Safety of tranexamic acid in pediatric cardiac surgery: What we do not know

European Journal of Cardio-thoracic Surgery

Volumn 40, Issue 6, 2011, Pages 1550-1551

  Faraoni, David ^a  

^a BRUGMANN UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Antifibrinolytic therapy; Congenital heart disease; Pediatric cardiac surgery; Seizures; Tranexamic acid; Transfusion

Indexed keywords

AMINOCAPROIC ACID; APROTININ; TRANEXAMIC ACID;

DOSE RESPONSE; DRUG SAFETY; HEART SURGERY; HUMAN; KIDNEY FAILURE; KIDNEY INJURY; LETTER; PEDIATRIC SURGERY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RISK ASSESSMENT; SEIZURE;

6-AMINOCAPROIC ACID; ANTIFIBRINOLYTIC AGENTS; CARDIAC SURGICAL PROCEDURES; FEMALE; HUMANS; MALE; POSTOPERATIVE HEMORRHAGE; TRANEXAMIC ACID;

EID: 80955171536     PISSN: 10107940     EISSN: 1873734X     Source Type: Journal    
DOI: 10.1016/j.ejcts.2011.03.009     Document Type: Letter

References (3)

1. Martin K., Breuer T., Gertler R., Hapfelmeier A., Schreiber C., Lange R., Hess J., Wiesner G. Tranexamic acid versus varepsilon-aminocaproic acid: efficacy and safety in paediatric cardiac surgery. Eur J Cardiothorac Surg 2010, 10.1016/j.ejcts.2010.09.041.
2. Schouten E.S., van de Pol A.C., Schouten A.N., Turner N.M., Jansen N.J., Bollen C.W. The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis. Pediatr Crit Care Med 2009, 10:182-190.
3. Breuer T., Martin K., Wilhelm M., Wiesner G., Schreiber C., Hess J., Lange R., Tassani P. The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery. Eur J Cardiothorac Surg 2009, 35:167-171. [author reply 171].