Comparison of Symbicort® versus Pulmicort® on steroid pharmacodynamic markers in asthma patients

Respiratory Medicine

Volumn 105, Issue 12, 2011, Pages 1784-1789

  Essilfie Quaye, Sarah ^a   Ito, Kazuhiro ^a   Ito, Misako ^a   Kharitonov, Sergei A ^a   Barnes, Peter J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Asthma; Combination therapy; Cortosteroid; GR GRE; Phramacodynamic marker; Sputum macrophage

Indexed keywords

BUDESONIDE; BUDESONIDE PLUS FORMOTEROL; FORMOTEROL; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; OLIGONUCLEOTIDE; PLACEBO;

ADULT; ARTICLE; ASTHMA; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG MEGADOSE; DRUG RECEPTOR BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HORMONE RECEPTOR INTERACTION; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; LOW DRUG DOSE; LUNG ALVEOLUS MACROPHAGE; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPUTUM;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ADULT; ANTI-ASTHMATIC AGENTS; ASTHMA; BIOLOGICAL MARKERS; BRONCHODILATOR AGENTS; BUDESONIDE; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; DRUG THERAPY, COMBINATION; DUAL SPECIFICITY PHOSPHATASE 1; ENZYME-LINKED IMMUNOSORBENT ASSAY; ETHANOLAMINES; FEMALE; GLUCOCORTICOIDS; HUMANS; INTERLEUKIN-8; MALE; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPUTUM;

EID: 81155130861     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2011.08.020     Document Type: Article

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