Endothelin-1 stimulates proliferation of first-trimester trophoblasts via the A- and B-type receptor and invasion via the B-type receptor

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 11, 2011, Pages 3408-3415

  Cervar Zivkovic, M ^a   Dieber Rotheneder, M ^a   Barth, S ^a   Hahn, T ^a   Kohnen, G ^b   Huppertz, B ^a   Lang, U ^a   Desoye, G ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BQ 610; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; N ACETYL 3,3 DIPHENYL DEXTRO ALANYLLEUCYLASPARTYLISOLEUCYLISOLEUCYLTRYPTOPHAN; RES 701 1;

ARTICLE; AUTORADIOGRAPHY; CELL INVASION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MITOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TROPHOBLAST; WESTERN BLOTTING;

CELL MOVEMENT; CELL PROLIFERATION; DOWN-REGULATION; ENDOTHELIN-1; FEMALE; HUMANS; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, FIRST; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RNA, MESSENGER; TROPHOBLASTS;

EID: 80655148283     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-0634     Document Type: Article

References (33)

1. Frank HG, Kaufmann P 2006 Nonvillous parts and trophoblast invasion. In: Benirschke K, Kaufmann P, Baergen RN, eds. Pathology of the human placenta. 5th ed. New York: Springer; 204-206
2. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T 1988 A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415 (Pubitemid 18090241)
3. Cervar M, Puerstner P, Kainer F, Desoye G 1996 Endothelin-1 stimulates the proliferation and invasion of first trimester trophoblastic cells in vitro-a possible role in the etiology of pre-eclampsia? J Investig Med 44:447-453 (Pubitemid 126820693)
4. i and phosphorylation of MAP kinase of a human extravillous trophoblast cell line. Mol Cell Endocrinol 201:63-73
5. Yohn JJ, Smith C, Stevens T, Hoffman TA, Morelli JG, Hurt DL, Yanagisawa M, Kane MA, Zamora MR 1994 Human melanoma cells express functional endothelin-1 receptors. Biochem Biophys Res Commun 201:449-457 (Pubitemid 24213747)
6. Cervar M, Kainer F, Jones CJ, Desoye G 1996 Altered release of endothelin-1,2 and thromboxane B2 from trophoblastic cells in preeclampsia. Eur J Clin Invest 26:30-37 (Pubitemid 26046786)
7. Miyamoto Y, Yoshimasa T, Arai H, Takaya K, Ogawa Y, Itoh H, Nakao K 1996 Alternative RNA splicing of the human endothelin-A receptor generates multiple transcripts. Biochem J 313(Pt 3):795-801 (Pubitemid 26050810)
8. Elshourbagy NA, Korman DR, Wu HL, Sylvester DR, Lee JA, Nuthalaganti P, Bergsma DJ, Kumar CS, Nambi P 1993 Molecular characterization and regulation of the human endothelin receptors. J Biol Chem 268:3873-3879 (Pubitemid 23072916)
9. Cervar M, Huppertz B, Barth S, Hahn T, Weiss U, Kaufmann P, Desoye G 2000 Endothelin A and B receptors change their expression levels during development of human placental villi. Placenta 21:536-546 (Pubitemid 30608596)
10. Fukuroda T, Fujikawa T, Ozaki S, Ishikawa K, Yano M, Nishikibe M 1994 Clearance of circulating endothelin-1 by ETB receptors in rats. Biochem Biophys Res Commun 199:1461-1465
11. Muramatsu M, Oka M, Morio Y, Soma S, Takahashi H, Fukuchi Y 1999 Chronic hypoxia augments endothelin-B receptor-mediated vasodilation in isolated perfused rat lungs.AmJ Physiol 276:L358-L364 (Pubitemid 29102278)
12. Verhaar MC, Strachan FE, Newby DE, Cruden NL, Koomans HA, Rabelink TJ, Webb DJ 1998 Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade. Circulation 97:752-756 (Pubitemid 28135337)
13. Rosanò L, Spinella F, Salani D, Di Castro V, Venuti A, Nicotra MR, Natali PG, Bagnato A 2003 Therapeutic targeting of the endothelin a receptor in human ovarian carcinoma. Cancer Res 63:2447-2453 (Pubitemid 36605182)
14. Eberle J, Fecker LF, Orfanos CE, Geilen CC 2002 Endothelin-1 decreases basic apoptotic rates in human melanoma cell lines. J Invest Dermatol 119:549-555
15. Morris CD, Rose A, Curwen J, Hughes AM, Wilson DJ, Webb DJ 2005 Specific inhibition of the endothelin A receptor with ZD4054: clinical and pre-clinical evidence. Br J Cancer 92:2148-2152 (Pubitemid 40966249)
16. Ozaki S, Ohwaki K, Ihara M, Ishikawa K, Yano M 1997 Coexpression studies with endothelin receptor subtypes indicate the existence of intracellular cross-talk between ET(A) and ET(B) receptors. J Biochem 121:440-447 (Pubitemid 27145897)
17. Zhou Y, Damsky CH, Chiu K, Roberts JM, Fisher SJ 1993 Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts. J Clin Invest 91:950-960 (Pubitemid 23095269)
18. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ 1951 Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
19. Dieber-Rotheneder M, Stern C, Desoye G, Cervar-Zivkovic M 2006 Up-regulation of the endothelin receptor A in placental tissue from first trimester delayed miscarriages. J Soc Gynecol Investig 13:435-441 (Pubitemid 46059276)
20. Bilban M, Barth S, Cervar M, Mauschitz R, Schaur RJ, Zivkovic F, Desoye G 2000 Differential regulation of endothelin secretion and endothelin receptor mRNA levels in JAR, JEG-3, and BeWo choriocarcinoma cell lines and in human trophoblasts, their nonmalignant counterpart. Arch Biochem Biophys 382:245-252
21. Nakajo S, Sugiura M, Snajdar RM, Boehm FH, Inagami T 1989 Solubilization and identification of human placental endothelin receptor. Biochem Biophys Res Commun 164:205-211 (Pubitemid 19269716)
22. Ohlstein EH, Arleth A, Bryan H, Elliott JD, Sung CP 1992 The selective endothelin ETA receptor antagonist BQ123 antagonizes endothelin-1-mediated mitogenesis. Eur J Pharmacol 225:347-350
23. Simonson MS, Herman WH 1993 Protein kinase C and protein tyrosine kinase activity contribute to mitogenic signaling by endothelin-1. Cross-talk between G protein-coupled receptors and pp60c-src. J Biol Chem 268:9347-9357 (Pubitemid 23145982)
24. Wang Y, Pouysségur J, Dunn MJ 1994 Endothelin stimulates mitogen- activated protein kinase activity in mesangial cells through ETA. J Am Soc Nephrol 5:1074-1080 (Pubitemid 24977084)
25. Rauh A, Windischhofer W, Kovacevic A, DeVaney T, Huber E, Semlitsch M, Leis HJ, Sattler W, Malle E 2008 Endothelin (ET)-1 and ET-3 promote expression of c-fos and c-jun in human choriocarcinoma via ETB receptor-mediated Gi- and Gq-pathways and MAP kinase activation. Br J Pharmacol 154:13-24 (Pubitemid 351620412)
26. Mallat A, Fouassier L, Préaux AM, Gal CS, Raufaste D, Rosenbaum J, Dhumeaux D, Jouneaux C, Mavier P, Lotersztajn S 1995 Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway. J Clin Invest 96:42-49
27. Lazarini F, Strosberg AD, Couraud PO, Cazaubon SM 1996 Coupling of ETB endothelin receptor to mitogen-activated protein kinase stimulation and DNA synthesis in primary cultures of rat astrocytes. J Neurochem 66:459-465
28. Niger C, Malassiné A, Cronier L 2004 Calcium channels activated by endothelin-1 in human trophoblast. J Physiol 561:449-458 (Pubitemid 39646534)
29. Cervar-Zivkovic M, Hu C, Barton A, Sadovsky Y, Desoye G, Lang U, Nelson DM 2007 Endothelin-1 attenuates apoptosis in cultured trophoblasts from term human placentas. Reprod Sci 14:430-439 (Pubitemid 351168798)
30. Douglas SA, Louden C, Vickery-Clark LM, Storer BL, Hart T, Feuerstein GZ, Elliott JD, Ohlstein EH 1994 A role for endogenous endothelin-1 in neointimal formation after rat carotid artery balloon angioplasty. Protective effects of the novel nonpeptide endothelin receptor antagonist SB 209670. Circ Res 75:190-197
31. Douglas SA, Beck Jr GR, Elliott JD, Ohlstein EH 1995 Pharmacological evidence for the presence of three distinct functional endothelin receptor subtypes in the rabbit lateral saphenous vein. Br J Pharmacol 114:1529-1540
32. Warner TD, Allcock GH, Corder R, Vane JR 1993 Use of the endothelin antagonists BQ-123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF. Br J Pharmacol 110:777-782 (Pubitemid 23279292)
33. Warner TD, Allcock GH, Mickley EJ, Corder R, Vane JR 1993 Comparative studies with the endothelin receptor antagonists BQ- 123 and PD 142893 indicate at least three endothelin receptors. J Cardiovasc Pharmacol 22(Suppl 8):S117-S120 (Pubitemid 24027906)