Covalently immobilized gelatin gradients within three-dimensional porous scaffolds

Chinese Science Bulletin

Volumn 54, Issue 18, 2009, Pages 3174-3180

  Wu, JinDan ^a   Tan, HuaPing ^a   Li, LinHui ^a   Gao, ChangYou ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Aminolysis; Chondrocyte; Gelatin; Gradient; Poly(L lactic acid); Scaffold

Indexed keywords

EID: 81155146845     PISSN: 10016538     EISSN: 18619541     Source Type: Journal    
DOI: 10.1007/s11434-009-0215-2     Document Type: Article

References (28)

1. Grodzinski J.J. Polymers for tissue engineering, medical devices, and regerative medicine. Concise general review of recent studies. Polym Adv Technol, 2006, 17: 395-418
2. Yasuhiko T. Tissue regeneratioin based on tissue engineering technology. Congenit Anom, 2004, 44: 111-124
3. Wang S.J, Wajeeh Saadi, Lin Francis, et al. Differential effects of EGF gradient profiles on MDA-MB-231 breast cancer cell chemo-taxis. Exp Cell Res, 2004, 300: 180-189
4. Adams D.N, Kao E.Y.-C, Hypolite C.L, et al. Growth cones turn and migrate up an immobilized gradient of the laminin IKVAV Peptide. Inc J Neurobiol, 2005, 62: 134-137
5. Gunawan R.C, Silverstre J, Gaskins H.R, et al. Cell migration and polarity on microfabricated gradients of extracellular matrix proteins. Langmuir, 2006, 22: 4250-4258
6. Maheshwari G, Brown G, Lauffenburger D.A, et al. Cell adhesion and motility depend on nanoscale RGD clustering. J Cell Sci, 2000, 113: 1677-1686
7. Lo C.M, Wang H.B, Dembo M, et al. Cell movement is guided by the rigidity of the substrate. J Biophys, 2000, 79: 144-152
8. Wong J.C, Velasco A, Rajagopalan P, et al. Directed movement of vascular smooth muscle cells on gradient-compliant hydrogel. Langmuir, 2003, 19: 1908-1913
9. Kunzler T.P, Drobek T, Schuler M, et al. Systematic study of os-teoblast and fibroblast response to roughness by means of surface-morphology gradients. Biomaterials, 2007, 28: 2175-2182
10. Lee J.H, Lee H.B. Platelet adhesion onto wettability gradient surfaces in the absence and presence of plasma protrins. J Biomed Mater Res, 1998, 41: 304-311
11. Ridley A.J, Schwartz M.A, Burridge K, et al. Cell migration: Integrating signals from front to back. Science, 2003, 302: 1704-1709
12. Kumar G, Ho C.C, Co C.C, et al. Guiding cell migration using oneway micropattern arrays. Adv Mater, 2007, 19: 1084-1090
13. Tan H.P, Wan L, Wu J.D, et al. Microscale control over collagen gradient on poly(L-lactide) membrane surface for manipulating chondrocyte distribution. Colloids Surf B Biointerfaces, 2008, 67: 210-215
14. Ma Z.W, Gao C.Y, Gong Y.H, et al. Paraffin spheres as porogen to fabricate poly(L-lactic acid) scaffolds with improved cytocompati-bility for cartilage tissue engineering. J Biomed Mater Res Part B: Apple Biomater, 2003, 67B: 610-617
15. Beningo K.A, Dembo M, Wang Y.L. Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors. Proc Natl Acad Sci USA, 2004, 101: 10824-10829
16. Vepari C.P, Kaplan D.L. Covalently immobilized enzyme gradients within three-dimensional porous scaffolds. Biotechnol Bioeng, 2006, 93: 1130-1137
17. Nam Y.S, Park T.G. Biodegradable polymeric microcellular foams by modified thermally induced phase separation method. Biomaterials, 1999, 20: 1783-1790
18. Gao C.Y, Li A, Feng L.X, et al. Factors controlling surface morphology of porous polystyrene membranes prepared by thermally induced phased separation. Polym Int, 2000, 49: 323-328
19. Ma P.X, Choi J.W. Biodegradable polymer scaffolds with well-defined interconnected spherical pore network. Tissue Eng, 2001, 7: 2333
20. Nazarov R, Jin H.J, Kaplan D.L. Porous 3-D scaffolds from regenerated silk fibroin. Biomacromolecules, 2004, 5: 718-726
21. Hideto T, Michihiko N, Makoto H et al. Electrospinning of poly (lactic acid) stereocomplex nanofibers. Biomacromolecules, 2006, 7: 3316-3320
22. Tan H.P, Wu J.D, Lao L.H, et al. Gelatin/chitosan/hyaluronan scaffold integrated with PLGA microspheres for cartilage tissue engineering. Acta Biomater, 2009, 5: 328-337
23. Gong Y.H, Zhou Q.L, Gao C.Y, et al. In vitro and in vivo degradabil-ity and cytocompatibility of poly(L-lactic acid) scaffold fabricated by a gelatin particle leaching method. Acta Biomater, 2007, 3: 531-540
24. Zhou Q.L, Gong Y.H, Gao C.Y. Microstructure and mechanical properties of poly(L-lactide) scaffolds fabricated by gelatin particle leaching method. J Appl Polym Sci, 2005, 98: 1373-1379
25. Zhu Y.B, Gao C.Y, He T, et al. Endothelium regeneration on luminal surface of polyurethane vascular scaffold modified with diamine and covalently grafted with gelatin. Biomaterials, 2004, 25: 423-430
26. Zhu Y.B, Gao C.Y, Liu Y.X, et al. Immobilization of biomacro-molecules onto aminolyzed poly(L-lactic acid) toward acceleration of endothelium regeneration. Tissue Eng, 2004, 10: 53-60
27. Zhu Y.B, Gao C.Y, Liu Y.X, et al. Endothelial cell functions in vitro cultured on poly(L-lactic acid) membranes modified with different methods. J Biomed Mater Res, 2004, 69A: 436-443
28. Yu X, Wang Z.Q, Jiang Y.G, et al. Surface gradient material: from super-hydrophobicity to superhydrophilicity. Langmuir, 2006, 22: 4483-4486