Model organisms reveal insight into human neurodegenerative disease: Ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS

Journal of Molecular Neuroscience

Volumn 45, Issue 3, 2011, Pages 676-683

  Bonini, Nancy M ^a   Gitler, Aaron D ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

ALS; Ataxin 2; Drosophila; Polyglutamine disease; Repeat expansions; TDP 43; Yeast

Indexed keywords

POLYGLUTAMINE; TAR DNA BINDING PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; BIOLOGICAL MODEL; CAG REPEAT; CONFERENCE PAPER; DROSOPHILA MELANOGASTER; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; NONHUMAN; SACCHAROMYCES CEREVISIAE; SPINOCEREBELLAR ATAXIA TYPE 2; SPINOCEREBELLAR DEGENERATION; TDP 43 PROTEINOPATHY;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; HUMANS; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; PEPTIDES; RISK FACTORS; TRINUCLEOTIDE REPEAT EXPANSION; YEASTS;

DROSOPHILA MELANOGASTER;

EID: 80855131505     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-011-9548-9     Document Type: Conference Paper

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