Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice

Archives of Toxicology

Volumn 85, Issue 10, 2011, Pages 1245-1256

  Abdel Bakky, Mohamed Sadek ^a,c   Hammad, Mohamed A ^a,b,d   Walker, Larry A ^a,b   Ashfaq, Mohammad K ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c Al Azhar University   (Egypt)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Lipopolysaccharide; Monocrotaline; Renal toxicity; Tissue factor antisense

Indexed keywords

ALKALINE PHOSPHATASE; ANTISENSE OLIGODEOXYNUCLEOTIDE; CREATININE; CXCL16 CHEMOKINE; FIBRIN; INTERLEUKIN 6; LEPTIN; LIPOPOLYSACCHARIDE; MONOCROTALINE; NITROGEN DERIVATIVE; POTASSIUM; THROMBOPLASTIN; UNCLASSIFIED DRUG; UREA NITROGEN;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; GLOMERULUS CAPILLARY; HISTOPATHOLOGY; KIDNEY CORTEX; KIDNEY INJURY; KIDNEY MEDULLA; KIDNEY TUBULE NECROSIS; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PATHOGENESIS; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN INDUCTION; SURVIVAL RATE; UREA NITROGEN BLOOD LEVEL;

ACUTE KIDNEY INJURY; ALKALINE PHOSPHATASE; ANIMALS; BLOOD UREA NITROGEN; CHEMOKINE CXCL6; CREATININE; FIBRIN; INTERLEUKIN-6; KIDNEY; LEPTIN; LIPOPOLYSACCHARIDES; MALE; MICE; MONOCROTALINE; OLIGONUCLEOTIDES, ANTISENSE; POTASSIUM; THROMBOPLASTIN;

ANIMALIA; MUS;

EID: 80755135569     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0663-8     Document Type: Article

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