The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability

Protein and Cell

Volumn 2, Issue 9, 2011, Pages 755-763

  Ito, Kentaro ^a   Takahashi, Akinori ^a   Morita, Masahiro ^a   Suzuki, Toru ^a   Yamamoto, Tadashi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY   (Japan)

Author keywords

apoptosis; CCR4 NOT; deadenylation; P bodies; small interfering RNA

Indexed keywords

CASPASE 4; CCR4 NOT DEADENYLASE COMPLEX; CELL PROTEIN; CNOT1 PROTEIN SUBUNIT; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; MULTIPROTEIN COMPLEX; PROTEIN CNOT6L; PROTEIN SUBUNIT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADENYLATION; APOPTOSIS; ARTICLE; CELL VIABILITY; CELLS AND CELL COMPONENTS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MESSENGER RNA DEADENYLATION; P BODIES; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA DEGRADATION; RNA STABILITY; RNA TRANSLATION;

EID: 80955125826     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-011-1092-4     Document Type: Article

References (29)

1. Bartlam, M., and Yamamoto, T. (2010). The structural basis for deadenylation by the CCR4-NOT complex. Protein Cell 1, 443-452.
2. Behm-Ansmant, I., Rehwinkel, J., Doerks, T., Stark, A., Bork, P., and Izaurralde, E. (2006). mRNA degradation by miRNAs and GW182 requires both CCR4: NOT deadenylase and DCP1: DCP2 decapping complexes. Genes Dev 20, 1885-1898.
3. Berthet, C., Morera, A. M., Asensio, M. J., Chauvin, M. A., Morel, A. P., Dijoud, F., Magaud, J. P., Durand, P., and Rouault, J. P. (2004). CCR4-associated factor CAF1 is an essential factor for spermatogenesis. Mol Cell Biol 24, 5808-5820.
4. Chen, C., Ito, K., Takahashi, A., Suzuki, T., Ge, W., Nakazawa, T., Yamamoto, T., and Yokoyama, K. (2011). Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development. Biophys Biochem Res Commun 411, 360-364.
5. Chicoine, J., Benoit, P., Gamberi, C., Paliouras, M., Simonelig, M., and Lasko, P. (2007). Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression. Dev Cell 13, 691-704.
6. Collart, M. A. (2003). Global control of gene expression in yeast by the Ccr4-Not complex. Gene 313, 1-16.
7. Collart, M. A., and Timmers, H. T. (2004). The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways? Prog Nucleic Acid Res Mol Biol 77, 289-322.
8. Eulalio, A., Behm-Ansmant, I., Schweizer, D., and Izaurralde, E. (2007). P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol Cell Biol 27, 3970-3981.
9. Garneau, N. L., Wilusz, J., and Wilusz, C. J. (2007). The highways and byways of mRNA decay. Nat Rev Mol Cell Biol 8, 113-126.
10. Graces, R., Gillon, W., and Pai, E. F. (2009). Atomic model of human Rcd-1 reveals an armadillo-like-repeat protein with in vitro nucleic acid binding properties. Protein Sci 16, 176-188.
11. Harding, H. P., Novoa, I., Zhang, Y., Zeng, H., Wek, R., Schapira, M., and Ron, D. (2000). Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6, 1099-1108.
12. Hitomi, J., Katayama, T., Taniguchi, M., Honda, A., Imaizumi, K., and Tohyama, M. (2004). Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12. Neurosci Lett 357, 127-130.
13. Ito, K., Inoue, T., Yokoyama, K., Morita, M., Suzuki, T., and Yamamoto, T. (2011). CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death. Genes Cells 16, 368-379.
14. Lin, J. H., Li, H., Yasumura, D., Cohen, H. R., Chao, Z., Panning, B., Shokat, K. M., LaVail, M. M., and Walter, P. (2007). IRE1 signaling affects cell fate during the unfolded protein response. Science 318, 944-949.
15. Maillet, L., Tu, C., Hong, Y. K., Shuster, E. O., and Collart, M. A. (2000). The essential function of Not1 lies within the Ccr4-Not complex. J Mol Biol 303, 131-143.
16. Miyasaka, T., Morita, M., Ito, K., Suzuki, T., Fukuda, H., Takeda, S., Inoue, J., Semba, K., and Yamamoto, T. (2008). Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex. Cancer Sci 99, 755-761.
17. Morita, M., Suzuki, T., Nakamura, T., Yokoyama, K., Miyasaka, T., and Yamamoto, T. (2007). Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. Mol Cell Biol 27, 4980-4990.
18. Nakagawa, T., Zhu, H., Morishima, N., Li, E., Xu, J., Yankner, B. A., and Yuan, J. (2000). Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403, 98-103.
19. Nakamura, T., Yao, R., Ogawa, T., Suzuki, T., Ito, C., Tsunekawa, N., Inoue, K., Ajima, R., Miyasaka, T., Yoshida, Y., et al. (2004). Oligoastheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta. Nat Genet 36, 528-533.
20. Neely, G. G., Kuba, K., Cammarato, A., Isobe, K., Amann, S., Zhang, L., Murata, M., Elmén, L., Gupta, V., Arora, S., et al. (2010). A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell 141, 142-153.
21. Sandler, H., Kreth, J., Timmers, H. T. M., and Stoecklin, G. (2011). Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin. Nucleic Acids Res 39, 4373-4386.
22. Schröder, M., and Kaufman, R. J. (2005). ER stress and the unfolded protein response. Mutat Res 569, 29-63.
23. Sheth, U., and Parker, R. (2003). Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300, 805-808.
24. Temme, C., Zaessinger, S., Meyer, S., Simonelig, M., and Wahle, E. (2004). A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila. EMBO J 23, 2862-2871.
25. Temme, C., Zhang, L., Kremmer, E., Ihling, C., Chartier, A., Sinz, A., Simonelig, M., and Wahle, E. (2010). Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation. RNA 16, 1356-1370.
26. Tucker, M., Staples, R. R., Valencia-Sanchez, M. A., Muhlrad, D., and Parker, R. (2002). Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae. EMBO J 21, 1427-1436.
27. Wang, H., Morita, M., Yang, X., Suzuki, T., Yang, W., Wang, J., Ito, K., Wang, Q., Zhao, C., Bartlam, M., et al. (2010). Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. EMBO J 29, 2566-2576.
28. Winkler, G. S., Mulder, K. W., Bardwell, V. J., Kalkhoven, E., and Timmers, H. T. (2006). Human Ccr4-Not complex is a liganddependent repressor of nuclear receptor-mediated transcription. EMBO J 25, 3089-3099.
29. Zinszner, H., Kuroda, M., Wang, X., Batchvarova, N., Lightfoot, R. T., Remotti, H., Stevens, J. L., and Ron, D. (1998). CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 12, 982-995.