Quantitative shot-gun proteomics and MS-based activity assay for revealing gender differences in enzyme contents for rat liver microsome

Journal of Proteomics

Volumn 74, Issue 12, 2011, Pages 2734-2744

  Huang, Hung Jen ^a   Tsai, Mei Ling ^b   Chen, Yen Wen ^c   Chen, Shu Hui ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL CENTRAL UNIVERSITY   (Taiwan)

Author keywords

Enzyme activity assay; MRM; Rat liver microsome; Sex dependent enzyme expression; Stable isotope dimethyl labelling

Indexed keywords

ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE 1; CARBOXYLESTERASE; CARBOXYLESTERASE 3; CYTOCHROME P450; CYTOCHROME P450 2A1; CYTOCHROME P450 2B; CYTOCHROME P450 2B3; CYTOCHROME P450 2C; CYTOCHROME P450 2C11; CYTOCHROME P450 2C12; CYTOCHROME P450 2C13; CYTOCHROME P450 2C7; CYTOCHROME P450 2C70; CYTOCHROME P450 2D; CYTOCHROME P450 2D26; CYTOCHROME P450 3A2; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LIVER CARBOXYLESTERASE; UDP GLUCURONOSYLTRANSFERASE 2B1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ISOLATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; FEMALE; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEX DIFFERENCE; SEX RATIO; SHOT GUN PROTEMICS; STRUCTURAL PROTEOMICS; TANDEM MASS SPECTROMETRY;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; ISOENZYMES; MALE; MASS SPECTROMETRY; MICROSOMES, LIVER; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS;

RATTUS;

EID: 81055140642     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2011.01.015     Document Type: Article

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