Adefovir induced hypophosphatemic osteomalacia

Scandinavian Journal of Infectious Diseases

Volumn 43, Issue 11-12, 2011, Pages 990-992

  Fabbriciani, Gianluigi ^a   De Socio, Giuseppe Vittorio L ^b   Massarotti, Marco ^a   Ceriani, Roberto ^c   Marasini, Bianca ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SANTA MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

^c HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ADEFOVIR DIPIVOXIL; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CALCIFEDIOL; CALCIUM; COLECALCIFEROL; CREATININE; ENTECAVIR; INTERFERON; OSTEOCALCIN; PARATHYROID HORMONE; PHOSPHATE; RIBAVIRIN;

ADULT; AGED; BODY MASS; BONE DENSITOMETRY; BONE PAIN; BONE SCINTISCANNING; CASE REPORT; DISEASE SEVERITY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DUAL ENERGY X RAY ABSORPTIOMETRY; FANCONI RENOTUBULAR SYNDROME; GAIT DISORDER; HEPATITIS B; HUMAN; HYPOPHOSPHATEMIA; HYPOPHOSPHATEMIC RICKETS; HYPOURICEMIA; LETTER; MALE; SINGLE DRUG DOSE; VITAMIN DEFICIENCY;

ADENINE; AGED; HUMANS; HYPOPHOSPHATEMIA; MALE; OSTEOMALACIA; PHOSPHONIC ACIDS; RADIONUCLIDE IMAGING; WHOLE BODY IMAGING;

EID: 80755171299     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2011.581307     Document Type: Letter

References (13)

1. Izzedine H, Hulot JS, Launay-Vacher V, Marcellini P, Hadziyannis SJ, Currie G, et al. Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: Two doubleblind, randomized, placebo-controlled studies. Kidney Int 2004;66:1153-8. (Pubitemid 39121022)
2. Fontana RJ. Side effects of long-term oral antiviral therapy for hepatitis B. Hepatology 2009;49(Suppl):185-95.
3. Fux CA, Rauch A, Simcock M, Bucher HC, Hirschel B, Opravil M, et al. Tenofovir use is associated with an increase in serum alkaline phosphatase in the Swiss HIV Cohort Study. Antivir Ther 2008;13:1077-82.
4. Lee HJ, Choi JW, Kim TN, Eun JR. A case of severe hypophosphatemia related to adefovir dipivoxil treatment in a patient with liver cirrhosis related to hepatitis B virus. Korean J Hepatol 2008;14:381-6.
5. Izzedine H, Kheder-Elfekih R, Housset P, Sarkozy C, Brocheriou I, Deray G. Adefovir dipivoxil-induced acute tubular necrosis and Fanconi syndrome in a renal transplant patient. AIDS 2009;23:544-5.
6. Wong T, Girgis CM, Ngu MC, Chen RC, Emmett L, Archer KA, et al. Hypophosphatemic osteomalacia after low-dose adefovir dipivoxil therapy for hepatitis B. J Clin Endocrinol Metab 2010;95:479-80.
7. Girgis CM, Wong T, Ngu MC, Emmett L, Archer KA, Chen RC, et al. Hypophosphataemic osteomalacia in patients on adefovir dipivoxil. J Clin Gastroenterol 2011;45:468-73.
8. Minemura M, Tokimitsu Y, Tajiri K, Nakayama Y, Kawai K, Kudo H, et al. Development of osteomalacia in a post-liver transplant patient receiving adefovir dipivoxil. World J Hepatol 2010;2:442-6.
9. Jung YK, Yeon JE, Choi JH, Kim CH, Jung ES, Kim JH, et al. Fanconi ' s syndrome associated with prolonged adefovir dipivoxil therapy in a hepatitis B virus patient. Gut Liver 2010;4:389-93.
10. Kwon SY, Ahn SY, Ko SY, Jang YM, Choi YH, Kim BK, et al. A case of osteomalacia related to adefovir in a patient with chronic hepatitis B. Korean J Gastroenterol 2010;56: 117-20.
11. Santer R, Schneppenheim R, Suter D, Schaub J, Steinmann B. Fanconi - Bickel syndrome - the original patient and his natural history, historical steps leading to the primary defect, and a review of the literature. Eur J Pediatr 1998;157: 783-97. (Pubitemid 28460736)
12. Holick MF. Vitamin D defi ciency. N Engl J Med 2007; 357:266-81.
13. Lips P, van Schoor NM, Bravenboer N. Vitamin D-related disorders. In: Rosen CJ, editor. Primer of the metabolic bone diseases and disorders of mineral metabolism. Scarborough, ME: American Society for Bone and Mineral Research; 2008 pp 329 - 35.