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These are the current ACC/AHA guidelines for managing AF
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Wann LS, Curtis AB, January CT, Ellenbogen KA, Lowe JE, Estes NA 3rd, et al. 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Heart Rhythm. 2011;8(1):157-76. These are the current ACC/AHA guidelines for managing AF.
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Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: A randomized controlled trial
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thermocool AF trial compared irrigated AF ablation to antiarrhythmic therapy in a prospective randomized trial and found an overwhelming outcome in favor of ablation. This trial led to approval of the thermocool catheter for AF ablation by the US Food and Drug Administration
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Wilber DJ, Pappone C, Neuzil P, De Paola A, Marchlinski F, Natale A, et al. Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial. JAMA 2010;303:333-40. The thermocool AF trial compared irrigated AF ablation to antiarrhythmic therapy in a prospective randomized trial and found an overwhelming outcome in favor of ablation. This trial led to approval of the thermocool catheter for AF ablation by the US Food and Drug Administration.
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Catheter ablation versus antiarrhythmic drug therapy for atrial fibrillation - Pilot trial
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Abstract. The CABANA pilot trial compared catheter ablation and medical management of AF in a small, prospective randomized trial. The larger randomized trial is now underway
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Packer DL, Lee KL, Mark DB, Monahan KH, Hoffmann KL, Hafley GE, et al. Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation - Pilot Trial. J Amer Coll Cardiol 2010; Abstract. The CABANA pilot trial compared catheter ablation and medical management of AF in a small, prospective randomized trial. The larger randomized trial is now underway.
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Cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation: First results of the North American arctic front stop-AF trial
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Abstract 3015-6, The Stop-AF trial compared cryoballoon ablation to antiarrhythmic therapy for treating AF
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Packer D, et al. Cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation: first results of the North American Arctic Front Stop-AF trial. J Amer Coll Cardiol. 2010; Abstract 3015-6. The Stop-AF trial compared cryoballoon ablation to antiarrhythmic therapy for treating AF.
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Reddy VY, Neuzil P, D'Avila A, Laragy M, Malchano ZJ, Kralovec S, et al. Balloon catheter ablation to treat paroxysmal atrial fibrillation: what is the level of pulmonary venous isolation? Hear Rhythm. 2008;5(3):353-60.
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