The effect of calcium hydroxide on the steroid component of Ledermix ® and Odontopaste ®

International Endodontic Journal

Volumn 44, Issue 12, 2011, Pages 1162-1169

  Athanassiadis, M ^a   Jacobsen, N ^a   Parashos, P ^b  

^a Australian Dental Manufacturing   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Calcium hydroxide; Ledermix paste; Odontopaste; Triamcinolone acetonide

Indexed keywords

ALKALI; ANTIINFECTIVE AGENT; BIOMEDICAL AND DENTAL MATERIALS; CALCIUM HYDROXIDE; CLINDAMYCIN; DEMECLOCYCLINE; LEDERMIX; TRIAMCINOLONE ACETONIDE;

ARTICLE; CHEMISTRY; DRUG COMBINATION; DRUG INTERACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MATERIALS TESTING; PH; POWDER; TIME;

ALKALIES; ANTI-BACTERIAL AGENTS; CALCIUM HYDROXIDE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLINDAMYCIN; DEMECLOCYCLINE; DRUG COMBINATIONS; DRUG INTERACTIONS; HUMANS; HYDROGEN-ION CONCENTRATION; MATERIALS TESTING; POWDERS; ROOT CANAL IRRIGANTS; TIME FACTORS; TRIAMCINOLONE ACETONIDE;

EID: 80855130683     PISSN: 01432885     EISSN: 13652591     Source Type: Journal    
DOI: 10.1111/j.1365-2591.2011.01940.x     Document Type: Article

References (23)

1. Abbott PV, Hume WR, Heithersay GS (1989) Effects of combining Ledermix and calcium hydroxide pastes on the diffusion of corticosteroid and tetracycline through human tooth roots in vitro. Endodontics & Dental Traumatology 5, 188-92.
2. Adamidou V (2010) In vitro investigation of teeth discolouration with different endodontic medicaments (MDentSci Thesis). Leeds, UK: University of Leeds.
3. AOAC (2009) Single laboratory validation acceptance criteria (chemistry methods), Association of Analytical Communities. (accessed 19 April 2011).
4. APVMA (2004) Guidelines for the validation of analytical methods for active constituent, agricultural and veterinary chemical products, Australian Pesticides and Veterinary Medicines Authority. (accessed 19 April 2011).
5. Armstrong TI (2009) Calcium hydroxide. In: Rowe R, Sheskey PJ, Quinn ME, eds. Handbook of pharmaceutical excipients, 6th edn. London, UK: Pharmaceutical Press, p. 91.
6. Chen H, Teixeira FB, Ritter AL, Levin L, Trope M (2008) The effect of intracanal anti-inflammatory medicaments on external root resorption of replanted dog teeth after extended extra-oral dry time. Dental Traumatology 24, 74-8.
7. Conrow RE, Dillow GW, Bian L et al. (2002) Corticosteroid decomposition via a mixed anhydride. Journal of Organic Chemistry 67, 6835-6.
8. Day PF, Duggal DS, High AS et al. (2011) Discoloration of teeth following avulsion and replantation; results from a multi-center randomized controlled trial. Journal of Endodontics 37, in press.
9. Dekker D, Buijs DJ (1980) Stability of corticosteroids under anaerobic conditions. C6 and C9 fluorine-containing corticosteroids. International Journal of Pharmaceutics 5, 195-206.
10. Ehrmann EH (1981) Pulpotomies in traumatized and carious permanent teeth using a corticosteroid-antibiotic preparation. International Endodontic Journal 14, 149-56.
11. European Medicines Agency (2006) International Conference on Harmonization (ICH) Topic Q2 (R1) validation of analytical procedures: text and methodology. (accessed 19 April 2011).
12. Görög S (2010) Analytical aspects of drug stability studies. In: Makin HLJ, Gower DB, eds. Steroid analysis, 2nd edn. London, UK: Springer, pp. 1134-5.
13. Hansen J, Bundgaard H (1980) Studies on the stability of corticosteroids V. The degradation pattern of hydrocortisone in aqueous solution. International Journal of Pharmaceutics 6, 307-19.
14. Heithersay GS (1975) Calcium hydroxide in the treatment of pulpless teeth with associated pathology. Journal of the British Endodontic Society 8, 74-93.
15. Kim ST, Abbott PV, McGinley P (2000) The effects of Ledermix paste on discolouration of mature teeth. International Endodontic Journal 33, 227-32.
16. NATA (2009) Technical note 17-April 2009: guidelines for the validation and verification of chemical test methods. (accessed 19 April 2011).
17. Nygaard L, Drohse Kilde H, Andersen SG, Henriksen L, Overby V (2004) Development and validation of a reversed-phase liquid chromatographic method for analysis of degradation products of estradiol in Vagifem tablets. Journal of Pharmaceutical and Biomedical Analysis 34, 265-76.
18. Ogata M, Noro Y, Yamada M, Tahara T, Nishimura T (1998) Photodegradation products of methylprednisolone suleptanate in aqueous solution - evidence of a bicyclo[3.1.0]hex-3-en-2-one intermediate. Journal of Pharmaceutical Sciences 87, 91-5.
19. Plutzer B (2009) Comparative efficacy of endodontic medicaments against Enterococcus faecalis biofilms. DCD thesis. Adelaide, Australia: University of Adelaide.
20. Spangler M, Mularz E (2001) A validated, stability-indicating method for the assay of dexamethasone in drug substance and drug product analyses, and the assay of preservatives in drug product. Chromatographia 54, 329-34.
21. Taylor MA, Humen WR, Heithersay GS (1989) Some effects of Ledermix paste and Pulpdent paste on mouse fibroblasts and on bacteria in vitro. Endodontics & Dental Traumatology 5, 266-73.
22. Teng XW, Cutler DC, Davies NM (2003) Degradation kinetics of mometasone furoate in aqueous systems. International Journal of Pharmaceutics 259, 129-41.
23. Tronstad L, Andreasen JO, Hasselgren G, Kristerson L, Riis I (1981) pH changes in dental tissues after root canal filling with calcium hydroxide. Journal of Endodontics 7, 17-21.