Increased neuron number and head size in autism

JAMA

Volumn 306, Issue 18, 2011, Pages 2031-2032

  Lainhart, Janet E ^a   Lange, Nicholas ^b  

^a The Brain Institute at the University of Utah   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALEXANDER DISEASE; APOPTOSIS; AUTISM; BRAIN CELL; BRAIN GROWTH; BRAIN REGION; BRAIN SIZE; BRAIN WEIGHT; CELL COUNT; CHILD; CHILD PSYCHIATRY; EDITORIAL; HUMAN; MACROCEPHALY; NEUROPATHOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; TEMPORAL LOBE;

EID: 80755169819     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2011.1633     Document Type: Editorial

References (13)

1. Courchesne E, Mouton PR, Calhoun ME, et al. Neuron number and size in prefrontal cortex of children with autism. JAMA. 2011;306(18):2001-2010.
2. Kanner L. Autistic disturbances of affective contact. Nervous Child. 1943; 2:217-250.
3. Lainhart JE, Lange N. The biological broader autism phenotype. In: Amaral DG, Dawson G, Geschwind D, eds. Autism Spectrum Disorders. New York, NY: Oxford University Press; 2011.
4. Lainhart JE, Piven J, Wzorek M, et al. Macrocephaly in children and adults with autism. J Am Acad Child Adolesc Psychiatry. 1997;36(2):282-290. (Pubitemid 27049578)
5. Sparks BF, Friedman SD, Shaw DW, et al. Brain structural abnormalities in young children with autism spectrum disorder. Neurology. 2002;59(2):184-192. (Pubitemid 34779175)
6. Schumann CM, Bloss CS, Carter Barnes C, et al. Longitudinal MRI study of cortical development through early childhood in autism. J Neurosci. 2010;30(12): 4419-4427.
7. Hazlett HC, Poe MD, Gerig G, et al. Early brain overgrowth in autism associated with an increase in cortical surface area before age 2 years. Arch Gen Psychiatry. 2011;68(5):467-476.
8. Benes FM, Lange N. Two-dimensional versus three-dimensional cell counting: a practical perspective. Trends Neurosci. 2001;24(1):11-17. (Pubitemid 32332892)
9. Brain Development Cooperative Group; Lange N. Total and regional brain volumes in a population-based normative sample from 4 to 18 years: the NIH MRI study of normal brain development [published online May 25, 2011]. Cereb Cortex. 2011. doi:10.1093/cercor/bhr018.
10. Rakic P. A century of progress in corticoneurogenesis: from silver impregnation to genetic engineering. Cereb Cortex. 2006;16(suppl 1):i3-i17.
11. Fraser MM, Bayazitov B, Zakharenko SS, Baker SJ. PTEN deficiency in brain causes severe defects in synaptic structure, transmission and plasticity and myelination abnormalities. Neuroscience. 2008;151(2):476-488.
12. Lange N, Dubray MB, Lee JE, et al. Atypical diffusion tensor hemispheric asymmetry in autism. Autism Res. 2010;3(6):350-358.
13. Kanner L. Follow-up study of eleven autistic children originally reported in 1943. J Autism Child Schizophr. 1971;1(2):119-145.