-
1
-
-
79953881831
-
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
-
Anokye-Danso, F., Trivedi, C. M., Juhr, D., Gupta, M., Cui, Z., Tian, Y., Zhang, Y., Yang, W., Gruber, P. J., Epstein, J. A., et al. (2011). Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8, 376-388.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 376-388
-
-
Anokye-Danso, F.1
Trivedi, C.M.2
Juhr, D.3
Gupta, M.4
Cui, Z.5
Tian, Y.6
Zhang, Y.7
Yang, W.8
Gruber, P.J.9
Epstein, J.A.10
-
2
-
-
70349093119
-
Senescence impairs successful reprogramming to pluripotent stem cells
-
Banito, A., Rashid, S. T., Acosta, J. C., Li, S., Pereira, C. F., Geti, I., Pinho, S., Silva, J. C., Azuara, V., Walsh, M., et al. (2009). Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev 23, 2134-2139.
-
(2009)
Genes Dev
, vol.23
, pp. 2134-2139
-
-
Banito, A.1
Rashid, S.T.2
Acosta, J.C.3
Li, S.4
Pereira, C.F.5
Geti, I.6
Pinho, S.7
Silva, J.C.8
Azuara, V.9
Walsh, M.10
-
3
-
-
79959992876
-
Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet Beta cells
-
Bar-Nur, O., Russ, H. A., Efrat, S., and Benvenisty, N. (2011). Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet Beta cells. Cell Stem Cell 9, 17-23.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 17-23
-
-
Bar-Nur, O.1
Russ, H.A.2
Efrat, S.3
Benvenisty, N.4
-
4
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B., Meissner, A., Wernig, M., Plath, K., et al. (2006). A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
5
-
-
53549133376
-
Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells
-
Card, D. A., Hebbar, P. B., Li, L., Trotter, K. W., Komatsu, Y., Mishina, Y., and Archer, T. K. (2008). Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol Cell Biol 28, 6426-6438.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6426-6438
-
-
Card, D.A.1
Hebbar, P.B.2
Li, L.3
Trotter, K.W.4
Komatsu, Y.5
Mishina, Y.6
Archer, T.K.7
-
6
-
-
0038143611
-
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
-
Chambers, I., Colby, D., Robertson, M., Nichols, J., Lee, S., Tweedie, S., and Smith, A. (2003). Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113, 643-655.
-
(2003)
Cell
, vol.113
, pp. 643-655
-
-
Chambers, I.1
Colby, D.2
Robertson, M.3
Nichols, J.4
Lee, S.5
Tweedie, S.6
Smith, A.7
-
7
-
-
37549002155
-
Nanog safeguards pluripotency and mediates germline development
-
Chambers, I., Silva, J., Colby, D., Nichols, J., Nijmeijer, B., Robertson, M., Vrana, J., Jones, K., Grotewold, L., and Smith, A. (2007). Nanog safeguards pluripotency and mediates germline development. Nature 450, 1230-1234.
-
(2007)
Nature
, vol.450
, pp. 1230-1234
-
-
Chambers, I.1
Silva, J.2
Colby, D.3
Nichols, J.4
Nijmeijer, B.5
Robertson, M.6
Vrana, J.7
Jones, K.8
Grotewold, L.9
Smith, A.10
-
8
-
-
0041315884
-
Minicircle DNA vectors devoid of bacterial DNA result in persistent and highlevel transgene expression in vivo
-
Chen, Z. Y., He, C. Y., Ehrhardt, A., and Kay, M. A. (2003). Minicircle DNA vectors devoid of bacterial DNA result in persistent and highlevel transgene expression in vivo. Mol Ther 8, 495-500.
-
(2003)
Mol Ther
, vol.8
, pp. 495-500
-
-
Chen, Z.Y.1
He, C.Y.2
Ehrhardt, A.3
Kay, M.A.4
-
9
-
-
13844292517
-
Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo
-
Chen, Z. Y., He, C. Y., and Kay, M. A. (2005). Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo. Hum Gene Ther 16, 126-131.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 126-131
-
-
Chen, Z.Y.1
He, C.Y.2
Kay, M.A.3
-
10
-
-
23944457397
-
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
-
Cowan, C. A., Atienza, J., Melton, D. A., and Eggan, K. (2005). Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309, 1369-1373.
-
(2005)
Science
, vol.309
, pp. 1369-1373
-
-
Cowan, C.A.1
Atienza, J.2
Melton, D.A.3
Eggan, K.4
-
11
-
-
34249890186
-
Developmental reprogramming after chromosome transfer into mitotic mouse zygotes
-
Egli, D., Rosains, J., Birkhoff, G., and Eggan, K. (2007). Developmental reprogramming after chromosome transfer into mitotic mouse zygotes. Nature 447, 679-685.
-
(2007)
Nature
, vol.447
, pp. 679-685
-
-
Egli, D.1
Rosains, J.2
Birkhoff, G.3
Eggan, K.4
-
12
-
-
69349089552
-
Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells
-
Eminli, S., Foudi, A., Stadtfeld, M., Maherali, N., Ahfeldt, T., Mostoslavsky, G., Hock, H., and Hochedlinger, K. (2009). Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. Nat Genet 41, 968-976.
-
(2009)
Nat Genet
, vol.41
, pp. 968-976
-
-
Eminli, S.1
Foudi, A.2
Stadtfeld, M.3
Maherali, N.4
Ahfeldt, T.5
Mostoslavsky, G.6
Hock, H.7
Hochedlinger, K.8
-
13
-
-
73049112178
-
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
-
Esteban, M. A., Wang, T., Qin, B., Yang, J., Qin, D., Cai, J., Li, W., Weng, Z., Chen, J., Ni, S., et al. (2010). Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 6, 71-79.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 71-79
-
-
Esteban, M.A.1
Wang, T.2
Qin, B.3
Yang, J.4
Qin, D.5
Cai, J.6
Li, W.7
Weng, Z.8
Chen, J.9
Ni, S.10
-
14
-
-
79952258224
-
Somatic coding mutations in human induced pluripotent stem cells
-
Gore, A., Li, Z., Fung, H. L., Young, J. E., Agarwal, S., Antosiewicz-Bourget, J., Canto, I., Giorgetti, A., Israel, M. A., Kiskinis, E., et al. (2011). Somatic coding mutations in human induced pluripotent stem cells. Nature 471, 63-67.
-
(2011)
Nature
, vol.471
, pp. 63-67
-
-
Gore, A.1
Li, Z.2
Fung, H.L.3
Young, J.E.4
Agarwal, S.5
Antosiewicz-Bourget, J.6
Canto, I.7
Giorgetti, A.8
Israel, M.A.9
Kiskinis, E.10
-
15
-
-
66049136895
-
Klf4 reverts developmentally programmed restriction of ground state pluripotency
-
Guo, G., Yang, J., Nichols, J., Hall, J. S., Eyres, I., Mansfield, W., and Smith, A. (2009). Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development 136, 1063-1069.
-
(2009)
Development
, vol.136
, pp. 1063-1069
-
-
Guo, G.1
Yang, J.2
Nichols, J.3
Hall, J.S.4
Eyres, I.5
Mansfield, W.6
Smith, A.7
-
16
-
-
77952699848
-
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
-
Hanna, J., Cheng, A. W., Saha, K., Kim, J., Lengner, C. J., Soldner, F., Cassady, J. P., Muffat, J., Carey, B. W., and Jaenisch, R. (2010a). Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proc Natl Acad Sci U S A, 107, 9222-9227.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 9222-9227
-
-
Hanna, J.1
Cheng, A.W.2
Saha, K.3
Kim, J.4
Lengner, C.J.5
Soldner, F.6
Cassady, J.P.7
Muffat, J.8
Carey, B.W.9
Jaenisch, R.10
-
17
-
-
71449109765
-
Direct cell reprogramming is a stochastic process amenable to acceleration
-
Hanna, J., Saha, K., Pando, B., van Zon, J., Lengner, C. J., Creyghton, M. P., van Oudenaarden, A., and Jaenisch, R. (2009). Direct cell reprogramming is a stochastic process amenable to acceleration. Nature 462, 595-601.
-
(2009)
Nature
, vol.462
, pp. 595-601
-
-
Hanna, J.1
Saha, K.2
Pando, B.3
van Zon, J.4
Lengner, C.J.5
Creyghton, M.P.6
van Oudenaarden, A.7
Jaenisch, R.8
-
18
-
-
78149487692
-
Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues
-
Hanna, J. H., Saha, K., and Jaenisch, R. (2010b). Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 143, 508-525.
-
(2010)
Cell
, vol.143
, pp. 508-525
-
-
Hanna, J.H.1
Saha, K.2
Jaenisch, R.3
-
19
-
-
75349088911
-
The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells
-
Heng, J. C., Feng, B., Han, J., Jiang, J., Kraus, P., Ng, J. H., Orlov, Y. L., Huss, M., Yang, L., Lufkin, T., et al. (2010). The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell 6, 167-174.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 167-174
-
-
Heng, J.C.1
Feng, B.2
Han, J.3
Jiang, J.4
Kraus, P.5
Ng, J.H.6
Orlov, Y.L.7
Huss, M.8
Yang, L.9
Lufkin, T.10
-
20
-
-
53949088050
-
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
-
Heo, I., Joo, C., Cho, J., Ha, M., Han, J., and Kim, V. N. (2008). Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 32, 276-284.
-
(2008)
Mol Cell
, vol.32
, pp. 276-284
-
-
Heo, I.1
Joo, C.2
Cho, J.3
Ha, M.4
Han, J.5
Kim, V.N.6
-
21
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
Hong, H., Takahashi, K., Ichisaka, T., Aoi, T., Kanagawa, O., Nakagawa, M., Okita, K., and Yamanaka, S. (2009). Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460, 1132-1135.
-
(2009)
Nature
, vol.460
, pp. 1132-1135
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
Aoi, T.4
Kanagawa, O.5
Nakagawa, M.6
Okita, K.7
Yamanaka, S.8
-
22
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
-
Huangfu, D., Maehr, R., Guo, W., Eijkelenboom, A., Snitow, M., Chen, A. E., and Melton, D. A. (2008a). Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 26, 795-797.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
Eijkelenboom, A.4
Snitow, M.5
Chen, A.E.6
Melton, D.A.7
-
23
-
-
55749104227
-
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
-
Huangfu, D., Osafune, K., Maehr, R., Guo, W., Eijkelenboom, A., Chen, S., Muhlestein, W., and Melton, D. A. (2008b). Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol 26, 1269-1275.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1269-1275
-
-
Huangfu, D.1
Osafune, K.2
Maehr, R.3
Guo, W.4
Eijkelenboom, A.5
Chen, S.6
Muhlestein, W.7
Melton, D.A.8
-
24
-
-
79952126043
-
Copy number variation and selection during reprogramming to pluripotency
-
Hussein, S. M., Batada, N. N., Vuoristo, S., Ching, R. W., Autio, R., Närvä, E., Ng, S., Sourour, M., Hämäläinen, R., Olsson, C., et al. (2011). Copy number variation and selection during reprogramming to pluripotency. Nature 471, 58-62.
-
(2011)
Nature
, vol.471
, pp. 58-62
-
-
Hussein, S.M.1
Batada, N.N.2
Vuoristo, S.3
Ching, R.W.4
Autio, R.5
Närvä, E.6
Ng, S.7
Sourour, M.8
Hämäläinen, R.9
Olsson, C.10
-
25
-
-
70350536767
-
A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog
-
Ichida, J. K., Blanchard, J., Lam, K., Son, E. Y., Chung, J. E., Egli, D., Loh, K. M., Carter, A. C., Di Giorgio, F. P., Koszka, K., et al. (2009). A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 5, 491-503.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 491-503
-
-
Ichida, J.K.1
Blanchard, J.2
Lam, K.3
Son, E.Y.4
Chung, J.E.5
Egli, D.6
Loh, K.M.7
Carter, A.C.8
Di Giorgio, F.P.9
Koszka, K.10
-
26
-
-
77649275936
-
A nonviral minicircle vector for deriving human iPS cells
-
Jia, F., Wilson, K. D., Sun, N., Gupta, D. M., Huang, M., Li, Z., Panetta, N. J., Chen, Z. Y., Robbins, R. C., Kay, M. A., et al. (2010). A nonviral minicircle vector for deriving human iPS cells. Nat Methods 7, 197-199.
-
(2010)
Nat Methods
, vol.7
, pp. 197-199
-
-
Jia, F.1
Wilson, K.D.2
Sun, N.3
Gupta, D.M.4
Huang, M.5
Li, Z.6
Panetta, N.J.7
Chen, Z.Y.8
Robbins, R.C.9
Kay, M.A.10
-
27
-
-
66149160608
-
Embryonic stem cell-specific microRNAs promote induced pluripotency
-
Judson, R. L., Babiarz, J. E., Venere, M., and Blelloch, R. (2009). Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat Biotechnol 27, 459-461.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 459-461
-
-
Judson, R.L.1
Babiarz, J.E.2
Venere, M.3
Blelloch, R.4
-
28
-
-
64749111225
-
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
-
Kaji, K., Norrby, K., Paca, A., Mileikovsky, M., Mohseni, P., and Woltjen, K. (2009). Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458, 771-775.
-
(2009)
Nature
, vol.458
, pp. 771-775
-
-
Kaji, K.1
Norrby, K.2
Paca, A.3
Mileikovsky, M.4
Mohseni, P.5
Woltjen, K.6
-
29
-
-
78650856128
-
Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors
-
Kane, N. M., Nowrouzi, A., Mukherjee, S., Blundell, M. P., Greig, J. A., Lee, W. K., Houslay, M. D., Milligan, G., Mountford, J. C., von Kalle, C., et al. (2010). Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors. Mol Ther 18, 2139-2145.
-
(2010)
Mol Ther
, vol.18
, pp. 2139-2145
-
-
Kane, N.M.1
Nowrouzi, A.2
Mukherjee, S.3
Blundell, M.P.4
Greig, J.A.5
Lee, W.K.6
Houslay, M.D.7
Milligan, G.8
Mountford, J.C.9
von Kalle, C.10
-
30
-
-
69349100455
-
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
-
Kawamura, T., Suzuki, J., Wang, Y. V., Menendez, S., Morera, L. B., Raya, A., Wahl, G. M., and Belmonte, J. C. (2009). Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 460, 1140-1144.
-
(2009)
Nature
, vol.460
, pp. 1140-1144
-
-
Kawamura, T.1
Suzuki, J.2
Wang, Y.V.3
Menendez, S.4
Morera, L.B.5
Raya, A.6
Wahl, G.M.7
Belmonte, J.C.8
-
31
-
-
66049143859
-
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
-
Kim, D., Kim, C. H., Moon, J. I., Chung, Y. G., Chang, M. Y., Han, B. S., Ko, S., Yang, E., Cha, K. Y., Lanza, R., et al. (2009a). Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4, 472-476.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 472-476
-
-
Kim, D.1
Kim, C.H.2
Moon, J.I.3
Chung, Y.G.4
Chang, M.Y.5
Han, B.S.6
Ko, S.7
Yang, E.8
Cha, K.Y.9
Lanza, R.10
-
32
-
-
40749104852
-
An extended transcriptional network for pluripotency of embryonic stem cells
-
Kim, J., Chu, J., Shen, X., Wang, J., and Orkin, S. H. (2008). An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132, 1049-1061.
-
(2008)
Cell
, vol.132
, pp. 1049-1061
-
-
Kim, J.1
Chu, J.2
Shen, X.3
Wang, J.4
Orkin, S.H.5
-
33
-
-
70349687407
-
Direct reprogramming of human neural stem cells by OCT4
-
Kim, J. B., Greber, B., Araúzo-Bravo, M. J., Meyer, J., Park, K. I., Zaehres, H., and Schöler, H. R. (2009b). Direct reprogramming of human neural stem cells by OCT4. Nature 461, 649-653.
-
(2009)
Nature
, vol.461
, pp. 649-653
-
-
Kim, J.B.1
Greber, B.2
Araúzo-Bravo, M.J.3
Meyer, J.4
Park, K.I.5
Zaehres, H.6
Schöler, H.R.7
-
34
-
-
70649105527
-
Myc's other life: stem cells and beyond
-
Laurenti, E., Wilson, A., and Trumpp, A. (2009). Myc's other life: stem cells and beyond. Curr Opin Cell Biol 21, 844-854.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 844-854
-
-
Laurenti, E.1
Wilson, A.2
Trumpp, A.3
-
35
-
-
69349103956
-
The Ink4/Arf locus is a barrier for iPS cell reprogramming
-
Li, H., Collado, M., Villasante, A., Strati, K., Ortega, S., Cañamero, M., Blasco, M. A., and Serrano, M. (2009). The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 460, 1136-1139.
-
(2009)
Nature
, vol.460
, pp. 1136-1139
-
-
Li, H.1
Collado, M.2
Villasante, A.3
Strati, K.4
Ortega, S.5
Cañamero, M.6
Blasco, M.A.7
Serrano, M.8
-
36
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li, R., Liang, J., Ni, S., Zhou, T., Qing, X., Li, H., He, W., Chen, J., Li, F., Zhuang, Q., et al. (2010). A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7, 51-63.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
Liang, J.2
Ni, S.3
Zhou, T.4
Qing, X.5
Li, H.6
He, W.7
Chen, J.8
Li, F.9
Zhuang, Q.10
-
37
-
-
70350302617
-
Myc-regulated microRNAs attenuate embryonic stem cell differentiation
-
Lin, C. H., Jackson, A. L., Guo, J., Linsley, P. S., and Eisenman, R. N. (2009). Myc-regulated microRNAs attenuate embryonic stem cell differentiation. EMBO J 28, 3157-3170.
-
(2009)
EMBO J
, vol.28
, pp. 3157-3170
-
-
Lin, C.H.1
Jackson, A.L.2
Guo, J.3
Linsley, P.S.4
Eisenman, R.N.5
-
38
-
-
52949125268
-
Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
-
Lin, S. L., Chang, D. C., Chang-Lin, S., Lin, C. H., Wu, D. T., Chen, D. T., and Ying, S. Y. (2008). Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA 14, 2115-2124.
-
(2008)
Rna
, vol.14
, pp. 2115-2124
-
-
Lin, S.L.1
Chang, D.C.2
Chang-Lin, S.3
Lin, C.H.4
Wu, D.T.5
Chen, D.T.6
Ying, S.Y.7
-
39
-
-
79952264847
-
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
-
Lister, R., Pelizzola, M., Kida, Y. S., Hawkins, R. D., Nery, J. R., Hon, G., Antosiewicz-Bourget, J., O'Malley, R., Castanon, R., Klugman, S., et al. (2011). Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 471, 68-73.
-
(2011)
Nature
, vol.471
, pp. 68-73
-
-
Lister, R.1
Pelizzola, M.2
Kida, Y.S.3
Hawkins, R.D.4
Nery, J.R.5
Hon, G.6
Antosiewicz-Bourget, J.7
O'Malley, R.8
Castanon, R.9
Klugman, S.10
-
40
-
-
79958292714
-
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
-
Maekawa, M., Yamaguchi, K., Nakamura, T., Shibukawa, R., Kodanaka, I., Ichisaka, T., Kawamura, Y., Mochizuki, H., Goshima, N., and Yamanaka, S. (2011). Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Nature 474, 225-229.
-
(2011)
Nature
, vol.474
, pp. 225-229
-
-
Maekawa, M.1
Yamaguchi, K.2
Nakamura, T.3
Shibukawa, R.4
Kodanaka, I.5
Ichisaka, T.6
Kawamura, Y.7
Mochizuki, H.8
Goshima, N.9
Yamanaka, S.10
-
41
-
-
70350571742
-
Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc
-
Maherali, N., and Hochedlinger, K. (2009). Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc. Curr Biol 19, 1718-1723.
-
(2009)
Curr Biol
, vol.19
, pp. 1718-1723
-
-
Maherali, N.1
Hochedlinger, K.2
-
42
-
-
48749109906
-
Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts
-
Mali, P., Ye, Z., Hommond, H. H., Yu, X., Lin, J., Chen, G., Zou, J., and Cheng, L. (2008). Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts. Stem Cells 26, 1998-2005.
-
(2008)
Stem Cells
, vol.26
, pp. 1998-2005
-
-
Mali, P.1
Ye, Z.2
Hommond, H.H.3
Yu, X.4
Lin, J.5
Chen, G.6
Zou, J.7
Cheng, L.8
-
43
-
-
69349094006
-
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
-
Marión, R. M., Strati, K., Li, H., Murga, M., Blanco, R., Ortega, S., Fernandez-Capetillo, O., Serrano, M., and Blasco, M. A. (2009). A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature 460, 1149-1153.
-
(2009)
Nature
, vol.460
, pp. 1149-1153
-
-
Marión, R.M.1
Strati, K.2
Li, H.3
Murga, M.4
Blanco, R.5
Ortega, S.6
Fernandez-Capetillo, O.7
Serrano, M.8
Blasco, M.A.9
-
44
-
-
34249876564
-
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
-
Masui, S., Nakatake, Y., Toyooka, Y., Shimosato, D., Yagi, R., Takahashi, K., Okochi, H., Okuda, A., Matoba, R., Sharov, A. A., et al. (2007). Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 9, 625-635.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 625-635
-
-
Masui, S.1
Nakatake, Y.2
Toyooka, Y.3
Shimosato, D.4
Yagi, R.5
Takahashi, K.6
Okochi, H.7
Okuda, A.8
Matoba, R.9
Sharov, A.A.10
-
45
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen, T. S., Hanna, J., Zhang, X., Ku, M., Wernig, M., Schorderet, P., Bernstein, B. E., Jaenisch, R., Lander, E. S., and Meissner, A. (2008). Dissecting direct reprogramming through integrative genomic analysis. Nature 454, 49-55.
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
Ku, M.4
Wernig, M.5
Schorderet, P.6
Bernstein, B.E.7
Jaenisch, R.8
Lander, E.S.9
Meissner, A.10
-
46
-
-
79957855262
-
Reprogramming of mouse and human cells to pluripotency using mature microRNAs
-
Miyoshi, N., Ishii, H., Nagano, H., Haraguchi, N., Dewi, D. L., Kano, Y., Nishikawa, S., Tanemura, M., Mimori, K., Tanaka, F., et al. (2011). Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell 8, 633-638.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 633-638
-
-
Miyoshi, N.1
Ishii, H.2
Nagano, H.3
Haraguchi, N.4
Dewi, D.L.5
Kano, Y.6
Nishikawa, S.7
Tanemura, M.8
Mimori, K.9
Tanaka, F.10
-
47
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa, M., Koyanagi, M., Tanabe, K., Takahashi, K., Ichisaka, T., Aoi, T., Okita, K., Mochiduki, Y., Takizawa, N., and Yamanaka, S. (2008). Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26, 101-106.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
Takahashi, K.4
Ichisaka, T.5
Aoi, T.6
Okita, K.7
Mochiduki, Y.8
Takizawa, N.9
Yamanaka, S.10
-
48
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D., Chambers, I., Schöler, H., and Smith, A. (1998). Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95, 379-391.
-
(1998)
Cell
, vol.95
, pp. 379-391
-
-
Nichols, J.1
Zevnik, B.2
Anastassiadis, K.3
Niwa, H.4
Klewe-Nebenius, D.5
Chambers, I.6
Schöler, H.7
Smith, A.8
-
49
-
-
67650032868
-
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
-
Niwa, H., Ogawa, K., Shimosato, D., and Adachi, K. (2009). A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells. Nature 460, 118-122.
-
(2009)
Nature
, vol.460
, pp. 118-122
-
-
Niwa, H.1
Ogawa, K.2
Shimosato, D.3
Adachi, K.4
-
50
-
-
77949881949
-
An expanded Oct4 interaction network: implications for stem cell biology, development, and disease
-
Pardo, M., Lang, B., Yu, L., Prosser, H., Bradley, A., Babu, M. M., and Choudhary, J. (2010). An expanded Oct4 interaction network: implications for stem cell biology, development, and disease. Cell Stem Cell 6, 382-395.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 382-395
-
-
Pardo, M.1
Lang, B.2
Yu, L.3
Prosser, H.4
Bradley, A.5
Babu, M.M.6
Choudhary, J.7
-
51
-
-
78651254192
-
Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach
-
Plews, J. R., Li, J., Jones, M., Moore, H. D., Mason, C., Andrews, P. W., and Na, J. (2010). Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach. PLoS One 5, e14397.
-
(2010)
PLoS One
, vol.5
-
-
Plews, J.R.1
Li, J.2
Jones, M.3
Moore, H.D.4
Mason, C.5
Andrews, P.W.6
Na, J.7
-
52
-
-
52949091534
-
The let-7 family of microRNAs
-
Roush, S., and Slack, F. J. (2008). The let-7 family of microRNAs. Trends Cell Biol 18, 505-516.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 505-516
-
-
Roush, S.1
Slack, F.J.2
-
53
-
-
44349103591
-
A combined chemical and genetic approach for the generation of induced pluripotent stem cells
-
Shi, Y., Do, J. T., Desponts, C., Hahm, H. S., Schöler, H. R., and Ding, S. (2008). A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2, 525-528.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 525-528
-
-
Shi, Y.1
Do, J.T.2
Desponts, C.3
Hahm, H.S.4
Schöler, H.R.5
Ding, S.6
-
54
-
-
54949105021
-
Promotion of reprogramming to ground state pluripotency by signal inhibition
-
Silva, J., Barrandon, O., Nichols, J., Kawaguchi, J., Theunissen, T. W., and Smith, A. (2008). Promotion of reprogramming to ground state pluripotency by signal inhibition. PLoS Biol 6, e253.
-
(2008)
PLoS Biol
, vol.6
-
-
Silva, J.1
Barrandon, O.2
Nichols, J.3
Kawaguchi, J.4
Theunissen, T.W.5
Smith, A.6
-
55
-
-
2942534403
-
Human embryonic stem cells express a unique set of microRNAs
-
Suh, M. R., Lee, Y., Kim, J. Y., Kim, S. K., Moon, S. H., Lee, J. Y., Cha, K. Y., Chung, H. M., Yoon, H. S., Moon, S. Y., et al. (2004). Human embryonic stem cells express a unique set of microRNAs. Dev Biol 270, 488-498.
-
(2004)
Dev Biol
, vol.270
, pp. 488-498
-
-
Suh, M.R.1
Lee, Y.2
Kim, J.Y.3
Kim, S.K.4
Moon, S.H.5
Lee, J.Y.6
Cha, K.Y.7
Chung, H.M.8
Yoon, H.S.9
Moon, S.Y.10
-
56
-
-
2342471959
-
Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector
-
Szymczak, A. L., Workman, C. J., Wang, Y., Vignali, K. M., Dilioglou, S., Vanin, E. F., and Vignali, D. A. (2004). Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector. Nat Biotechnol 22, 589-594.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 589-594
-
-
Szymczak, A.L.1
Workman, C.J.2
Wang, Y.3
Vignali, K.M.4
Dilioglou, S.5
Vanin, E.F.6
Vignali, D.A.7
-
57
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
58
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K., and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
59
-
-
28644443829
-
Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells
-
Taranger, C. K., Noer, A., Sørensen, A. L., Håkelien, A. M., Boquest, A. C., and Collas, P. (2005). Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells. Mol Biol Cell 16, 5719-5735.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 5719-5735
-
-
Taranger, C.K.1
Noer, A.2
Sørensen, A.L.3
Håkelien, A.M.4
Boquest, A.C.5
Collas, P.6
-
60
-
-
77956214743
-
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
-
Urbach, A., Bar-Nur, O., Daley, G. Q., and Benvenisty, N. (2010). Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell 6, 407-411.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 407-411
-
-
Urbach, A.1
Bar-Nur, O.2
Daley, G.Q.3
Benvenisty, N.4
-
61
-
-
70350380887
-
Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells
-
Utikal, J., Maherali, N., Kulalert, W., and Hochedlinger, K. (2009a). Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. J Cell Sci 122, 3502-3510.
-
(2009)
J Cell Sci
, vol.122
, pp. 3502-3510
-
-
Utikal, J.1
Maherali, N.2
Kulalert, W.3
Hochedlinger, K.4
-
62
-
-
69349098273
-
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
-
Utikal, J., Polo, J. M., Stadtfeld, M., Maherali, N., Kulalert, W., Walsh, R. M., Khalil, A., Rheinwald, J. G., and Hochedlinger, K. (2009b). Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature 460, 1145-1148.
-
(2009)
Nature
, vol.460
, pp. 1145-1148
-
-
Utikal, J.1
Polo, J.M.2
Stadtfeld, M.3
Maherali, N.4
Kulalert, W.5
Walsh, R.M.6
Khalil, A.7
Rheinwald, J.G.8
Hochedlinger, K.9
-
63
-
-
40849108663
-
Selective blockade of microRNA processing by Lin28
-
Viswanathan, S. R., Daley, G. Q., and Gregory, R. I. (2008). Selective blockade of microRNA processing by Lin28. Science 320, 97-100.
-
(2008)
Science
, vol.320
, pp. 97-100
-
-
Viswanathan, S.R.1
Daley, G.Q.2
Gregory, R.I.3
-
64
-
-
33751092246
-
A protein interaction network for pluripotency of embryonic stem cells
-
Wang, J., Rao, S., Chu, J., Shen, X., Levasseur, D. N., Theunissen, T. W., and Orkin, S. H. (2006). A protein interaction network for pluripotency of embryonic stem cells. Nature 444, 364-368.
-
(2006)
Nature
, vol.444
, pp. 364-368
-
-
Wang, J.1
Rao, S.2
Chu, J.3
Shen, X.4
Levasseur, D.N.5
Theunissen, T.W.6
Orkin, S.H.7
-
65
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
Warren, L., Manos, P. D., Ahfeldt, T., Loh, Y. H., Li, H., Lau, F., Ebina, W., Mandal, P. K., Smith, Z. D., Meissner, A., et al. (2010). Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7, 618-630.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
Loh, Y.H.4
Li, H.5
Lau, F.6
Ebina, W.7
Mandal, P.K.8
Smith, Z.D.9
Meissner, A.10
-
66
-
-
0031044215
-
Viable offspring derived from fetal and adult mammalian cells
-
Wilmut, I., Schnieke, A. E., McWhir, J., Kind, A. J., and Campbell, K. H. (1997). Viable offspring derived from fetal and adult mammalian cells. Nature 385, 810-813.
-
(1997)
Nature
, vol.385
, pp. 810-813
-
-
Wilmut, I.1
Schnieke, A.E.2
McWhir, J.3
Kind, A.J.4
Campbell, K.H.5
-
67
-
-
64749083939
-
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
Woltjen, K., Michael, I. P., Mohseni, P., Desai, R., Mileikovsky, M., Hämäläinen, R., Cowling, R., Wang, W., Liu, P., Gertsenstein, M., et al. (2009). piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766-770.
-
(2009)
Nature
, vol.458
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
Desai, R.4
Mileikovsky, M.5
Hämäläinen, R.6
Cowling, R.7
Wang, W.8
Liu, P.9
Gertsenstein, M.10
-
68
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
Yu, J., Hu, K., Smuga-Otto, K., Tian, S., Stewart, R., Slukvin, I. I., and Thomson, J. A. (2009). Human induced pluripotent stem cells free of vector and transgene sequences. Science 324, 797-801.
-
(2009)
Science
, vol.324
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otto, K.3
Tian, S.4
Stewart, R.5
Slukvin, I.I.6
Thomson, J.A.7
-
69
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu, J., Vodyanik, M. A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J. L., Tian, S., Nie, J., Jonsdottir, G. A., Ruotti, V., Stewart, R., et al. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science, 318, 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
-
70
-
-
65449154892
-
Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
-
Yusa, K., Rad, R., Takeda, J., and Bradley, A. (2009). Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon. Nat Methods 6, 363-369.
-
(2009)
Nat Methods
, vol.6
, pp. 363-369
-
-
Yusa, K.1
Rad, R.2
Takeda, J.3
Bradley, A.4
-
71
-
-
79957807595
-
Immunogenicity of induced pluripotent stem cells
-
Zhao, T., Zhang, Z. N., Rong, Z., and Xu, Y. (2011). Immunogenicity of induced pluripotent stem cells. Nature 474, 212-215.
-
(2011)
Nature
, vol.474
, pp. 212-215
-
-
Zhao, T.1
Zhang, Z.N.2
Rong, Z.3
Xu, Y.4
-
72
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Zhao, Y., Yin, X., Qin, H., Zhu, F., Liu, H., Yang, W., Zhang, Q., Xiang, C., Hou, P., Song, Z., et al. (2008a). Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cell 3, 475-479.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 475-479
-
-
Zhao, Y.1
Yin, X.2
Qin, H.3
Zhu, F.4
Liu, H.5
Yang, W.6
Zhang, Q.7
Xiang, C.8
Hou, P.9
Song, Z.10
-
73
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Zhao, Y., Yin, X., Qin, H., Zhu, F., Liu, H., Yang, W., Zhang, Q., Xiang, C., Hou, P., Song, Z., et al. (2008b). Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cell 3, 475-479.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 475-479
-
-
Zhao, Y.1
Yin, X.2
Qin, H.3
Zhu, F.4
Liu, H.5
Yang, W.6
Zhang, Q.7
Xiang, C.8
Hou, P.9
Song, Z.10
-
74
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
Zhou, H., Wu, S., Joo, J. Y., Zhu, S., Han, D. W., Lin, T., Trauger, S., Bien, G., Yao, S., Zhu, Y., et al. (2009). Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4, 381-384.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
Zhu, S.4
Han, D.W.5
Lin, T.6
Trauger, S.7
Bien, G.8
Yao, S.9
Zhu, Y.10
-
75
-
-
78649647814
-
Reprogramming of human primary somatic cells by OCT4 and chemical compounds
-
Zhu, S., Li, W., Zhou, H., Wei, W., Ambasudhan, R., Lin, T., Kim, J., Zhang, K., and Ding, S. (2010). Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell 7, 651-655.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 651-655
-
-
Zhu, S.1
Li, W.2
Zhou, H.3
Wei, W.4
Ambasudhan, R.5
Lin, T.6
Kim, J.7
Zhang, K.8
Ding, S.9
|