Long-term reactions to genetic testing for BRCA1 and BRCA2 mutations: Does time heal women's concerns?

Journal of Clinical Oncology

Volumn 29, Issue 32, 2011, Pages 4302-4306

  Halbert, Chanita Hughes ^a   Stopfer, Jill E ^a   McDonald, Jasmine ^a   Weathers, Benita ^a   Collier, Aliya ^a   Troxel, Andrea B ^a   Domchek, Susan ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CA 125 ANTIGEN;

ADULT; ARTICLE; BEHAVIOR; BREAST CANCER; CANCER PATIENT; CANCER SCREENING; CLINICAL EVALUATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DISTRESS SYNDROME; FAMILY; FEMALE; GENE MUTATION; GENETIC SCREENING; HETEROZYGOTE; HISTOPATHOLOGY; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MAMMOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; OBSERVATIONAL STUDY; OVARY CANCER; PATIENT COUNSELING; PRIORITY JOURNAL; SCORING SYSTEM; TRANSVAGINAL ECHOGRAPHY; UNCERTAINTY;

ADULT; AGED; BREAST NEOPLASMS; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC TESTING; HUMANS; MIDDLE AGED; MUTATION; OVARIAN NEOPLASMS; REGRESSION ANALYSIS;

EID: 81155133279     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2010.33.1561     Document Type: Article

References (18)

1. Croyle RT, Smith KR, Botkin JR, et al.: Psychological responses to BRCA1 mutation testing: Preliminary findings. Health Psychol 16:63-72, 1997 (Pubitemid 127465954)
2. Schwartz MD, Peshkin BN, Hughes C, et al.: Impact of BRCA1/BRCA2 mutation testing on psychological distress in a clinic-based sample. J Clin Oncol 20:514-520, 2002 (Pubitemid 34072536)
3. Cella D, Hughes C, Peterman A, et al.: A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire. Health Psychol 21:564-572, 2002 (Pubitemid 35244769)
4. Botkin JR, Smith KR, Croyle RT, et al.: Genetic testing for a BRCA1 mutation: Prophylactic surgery and screening behavior in women 2 years post testing. Am J Med Genet A 118A:201-209, 2003 (Pubitemid 37063927)
5. Bradbury AR, Ibe CN, Dignam JJ, et al.: Uptake and timing of bilateral prophylactic salpingooophorectomy among BRCA1 and BRCA2 mutation carriers. Genet Med 10:161-166, 2008 (Pubitemid 351416811)
6. Beran TM, Stanton AL, Kwan L, et al.: The trajectory of psychological impact in BRCA1/2 genetic testing: Does time heal? Ann Behav Med 36:107-116, 2008
7. van Oostrom I, Meijers-Heijboer H, Lodder LN, et al.: Long-term psychological impact of carrying a BRCA1/2 mutation and prophylactic surgery: A 5-year follow-up study. J Clin Oncol 21:3867-3874, 2003 (Pubitemid 46606243)
8. Charles S, Kessler L, Stopfer JE, et al.: Satisfaction with genetic counseling for BRCA1 and BRCA2 mutations among African American women. Patient Educ Couns 63:196-204, 2006 (Pubitemid 44331550)
9. Halbert CH, Kessler L, Stopfer JE, et al.: Low rates of acceptance of BRCA1 and BRCA2 test results among African American women at increased risk for hereditary breast-ovarian cancer. Genet Med 8:576-582, 2006 (Pubitemid 44402035)
10. Armstrong K, Weber B, Ubel PA, et al.: Individualized survival curves improve satisfaction with cancer risk management decisions in women with BRCA1/2 mutations. J Clin Oncol 23:9319-9328, 2005
11. Lerman C, Hughes C, Croyle RT, et al.: Prophylactic surgery decisions among BRCA1/2 families. Prev Med 31:75-80, 2000
12. Schwartz MD, Kaufman E, Peshkin BN, et al.: Bilateral prophylactic oophorectomy and ovarian cancer screening following BRCA1/BRCA2 mutation testing. J Clin Oncol 21:4034-4041, 2003 (Pubitemid 46606219)
13. Graves KD, Wenzel L, Schwartz MD, et al.: Randomized controlled trial of a psychosocial telephone counseling intervention in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev 19:648-654, 2010
14. Schwartz MD, Valdimarsdottir HB, DeMarco TA, et al.: Randomized trial of a decision aid for BRCA1/BRCA2 mutation carriers: Impact on measures of decision making and satisfaction. Health Psychol 28:11-19, 2009
15. Hamilton JG, Lobel M, Moyer A: Emotional distress following genetic testing for hereditary breast and ovarian cancer: A meta-analytic review. Health Psychol 28:510-518, 2009
16. Coyne JC, Benazon NR, Gaba CG, et al.: Distress and psychiatric morbidity among women from high-risk breast and ovarian cancer families. J Consult Clin Psychol 68:864-874, 2000
17. Halbert CH, Wenzel L, Lerman C, et al.: Predictors of participation in psychosocial telephone counseling following genetic testing for BRCA1 and BRCA2 mutations. Cancer Epidemiol Biomarkers Prev 13:875-881, 2004 (Pubitemid 38737879)
18. Lerman C, Narod S, Schulman K, et al.: BRCA1 testing in families with hereditary breast-ovarian cancer: A prospective study of patient decision making and outcomes. JAMA 275:1885-1892, 1996 (Pubitemid 26196448)