Pharmacokinetics and metabolism of N-[N-[3-(3-hydroxy-4-methoxyphenyl) propyl]-α-aspartyl]-l-phenylalanine 1-methyl ester, monohydrate (advantame) in the rat, dog, and man

Food and Chemical Toxicology

Volumn 49, Issue SUPPL. 1, 2011, Pages

  Ubukata, K ^a   Nakayama, A ^a   Mihara, R ^a  

^a AJINOMOTO CO INC   (Japan)

Author keywords

Advantame; Dog; Human; Metabolism; Pharmacokinetics; Rat

Indexed keywords

3 [3 HYDROXY 4 METHOXYPHENYL] 1 PROPYLAMINE; ADVANTAME; CARBON 14; N [3 (3 HYDROXY 4 METHOXYPHENYL)]PROPYL ASPARTIC ACID; PROPYLAMINE; SWEETENING AGENT; UNCLASSIFIED DRUG;

ABSORPTION; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; BLOOD LEVEL; CLEARANCE; CONTROLLED STUDY; DOG; EXCRETION; FECES LEVEL; FEMALE; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HYDROLYSIS; MALE; NONHUMAN; NORMAL HUMAN; RADIOACTIVITY; RAT; SOLID PHASE EXTRACTION; SPECIES DIFFERENCE; THIN LAYER CHROMATOGRAPHY; URINE LEVEL;

ADMINISTRATION, ORAL; ADULT; ANIMALS; AREA UNDER CURVE; DIPEPTIDES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HALF-LIFE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; METALLOPORPHYRINS; MIDDLE AGED; RATS; SPECIES SPECIFICITY; SWEETENING AGENTS;

ANIMALIA; CANIS FAMILIARIS; RATTUS;

EID: 80755166117     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.06.042     Document Type: Article

References (15)

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