-
1
-
-
0141566431
-
Prevalence and burden of overactive bladder in the United States
-
DOI 10.1007/s00345-002-0301-4
-
WF Stewart JB Van Rooyen GW Cundiff P Abrams AR Herzog R Corey TL Hunt AJ Wein 2003 Prevalence and burden of overactive bladder in the United States World J Urol 20 6 327 36 12811491 1:STN:280:DC%2BD3s3osVWkuw%3D%3D (Pubitemid 44175300)
-
(2003)
World Journal of Urology
, vol.20
, Issue.6
, pp. 327-336
-
-
Stewart, W.F.1
Van Rooyen, J.B.2
Cundiff, G.W.3
Abrams, P.4
Herzog, A.R.5
Corey, R.6
Hunt, T.L.7
Wein, A.J.8
-
2
-
-
11144267173
-
Defining overactive bladder: Epidemiology and burden of disease
-
DOI 10.1016/j.urology.2004.10.047, PII S0090429504012440
-
A Tubaro 2004 Defining overactive bladder: epidemiology and burden of disease Urology 64 6 Suppl 1 2 6 15621220 10.1016/j.urology.2004.10.047 (Pubitemid 40038567)
-
(2004)
Urology
, vol.64
, Issue.6 SUPPL. 1
, pp. 2-6
-
-
Tubaro, A.1
-
3
-
-
0036774192
-
Differential gene expression of cholinergic muscarinic receptor subtypes in male and female normal human urinary bladder
-
DOI 10.1016/S0090-4295(02)01819-8, PII S0090429502018198
-
S Sigala G Mirabella A Peroni G Pezzotti C Simeone P Spano SC Cunico 2002 Differential gene expression of cholinergic muscarinic receptor subtypes in male and female normal human urinary bladder Urology 60 4 719 25 12385950 10.1016/S0090-4295(02)01819-8 (Pubitemid 35246475)
-
(2002)
Urology
, vol.60
, Issue.4
, pp. 719-725
-
-
Sigala, S.1
Mirabella, G.2
Peroni, A.3
Pezzotti, G.4
Simeone, C.5
Spano, P.6
Cunico, S.C.7
-
4
-
-
0037247736
-
Antimuscarinics and the overactive detrusor - Which is the main mechanism of action?
-
DOI 10.1016/S0302-2838(02)00540-7, PII S0302283802005407
-
KE Andersson M Yoshida 2003 Antimuscarinics and the overactive detrusor-which is the main mechanism of action? Eur Urol 43 1 1 5 12507537 10.1016/S0302-2838(02)00540-7 1:CAS:528:DC%2BD3sXlvFWktrw%3D (Pubitemid 36134308)
-
(2003)
European Urology
, vol.43
, Issue.1
, pp. 1-5
-
-
Andersson, K.-E.1
Yoshida, M.2
-
5
-
-
67649400846
-
Antimuscarinic drugs for the treatment of overactive bladder: Are they really all the same?-A comparative review of data pertaining to pharmacological and physiological aspects
-
This is an excellent review of the mechanisms of action of antimuscarinics at the muscarinic receptors and adverse CNS effects
-
A Wiedemann PA Schwantes 2007 Antimuscarinic drugs for the treatment of overactive bladder: are they really all the same?-A comparative review of data pertaining to pharmacological and physiological aspects Euro J Ger 9 suppl 1 29 42 This is an excellent review of the mechanisms of action of antimuscarinics at the muscarinic receptors and adverse CNS effects
-
(2007)
Euro J Ger
, vol.9
, Issue.SUPPL. 1
, pp. 29-42
-
-
Wiedemann, A.1
Schwantes, P.A.2
-
6
-
-
14844320094
-
Antimuscarinic agents: Implications and concerns in the management of overactive bladder in the elderly
-
DOI 10.1016/S0149-2918(05)80030-X
-
GG Kay LJ Granville 2005 Antimuscarinic agents: implications and concerns in the management of overactive bladder in the elderly Clin Ther 27 1 127 38 15763613 10.1016/j.clinthera.2005.01.006 1:CAS:528:DC%2BD2MXis1Wltb0%3D quiz 139-140 (Pubitemid 40342583)
-
(2005)
Clinical Therapeutics
, vol.27
, Issue.1
, pp. 127-138
-
-
Kay, G.G.1
Granville, L.J.2
-
7
-
-
0027636902
-
The problems of anticholinergic adverse effects in older patients
-
8369593 10.2165/00002512-199303040-00004 1:STN:280:DyaK3sznvFertQ%3D%3D
-
M Feinberg 1993 The problems of anticholinergic adverse effects in older patients Drugs Aging 3 4 335 48 8369593 10.2165/00002512-199303040-00004 1:STN:280:DyaK3sznvFertQ%3D%3D
-
(1993)
Drugs Aging
, vol.3
, Issue.4
, pp. 335-48
-
-
Feinberg, M.1
-
8
-
-
0347319044
-
Age-related changes in pharmacokinetics and pharmacodynamics: Basic principles and practical applications
-
DOI 10.1046/j.1365-2125.2003.02007.x
-
AA Mangoni SH Jackson 2004 Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications Br J Clin Pharmacol 57 1 6 14 14678335 10.1046/j.1365-2125.2003.02007.x 1:CAS:528:DC%2BD2cXotlOjtA%3D%3D (Pubitemid 38067945)
-
(2004)
British Journal of Clinical Pharmacology
, vol.57
, Issue.1
, pp. 6-14
-
-
Mangoni, A.A.1
Jackson, S.H.D.2
-
9
-
-
35148841097
-
Muscarinic receptor antagonists for overactive bladder
-
17922784 10.1111/j.1464-410X.2007.07205.x 1:CAS:528:DC%2BD2sXhtlGgur7M This is a full review of antimuscarinic drugs with respect to efficacy, tolerability and safety
-
P Abrams KE Andersson 2007 Muscarinic receptor antagonists for overactive bladder BJU Int 100 5 987 1006 17922784 10.1111/j.1464-410X.2007.07205.x 1:CAS:528:DC%2BD2sXhtlGgur7M This is a full review of antimuscarinic drugs with respect to efficacy, tolerability and safety
-
(2007)
BJU Int
, vol.100
, Issue.5
, pp. 987-1006
-
-
Abrams, P.1
Andersson, K.E.2
-
11
-
-
77954649145
-
Review of cognitive impairment with antimuscarinic agents in elderly patients with overactive bladder
-
20529135 10.1111/j.1742-1241.2010.02449.x 1:STN:280: DC%2BC3cnps1elug%3D%3D This is a review of cognitive side effects of the available antimuscarinics in elderly people
-
A Wagg C Verdejo U Molander 2010 Review of cognitive impairment with antimuscarinic agents in elderly patients with overactive bladder Int J Clin Pract 64 9 1279 86 20529135 10.1111/j.1742-1241.2010.02449.x 1:STN:280:DC%2BC3cnps1elug%3D%3D This is a review of cognitive side effects of the available antimuscarinics in elderly people
-
(2010)
Int J Clin Pract
, vol.64
, Issue.9
, pp. 1279-86
-
-
Wagg, A.1
Verdejo, C.2
Molander, U.3
-
12
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
DOI 10.1038/nrn1824
-
NJ Abbott L Ronnback E Hansson 2006 Astrocyte-endothelial interactions at the blood-brain barrier Nat Rev Neurosci 7 1 41 53 16371949 10.1038/nrn1824 1:CAS:528:DC%2BD2MXhtlaktbjP (Pubitemid 41828930)
-
(2006)
Nature Reviews Neuroscience
, vol.7
, Issue.1
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
13
-
-
54049098327
-
Preserving cognitive function for patients with overactive bladder: Evidence for a differential effect with darifenacin
-
18699842 10.1111/j.1742-1241.2008.01849.x 1:STN:280: DC%2BD1M%2FntVCgtA%3D%3D The authors explain pathophysiologic mechanisms of cognitive side effects of antimuscarinics and review available literature for each drug in clinical and animal studies
-
GG Kay U Ebinger 2008 Preserving cognitive function for patients with overactive bladder: evidence for a differential effect with darifenacin Int J Clin Pract 62 11 1792 800 18699842 10.1111/j.1742-1241.2008.01849.x 1:STN:280:DC%2BD1M%2FntVCgtA%3D%3D The authors explain pathophysiologic mechanisms of cognitive side effects of antimuscarinics and review available literature for each drug in clinical and animal studies
-
(2008)
Int J Clin Pract
, vol.62
, Issue.11
, pp. 1792-800
-
-
Kay, G.G.1
Ebinger, U.2
-
14
-
-
80755189705
-
Anticholinergics for overactive bladder therapy: Central nervous system effects
-
This article explains pathophysiologic mechanisms of cognitive side effects of antimuscarinics and reviews the data from various clinical studies on CNS effects of antimuscarinics
-
M Chancellor T Boone 2011 Anticholinergics for overactive bladder therapy: central nervous system effects CNS Neurosci Ther 00 1 8 This article explains pathophysiologic mechanisms of cognitive side effects of antimuscarinics and reviews the data from various clinical studies on CNS effects of antimuscarinics
-
(2011)
CNS Neurosci Ther
, vol.0
, pp. 1-8
-
-
Chancellor, M.1
Boone, T.2
-
15
-
-
79960173506
-
A comprehensive nonclinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder
-
Accepted Article
-
Callegari E, Malhotra B, Bungay PJ, Webster R, Fenner KS, Kempshall S, Laperle JL, Michel MC, Kay GG. A comprehensive nonclinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder. Br J Clin Pharmacol. 2011: Accepted Article
-
(2011)
Br J Clin Pharmacol
-
-
Callegari, E.1
Malhotra, B.2
Bungay, P.J.3
Webster, R.4
Fenner, K.S.5
Kempshall, S.6
Laperle, J.L.7
Michel, M.C.8
Kay, G.G.9
-
16
-
-
67649414315
-
The role of p-glycoprotein in limiting brain penetration of the peripherally acting anticholinergic overactive bladder drug trospium chloride
-
19389858 10.1124/dmd.109.027144 1:CAS:528:DC%2BD1MXosFenu7s%3D
-
J Geyer O Gavrilova E Petzinger 2009 The role of p-glycoprotein in limiting brain penetration of the peripherally acting anticholinergic overactive bladder drug trospium chloride Drug Metab Dispos 37 7 1371 4 19389858 10.1124/dmd.109.027144 1:CAS:528:DC%2BD1MXosFenu7s%3D
-
(2009)
Drug Metab Dispos
, vol.37
, Issue.7
, pp. 1371-4
-
-
Geyer, J.1
Gavrilova, O.2
Petzinger, E.3
-
17
-
-
0031783832
-
In vivo age-related changes in hepatic drug-oxidizing capacity in humans
-
DOI 10.1046/j.1365-2710.1998.00164.x
-
E Tanaka 1998 In vivo age-related changes in hepatic drug-oxidizing capacity in humans J Clin Pharm Ther 23 4 247 55 9867310 10.1046/j.1365-2710. 1998.00164.x 1:CAS:528:DyaK1MXhsVyjsg%3D%3D (Pubitemid 28532449)
-
(1998)
Journal of Clinical Pharmacy and Therapeutics
, vol.23
, Issue.4
, pp. 247-255
-
-
Tanaka, E.1
-
18
-
-
33644776510
-
Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: Longitudinal cohort study
-
DOI 10.1136/bmj.38740.439664.DE
-
ML Ancelin S Artero F Portet AM Dupuy J Touchon K Ritchie 2006 Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study BMJ 332 7539 455 9 16452102 10.1136/bmj.38740.439664.DE (Pubitemid 43342043)
-
(2006)
British Medical Journal
, vol.332
, Issue.7539
, pp. 455-458
-
-
Ancelin, M.L.1
Artero, S.2
Portet, F.3
Dupuy, A.-M.4
Touchon, J.5
Ritchie, K.6
-
19
-
-
0020674756
-
The risk of anticholinergic toxicity in the elderly: A study of prescribing practices in two populations
-
DG Blazer 2nd CF Federspiel WA Ray W Schaffner 1983 The risk of anticholinergic toxicity in the elderly: a study of prescribing practices in two populations J Gerontol 38 1 31 5 6129272 (Pubitemid 13217827)
-
(1983)
Journals of Gerontology
, vol.38
, Issue.1
, pp. 31-35
-
-
Blazer II, D.G.1
Federspiel, C.F.2
Ray, W.A.3
Schaffner, W.4
-
20
-
-
0033803794
-
Anticholinergic side-effects of drugs in elderly people
-
11089480 1:CAS:528:DC%2BD3cXntFOjtLY%3D
-
J Mintzer A Burns 2000 Anticholinergic side-effects of drugs in elderly people J R Soc Med 93 9 457 62 11089480 1:CAS:528:DC%2BD3cXntFOjtLY%3D
-
(2000)
J R Soc Med
, vol.93
, Issue.9
, pp. 457-62
-
-
Mintzer, J.1
Burns, A.2
-
21
-
-
79952034846
-
Adverse event assessment of antimuscarinics for treating overactive bladder: A network meta-analytic approach
-
21373193 10.1371/journal.pone.0016718 1:CAS:528:DC%2BC3MXivVymtLY%3D This is a current meta-analysis of clinical studies specifically focusing on adverse side effects of the available antimuscarinics, showing similar profiles for all except oral oxybutynin at a greater than 10 mg/d dose
-
TM Kessler LM Bachmann C Minder D Lohrer M Umbehr HJ Schunemann AG Kessels 2011 Adverse event assessment of antimuscarinics for treating overactive bladder: a network meta-analytic approach PLoS ONE 6 2 e16718 21373193 10.1371/journal.pone.0016718 1:CAS:528:DC%2BC3MXivVymtLY%3D This is a current meta-analysis of clinical studies specifically focusing on adverse side effects of the available antimuscarinics, showing similar profiles for all except oral oxybutynin at a greater than 10 mg/d dose
-
(2011)
PLoS ONE
, vol.6
, Issue.2
, pp. 16718
-
-
Kessler, T.M.1
Bachmann, L.M.2
Minder, C.3
Lohrer, D.4
Umbehr, M.5
Schunemann, H.J.6
Kessels, A.G.7
-
22
-
-
33745861002
-
Differential Effects of the Antimuscarinic Agents Darifenacin and Oxybutynin ER on Memory in Older Subjects
-
DOI 10.1016/j.eururo.2006.03.057, PII S0302283806003587
-
G Kay T Crook L Rekeda R Lima U Ebinger M Arguinzoniz M Steel 2006 Differential effects of the antimuscarinic agents darifenacin and oxybutynin ER on memory in older subjects Eur Urol 50 2 317 26 16687205 10.1016/j.eururo.2006. 03.057 1:CAS:528:DC%2BD28XovFWlsLw%3D (Pubitemid 44038078)
-
(2006)
European Urology
, vol.50
, Issue.2
, pp. 317-326
-
-
Kay, G.1
Crook, T.2
Rekeda, L.3
Lima, R.4
Ebinger, U.5
Arguinzoniz, M.6
Steel, M.7
-
24
-
-
33748779090
-
Psychotic disorder induced by oxybutynin presentation of two cases
-
DOI 10.2165/00044011-200626100-00007
-
M Gulsun M Pinar U Sabanci 2006 Psychotic disorder induced by oxybutynin: presentation of two cases Clin Drug Investig 26 10 603 6 17163294 10.2165/00044011-200626100-00007 1:CAS:528:DC%2BD28Xht1Wjs7bL (Pubitemid 44411336)
-
(2006)
Clinical Drug Investigation
, vol.26
, Issue.10
, pp. 603-606
-
-
Gulsun, M.1
Pinar, M.2
Sabanci, U.3
-
25
-
-
0028138698
-
Influences of trospium chloride and oxybutynin on quantitative EEG in healthy volunteers
-
A Pietzko W Dimpfel U Schwantes P Topfmeier 1994 Influences of trospium chloride and oxybutynin on quantitative EEG in healthy volunteers Eur J Clin Pharmacol 47 4 337 43 7875185 10.1007/BF00191165 1:CAS:528:DyaK2MXjvFSrsL0%3D (Pubitemid 24363337)
-
(1994)
European Journal of Clinical Pharmacology
, vol.47
, Issue.4
, pp. 337-343
-
-
Pietzko, A.1
Dimpfel, W.2
Schwantes, U.3
Topfmeier, P.4
-
26
-
-
0035010117
-
Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous system
-
DOI 10.1177/00912700122010528
-
A Todorova B Vonderheid-Guth W Dimpfel 2001 Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous system J Clin Pharmacol 41 6 636 44 11402632 10.1177/00912700122010528 1:CAS:528:DC%2BD3MXks1Kgsrc%3D (Pubitemid 32493358)
-
(2001)
Journal of Clinical Pharmacology
, vol.41
, Issue.6
, pp. 636-644
-
-
Todorova, A.1
Vonderheid-Guth, B.2
Dimpfel, W.3
-
27
-
-
14144252093
-
Effects on sleep of anticholinergics used for overactive bladder treatment in healthy volunteers aged ≥50 years
-
DOI 10.1111/j.1464-410X.2005.05296.x
-
K Diefenbach G Arold A Wollny U Schwantes J Haselmann I Roots 2005 Effects on sleep of anticholinergics used for overactive bladder treatment in healthy volunteers aged > or = 50 years BJU Int 95 3 346 9 15679791 10.1111/j.1464-410X.2005.05296.x 1:CAS:528:DC%2BD2MXit1GrsL4%3D (Pubitemid 40283121)
-
(2005)
BJU International
, vol.95
, Issue.3
, pp. 346-349
-
-
Diefenbach, K.1
Arold, G.2
Wollny, A.3
Schwantes, U.4
Haselmann, J.5
Roots, I.6
-
28
-
-
32444441009
-
Using anticholinergics to treat overactive bladder: The issue of treatment tolerability
-
DOI 10.1016/j.amjmed.2005.12.011, PII S0002934305011915
-
DR Staskin SA MacDiarmid 2006 Using anticholinergics to treat overactive bladder: the issue of treatment tolerability Am J Med 119 3 Suppl 1 9 15 16483863 10.1016/j.amjmed.2005.12.011 (Pubitemid 43227968)
-
(2006)
American Journal of Medicine
, vol.119
, Issue.3 SUPPL. 1
-
-
Staskin, D.R.1
MacDiarmid, S.A.2
-
29
-
-
76049119098
-
Are the effects of oxybutynin on cognition dependent upon the route of administration - Topical or oral? A double-blind placebo controlled study employing sensitive cognitive and psychomotor testing
-
GSD Kay S MacDiarmid M McIIwain N Dahl 2009 Are the effects of oxybutynin on cognition dependent upon the route of administration - topical or oral? A double-blind placebo controlled study employing sensitive cognitive and psychomotor testing Neurourol Urodyn 28 711 2
-
(2009)
Neurourol Urodyn
, vol.28
, pp. 711-2
-
-
Kay, G.S.D.1
MacDiarmid, S.2
McIiwain, M.3
Dahl, N.4
-
30
-
-
34247194557
-
Differential effects of the antimuscarinic agents tolterodine tartrate ER and oxybutynin chloride ER on recent memory in older subjects
-
G Kay K Kardiasmenos T Crook 2006 Differential effects of the antimuscarinic agents tolterodine tartrate ER and oxybutynin chloride ER on recent memory in older subjects Neurourol Urodyn 25 615
-
(2006)
Neurourol Urodyn
, vol.25
, pp. 615
-
-
Kay, G.1
Kardiasmenos, K.2
Crook, T.3
-
31
-
-
0344874652
-
Transient Memory Impairment and Hallucinations Associated with Tolterodine Use [8]
-
DOI 10.1056/NEJM200312043492325
-
JW Tsao KM Heilman 2003 Transient memory impairment and hallucinations associated with tolterodine use N Engl J Med 349 23 2274 5 14657444 10.1056/NEJM200312043492325 1:CAS:528:DC%2BD3sXps1eitb4%3D (Pubitemid 37485153)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.23
, pp. 2274-2275
-
-
Tsao, J.W.1
Heilman, K.M.2
-
33
-
-
7444229179
-
Hallucinations with tolterodine
-
15534031 10.1176/appi.ps.55.11.1318-a
-
SG Williams J Staudenmeier 2004 Hallucinations with tolterodine Psychiatr Serv 55 11 1318 9 15534031 10.1176/appi.ps.55.11.1318-a
-
(2004)
Psychiatr Serv
, vol.55
, Issue.11
, pp. 1318-9
-
-
Williams, S.G.1
Staudenmeier, J.2
-
34
-
-
0038665188
-
Tolterodine and memory: Dry but forgetful
-
DOI 10.1001/archneur.60.5.771
-
KB Womack KM Heilman 2003 Tolterodine and memory: dry but forgetful Arch Neurol 60 5 771 3 12756144 10.1001/archneur.60.5.771 (Pubitemid 36569899)
-
(2003)
Archives of Neurology
, vol.60
, Issue.5
, pp. 771-773
-
-
Womack, K.B.1
Heilman, K.M.2
-
35
-
-
1342331401
-
Randomized, double-blind placebo-and tolterodine-controlled trial of the once-daily antimuscarinic agent solifenacin in patients with symptomatic overactive bladder
-
DOI 10.1111/j.1464-410X.2004.04606.x
-
CR Chapple T Rechberger S Al-Shukri P Meffan K Everaert M Huang A Ridder 2004 Randomized, double-blind placebo- and tolterodine-controlled trial of the once-daily antimuscarinic agent solifenacin in patients with symptomatic overactive bladder BJU Int 93 3 303 10 14764127 10.1111/j.1464-410X.2004.04606.x 1:CAS:528:DC%2BD2cXis1ShsLo%3D (Pubitemid 38253574)
-
(2004)
BJU International
, vol.93
, Issue.3
, pp. 303-310
-
-
Chapple, C.R.1
Rechberger, T.2
Al-Shukri, S.3
Meffan, P.4
Everaert, K.5
Huang, M.6
Ridder, A.7
-
36
-
-
33646770677
-
Efficacy and tolerability of solifenacin in elderly subjects with overactive bladder syndrome: A pooled analysis
-
16730617 10.1016/j.amjopharm.2006.03.004 1:CAS:528:DC%2BD28Xht1aktbnK
-
A Wagg JJ Wyndaele P Sieber 2006 Efficacy and tolerability of solifenacin in elderly subjects with overactive bladder syndrome: a pooled analysis Am J Geriatr Pharmacother 4 1 14 24 16730617 10.1016/j.amjopharm.2006.03.004 1:CAS:528:DC%2BD28Xht1aktbnK
-
(2006)
Am J Geriatr Pharmacother
, vol.4
, Issue.1
, pp. 14-24
-
-
Wagg, A.1
Wyndaele, J.J.2
Sieber, P.3
-
37
-
-
80755156131
-
Solifenacin is not associated with cognitive impairment or sedation in the elderly: The randomized, double-blind SCOPE study
-
Birmingham, UK: Poster 68
-
Wesnes KA EC, Tretter RN, Patel H, Bolodeoku J. Solifenacin is not associated with cognitive impairment or sedation in the elderly: the randomized, double-blind SCOPE study. Br Geriatr Soc (Autumn Meeting). 2008; Birmingham, UK: Poster 68
-
(2008)
Br Geriatr Soc (Autumn Meeting)
-
-
Wesnes, K.A.E.C.1
Tretter, R.N.2
Patel, H.3
Bolodeoku, J.4
-
38
-
-
23944480846
-
3 selective receptor antagonist
-
DOI 10.1016/j.eururo.2005.05.009, PII S0302283805003027
-
J Foote K Glavind G Kralidis JJ Wyndaele 2005 Treatment of overactive bladder in the older patient: pooled analysis of three phase III studies of darifenacin, an M3 selective receptor antagonist Eur Urol 48 3 471 7 15990219 10.1016/j.eururo.2005.05.009 (Pubitemid 41188407)
-
(2005)
European Urology
, vol.48
, Issue.3
, pp. 471-477
-
-
Foote, J.1
Glavind, K.2
Kralidis, G.3
Wyndaele, J.-J.4
-
39
-
-
35648994890
-
Darifenacin treatment of patients ≥ 65 years with overactive bladder: Results of a randomized, controlled, 12-week trial
-
DOI 10.1185/03007X226294
-
C Chapple C DuBeau U Ebinger L Rekeda A Viegas 2007 Darifenacin treatment of patients > or = 65 years with overactive bladder: results of a randomized, controlled, 12-week trial Curr Med Res Opin 23 10 2347 58 17706004 10.1185/03007X226294 1:CAS:528:DC%2BD2sXhtlektLzO (Pubitemid 350033436)
-
(2007)
Current Medical Research and Opinion
, vol.23
, Issue.10
, pp. 2347-2358
-
-
Chapple, C.1
DuBeau, C.2
Ebinger, U.3
Rekeda, L.4
Viegas, A.5
-
40
-
-
12544253619
-
Assessment of cognitive function of the elderly population: Effects of darifenacin
-
15643227 10.1097/01.ju.0000148963.21096.5d
-
RB Lipton K Kolodner K Wesnes 2005 Assessment of cognitive function of the elderly population: effects of darifenacin J Urol 173 2 493 8 15643227 10.1097/01.ju.0000148963.21096.5d
-
(2005)
J Urol
, vol.173
, Issue.2
, pp. 493-8
-
-
Lipton, R.B.1
Kolodner, K.2
Wesnes, K.3
-
41
-
-
26844464517
-
3 selective receptor antagonist for the treatment of overactive bladder, in healthy volunteers
-
DOI 10.1111/j.1464-410X.2005.05745.x
-
GG Kay KA Wesnes 2005 Pharmacodynamic effects of darifenacin, a muscarinic M selective receptor antagonist for the treatment of overactive bladder, in healthy volunteers BJU Int 96 7 1055 62 16225528 10.1111/j.1464-410X.2005.05745.x 1:CAS:528:DC%2BD2MXht1amtLnF (Pubitemid 41531414)
-
(2005)
BJU International
, vol.96
, Issue.7
, pp. 1055-1062
-
-
Kay, G.G.1
Wesnes, K.A.2
-
42
-
-
48049117725
-
Fesoterodine: A novel muscarinic receptor antagonist for the treatment of overactive bladder syndrome
-
18570610 10.1517/14656566.9.10.1787 1:CAS:528:DC%2BD1cXnsFeitL8%3D
-
MC Michel 2008 Fesoterodine: a novel muscarinic receptor antagonist for the treatment of overactive bladder syndrome Expert Opin Pharmacother 9 10 1787 96 18570610 10.1517/14656566.9.10.1787 1:CAS:528:DC%2BD1cXnsFeitL8%3D
-
(2008)
Expert Opin Pharmacother
, vol.9
, Issue.10
, pp. 1787-96
-
-
Michel, M.C.1
-
43
-
-
53849143605
-
Comparison of fesoterodine and tolterodine in patients with overactive bladder
-
18647298 10.1111/j.1464-410X.2008.07907.x 1:CAS:528:DC%2BD1cXhsFSjs7bF
-
CR Chapple PE Van Kerrebroeck KP Junemann JT Wang M Brodsky 2008 Comparison of fesoterodine and tolterodine in patients with overactive bladder BJU Int 102 9 1128 32 18647298 10.1111/j.1464-410X.2008.07907.x 1:CAS:528:DC%2BD1cXhsFSjs7bF
-
(2008)
BJU Int
, vol.102
, Issue.9
, pp. 1128-32
-
-
Chapple, C.R.1
Van Kerrebroeck, P.E.2
Junemann, K.P.3
Wang, J.T.4
Brodsky, M.5
-
44
-
-
78649906797
-
Efficacy and tolerability of fesoterodine in older and younger subjects with overactive bladder
-
20974482 10.1016/j.urology.2010.03.097
-
SR Kraus JL Ruiz-Cerda D Martire JT Wang AS Wagg 2010 Efficacy and tolerability of fesoterodine in older and younger subjects with overactive bladder Urology 76 6 1350 7 20974482 10.1016/j.urology.2010.03.097
-
(2010)
Urology
, vol.76
, Issue.6
, pp. 1350-7
-
-
Kraus, S.R.1
Ruiz-Cerda, J.L.2
Martire, D.3
Wang, J.T.4
Wagg, A.S.5
-
45
-
-
77954647114
-
Trospium chloride has no effect on memory testing and is assay undetectable in the central nervous system of older patients with overactive bladder
-
20561092 10.1111/j.1742-1241.2010.02433.x 1:CAS:528:DC%2BC3cXhtFKrtbnN The SMART trial demonstrated the absence of adverse effects on memory testing in older patients as well as the absence of trospium in these patients' cerebrospinal fluid
-
D Staskin G Kay C Tannenbaum HB Goldman K Bhashi J Ling MG Oefelein 2010 Trospium chloride has no effect on memory testing and is assay undetectable in the central nervous system of older patients with overactive bladder Int J Clin Pract 64 9 1294 300 20561092 10.1111/j.1742-1241.2010.02433.x 1:CAS:528:DC%2BC3cXhtFKrtbnN The SMART trial demonstrated the absence of adverse effects on memory testing in older patients as well as the absence of trospium in these patients' cerebrospinal fluid
-
(2010)
Int J Clin Pract
, vol.64
, Issue.9
, pp. 1294-300
-
-
Staskin, D.1
Kay, G.2
Tannenbaum, C.3
Goldman, H.B.4
Bhashi, K.5
Ling, J.6
Oefelein, M.G.7
-
46
-
-
79551543569
-
Trospium chloride once-daily extended release is efficacious and tolerated in elderly subjects (aged >/= 75 years) with overactive bladder syndrome
-
20707790 10.1111/j.1464-410X.2010.09519.x The authors of this article analyzed pooled data from two phase 3 trials of trospium chloride and demonstrated efficacy and tolerability in elderly patients
-
PK Sand TM Johnson Ii ES Rovner PI Ellsworth MG Oefelein DR Staskin 2010 Trospium chloride once-daily extended release is efficacious and tolerated in elderly subjects (aged >/= 75 years) with overactive bladder syndrome BJU Int 107 4 612 20 20707790 10.1111/j.1464-410X.2010.09519.x The authors of this article analyzed pooled data from two phase 3 trials of trospium chloride and demonstrated efficacy and tolerability in elderly patients
-
(2010)
BJU Int
, vol.107
, Issue.4
, pp. 612-20
-
-
Sand, P.K.1
Johnson Ii, T.M.2
Rovner, E.S.3
Ellsworth, P.I.4
Oefelein, M.G.5
Staskin, D.R.6
-
47
-
-
77955247789
-
Trospium chloride is undetectable in the older human central nervous system
-
20942892 10.1111/j.1532-5415.2010.02988.x
-
D Staskin G Kay C Tannenbaum HB Goldman K Bhashi J Ling MG Oefelein 2010 Trospium chloride is undetectable in the older human central nervous system J Am Geriatr Soc 58 8 1618 9 20942892 10.1111/j.1532-5415.2010.02988.x
-
(2010)
J Am Geriatr Soc
, vol.58
, Issue.8
, pp. 1618-9
-
-
Staskin, D.1
Kay, G.2
Tannenbaum, C.3
Goldman, H.B.4
Bhashi, K.5
Ling, J.6
Oefelein, M.G.7
-
48
-
-
16644383514
-
Effect of trospium chloride on somnolence and sleepiness in patients with overactive bladder
-
15541209 10.1007/s11934-004-0064-0
-
DR Staskin MD Harnett 2004 Effect of trospium chloride on somnolence and sleepiness in patients with overactive bladder Curr Urol Rep 5 6 423 6 15541209 10.1007/s11934-004-0064-0
-
(2004)
Curr Urol Rep
, vol.5
, Issue.6
, pp. 423-6
-
-
Staskin, D.R.1
Harnett, M.D.2
-
49
-
-
79551526873
-
Once-daily trospium chloride 60 mg extended release in subjects with overactive bladder syndrome who use multiple concomitant medications: Post hoc analysis of pooled data from two randomized, placebo-controlled trials
-
21275440 10.2165/11586740-000000000-00000 1:CAS:528:DC%2BC3MXjsFOmurs%3D
-
PK Sand ES Rovner JH Watanabe MG Oefelein 2011 Once-daily trospium chloride 60 mg extended release in subjects with overactive bladder syndrome who use multiple concomitant medications: post hoc analysis of pooled data from two randomized, placebo-controlled trials Drugs Aging 28 2 151 60 21275440 10.2165/11586740-000000000-00000 1:CAS:528:DC%2BC3MXjsFOmurs%3D
-
(2011)
Drugs Aging
, vol.28
, Issue.2
, pp. 151-60
-
-
Sand, P.K.1
Rovner, E.S.2
Watanabe, J.H.3
Oefelein, M.G.4
-
50
-
-
2042476079
-
Treatment of urinary incontinence with anticholinergics in patients taking cholinesterase inhibitors for dementia
-
DOI 10.1016/j.clpt.2004.01.015, PII S0009923604000402
-
EL Siegler M Reidenberg 2004 Treatment of urinary incontinence with anticholinergics in patients taking cholinesterase inhibitors for dementia Clin Pharmacol Ther 75 5 484 8 15116061 10.1016/j.clpt.2004.01.015 1:CAS:528:DC%2BD2cXjs1CjtbY%3D (Pubitemid 38534569)
-
(2004)
Clinical Pharmacology and Therapeutics
, vol.75
, Issue.5
, pp. 484-488
-
-
Siegler, E.L.1
Reidenberg, M.2
-
51
-
-
0036081737
-
Risk of delirium with concomitant use of tolterodine and acetylcholinesterase inhibitors [3]
-
DOI 10.1046/j.1532-5415.2002.50281.x
-
KR Edwards JT O'Connor 2002 Risk of delirium with concomitant use of tolterodine and acetyl cholinesterase inhibitors J Am Geriatr Soc 50 6 1165 6 12110086 10.1046/j.1532-5415.2002.50281.x (Pubitemid 34666332)
-
(2002)
Journal of the American Geriatrics Society
, vol.50
, Issue.6
, pp. 1165-1166
-
-
Edwards, K.R.1
O'Connor, J.T.2
-
52
-
-
43249100527
-
Dual use of bladder anticholinergics and cholinesterase inhibitors: Long-term functional and cognitive outcomes
-
DOI 10.1111/j.1532-5415.2008.01681.x
-
KM Sink J Thomas 3rd H Xu B Craig S Kritchevsky LP Sands 2008 Dual use of bladder anticholinergics and cholinesterase inhibitors: long-term functional and cognitive outcomes J Am Geriatr Soc 56 5 847 53 18384584 10.1111/j.1532-5415.2008.01681.x The results of this study demonstrated greater functional decline in previously high-functioning nursing home residents taking both an antimuscarinic and cholinesterase inhibitor (Pubitemid 351652414)
-
(2008)
Journal of the American Geriatrics Society
, vol.56
, Issue.5
, pp. 847-853
-
-
Sink, K.M.1
Thomas III, J.2
Xu, H.3
Craig, B.4
Kritchevsky, S.5
Sands, L.P.6
-
53
-
-
41049092868
-
Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivo
-
DOI 10.1111/j.1464-410X.2007.07358.x
-
P Ney RK Pandita DT Newgreen A Breidenbach T Stohr KE Andersson 2008 Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivo BJU Int 101 1036 42 18279452 10.1111/j.1464-410X.2007.07358.x 1:CAS:528:DC%2BD1cXmtFOmsLY%3D (Pubitemid 351422555)
-
(2008)
BJU International
, vol.101
, Issue.8
, pp. 1036-1042
-
-
Ney, P.1
Pandita, R.K.2
Newgreen, D.T.3
Breidenbach, A.4
Stohr, T.5
Andersson, K.-E.6
|