Prophylactic cranial irradiation in non-small cell lung cancer patients: Who might be the candidates?

Cancer Management and Research

Volumn 3, Issue 1, 2011, Pages 287-294

  Dimitropoulos, Charalampos ^a   Hillas, Georgios ^a   Nikolakopoulou, Sofia ^a   Kostara, Ioanna ^a   Sagris, Konstantinos ^a   Vlastos, Fotis ^a   Alchanatis, Manos ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Brain metastases; Clinical and epidemiological factors; NSCLC; PCI

Indexed keywords

ADRENAL METASTASIS; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BONE METASTASIS; BRAIN METASTASIS; CANCER RADIOTHERAPY; CANCER RISK; CANCER STAGING; COMORBIDITY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HYPERTENSION; LUNG METASTASIS; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; OVERALL SURVIVAL; SEX DIFFERENCE; SMOKING; TUMOR CLASSIFICATION; TUMOR VOLUME;

EID: 80955124121     PISSN: None     EISSN: 11791322     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, Boyle P. Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol. 2007;18:581-592.
2. Walker S. Updates in non-small cell lung cancer. Clin J Oncol Nurs. 2008;2:587-596.
3. Albain KS, Rusch VW, Crowley JJ, et al. Concurrent cisplatin/etoposide plus chest radiotherapy followed by surgery for stages IIIA (N2) and IIIB non-small-cell lung cancer: Mature results of Southwest Oncology Group Phase II study 8805. J Clin Oncol. 1995;13:1880-1892.
4. Andre F, Grunenwald D, Pujol JL, et al. Patterns of relapse of N2 nonsmall-cell lung carcinoma patients treated with preoperative chemotherapy: Should prophylactic cranial irradiation be reconsidered? Cancer. 2001;91:2394-2400.
5. Cox JD, Scott CB, Byhardt RW, et al. Addition of chemotherapy to radiation therapy alters failure patterns by cell type within non-small cell carcinoma of lung (NSCCL): Analysis of Radiation Therapy Oncology Group (RTOG) trials. Int J Radiat Oncol Biol Phys. 1999;43:505-509.
6. Cooper JD, Silverman S, Clement JA. Prophylactic cranial irradiation for lung cancer patients at high risk for development of cerebral metastasis: Results of a prospective randomized trial conducted by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys. 1991;21:637-643.
7. Stuschke M, Eberhardt W, Pottgen C, et al. Prophylactic cranial irradiation in locally advanced nonsmall-cell lung cancer after multimodality treatment: Long-term follow-up and investigations of late neuropsychologic effects. J Clin Oncol. 1999;17:2700-2709.
8. Andre F, Grunenwald D, Pujol JL, et al. Patterns of relapse of N2 nonsmall-cell lung carcinoma patients treated with preoperative chemotherapy: Should prophylactic cranial irradiation be reconsidered? Cancer. 2001;91:2394-2400.
9. Strauss GM, Herndon JE, Sherman DD, et al. Neoadjuvant chemotherapy and radiotherapy followed by surgery in stage IIIA non-small cell carcinoma of the lung: Report of a Cancer and Leukemia Group B phase II study. J Clin Oncol. 1992;10:237-1244.
10. Rusch VW, Griffin BR, Livingston RB. The role of prophylactic cranial irradiation in regionally advanced non-small cell lung cancer. A Southwest Oncology Group Study. J Thorac Cardiovasc Surg. 1989;98:535-539.
11. Skarin A, Jochelson M, Sheldon T, et al. Neoadjuvant chemotherapy in marginally resectable stage III M0 non-small cell lung cancer: Longterm follow-up in 41 patients. J Surg Oncol. 1989;40:266-274.
12. Russell AH, Pajak TE, Selim HM, et al. Prophylactic cranial irradiation for lung cancer patients at high risk for development of cerebral metastasis: Results of a prospective randomized trial conducted by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys. 1991;21:637-643.
13. Umsawasdi T, Valdivieso M, Chen TT, et al. Role of elective brain irradiation during combined chemoradiotherapy for limited disease non-small cell lung cancer. J Neuro Oncol. 1984;2:253-259.
14. Cox JD, Stanley K, Petrovich Z, Paig C, Yesner R. Cranial irradiation in cancer of the lung of all cell types. JAMA. 1981;245:469-472.
15. Pöttgen C, Eberhardt W, Grannass A, et al. Prophylactic cranial irradiation in operable stage IIIA non-small-cell lung cancer treated with neoadjuvant chemoradiotherapy: Results from a German multicenter trial. J Clin Oncol. 2007;25:4987-4992.
16. Yavuz AA, Topkan E, Onal C, Yavuz MN. Prophylactic cranial irradiation in locally advanced non-small cell lung cancer: Outcome of recursive partitioning analysis group I patients. J Exp Clin Cancer Res. 2008;27:80.
17. Robnett TJ, Machtay M, Stevenson JP, Algazy KM, Hahn SM. Factors affecting the risk of brain metastases after definitive chemoradiation for locally advanced non-small-cell lung carcinoma. J Clin Oncol. 2001;19:1344-1349.
18. Law A, Karp DD, Dipetrillo T, Daly BT. Emergence of increased cerebral metastasis after high-dose preoperative radiotherapy with chemotherapy in patients with locally advanced non-small cell lung carcinoma. Cancer. 2001;92:160-164.
19. Ceresoli GL, Reni M, Chiesa G, et al. Brain metastases in locally advanced nonsmall cell lung carcinoma after multimodality treatment: Risk factors analysis. Cancer. 2002;95:605-612.
20. Carolan H, Sun AY, Bezjak A, et al. Does the incidence and outcome of brain metastases in locally advanced non-small cell lung cancer justify prophylactic cranial irradiation or early detection? Lung Cancer. 2005;49:109-115.
21. Sobin LH, Wittekind C; and the International Union Against Cancer (UICC), editors. TNM Classification of Malignant Tumors. 6th ed. New York, NY: Wiley-Liss; 2002:99-103.
22. Alberts M. Lung Cancer Guidelines. Chest. 2003;123:1-2.
23. Alberts M. Diagnosis and management of lung cancer. Executive summary. Chest. 2007;132:1-19.
24. Addeo R, Caraglia M, Faiola V, et al. Concomitant treatment of brain metastasis with whole brain radiotherapy [WBRT] and temozolomide [TMZ] is active and improves quality of life. BMC. 2007;7:18.
25. Ma S, Xu Y, Deng Q, Yu X. Treatment of brain metastasis from nonsmall cell lung cancer with whole brain radiotherapy and Gefitinib in a Chinese population. Lung Cancer. 2009;65:198-203.
26. Jacot W, Quantin X, Boher JM, et al. Brain metastases at the time of presentation of non-small cell lung cancer: A multi-centric AERIO analysis of prognostic factors. Br J Cancer. 2001;84:903-909.
27. Penel N, Brichet A, Prevost B, et al. Prognostic factors for synchronous brain metastases from lung cancer. Lung Cancer. 2001;33:143-154.
28. Arrieta O, Saavedra-Perez D, Kuri R, et al. Brain metastasis development and poor survival associated with carcinoembryonic antigen (CEA) level in advanced non-small cell cancer: A prospective analysis. BMC Cancer. 2009;9:119.
29. Robnett T, Machtay M, Stevenson J, et al. Factors affecting the risk of brain metastases after definitive chemoradiation for locally advanced non-small-cell lung carcinoma. J Clin Oncol. 2001;19:1344-1349.
30. Bajard A, Westeel V, Dubiez A. Multivariate analysis of factors predictive of brain metastases in localized non-small cell lung carcinoma. Lung Cancer. 2004;45:317-323.
31. Mujoomdar A, Austin J, Malhota R, et al. Clinical predictors of metastatic disease to the brain from non-small cell lung carcinoma: Primary tumor size, cell type, and lymph node metastases. Radiology. 2007;242:882-888.
32. Shi A, Digumarthy S, Temel J, Halpern EF, Kuester LB, Aquino SL. Does initial staging or tumor histology better identify asymptomatic brain metastases in patients with non-small cell lung caner? J Thorac Oncol. 2006;1:205-210.
33. Ceresoli GL, Reni M, Chiesa G, et al. Brain metastases in locally advanced non-small cell lung carcinoma after multimodality treatment: Risk factors analysis. Cancer. 2002;95:605-612.
34. Schouten LJ, Rutten J, Huveneers HA, Twinjstra A. Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer. 2002;94:2698-2705.
35. Gore E. Brain metastases in very young patients with lung cancer are still brain metastases. Onkologie. 2008;31:297-268.
36. Jacobs RH, Awan A, Bitran JD, et al. Prophylactic cranial irradiation in adenocarcinoma of the lung: A possible role. Cancer. 1987;59: 2016-2019.
37. Tang SG, Lin FJ, Leung VM. Impact of cranial irradiation in adenocarcinoma of the lung. J Formos Med Assoc. 1993;92:413-419.