An association between Helicobacter pylori infection and cognitive function in children at early school age: A community-based study

BMC Pediatrics

Volumn 11, Issue , 2011, Pages

  Muhsen, Khitam ^a   Ornoy, Asher ^b   Akawi, Ashraf ^a   Alpert, Gershon ^c   Cohen, Dani ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b HEBREW UNIVERSITY   (Israel)

^c CLALIT HEALTH SERVICES   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHILD; COGNITION; COMMUNITY CARE; FEMALE; HELICOBACTER INFECTION; HUMAN; INTELLIGENCE QUOTIENT; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; NUTRITIONAL ASSESSMENT; PRESCHOOL CHILD; SCHOOL CHILD; SOCIAL STATUS; SOCIOECONOMICS; AGE; DEMOGRAPHY; HELICOBACTER PYLORI; IMMUNOLOGY; INTELLIGENCE; INTELLIGENCE TEST; PSYCHOLOGICAL ASPECT; RETROSPECTIVE STUDY; RISK FACTOR;

AGE FACTORS; CHILD; COGNITION; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTELLIGENCE; INTELLIGENCE TESTS; MALE; RESIDENCE CHARACTERISTICS; RETROSPECTIVE STUDIES; RISK FACTORS; SOCIOECONOMIC FACTORS;

EID: 80955173598     PISSN: None     EISSN: 14712431     Source Type: Journal    
DOI: 10.1186/1471-2431-11-43     Document Type: Article

References (33)

1. Berkman DS, Lescano AG, Gilman RH, Lopez SL, Black MM. Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study. Lancet 2002, 359:564-571. 10.1016/S0140-6736(02)07744-9, 11867110.
2. Niehaus MD, Moore SR, Patrick PD, Derr LL, Lorntz B, Lima AA, Guerrant RL. Early childhood diarrhea is associated with diminished cognitive function 4 to 7 years later in children in a northeast Brazilian shantytown. Am J Trop Med Hyg 2002, 66:590-593.
3. Simsek Z, Zeyrek FY, Kurcer MA. Effect of Giardia infection on growth and psychomotor development of children aged 0-5 years. J Trop Pediatr 2004, 50:90-93. 10.1093/tropej/50.2.90, 15088797.
4. Lorntz B, Soares AM, Moore SR, Pinkerton R, Gansneder B, Bovbjerg VE, Guyatt H, Lima AM, Guerrant RL. Early childhood diarrhea predicts impaired school performance. Pediatr Infect Dis J 2006, 25:513-520. 10.1097/01.inf.0000219524.64448.90, 16732149.
5. Rothenbacher D, Inceoglu J, Bode G, Brenner H. Acquisition of Helicobacter pylori infection in a high-risk population occurs within the first 2 years of life. J Pediatr 2000, 136:744-748.
6. Torres J, Perez-Perez G, Goodman KJ, Atherton JC, Gold BD, Harris PR, la Garza AM, Guarner J, Munoz O. A comprehensive review of the natural history of Helicobacter pylori infection in children. Arch Med Res 2000, 31:431-469. 10.1016/S0188-4409(00)00099-0, 11179581.
7. Malaty HM, El-Kasabany A, Graham DY, Miller CC, Reddy SG, Srinivasan SR, Yamaoka Y, Berenson GS. Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood. Lancet 2002, 359:931-935. 10.1016/S0140-6736(02)08025-X, 11918912.
8. Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med 2002, 347:1175-1186. 10.1056/NEJMra020542, 12374879.
9. The International Agency for Research on Cancer: World Health Organization Infection with Helicobacter pylori. 2009, The International Agency for Research on Cancer: World Health Organization., http://monographs.iarc.fr/ENG/Monographs/vol61/mono61-8.pdf
10. Cardenas VM, Mulla ZD, Ortiz M, Graham DY. Iron deficiency and Helicobacter pylori infection in the United States. Am J Epidemiol 2006, 163:127-134.
11. Choe YH, Kwon YS, Jung MK, Kang SK, Hwang TS, Hong YC. Helicobacter pylori-associated iron-deficiency anemia in adolescent female athletes. J Pediatr 2001, 139:100-104. 10.1067/mpd.2001.114700, 11445801.
12. Muhsen K, Barak M, Shifnaidel L, Nir A, Bassal R, Cohen D. Helicobacter pylori infection is associated with low serum ferritin levels in Israeli Arab children: a seroepidemiologic study. J Pediatr Gastroenterol Nutr 2009, 49:262-264. 10.1097/MPG.0b013e31818f0a0d, 19525869.
13. Muhsen K, Cohen D. Helicobacter pylori infection and iron stores: a systematic review and meta-analysis. Helicobacter 2008, 13:323-340. 10.1111/j.1523-5378.2008.00617.x, 19250507.
14. Baggett HC, Parkinson AJ, Muth PT, Gold BD, Gessner BD. Endemic iron deficiency associated with Helicobacter pylori infection among school-aged children in Alaska. Pediatrics 2006, 117:e396-e404. 10.1542/peds.2005-1129, 16452320.
15. Choi JW. Association between Helicobacter pylori infection and iron deficiency varies according to age in healthy adolescents. Acta Haematol 2007, 117:197-199. 10.1159/000098272, 17199079.
16. Lozoff B, Jimenez E, Wolf AW. Long-term developmental outcome of infants with iron deficiency. N Engl J Med 1991, 325:687-694. 10.1056/NEJM199109053251004, 1870641.
17. Lozoff B, Jimenez E, Smith JB. Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years. Arch Pediatr Adolesc Med 2006, 160:1108-1113. 10.1001/archpedi.160.11.1108, 1866361, 17088512.
18. Palti H, Pevsner B, Adler B. Does anemia in infancy affect achievement on developmental and intelligence tests?. Hum Biol 1983, 55:183-194.
19. Soemantri AG, Pollitt E, Kim I. Iron deficiency anemia and educational achievement. Am J Clin Nutr 1985, 42:1221-1228.
20. Lee A. Early influences and childhood development. Does helicobacter play a role?. Helicobacter 2007, 12(Suppl 2):69-74.
21. Windle HJ, Kelleher D, Crabtree JE. Childhood Helicobacter pylori infection and growth impairment in developing countries: a vicious cycle?. Pediatrics 2007, 119:e754-e759. 10.1542/peds.2006-2196, 17325213.
22. Israel Central Bureau of Statistics The Arab Population 2008. 2011, State of Israel, (Hebrew), Israel Central Bureau of Statistics., http://www.cbs.gov.il/www/statistical/arab_pop08.pdf
23. Muhsen K, Athamna A, Athamna M, Spungin-Bialik A, Cohen D. Prevalence and risk factors of Helicobacter pylori infection among healthy 3- to 5-year-old Israeli Arab children. Epidemiol Infect 2006, 134:990-996. 10.1017/S0950268806006030, 2870488, 16512967.
24. Israel Central Bureau of Statistics Statistical Abstract of Israel 2008. 2008, Jerusalem. State of Israel, Publication number 59. Israel. (Hebrew) (Accessed 20, February 2009), Israel Central Bureau of Statistics., http://www.cbs.gov.il/reader/
25. Israel Central Bureau of Statistics Characterization and Classification of Local Authorities by the Socio-Economic Level of the Population 2006. 2009, Central Bureau of Statistics, (Accessed 6 march 2011), Israel Central Bureau of Statistics.,
26. Muhsen K, Na'amnih W. Health status of the Arab population in Israel 2008. 2010, Israel Center for Disease Control. Ministry of Health, Publication number 329. (Hebrew).
27. Muhsen K, BaraK M, Henig C, Alpert G, Ornoy A, Cohen D. Is the association between Helicobacter pylori infection and anemia age dependent?. Helicobacter 2010, 15:467-472. 10.1111/j.1523-5378.2010.00793.x, 21083753.
28. Kountouras J, Boziki M, Gavalas E, Zavos C, Deretzi G, Grigoriadis N, Tsolaki M, Chatzopoulos D, Katsinelos P, Tzilves D, Zabouri A, Michailidou I. Increased cerebrospinal fluid Helicobacter pylori antibody in Alzheimer's disease. Int J Neurosci 2009, 119:765-777. 10.1080/00207450902782083, 19326283.
29. Kountouras J, Tsolaki M, Boziki M, Gavalas E, Zavos C, Stergiopoulos C, Kapetanakis N, Chatzopoulos D, Venizelos I. Association between Helicobacter pylori infection and mild cognitive impairment. Eur J Neurol 2007, 14:976-982. 10.1111/j.1468-1331.2007.01827.x, 17718688.
30. Kountouras J, Boziki M, Gavalas E, Zavos C, Grigoriadis N, Deretzi G, Tzilves D, Katsinelos P, Tsolaki M, Chatzopoulos D, Venizelos I. Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer's disease. J Neurol 2009, 256:758-767. 10.1007/s00415-009-5011-z, 19240960.
31. Kountouras J, Gavalas E, Boziki M, Zavos C. Helicobacter pylori may be involved in cognitive impairment and dementia development through induction of atrophic gastritis, vitamin B-12 folate deficiency, and hyperhomocysteinemia sequence. Am J Clin Nutr 2007, 86:805-806.
32. Muhsen K, Athamna A, Bialik A, Alpert G, Cohen D. Presence of Helicobacter pylori in a sibling is associated with a long-term increased risk of H. pylori infection in Israeli Arab children. Helicobacter 2010, 15:108-113. 10.1111/j.1523-5378.2010.00746.x, 20402813.
33. Mendez MA, Adair LS. Severity and timing of stunting in the first two years of life affect performance on cognitive tests in late childhood. J Nutr 1999, 129:1555-1562.