The importance of HT-ADME in drug discovery

Bioanalysis

Volumn 3, Issue 21, 2011, Pages 2385-2387

  Morgan, Daniel ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMBINATORIAL CHEMISTRY; COMPUTER PROGRAM; CONFERENCE PAPER; DATA MINING; DRUG ABSORPTION; DRUG DESIGN; DRUG DEVELOPMENT; DRUG EXCRETION; DRUG METABOLISM; HIGH THROUGHPUT SCREENING;

CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; SOFTWARE; TISSUE DISTRIBUTION;

EID: 81055125444     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.253     Document Type: Conference Paper

References (1)

1. Lipinski CA, Lombardo F, Dominy BW et al.Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings.Adv.Drug Del.Rev.46, 3-26 (2001). (Pubitemid 33653411)