Camps Quinolinol Synthesis

Name Reactions in Heterocyclic Chemistry

Volumn , Issue , 2005, Pages 386-389

  Pflum, Derek A ^a  

^a PFIZER INC   (United States)

Author keywords

Camps; Droebner; Gould Jacobs; Isoquinolines; Pictet Hubert; Pomeranz Fritsch; Quinolines; Riehm

Indexed keywords

CAMPS; DROEBNER; GOULD-JACOBS; ISOQUINOLINES; PICTET-HUBERT; POMERANZ-FRITSCH; QUINOLINES; RIEHM;

EID: 80955125113     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/0471704156.ch9     Document Type: Chapter

References (10)

1. For consistency, the products are drawn as the quinolin-2-ol1 or quinolin-4-ol, regardless of how they were drawn in the primary literature.
2. Camps, R. Chem. Ber. 1899, 32, 3228.
3. Camps, R. Arch. Pharm. 1899, 237, 659.
4. β-Diketone i could be an intermediate in the pathway leading to 2. No investigations into the intermediacy of this type of compound have been performed.
5. Clemence, F.; LeMartret, O.; Collard, J. J. Heterocyclic Chem. 1984, 21, 1345.
6. Elderfield, R. C; Todd, W. H.; Gerber, S. "Heterocyclic Compounds" Vol. 6, R. C. Elderfield, ed. J. Wiley and Sons, New York, 1957, 576.
7. Hino, K.; Kawashima, K.; Oka, M.; Nagai, Y.; Uno, H.; Matsui, J. Chem. Pharm. Bull. 1989, 37, 110.
8. The authors also investigated R=3-CF3 and 4-CF3, but the yields were reported based upon the Grignard reagent (13% and 18% respectively) and are therefore excluded.
9. Witkop, B.; Patrick, J. B.; and Rosenblum, M. J. Am. Chem. Soc. 1951, 73, 2641.
10. Barret, R.; Ortillon, S.; Mulamba, M.; Laronze, J. Y.; Trentesaux, C; Levy, J. J. Heterocyclic Chem. 2000, 37, 241.