Analysis of the glycoproteome of Toxoplasma gondii using lectin affinity chromatography and tandem mass spectrometry

Microbes and Infection

Volumn 13, Issue 14-15, 2011, Pages 1199-1210

  Luo, Qilie ^a   Upadhya, Rajendra ^a   Zhang, Hong ^a   Madrid Aliste, Carlos ^a   Nieves, Edward ^a   Kim, Kami ^a   Angeletti, Ruth Hogue ^a   Weiss, Louis M ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Glycoproteome; Glycosylation; Lectin chromatography; Membrane proteins; Toxoplasma

Indexed keywords

ABC TRANSPORTER; ACTIN; APICAL MEMBRANE ANTIGEN 1; CARBAMOYL PHOSPHATE SYNTHASE; CARBOHYDRATE; CYSTEINE REPEAT MODULAR PROTEIN; DNA DIRECTED DNA POLYMERASE BETA; ELONGATION FACTOR 1; GLUCOSE 6 PHOSPHATE 1 DEHYDROGENASE; GLUTATHIONE REDUCTASE; GLYCINE RICH PROTEIN 2; GLYCOPEPTIDE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HYPOTHETICAL PROTEIN; KELCH MOTIF DOMAIN CONTAINING PROTEIN; KINESIN; MEMBRANE PROTEIN; MYOSIN ADENOSINE TRIPHOSPHATASE; OXIDOREDUCTASE; PROTEIN DISULFIDE ISOMERASE; PROTEIN SERINE THREONINE KINASE VPS15; PROTOZOAL PROTEIN; RIBOSOME RNA; RNA BINDING PROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN; THIOREDOXIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; UROPORPHYRINOGEN DECARBOXYLASE;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING AFFINITY; CYTOPLASM; HYDROPHOBICITY; MOLECULAR RECOGNITION; NONHUMAN; PEPTIDE MAPPING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN ISOLATION; SERIAL LECTIN AFFINITY CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, PROTOZOAN; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATOGRAPHY, AFFINITY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBROBLASTS; GLYCOMICS; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; LECTINS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; TANDEM MASS SPECTROMETRY; TOXOPLASMA; TOXOPLASMOSIS; TRYPSIN;

TOXOPLASMA; TOXOPLASMA GONDII;

EID: 81155132158     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2011.08.013     Document Type: Article

References (30)

1. Toxoplasma gondi: The Model Apicomplexan: Perspectives and Methods 2007, Elsevier (Academic Press), Amsterdam, Boston. L.M. Weiss, K. Kim (Eds.).
2. Tenter A.M., Heckeroth A.R., Weiss L.M. Toxoplasma gondii: from animals to humans. Int. J. Parasitol. 2000, 30:1217-1258.
3. Dubey J.P. Advances in the life cycle of Toxoplasma gondii. Int. J. Parasitol. 1998, 28:1019-1024.
4. Wong S.Y., Remington J.S. Biology of Toxoplasma gondii. AIDS 1993, 7:299-316.
5. Marino K., Bones J., Kattla J.J., Rudd P.M. A systematic approach to protein glycosylation analysis: a path through the maze. Nat. Chem. Biol. 2010, 6:713-723.
6. Vagin O., Kraut J.A., Sachs G. Role of N-glycosylation in trafficking of apical membrane proteins in epithelia. Am. J. Physiol. Ren. Physiol. 2009, 296:F459-F469.
7. Tian E., Ten Hagen K.G. Recent insights into the biological roles of mucin-type O-glycosylation. Glycoconj. J. 2009, 26:325-334.
8. Protein Glycosylation 1998, Kluwer Academic Publishers, Boston. R.M. Bill, L. Revers, I.B.H. Wilson (Eds.).
9. Introduction to Glycobiology 2006, Oxford University Press, Oxford, New York. M.E. Taylor, K. Drickamer (Eds.).
10. Luk F.C., Johnson T.M., Beckers C.J. N-linked glycosylation of proteins in the protozoan parasite Toxoplasma gondii. Mol. Biochem. Parasitol. 2008, 157:169-178.
11. Garenaux E., Shams-Eldin H., Chirat F., Bieker U., Schmidt J., Michalski J.C., Cacan R., Guerardel Y., Schwarz R.T. The dual origin of Toxoplasma gondii N-glycans. Biochemistry 2008, 47:12270-12276.
12. Fauquenoy S., Morelle W., Hovasse A., Bednarczyk A., Slomianny C., Schaeffer C., Van Dorsselaer A., Tomavo S. Proteomics and glycomics analyses of N-glycosylated structures involved in Toxoplasma gondii--host cell interactions. Mol. Cell Proteomics 2008, 7:891-910.
13. Zhang Y.W., Halonen S.K., Ma Y.F., Wittner M., Weiss L.M. Initial characterization of CST1, a Toxoplasma gondii cyst wall glycoprotein. Infect. Immun. 2001, 69:501-507.
14. Samuelson J., Banerjee S., Magnelli P., Cui J., Kelleher D.J., Gilmore R., Robbins P.W. The diversity of dolichol-linked precursors to Asn-linked glycans likely results from secondary loss of sets of glycosyltransferases. Proc. Natl. Acad. Sci. U S A 2005, 102:1548-1553.
15. Stwora-Wojczyk M.M., Kissinger J.C., Spitalnik S.L., Wojczyk B.S. O-glycosylation in Toxoplasma gondii: identification and analysis of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases. Int. J. Parasitol. 2004, 34:309-322.
16. Dieckmann-Schuppert A., Bause E., Schwarz R.T. Glycosylation reactions in Plasmodium falciparum, Toxoplasma gondii, and Trypanosoma brucei brucei probed by the use of synthetic peptides. Biochim. Biophys. Acta 1994, 1199:37-44.
17. Stwora-Wojczyk M.M., Dzierszinski F., Roos D.S., Spitalnik S.L., Wojczyk B.S. Functional characterization of a novel Toxoplasma gondii glycosyltransferase: UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T3. Arch. Biochem. Biophys. 2004, 426:231-240.
18. Nakai K., Horton P. PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem. Sci. 1999, 24:34-36.
19. Che F.Y., Madrid-Aliste C., Burd B., Zhang H., Nieves E., Kim K., Fiser A., Angeletti R.H., Weiss L.M. Comprehensive proteomic analysis of membrane proteins in Toxoplasma gondii. Mol. Cell. Proteomics 2011, 10:M110.00745.
20. Madrid-Aliste C.J., Dybas J.M., Angeletti R.H., Weiss L.M., Kim K., Simon I., Fiser A. EPIC-DB: a proteomics database for studying Apicomplexan organisms. B.M.C. Genomics 2009, 10:38.
21. Dybas J.M., Madrid-Aliste C.J., Che F.Y., Nieves E., Rykunov D., Angeletti R.H., Weiss L.M., Kim K., Fiser A. Computational analysis and experimental validation of gene predictions in Toxoplasma gondii. PLoS One 2008, 3:e3899.
22. Chen Y., Yu P., Luo J., Jiang Y. Secreted protein prediction system combining CJ-SPHMM, TMHMM, and PSORT. Mamm. Genome 2003, 14:859-865.
23. Odenthal-Schnittler M., Tomavo S., Becker D., Dubremetz J.F., Schwarz R.T. Evidence for N-linked glycosylation in Toxoplasma gondii. Biochem. J. 1993, 291:713-721.
24. Dubey J.P., Lindsay D.S., Speer C.A. Structures of Toxoplasma gondii tachyzoites, bradyzoites, and sporozoites and biology and development of tissue cysts. Clin. Microbiol. Rev. 1998, 11:267-299.
25. Mercier C., Lecordier L., Darcy F., Deslee D., Murray A., Tourvieille B., Maes P., Capron A., Cesbron-Delauw M.F. Molecular characterization of a dense granule antigen (Gra 2) associated with the network of the parasitophorous vacuole in Toxoplasma gondii. Mol. Biochem. Parasitol. 1993, 58:71-82.
26. Blachly-Dyson E., Stevens T.H. Yeast carboxypeptidase Y can be translocated and glycosylated without its amino-terminal signal sequence. J. Cell Biol. 1987, 104:1183-1191.
27. Silve S., Monod M., Hinnen A., Haguenauer-Tsapis R. The yeast acid phosphatase can enter the secretory pathway without its N-terminal signal sequence. Mol. Cell Biol. 1987, 7:3306-3314.
28. Tutar L., Tutar Y. Heat shock proteins; an overview. Curr. Pharm. Biotechnol. 2010, 11:216-222.
29. Shonhai A. Plasmodial heat shock proteins: targets for chemotherapy. FEMS Immunol. Med. Microbiol. 2010, 58:61-74.
30. Stress Responses in Biology and Medicine: Stress of Life in Molecules, Cells, Organisms, and Psychosocial Communities 2007, Blackwell Pub. (New York Academy of Sciences), Boston, Mass. P. Csermely, T. Korcsmáros, K. Sulyok (Eds.).