메뉴 건너뛰기




Volumn 24, Issue 7, 2011, Pages 722-732

The BH3-mimetic ABT-737 inhibits allogeneic immune responses

Author keywords

ABT 737; Allograft; Apoptosis; Bcl 2; Immunosuppression; Transplantation

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; CYCLOSPORIN A; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN BCL 2;

EID: 80955180005     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2011.01272.x     Document Type: Article
Times cited : (13)

References (20)
  • 1
    • 10844292763 scopus 로고    scopus 로고
    • Immunosuppressive drugs for kidney transplantation
    • Halloran PF. Immunosuppressive drugs for kidney transplantation. N Engl J Med 2004; 351: 2715.
    • (2004) N Engl J Med , vol.351 , pp. 2715
    • Halloran, P.F.1
  • 2
    • 0037148840 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
    • Bouillet P, Purton JF, Godfrey DI, et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 2002; 415: 922.
    • (2002) Nature , vol.415 , pp. 922
    • Bouillet, P.1    Purton, J.F.2    Godfrey, D.I.3
  • 3
    • 0036234468 scopus 로고    scopus 로고
    • Pathways of apoptosis in lymphocyte development, homeostasis, and disease
    • Rathmell JC, Thompson CB. Pathways of apoptosis in lymphocyte development, homeostasis, and disease. Cell 2002; 109(Suppl.): S97.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Rathmell, J.C.1    Thompson, C.B.2
  • 4
    • 0345476290 scopus 로고    scopus 로고
    • Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
    • Wells AD, Li XC, Li Y, et al. Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nat Med 1999; 5: 1303.
    • (1999) Nat Med , vol.5 , pp. 1303
    • Wells, A.D.1    Li, X.C.2    Li, Y.3
  • 6
    • 20444486559 scopus 로고    scopus 로고
    • An inhibitor of Bcl-2 family proteins induces regression of solid tumours
    • Oltersdorf T, Elmore SW, Shoemaker AR, et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 2005; 435: 677.
    • (2005) Nature , vol.435 , pp. 677
    • Oltersdorf, T.1    Elmore, S.W.2    Shoemaker, A.R.3
  • 7
    • 42049104916 scopus 로고    scopus 로고
    • Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer
    • Hann CL, Daniel VC, Sugar EA, et al. Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer. Cancer Res 2008; 68: 2321.
    • (2008) Cancer Res , vol.68 , pp. 2321
    • Hann, C.L.1    Daniel, V.C.2    Sugar, E.A.3
  • 8
    • 77954649027 scopus 로고    scopus 로고
    • BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs
    • Carrington EM, Vikstrom IB, Light A, et al. BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs. Proc Natl Acad Sci USA 2010; 107: 10967.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10967
    • Carrington, E.M.1    Vikstrom, I.B.2    Light, A.3
  • 9
    • 67649198526 scopus 로고    scopus 로고
    • The Bcl-2 family antagonist ABT-737 significantly inhibits multiple animal models of autoimmunity
    • Bardwell PD, Gu J, McCarthy D, et al. The Bcl-2 family antagonist ABT-737 significantly inhibits multiple animal models of autoimmunity. J Immunol 2009; 182: 7482.
    • (2009) J Immunol , vol.182 , pp. 7482
    • Bardwell, P.D.1    Gu, J.2    McCarthy, D.3
  • 10
    • 0020566221 scopus 로고
    • Comparison of the cloned H-2Kbm1 variant gene with the H-2Kb gene shows a cluster of seven nucleotide differences
    • Schulze DH, Pease LR, Geier SS, et al. Comparison of the cloned H-2Kbm1 variant gene with the H-2Kb gene shows a cluster of seven nucleotide differences. Proc Natl Acad Sci USA 1983; 80: 2007.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 2007
    • Schulze, D.H.1    Pease, L.R.2    Geier, S.S.3
  • 11
    • 0028298811 scopus 로고
    • The degree of CD8 dependence of cytolytic T cell precursors is determined by the nature of the T cell receptor (TCR) and influences negative selection in TCR-transgenic mice
    • Auphan N, Curnow J, Guimezanes A, et al. The degree of CD8 dependence of cytolytic T cell precursors is determined by the nature of the T cell receptor (TCR) and influences negative selection in TCR-transgenic mice. Eur J Immunol 1994; 24: 1572.
    • (1994) Eur J Immunol , vol.24 , pp. 1572
    • Auphan, N.1    Curnow, J.2    Guimezanes, A.3
  • 12
    • 0035101372 scopus 로고    scopus 로고
    • Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: Distinct characteristics correlated with CD8 dependence
    • Guimezanes A, Barrett-Wilt GA, Gulden-Thompson P, et al. Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: distinct characteristics correlated with CD8 dependence. Eur J Immunol 2001; 31: 421.
    • (2001) Eur J Immunol , vol.31 , pp. 421
    • Guimezanes, A.1    Barrett-Wilt, G.A.2    Gulden-Thompson, P.3
  • 13
    • 0036200175 scopus 로고    scopus 로고
    • Oral interferon-alpha treatment of mice with cryoglobulinemic glomerulo-nephritis
    • Segerer S, Hudkins KL, Taneda S, et al. Oral interferon-alpha treatment of mice with cryoglobulinemic glomerulo-nephritis. Am J Kidney Dis 2002; 39: 876.
    • (2002) Am J Kidney Dis , vol.39 , pp. 876
    • Segerer, S.1    Hudkins, K.L.2    Taneda, S.3
  • 14
    • 0036151680 scopus 로고    scopus 로고
    • Cellular injury associated with renal thrombotic microangiopathy in human immunodeficiency virus-infected macaques
    • Segerer S, Eitner F, Cui Y, Hudkins KL, Alpers CE. Cellular injury associated with renal thrombotic microangiopathy in human immunodeficiency virus-infected macaques. J Am Soc Nephrol 2002; 13: 370.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 370
    • Segerer, S.1    Eitner, F.2    Cui, Y.3    Hudkins, K.L.4    Alpers, C.E.5
  • 15
    • 0037809473 scopus 로고    scopus 로고
    • Progress on isolation and short-term ex-vivo culture of highly purified non-apoptotic human intestinal epithelial cells (IEC)
    • Grossmann J, Walther K, Artinger M, et al. Progress on isolation and short-term ex-vivo culture of highly purified non-apoptotic human intestinal epithelial cells (IEC). Eur J Cell Biol 2003; 82: 262.
    • (2003) Eur J Cell Biol , vol.82 , pp. 262
    • Grossmann, J.1    Walther, K.2    Artinger, M.3
  • 16
    • 67650999861 scopus 로고    scopus 로고
    • Critical roles of Bim in T cell activation and T cell-mediated autoimmune inflammation in mice
    • Ludwinski MW, Sun J, Hilliard B, et al. Critical roles of Bim in T cell activation and T cell-mediated autoimmune inflammation in mice. J Clin Invest 2009; 119: 1706.
    • (2009) J Clin Invest , vol.119 , pp. 1706
    • Ludwinski, M.W.1    Sun, J.2    Hilliard, B.3
  • 17
    • 0030901628 scopus 로고    scopus 로고
    • Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2
    • Shibasaki F, Kondo E, Akagi T, McKeon F. Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2. Nature 1997; 386: 728.
    • (1997) Nature , vol.386 , pp. 728
    • Shibasaki, F.1    Kondo, E.2    Akagi, T.3    McKeon, F.4
  • 18
    • 60849086456 scopus 로고    scopus 로고
    • Bcl-2 inhibitors: Small molecules with a big impact on cancer therapy
    • Vogler M, Dinsdale D, Dyer MJ, Cohen GM. Bcl-2 inhibitors: small molecules with a big impact on cancer therapy. Cell Death Differ 2009; 16: 360.
    • (2009) Cell Death Differ , vol.16 , pp. 360
    • Vogler, M.1    Dinsdale, D.2    Dyer, M.J.3    Cohen, G.M.4
  • 19
    • 77956914323 scopus 로고    scopus 로고
    • The BH3-mimetic ABT-737 induces mast cell apoptosis in vitro and in vivo: Potential for therapeutics
    • Karlberg M, Ekoff M, Huang DC, Mustonen P, Harvima IT, Nilsson G. The BH3-mimetic ABT-737 induces mast cell apoptosis in vitro and in vivo: potential for therapeutics. J Immunol 2010; 185: 2555.
    • (2010) J Immunol , vol.185 , pp. 2555
    • Karlberg, M.1    Ekoff, M.2    Huang, D.C.3    Mustonen, P.4    Harvima, I.T.5    Nilsson, G.6
  • 20
    • 40849129529 scopus 로고    scopus 로고
    • A phase 1/2a study evaluating the safety, pharmacokinetics, and efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies
    • Abstract 1371
    • Wilson WH, Tulpule A, Levine AM, et al. A phase 1/2a study evaluating the safety, pharmacokinetics, and efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies. Blood 2007; 110: Abstract 1371.
    • (2007) Blood , vol.110
    • Wilson, W.H.1    Tulpule, A.2    Levine, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.