An electrostatic charge partitioning model for the dissociation of protein complexes in the gas phase

Journal of the American Society for Mass Spectrometry

Volumn 22, Issue 10, 2011, Pages 1679-1689

  Sciuto, Stephen V ^a   Liu, Jiangjiang ^a   Konermann, Lars ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Asymmetric charge partitioning; Electrospray mass spectrometry; Hemoglobin; Noncovalent interaction; Protein complex

Indexed keywords

ASYMMETRIC BEHAVIORS; ASYMMETRIC CHARGE PARTITIONING; CHARGE ACCUMULATION; CHARGE CONFIGURATION; COLLISIONAL ACTIVATION; CONFORMATIONAL CHANGE; DISSOCIATION PROCESS; ELECTROSPRAY MASS SPECTROMETRY; ELECTROSTATIC CHARGES; ELECTROSTATIC MODELS; FINITE DIFFERENCE; GASPHASE; GRADIENT ALGORITHM; MODEL PREDICTION; MULTI-PROTEIN COMPLEX; NON-COVALENT INTERACTION; PHYSICAL CONTACTS; POINT STRUCTURE; PROTEIN COMPLEX; PROTEIN COMPLEXES; QUANTITATIVE COMPARISON; STRUCTURAL CHANGE;

COMPLEXATION; DISSOCIATION; ELECTROSTATICS; GASES; MASS SPECTROMETRY;

PROTEINS;

BETA LACTOGLOBULIN; HEMOGLOBIN; MULTIPROTEIN COMPLEX;

ALGORITHM; ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISSOCIATION; ENERGY YIELD; GAS; ION TRANSPORT; MASS SPECTROMETRY; MATHEMATICAL COMPUTING; NONHUMAN; PHASE PARTITIONING; PROCESS DEVELOPMENT; PROCESS MODEL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; SIMULATION; STATIC ELECTRICITY; STRUCTURE ANALYSIS; SURFACE CHARGE;

ANIMALS; CATTLE; COMPUTER SIMULATION; GASES; HEMOGLOBINS; LACTOGLOBULINS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; PROTEIN UNFOLDING; PROTEINS; PROTONS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STATIC ELECTRICITY; TANDEM MASS SPECTROMETRY;

EID: 80755189415     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0205-x     Document Type: Article

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