메뉴 건너뛰기




Volumn 15, Issue 6, 2011, Pages 941-952

PTH(1-34)-induced changes in RANKL and OPG expression by human PDL cells modify osteoclast biology in a co-culture model with RAW 264.7 cells

Author keywords

Co culture of human PDL cells and RAW cells; In vitro; Intermittent PTH(1 34); Osteoclasts biology; Osteoprotegerin; RANKL

Indexed keywords

ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CATHEPSIN K; ISOENZYME; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PARATHYROID HORMONE; TARTRATE-RESISTANT ACID PHOSPHATASE; TNFRSF11B PROTEIN, HUMAN; TNFSF11 PROTEIN, HUMAN; VITRONECTIN RECEPTOR;

EID: 80955130003     PISSN: 14326981     EISSN: 14363771     Source Type: Journal    
DOI: 10.1007/s00784-010-0456-0     Document Type: Article
Times cited : (41)

References (52)
  • 1
    • 34247392923 scopus 로고    scopus 로고
    • Gingival crevicular fluid levels of RANKL and OPG in periodontal diseases: implications of their relative ratio
    • Bostanci N, Ilgenli T, Emingil G et al (2007) Gingival crevicular fluid levels of RANKL and OPG in periodontal diseases: implications of their relative ratio. J Clin Periodontol 34: 370-376.
    • (2007) J Clin Periodontol , vol.34 , pp. 370-376
    • Bostanci, N.1    Ilgenli, T.2    Emingil, G.3
  • 2
    • 33846091717 scopus 로고    scopus 로고
    • (2007) Roles of receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoprotegerin in periodontal health and disease
    • Nagasawa T, Kiji M, Yashiro R et al (2000) (2007) Roles of receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoprotegerin in periodontal health and disease. Periodontol 43: 65-84.
    • (2000) Periodontol , vol.43 , pp. 65-84
    • Nagasawa, T.1    Kiji, M.2    Yashiro, R.3
  • 3
    • 33748549017 scopus 로고    scopus 로고
    • Identification of the osteoprotegerin/receptor activator of nuclear factor-kappa B ligand system in gingival crevicular fluid and tissue of patients with chronic periodontitis
    • Lu HK, Chen YL, Chang HC et al (2006) Identification of the osteoprotegerin/receptor activator of nuclear factor-kappa B ligand system in gingival crevicular fluid and tissue of patients with chronic periodontitis. J Periodontal Res 41: 354-360.
    • (2006) J Periodontal Res , vol.41 , pp. 354-360
    • Lu, H.K.1    Chen, Y.L.2    Chang, H.C.3
  • 4
    • 34247574199 scopus 로고    scopus 로고
    • Regulation of RANKL and OPG gene expression in human gingival fibroblasts and periodontal ligament cells by Porphyromonas gingivalis: a putative role of the Arg-gingipains
    • Belibasakis G, Bostanci N, Hashim A et al (2007) Regulation of RANKL and OPG gene expression in human gingival fibroblasts and periodontal ligament cells by Porphyromonas gingivalis: a putative role of the Arg-gingipains. Microb Pathog 43: 46-53.
    • (2007) Microb Pathog , vol.43 , pp. 46-53
    • Belibasakis, G.1    Bostanci, N.2    Hashim, A.3
  • 5
    • 33750485771 scopus 로고    scopus 로고
    • Cytokine production in human periodontal ligament cells stimulated with Porphyromonas gingivalis
    • Yamamoto T, Kita M, Oseko F et al (2006) Cytokine production in human periodontal ligament cells stimulated with Porphyromonas gingivalis. J Periodontal Res 41: 554-559.
    • (2006) J Periodontal Res , vol.41 , pp. 554-559
    • Yamamoto, T.1    Kita, M.2    Oseko, F.3
  • 6
    • 33947306303 scopus 로고    scopus 로고
    • Effect of smoking on serum RANKL and OPG in sex, age and clinically matched supportive-therapy periodontitis patients
    • Lappin DF, Sherrabeh S, Jenkins WM et al (2007) Effect of smoking on serum RANKL and OPG in sex, age and clinically matched supportive-therapy periodontitis patients. J Clin Periodontol 34: 271-277.
    • (2007) J Clin Periodontol , vol.34 , pp. 271-277
    • Lappin, D.F.1    Sherrabeh, S.2    Jenkins, W.M.3
  • 7
    • 33745586626 scopus 로고    scopus 로고
    • Levels of RANKL and OPG in gingival crevicular fluid during orthodontic tooth movement and effect of compression force on releases from periodontal ligament cells in vitro
    • Nishijima Y, Yamaguchi M, Kojima T et al (2006) Levels of RANKL and OPG in gingival crevicular fluid during orthodontic tooth movement and effect of compression force on releases from periodontal ligament cells in vitro. Orthod Craniofac Res 9: 63-70.
    • (2006) Orthod Craniofac Res , vol.9 , pp. 63-70
    • Nishijima, Y.1    Yamaguchi, M.2    Kojima, T.3
  • 8
    • 33748080101 scopus 로고    scopus 로고
    • RANKL increase in compressed periodontal ligament cells from root resorption
    • Yamaguchi M, Aihara N, Kojima T et al (2006) RANKL increase in compressed periodontal ligament cells from root resorption. J Dent Res 85: 751-756.
    • (2006) J Dent Res , vol.85 , pp. 751-756
    • Yamaguchi, M.1    Aihara, N.2    Kojima, T.3
  • 9
    • 33645769738 scopus 로고    scopus 로고
    • Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement
    • Kanzaki H, Chiba M, Arai K et al (2006) Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement. Gene Ther 13: 678-685.
    • (2006) Gene Ther , vol.13 , pp. 678-685
    • Kanzaki, H.1    Chiba, M.2    Arai, K.3
  • 10
    • 16544394019 scopus 로고    scopus 로고
    • Local OPG gene transfer to periodontal tissue inhibits orthodontic tooth movement
    • Kanzaki H, Chiba M, Takahashi I et al (2004) Local OPG gene transfer to periodontal tissue inhibits orthodontic tooth movement. J Dent Res 83: 920-925.
    • (2004) J Dent Res , vol.83 , pp. 920-925
    • Kanzaki, H.1    Chiba, M.2    Takahashi, I.3
  • 11
    • 43049138412 scopus 로고    scopus 로고
    • Cultured human periodontal ligament cells constitutively express multiple osteotropic cytokines and growth factors, several of which are responsive to mechanical deformation
    • Pinkerton MN, Wescott DC, Gaffey BJ et al (2008) Cultured human periodontal ligament cells constitutively express multiple osteotropic cytokines and growth factors, several of which are responsive to mechanical deformation. J Periodontal Res 43: 343-351.
    • (2008) J Periodontal Res , vol.43 , pp. 343-351
    • Pinkerton, M.N.1    Wescott, D.C.2    Gaffey, B.J.3
  • 12
    • 0035008944 scopus 로고    scopus 로고
    • Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition
    • Kanzaki H, Chiba M, Shimizu Y et al (2001) Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition. J Dent Res 80: 887-891.
    • (2001) J Dent Res , vol.80 , pp. 887-891
    • Kanzaki, H.1    Chiba, M.2    Shimizu, Y.3
  • 13
    • 23944486767 scopus 로고    scopus 로고
    • PTH(1-34) affects osteoprotegerin production in human PDL cells in vitro
    • Lossdorfer S, Gotz W, Jager A (2005) PTH(1-34) affects osteoprotegerin production in human PDL cells in vitro. J Dent Res 84: 634-638.
    • (2005) J Dent Res , vol.84 , pp. 634-638
    • Lossdorfer, S.1    Gotz, W.2    Jager, A.3
  • 14
    • 0036886956 scopus 로고    scopus 로고
    • Expression of receptor activator of NF-kappa B ligand and osteoprotegerin in culture of human periodontal ligament cells
    • Hasegawa T, Yoshimura Y, Kikuiri T et al (2002) Expression of receptor activator of NF-kappa B ligand and osteoprotegerin in culture of human periodontal ligament cells. J Periodontal Res 37: 405-411.
    • (2002) J Periodontal Res , vol.37 , pp. 405-411
    • Hasegawa, T.1    Yoshimura, Y.2    Kikuiri, T.3
  • 15
    • 0035287948 scopus 로고    scopus 로고
    • Participation of periodontal ligament cells with regeneration of alveolar bone
    • Isaka J, Ohazama A, Kobayashi M et al (2001) Participation of periodontal ligament cells with regeneration of alveolar bone. J Periodontol 72: 314-323.
    • (2001) J Periodontol , vol.72 , pp. 314-323
    • Isaka, J.1    Ohazama, A.2    Kobayashi, M.3
  • 16
    • 0037205333 scopus 로고    scopus 로고
    • Culturing and characterization of human periodontal ligament fibroblasts-a preliminary study
    • Chou AM, Sae-Lim V, Lim T et al (2002) Culturing and characterization of human periodontal ligament fibroblasts-a preliminary study. Mater Sci Eng 20: 77-83.
    • (2002) Mater Sci Eng , vol.20 , pp. 77-83
    • Chou, A.M.1    Sae-Lim, V.2    Lim, T.3
  • 17
    • 0031303339 scopus 로고    scopus 로고
    • Osteoblast-like properties of human periodontal l igament cells: an in vitro analysis
    • Basdra EK, Komposch G (1997) Osteoblast-like properties of human periodontal l igament cells: an in vitro analysis. Eur J Orthod 19: 615-621.
    • (1997) Eur J Orthod , vol.19 , pp. 615-621
    • Basdra, E.K.1    Komposch, G.2
  • 18
    • 27744473858 scopus 로고    scopus 로고
    • Parathyroid-hormone-related protein induces expression of receptor activator of NF-{kappa}B ligand in human periodontal ligament cells via a cAMP/protein kinase A-independent pathway
    • Fukushima H, Jimi E, Kajiya H et al (2005) Parathyroid-hormone-related protein induces expression of receptor activator of NF-{kappa}B ligand in human periodontal ligament cells via a cAMP/protein kinase A-independent pathway. J Dent Res 84: 329-334.
    • (2005) J Dent Res , vol.84 , pp. 329-334
    • Fukushima, H.1    Jimi, E.2    Kajiya, H.3
  • 19
    • 0842289106 scopus 로고    scopus 로고
    • The expression of osteoprotegerin and the receptor activator of nuclear factor kappa B ligand in human periodontal ligament cells cultured with and without 1alpha, 25-dihydroxyvitamin D3
    • Zhang D, Yang YQ, Li XT et al (2004) The expression of osteoprotegerin and the receptor activator of nuclear factor kappa B ligand in human periodontal ligament cells cultured with and without 1alpha, 25-dihydroxyvitamin D3. Arch Oral Biol 49: 71-76.
    • (2004) Arch Oral Biol , vol.49 , pp. 71-76
    • Zhang, D.1    Yang, Y.Q.2    Li, X.T.3
  • 20
    • 0003508906 scopus 로고    scopus 로고
    • Pulsatile parathyroid hormone (PTH) treatment increases bone formation in vitro in fetal rat calvarial cell (FRCC) culture system
    • Yang ZJ, Cheng V, Barnes S et al (1997) Pulsatile parathyroid hormone (PTH) treatment increases bone formation in vitro in fetal rat calvarial cell (FRCC) culture system. J Bone Miner Res 12(Suppl 1): S317.
    • (1997) J Bone Miner Res , vol.12 , Issue.SUPPL. 1
    • Yang, Z.J.1    Cheng, V.2    Barnes, S.3
  • 21
    • 0029041148 scopus 로고
    • A small dose of human parathyroid hormone(1-34) increased bone mass in the lumbar vertebrae in patients with senile osteoporosis
    • Sone T, Fukunaga M, Ono S et al (1995) A small dose of human parathyroid hormone(1-34) increased bone mass in the lumbar vertebrae in patients with senile osteoporosis. Miner Electrolyte Metab 21: 232-235.
    • (1995) Miner Electrolyte Metab , vol.21 , pp. 232-235
    • Sone, T.1    Fukunaga, M.2    Ono, S.3
  • 22
    • 33750437214 scopus 로고    scopus 로고
    • Parathyroid hormone modifies human periodontal ligament cell proliferation and survival in vitro
    • Lossdorfer S, Gotz W, Jager A (2006) Parathyroid hormone modifies human periodontal ligament cell proliferation and survival in vitro. J Periodontal Res 41: 519-526.
    • (2006) J Periodontal Res , vol.41 , pp. 519-526
    • Lossdorfer, S.1    Gotz, W.2    Jager, A.3
  • 23
    • 33645059992 scopus 로고    scopus 로고
    • Maturation-state dependent response of human periodontal ligament cells to an intermittent parathyroid hormone exposure in vitro
    • Lossdorfer S, Stier S, Gotz W et al (2006) Maturation-state dependent response of human periodontal ligament cells to an intermittent parathyroid hormone exposure in vitro. J Periodontal Res 41: 62-72.
    • (2006) J Periodontal Res , vol.41 , pp. 62-72
    • Lossdorfer, S.1    Stier, S.2    Gotz, W.3
  • 24
    • 0042659529 scopus 로고    scopus 로고
    • Von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation
    • Bonewald LF, Harris SE, Rosser J et al (2003) Von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation. Calcif Tissue Int 72: 537-547.
    • (2003) Calcif Tissue Int , vol.72 , pp. 537-547
    • Bonewald, L.F.1    Harris, S.E.2    Rosser, J.3
  • 25
    • 0029851956 scopus 로고    scopus 로고
    • Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis
    • Hayman AR, Jones SJ, Boyde A et al (1996) Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis. Development 122: 3151-3162.
    • (1996) Development , vol.122 , pp. 3151-3162
    • Hayman, A.R.1    Jones, S.J.2    Boyde, A.3
  • 26
    • 0028831635 scopus 로고
    • Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone
    • Inaoka T, Bilbe G, Ishibashi O et al (1995) Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone. Biochem Biophys Res Commun 206: 89-96.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 89-96
    • Inaoka, T.1    Bilbe, G.2    Ishibashi, O.3
  • 28
    • 70350423467 scopus 로고    scopus 로고
    • CCR5 down-regulates osteoclast function in orthodontic tooth movement
    • Andrade I Jr, Taddei SR, Garlet GP et al (2009) CCR5 down-regulates osteoclast function in orthodontic tooth movement. J Dent Res 88: 1037-1041.
    • (2009) J Dent Res , vol.88 , pp. 1037-1041
    • Andrade Jr., I.1    Taddei, S.R.2    Garlet, G.P.3
  • 29
    • 4344634555 scopus 로고    scopus 로고
    • Microrough implant surface topographies increase osteogenesis by reducing osteoclast formation and activity
    • Lossdorfer S, Schwartz Z, Wang L et al (2004) Microrough implant surface topographies increase osteogenesis by reducing osteoclast formation and activity. J Biomed Mater Res A 70: 361-369.
    • (2004) J Biomed Mater Res A , vol.70 , pp. 361-369
    • Lossdorfer, S.1    Schwartz, Z.2    Wang, L.3
  • 30
    • 75649117744 scopus 로고    scopus 로고
    • Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis
    • Kwan Tat S, Amiable N, Pelletier JP et al (2009) Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis. Rheumatology (Oxford) 48: 1482-1490.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 1482-1490
    • Kwan Tat, S.1    Amiable, N.2    Pelletier, J.P.3
  • 31
    • 27144552054 scopus 로고    scopus 로고
    • Comparative study of protein and mRNA expression during osteoclastogenesis
    • Czupalla C, Mansukoski H, Pursche T et al (2005) Comparative study of protein and mRNA expression during osteoclastogenesis. Proteomics 5: 3868-3875.
    • (2005) Proteomics , vol.5 , pp. 3868-3875
    • Czupalla, C.1    Mansukoski, H.2    Pursche, T.3
  • 32
    • 36348953061 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts
    • Li X, Qin L, Bergenstock M et al (2007) Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts. J Biol Chem 282: 33098-33106.
    • (2007) J Biol Chem , vol.282 , pp. 33098-33106
    • Li, X.1    Qin, L.2    Bergenstock, M.3
  • 33
    • 39149096907 scopus 로고    scopus 로고
    • High extracellular inorganic phosphate oncentration inhibits RANK-RANKL signaling in osteoclast-like cells
    • Mozar A, Haren N, Chausseraud M et al (2008) High extracellular inorganic phosphate oncentration inhibits RANK-RANKL signaling in osteoclast-like cells. J Cell Physiol 215: 47-54.
    • (2008) J Cell Physiol , vol.215 , pp. 47-54
    • Mozar, A.1    Haren, N.2    Chausseraud, M.3
  • 34
    • 13044316551 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor family member RANKL mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
    • Hsu H, Lacey D, Dunstan C et al (1999) Tumor necrosis factor receptor family member RANKL mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci USA 96: 3540-3545.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3540-3545
    • Hsu, H.1    Lacey, D.2    Dunstan, C.3
  • 35
    • 85003152202 scopus 로고
    • Modulation of osteoclast differentiation
    • Suda T, Takahashi N, Martin T (1992) Modulation of osteoclast differentiation. Endocr Rev 13: 66-80.
    • (1992) Endocr Rev , vol.13 , pp. 66-80
    • Suda, T.1    Takahashi, N.2    Martin, T.3
  • 36
    • 0023575666 scopus 로고
    • Expression of tartrate-resistant acid phosphatase in bone marrow macrophages
    • Bianco P, Costantini M, Dearden L et al (1987) Expression of tartrate-resistant acid phosphatase in bone marrow macrophages. Basic Appl Histochem 31: 433-440.
    • (1987) Basic Appl Histochem , vol.31 , pp. 433-440
    • Bianco, P.1    Costantini, M.2    Dearden, L.3
  • 37
    • 0037205449 scopus 로고    scopus 로고
    • Parathyroid hormone and parathyroid hormone-related protein exert both pro- and anti-apoptotic effects in mesenchymal cells
    • Chen HL, Demiralp B, Schneider A et al (2002) Parathyroid hormone and parathyroid hormone-related protein exert both pro- and anti-apoptotic effects in mesenchymal cells. J Biol Chem 277: 19374-19381.
    • (2002) J Biol Chem , vol.277 , pp. 19374-19381
    • Chen, H.L.1    Demiralp, B.2    Schneider, A.3
  • 38
    • 33750514356 scopus 로고    scopus 로고
    • Long-term loading inhibits ERK1/2 phosphorylation and increases FGFR3 expression in MC3T3-E1 osteoblast cells
    • Jackson R, Kumarasuriyar A, Nurcombe V et al (2006) Long-term loading inhibits ERK1/2 phosphorylation and increases FGFR3 expression in MC3T3-E1 osteoblast cells. J Cell Physiol 209: 894-904.
    • (2006) J Cell Physiol , vol.209 , pp. 894-904
    • Jackson, R.1    Kumarasuriyar, A.2    Nurcombe, V.3
  • 39
    • 33846855997 scopus 로고    scopus 로고
    • Effects of transient PTH on early proliferation, apoptosis, and subsequent differentiation of osteoblasts in primary osteoblast cultures
    • Wang Y, Liu Y, Rowe D (2007) Effects of transient PTH on early proliferation, apoptosis, and subsequent differentiation of osteoblasts in primary osteoblast cultures. Am J Physiol Endocrinol Metab 292: E594-E603.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Wang, Y.1    Liu, Y.2    Rowe, D.3
  • 40
    • 68249152387 scopus 로고    scopus 로고
    • Dental pulp and periodontal ligament cells support osteoclastic differentiation
    • Uchiyama M, Nakamichi Y, Nakamura M et al (2009) Dental pulp and periodontal ligament cells support osteoclastic differentiation. J Dent Res 88: 609-614.
    • (2009) J Dent Res , vol.88 , pp. 609-614
    • Uchiyama, M.1    Nakamichi, Y.2    Nakamura, M.3
  • 41
    • 0034014375 scopus 로고    scopus 로고
    • In vivo demonstration that human parathyroid hormone 1-38 inhibits the expression of osteoprotegerin in bone with the kinetics of an immediate early gene
    • Onyia JE, Miles RR, Yang X et al (2000) In vivo demonstration that human parathyroid hormone 1-38 inhibits the expression of osteoprotegerin in bone with the kinetics of an immediate early gene. J Bone Miner Res 15: 863-871.
    • (2000) J Bone Miner Res , vol.15 , pp. 863-871
    • Onyia, J.E.1    Miles, R.R.2    Yang, X.3
  • 42
    • 23044434673 scopus 로고    scopus 로고
    • Normal human osteoclasts formed from peripheral blood monocytes express PTH type 1 receptors and are stimulated by PTH in the absence of osteoblasts
    • Dempster D, Hughes-Begos C, Plavetic-Chee K et al (2005) Normal human osteoclasts formed from peripheral blood monocytes express PTH type 1 receptors and are stimulated by PTH in the absence of osteoblasts. J Cell Biochem 95: 139-148.
    • (2005) J Cell Biochem , vol.95 , pp. 139-148
    • Dempster, D.1    Hughes-Begos, C.2    Plavetic-Chee, K.3
  • 43
    • 0029759907 scopus 로고    scopus 로고
    • Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages
    • Isogai Y, Akatsu T, Ishizuya T et al (1996) Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages. J Bone Miner Res 11: 1384-1393.
    • (1996) J Bone Miner Res , vol.11 , pp. 1384-1393
    • Isogai, Y.1    Akatsu, T.2    Ishizuya, T.3
  • 44
    • 0030968591 scopus 로고    scopus 로고
    • Rapid and long-term effects of PTH(1-34) on growth plate chondrocytes are mediated through two different pathways in a cell-maturation-dependent manner
    • Schwartz Z, Semba S, Graves D et al (1997) Rapid and long-term effects of PTH(1-34) on growth plate chondrocytes are mediated through two different pathways in a cell-maturation-dependent manner. Bone 21: 249-259.
    • (1997) Bone , vol.21 , pp. 249-259
    • Schwartz, Z.1    Semba, S.2    Graves, D.3
  • 45
    • 70349577508 scopus 로고    scopus 로고
    • RANKL/RANK as key factors for osteoclast development and bone loss in arthropathies
    • Leibbrandt A, Penninger JM (2009) RANKL/RANK as key factors for osteoclast development and bone loss in arthropathies. Adv Exp Med Biol 649: 100-113.
    • (2009) Adv Exp Med Biol , vol.649 , pp. 100-113
    • Leibbrandt, A.1    Penninger, J.M.2
  • 48
    • 1642463877 scopus 로고    scopus 로고
    • Periodontal ligament cells under intermittent tensile stress regulate mRNA expression of osteoprotegerin and tissue inhibitor of matrix metalloprotease-1 and -2
    • Tsuji K, Uno K, Zhang GX et al (2004) Periodontal ligament cells under intermittent tensile stress regulate mRNA expression of osteoprotegerin and tissue inhibitor of matrix metalloprotease-1 and -2. J Bone Miner Metab 22: 94-103.
    • (2004) J Bone Miner Metab , vol.22 , pp. 94-103
    • Tsuji, K.1    Uno, K.2    Zhang, G.X.3
  • 49
    • 33846200050 scopus 로고    scopus 로고
    • RANKL expression in rat periodontal ligament subjected to a continuous orthodontic force
    • Kim T, Handa A, Iida J et al (2007) RANKL expression in rat periodontal ligament subjected to a continuous orthodontic force. Arch Oral Biol 52: 244-250.
    • (2007) Arch Oral Biol , vol.52 , pp. 244-250
    • Kim, T.1    Handa, A.2    Iida, J.3
  • 50
    • 34247387217 scopus 로고    scopus 로고
    • The new concept of periodontal disease pathogenesis requires new and novel therapeutic strategies
    • Taubman MA, Kawai T, Han X (2007) The new concept of periodontal disease pathogenesis requires new and novel therapeutic strategies. J Clin Periodontol 34: 367-369.
    • (2007) J Clin Periodontol , vol.34 , pp. 367-369
    • Taubman, M.A.1    Kawai, T.2    Han, X.3
  • 51
    • 33746452167 scopus 로고    scopus 로고
    • Parathyroid hormone(1-34) mediates proliferative and apoptotic signaling in human periodontal ligament cells in vitro via protein kinase C-dependent and protein kinase A-dependent pathways
    • Lossdorfer S, Gotz W, Rath-Deschner B et al (2006) Parathyroid hormone(1-34) mediates proliferative and apoptotic signaling in human periodontal ligament cells in vitro via protein kinase C-dependent and protein kinase A-dependent pathways. Cell Tissue Res 325: 469-479.
    • (2006) Cell Tissue Res , vol.325 , pp. 469-479
    • Lossdorfer, S.1    Gotz, W.2    Rath-Deschner, B.3
  • 52
    • 0031113674 scopus 로고    scopus 로고
    • Expression of extracellular matrix proteins in human periodontal ligament cells during mineralization in vitro
    • Nohutcu RM, McCauley LK, Koh AJ et al (1997) Expression of extracellular matrix proteins in human periodontal ligament cells during mineralization in vitro. J Periodontol 68: 320-327.
    • (1997) J Periodontol , vol.68 , pp. 320-327
    • Nohutcu, R.M.1    McCauley, L.K.2    Koh, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.