Functional analysis of SGR4635-induced enhancement of pigmented antibiotic production in Streptomyces lividans

Journal of Microbiology

Volumn 49, Issue 5, 2011, Pages 828-833

  Chi, Won Jae ^a   Lee, Soon Youl ^b   Lee, JaeHag ^c  

^a Myong Ji University   (South Korea)

^b Hankyong National University   (South Korea)

^c Seoil University   (South Korea)

Author keywords

antibiotic production; DasR; N acetylglucosamine; Streptomyces; transcriptional regulator

Indexed keywords

ACTINORHODINE; ANTHRAQUINONE DERIVATIVE; ANTIINFECTIVE AGENT; CARRIER PROTEIN; DRUG DERIVATIVE; N ACETYLGLUCOSAMINE; PRODIGIOSIN; RECOMBINANT PROTEIN; UNDECYLPRODIGIOSIN;

ARTICLE; BIOSYNTHESIS; ENZYMOLOGY; GENETICS; METABOLISM; STREPTOMYCES GRISEUS; STREPTOMYCES LIVIDANS;

ACETYLGLUCOSAMINE; ANTHRAQUINONES; ANTI-BACTERIAL AGENTS; MEMBRANE TRANSPORT PROTEINS; PRODIGIOSIN; RECOMBINANT PROTEINS; STREPTOMYCES GRISEUS; STREPTOMYCES LIVIDANS;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOMYCES; STREPTOMYCES COELICOLOR; STREPTOMYCES GRISEUS; STREPTOMYCES LIVIDANS;

EID: 80955131406     PISSN: 12258873     EISSN: 19763794     Source Type: Journal    
DOI: 10.1007/s12275-011-1100-7     Document Type: Article

References (22)

1. Bentley, S. D., K. F. Chater, A. M. Cerdeno-Tárraga, G. L. Challis, N. R. Thomson, K. D. James, D. E. Harris, and et al. 2002. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417, 141-147.
2. Bibb, M. J. 2005. Regulation of secondary metabolism in Streptomycetes. Curr. Opin. Microbiol. 8, 208-215.
3. Chater, K. F. and S. Horinouchi. 2003. Signaling early developmental events in two highly diverged Streptomyces species. Mol. Microbiol. 48, 9-15.
4. Chi, W. J., X. M. Jin, S. C. Jung, E. A. Oh, and S. K. Hong. 2011. Characterization of Sgr3394 produced only by the A-Factor-producing Streptomyces griseus IFO13350, not by the A-Factor deficient mutant HH1. J. Microbiol. 49, 155-160.
5. Colson, S., J. Stephan, T. Hertrich, A. Saito, G. P. h van Wezel, F. Titgemeyer, and S. Rigali. 2006. Conserved cis-acting elements upstream of genes composing the chitinolytic system of Streptomycetes are DasR-responsive elements. J. Mol. Microbiol. Biotechnol. 12, 60-66.
6. Fernandez, M. and J. Sanchez. 2002. Nuclease activities and cell death processes associated with the development of surface cultures of Streptomyces antbioticus ETH7451. Microbiology 148, 405-412.
7. Hong, S. K., A. Matsumoto, S. Horinouchi, and T. Beppu. 1993. Effects of protein kinase inhibitors on in vitro protein phosphorylation and cellular differentiation of Streptomyces griseus. Mol. Gen. Genet. 236, 347-354.
8. Hopwood, D. A., M. J. Bibb, K. J. Chater, T. Kieser, C. J. Bruton, H. M. Kieser, D. J. Lydiate, C. P. Smith, J. M. Ward, and H. Schrempf. 1985. Genetic manipulation of Streptomyces: a laboratory manual. The John Innes Foundation, Norwich, England.
9. Horinouchi, S. 2002. A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus. Front. Biosci. 7, 2045-2057.
10. Horinouchi, S. 2007. Mining and polishing of the treasure trove in the bacterial genus Streptomyces. Biosci. Biotechnol. Biochem. 71, 283-299.
11. Horinouchi, S. and T. Beppu. 1994. A-factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus. Mol. Microbiol. 12, 859-864.
12. Horinouchi, S., Y. Kumada, and T. Beppu. 1984. Unstable genetic determinant of A-factor biosynthesis in streptomycin-producing organisms: cloning and characterization. J. Bacteriol. 158, 481-487.
13. Kato, J. Y., W. J. Chi, Y. Ohnishi, S. K. Hong, and S. Horinouchi. 2005. Transcriptional control by A-factor of two trypsin genes in Streptomyces griseus. J. Bacteriol. 187, 286-295.
14. Kim, E. S., H. J. Hong, C. Y. Choi, and N. Cohen. 2001. Modulation of actinorhodin biosynthesis in Streptomyces lividans by glucose repression of afsR2 gene transcription. J. Bacteriol. 183, 2198-2203.
15. Kim, Y. J., S. O. Sa, Y. K. Chang, S. K. Hong, and Y. S. Hong. 2007. Overexpression of Shinorhzobium meliloti hemoprotein in Streptomyces lividans to enhance secondary metabolite production. J. Microbiol. Biotechnol. 17, 2066-2070.
16. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, NY, USA.
17. Manteca, A., R. Alvarez, N. Salazar, P. Yagüe, and J. Sanchez. 2008. Mycelium differentiation and antibiotic production in submerged cultures of Streptomyces coelicolor. Appl. Environ. Microbiol. 74, 3877-3886.
18. Nothaft, H., S. Rigali, B. Boomsma, M. Swiatek, K. J. McDowall, G. P. van Wezel, and F. Titgemeyer. 2010. The permease gene nagE2 is the key to N-acetylglucosamine sensing and utilization in Streptomyces coelicolor and is subject to multi-level control. Mol. Microbiol. 75, 1133-1144.
19. Rigali, S., H. Nothaft, E. E. E. Noens, M. Schlicht, S. Colson, M. Müller, B. Joris, and et al. 2006. The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development. Mol. Microbiol. 61, 1237-1257.
20. Rigali, S., F. Titgemeyer, S. Barends, S. Mulder, A. W. Thomae, D. A. Hopwood, and G. P. van Wezel. 2008. Feast of famine: the global regulator DasR links nutrient stress to antibiotic production by Strepotmyces. EMBO Reports 9, 670-675.
21. Sambrook, J. and D. W. Russell. 2001. Molecular Cloning: A Laboratory Manual, 3rd (ed.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, NY, USA.
22. Seo, J. W., Y. Ohnishi, A. Hirata, and S. Horinouchi. 2002. ATP-binding cassette transport system involved in regulation of morphological differentiation in response to glucose in Streptomyces griseus. J. Bacteriol. 184, 91-103.