Sputum inflammation predicts exacerbations after cessation of inhaled corticosteroids in COPD

Respiratory Medicine

Volumn 105, Issue 12, 2011, Pages 1853-1860

  Liesker, Jeroen J W ^a   Bathoorn, Erik ^a   Postma, Dirkje S ^a   Vonk, Judith M ^a   Timens, Wim ^a   Kerstjens, Huib A M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Airway inflammation; COPD exacerbation; Eosinophil; Inhaled corticosteroids; Sputum induction

Indexed keywords

C REACTIVE PROTEIN; CELL ADHESION MOLECULE; CORTICOSTEROID; DESMOSINE; EOSINOPHIL CATIONIC PROTEIN; GAMMA INTERFERON; HEMOXYGENASE 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 5; LEUKOTRIENE B4; MESSENGER RNA; MYELOPEROXIDASE; OXYGENASE; RANTES; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO ACID URINE LEVEL; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CORTICOSTEROID THERAPY; DISEASE EXACERBATION; DRUG WITHDRAWAL; EOSINOPHIL COUNT; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; GENE EXPRESSION PROFILING; HEALTH STATUS; HUMAN; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PLETHYSMOGRAPHY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEASONAL VARIATION; SPIROMETRY; SPUTUM ANALYSIS; VITAL CAPACITY;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ADULT; AGED; DRUG ADMINISTRATION SCHEDULE; EOSINOPHILS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEUTROPHILS; PLETHYSMOGRAPHY, WHOLE BODY; PRACTICE GUIDELINES AS TOPIC; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; QUESTIONNAIRES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SEVERITY OF ILLNESS INDEX; SPUTUM;

EID: 81155152484     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2011.07.002     Document Type: Article

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