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; FLUDARABINE; METHOTREXATE; RAPAMYCIN; TACROLIMUS;

EID: 81255184992     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2011.01685.x     Document Type: Article
Times cited : (21)

References (35)
  • 1
    • 0027525864 scopus 로고
    • Methotrexate, cyclosporine, or both to prevent graft-versus-host disease after HLA-identical sibling bone marrow transplants for early leukemia?
    • Ringden O, Horowitz MM, Sondel P, et al. Methotrexate, cyclosporine, or both to prevent graft-versus-host disease after HLA-identical sibling bone marrow transplants for early leukemia? Blood 1993;81:1094-101.
    • (1993) Blood , vol.81 , pp. 1094-1101
    • Ringden, O.1    Horowitz, M.M.2    Sondel, P.3
  • 2
    • 0024510510 scopus 로고
    • Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial
    • Storb R, Deeg HJ, Pepe M, et al. Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial. Blood 1989;73:1729-34.
    • (1989) Blood , vol.73 , pp. 1729-1734
    • Storb, R.1    Deeg, H.J.2    Pepe, M.3
  • 3
    • 0034909687 scopus 로고    scopus 로고
    • Phase III study comparing tacrolimus (FK506) with cyclosporine for graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation
    • Hiraoka A, Ohashi Y, Okamoto S, Moriyama Y, Nagao T, Kodera Y, Kanamaru A, Dohy H, Masaoka T. Phase III study comparing tacrolimus (FK506) with cyclosporine for graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation. Bone Marrow Transplant 2001;28:181-5.
    • (2001) Bone Marrow Transplant , vol.28 , pp. 181-185
    • Hiraoka, A.1    Ohashi, Y.2    Okamoto, S.3    Moriyama, Y.4    Nagao, T.5    Kodera, Y.6    Kanamaru, A.7    Dohy, H.8    Masaoka, T.9
  • 4
    • 0034665674 scopus 로고    scopus 로고
    • Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors
    • Nash RA, Antin JH, Karanes C, et al. Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors. Blood 2000;96:2062-8.
    • (2000) Blood , vol.96 , pp. 2062-2068
    • Nash, R.A.1    Antin, J.H.2    Karanes, C.3
  • 5
    • 0032188990 scopus 로고    scopus 로고
    • Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation
    • Ratanatharathorn V, Nash RA, Przepiorka D, et al. Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation. Blood 1998;92:2303-14.
    • (1998) Blood , vol.92 , pp. 2303-2314
    • Ratanatharathorn, V.1    Nash, R.A.2    Przepiorka, D.3
  • 6
    • 0345161813 scopus 로고    scopus 로고
    • Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group
    • Groth CG, Backman L, Morales JM, et al. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group. Transplantation 1999;67:1036-42.
    • (1999) Transplantation , vol.67 , pp. 1036-1042
    • Groth, C.G.1    Backman, L.2    Morales, J.M.3
  • 7
    • 0037775561 scopus 로고    scopus 로고
    • A prospective randomized multicenter study of tacrolimus in combination with sirolimus in renal-transplant recipients
    • van Hooff JP, Squifflet JP, Wlodarczyk Z, Vanrenterghem Y, Paczek L. A prospective randomized multicenter study of tacrolimus in combination with sirolimus in renal-transplant recipients. Transplantation 2003;75:1934-9.
    • (2003) Transplantation , vol.75 , pp. 1934-1939
    • van Hooff, J.P.1    Squifflet, J.P.2    Wlodarczyk, Z.3    Vanrenterghem, Y.4    Paczek, L.5
  • 8
    • 21244458013 scopus 로고    scopus 로고
    • Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site
    • Ali SM, Sabatini DM. Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005;280:19445-8.
    • (2005) J Biol Chem , vol.280 , pp. 19445-19448
    • Ali, S.M.1    Sabatini, D.M.2
  • 9
    • 0032105481 scopus 로고    scopus 로고
    • Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression
    • Sehgal SN. Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin Biochem 1998;31:335-40.
    • (1998) Clin Biochem , vol.31 , pp. 335-340
    • Sehgal, S.N.1
  • 10
    • 0036682957 scopus 로고    scopus 로고
    • Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells
    • Hackstein H, Taner T, Logar AJ, Thomson AW. Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells. Blood 2002;100:1084-7.
    • (2002) Blood , vol.100 , pp. 1084-1087
    • Hackstein, H.1    Taner, T.2    Logar, A.J.3    Thomson, A.W.4
  • 11
    • 0038036797 scopus 로고    scopus 로고
    • Rapamycin inhibits IL-4 - induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
    • Hackstein H, Taner T, Zahorchak AF, Morelli AE, Logar AJ, Gessner A, Thomson AW. Rapamycin inhibits IL-4 - induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. Blood 2003;101:4457-63.
    • (2003) Blood , vol.101 , pp. 4457-4463
    • Hackstein, H.1    Taner, T.2    Zahorchak, A.F.3    Morelli, A.E.4    Logar, A.J.5    Gessner, A.6    Thomson, A.W.7
  • 12
    • 0037441902 scopus 로고    scopus 로고
    • Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression
    • Woltman AM, van der Kooij SW, Coffer PJ, Offringa R, Daha MR, van Kooten C. Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. Blood 2003;101:1439-45.
    • (2003) Blood , vol.101 , pp. 1439-1445
    • Woltman, A.M.1    van der Kooij, S.W.2    Coffer, P.J.3    Offringa, R.4    Daha, M.R.5    van Kooten, C.6
  • 13
    • 10744225688 scopus 로고    scopus 로고
    • A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1year
    • Ciancio G, Burke GW, Gaynor JJ, Mattiazzi A, Roth D, Kupin W, Nicolas M, Ruiz P, Rosen A, Miller J. A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1year. Transplantation 2004;77:252-8.
    • (2004) Transplantation , vol.77 , pp. 252-258
    • Ciancio, G.1    Burke, G.W.2    Gaynor, J.J.3    Mattiazzi, A.4    Roth, D.5    Kupin, W.6    Nicolas, M.7    Ruiz, P.8    Rosen, A.9    Miller, J.10
  • 14
    • 0037910271 scopus 로고    scopus 로고
    • Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis
    • Koenen HJ, Michielsen EC, Verstappen J, Fasse E, Joosten I. Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis. Transplantation 2003;75:1581-90.
    • (2003) Transplantation , vol.75 , pp. 1581-1590
    • Koenen, H.J.1    Michielsen, E.C.2    Verstappen, J.3    Fasse, E.4    Joosten, I.5
  • 15
    • 77958553914 scopus 로고    scopus 로고
    • Sirolimus immunosuppression for graft-versus-host disease prophylaxis and therapy: an update
    • Cutler C, Antin JH. Sirolimus immunosuppression for graft-versus-host disease prophylaxis and therapy: an update. Curr Opin Hematol 2010;17:500-4.
    • (2010) Curr Opin Hematol , vol.17 , pp. 500-504
    • Cutler, C.1    Antin, J.H.2
  • 16
    • 33947578933 scopus 로고    scopus 로고
    • Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation
    • Cutler C, Li S, Ho VT, Koreth J, Alyea E, Soiffer RJ, Antin JH. Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation. Blood 2007;109:3108-14.
    • (2007) Blood , vol.109 , pp. 3108-3114
    • Cutler, C.1    Li, S.2    Ho, V.T.3    Koreth, J.4    Alyea, E.5    Soiffer, R.J.6    Antin, J.H.7
  • 17
    • 20244362642 scopus 로고    scopus 로고
    • Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens
    • Cutler C, Li S, Kim HT, et al. Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens. Biol Blood Marrow Transplant 2005;11:383-8.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 383-388
    • Cutler, C.1    Li, S.2    Kim, H.T.3
  • 18
    • 0141724896 scopus 로고    scopus 로고
    • Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation
    • Schaffer M, Aldener-Cannava A, Remberger M, Ringden O, Olerup O. Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation. Tissue Antigens 2003;62:243-50.
    • (2003) Tissue Antigens , vol.62 , pp. 243-250
    • Schaffer, M.1    Aldener-Cannava, A.2    Remberger, M.3    Ringden, O.4    Olerup, O.5
  • 19
    • 57049148499 scopus 로고    scopus 로고
    • Unrelated cord blood and mismatched unrelated volunteer donor transplants, two alternatives in patients who lack an HLA-identical donor
    • Ringden O, Okas M, Uhlin M, Uzunel M, Remberger M, Mattsson J. Unrelated cord blood and mismatched unrelated volunteer donor transplants, two alternatives in patients who lack an HLA-identical donor. Bone Marrow Transplant 2008;42:643-8.
    • (2008) Bone Marrow Transplant , vol.42 , pp. 643-648
    • Ringden, O.1    Okas, M.2    Uhlin, M.3    Uzunel, M.4    Remberger, M.5    Mattsson, J.6
  • 20
    • 0033566347 scopus 로고    scopus 로고
    • Peripheral blood stem cell transplantation from unrelated donors: a comparison with marrow transplantation
    • Ringden O, Remberger M, Runde V, et al. Peripheral blood stem cell transplantation from unrelated donors: a comparison with marrow transplantation. Blood 1999;94:455-64.
    • (1999) Blood , vol.94 , pp. 455-464
    • Ringden, O.1    Remberger, M.2    Runde, V.3
  • 21
    • 0022952392 scopus 로고
    • Busulphan and cyclophosphamide cause little early toxicity during displacement bone marrow transplantation in fifty children
    • Shaw PJ, Hugh-Jones K, Hobbs JR, Downie CJ, Barnes R. Busulphan and cyclophosphamide cause little early toxicity during displacement bone marrow transplantation in fifty children. Bone Marrow Transplant 1986;1:193-200.
    • (1986) Bone Marrow Transplant , vol.1 , pp. 193-200
    • Shaw, P.J.1    Hugh-Jones, K.2    Hobbs, J.R.3    Downie, C.J.4    Barnes, R.5
  • 22
    • 0032758059 scopus 로고    scopus 로고
    • Effect on cytokine release and graft-versus-host disease of different anti-T cell antibodies during conditioning for unrelated haematopoietic stem cell transplantation
    • Remberger M, Svahn BM, Hentschke P, Lofgren C, Ringden O. Effect on cytokine release and graft-versus-host disease of different anti-T cell antibodies during conditioning for unrelated haematopoietic stem cell transplantation. Bone Marrow Transplant 1999;24:823-30.
    • (1999) Bone Marrow Transplant , vol.24 , pp. 823-830
    • Remberger, M.1    Svahn, B.M.2    Hentschke, P.3    Lofgren, C.4    Ringden, O.5
  • 23
    • 33645046392 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem cell transplantation for inherited disorders: experience in a single center
    • Ringden O, Remberger M, Svahn BM, et al. Allogeneic hematopoietic stem cell transplantation for inherited disorders: experience in a single center. Transplantation 2006;81:718-25.
    • (2006) Transplantation , vol.81 , pp. 718-725
    • Ringden, O.1    Remberger, M.2    Svahn, B.M.3
  • 24
    • 0023840014 scopus 로고
    • Cyclosporine v methotrexate for graft-v-host disease prevention in patients given marrow grafts for leukemia: long-term follow-up of three controlled trials
    • Storb R, Deeg HJ, Fisher L, et al. Cyclosporine v methotrexate for graft-v-host disease prevention in patients given marrow grafts for leukemia: long-term follow-up of three controlled trials. Blood 1988;71:293-8.
    • (1988) Blood , vol.71 , pp. 293-298
    • Storb, R.1    Deeg, H.J.2    Fisher, L.3
  • 25
    • 0029073339 scopus 로고
    • Similar incidence of graft-versus-host disease using HLA-A, -B and -DR identical unrelated bone marrow donors as with HLA-identical siblings
    • Ringden O, Remberger M, Persson U, et al. Similar incidence of graft-versus-host disease using HLA-A, -B and -DR identical unrelated bone marrow donors as with HLA-identical siblings. Bone Marrow Transplant 1995;15:619-25.
    • (1995) Bone Marrow Transplant , vol.15 , pp. 619-625
    • Ringden, O.1    Remberger, M.2    Persson, U.3
  • 26
    • 0037114629 scopus 로고    scopus 로고
    • Home care during the pancytopenic phase after allogeneic hematopoietic stem cell transplantation is advantageous compared with hospital care
    • Svahn BM, Remberger M, Myrback KE, Holmberg K, Eriksson B, Hentschke P, Aschan J, Barkholt L, Ringden O. Home care during the pancytopenic phase after allogeneic hematopoietic stem cell transplantation is advantageous compared with hospital care. Blood 2002;100:4317-24.
    • (2002) Blood , vol.100 , pp. 4317-4324
    • Svahn, B.M.1    Remberger, M.2    Myrback, K.E.3    Holmberg, K.4    Eriksson, B.5    Hentschke, P.6    Aschan, J.7    Barkholt, L.8    Ringden, O.9
  • 27
    • 0035195063 scopus 로고    scopus 로고
    • Leukemia lineage-specific chimerism analysis is a sensitive predictor of relapse in patients with acute myeloid leukemia and myelodysplastic syndrome after allogeneic stem cell transplantation
    • Mattsson J, Uzunel M, Tammik L, Aschan J, Ringden O. Leukemia lineage-specific chimerism analysis is a sensitive predictor of relapse in patients with acute myeloid leukemia and myelodysplastic syndrome after allogeneic stem cell transplantation. Leukemia 2001;15:1976-85.
    • (2001) Leukemia , vol.15 , pp. 1976-1985
    • Mattsson, J.1    Uzunel, M.2    Tammik, L.3    Aschan, J.4    Ringden, O.5
  • 28
    • 11144354152 scopus 로고    scopus 로고
    • Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation
    • Cutler C, Kim HT, Hochberg E, et al. Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation. Biol Blood Marrow Transplant 2004;10:328-36.
    • (2004) Biol Blood Marrow Transplant , vol.10 , pp. 328-336
    • Cutler, C.1    Kim, H.T.2    Hochberg, E.3
  • 29
    • 37348999625 scopus 로고    scopus 로고
    • Graft failure after allogeneic hematopoietic cell transplantation
    • Mattsson J, Ringden O, Storb R. Graft failure after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2008;14(Suppl 1):165-70.
    • (2008) Biol Blood Marrow Transplant , vol.14 , Issue.SUPPL. 1 , pp. 165-170
    • Mattsson, J.1    Ringden, O.2    Storb, R.3
  • 30
    • 0035865226 scopus 로고    scopus 로고
    • T cell mixed chimerism is significantly correlated to a decreased risk of acute graft-versus-host disease after allogeneic stem cell transplantation
    • Mattsson J, Uzunel M, Remberger M, Ringden O. T cell mixed chimerism is significantly correlated to a decreased risk of acute graft-versus-host disease after allogeneic stem cell transplantation. Transplantation 2001;71:433-9.
    • (2001) Transplantation , vol.71 , pp. 433-439
    • Mattsson, J.1    Uzunel, M.2    Remberger, M.3    Ringden, O.4
  • 31
    • 0042090489 scopus 로고    scopus 로고
    • Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas
    • Nepomuceno RR, Balatoni CE, Natkunam Y, Snow AL, Krams SM, Martinez OM. Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas. Cancer Res 2003;63:4472-80.
    • (2003) Cancer Res , vol.63 , pp. 4472-4480
    • Nepomuceno, R.R.1    Balatoni, C.E.2    Natkunam, Y.3    Snow, A.L.4    Krams, S.M.5    Martinez, O.M.6
  • 32
    • 34547123123 scopus 로고    scopus 로고
    • Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysis
    • Marty FM, Bryar J, Browne SK, et al. Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysis. Blood 2007;110:490-500.
    • (2007) Blood , vol.110 , pp. 490-500
    • Marty, F.M.1    Bryar, J.2    Browne, S.K.3
  • 34
    • 58149388343 scopus 로고    scopus 로고
    • Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation
    • Cutler C, Stevenson K, Kim HT, et al. Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation. Blood 2008;112:4425-31.
    • (2008) Blood , vol.112 , pp. 4425-4431
    • Cutler, C.1    Stevenson, K.2    Kim, H.T.3
  • 35
    • 0037623421 scopus 로고    scopus 로고
    • Ten years of sirolimus therapy in orthotopic liver transplant recipients
    • Neff GW, Montalbano M, Tzakis AG. Ten years of sirolimus therapy in orthotopic liver transplant recipients. Transplant Proc 2003;35(3 Suppl):209S-16S.
    • (2003) Transplant Proc , vol.35 , Issue.SUPPL. 3
    • Neff, G.W.1    Montalbano, M.2    Tzakis, A.G.3


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