Quantitative liquid chromatography coupled with tandem mass spectrometry analysis of urinary acylglycines: Application to the diagnosis of inborn errors of metabolism

Analytical Biochemistry

Volumn 417, Issue 1, 2011, Pages 122-128

  Ombrone, Daniela ^a   Salvatore, Francesco ^a   Ruoppolo, Margherita ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Acylglycines; Mitochondrial fatty acid b oxidation defects; Organic acidemias; Tandem mass spectrometry

Indexed keywords

COENZYMES; DEFECTS; DIAGNOSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; MITOCHONDRIA; PROPIONIC ACID;

ACYLGLYCINES; CHROMATOGRAPHIC SEPARATIONS; INBORN ERRORS OF METABOLISMS; LIQUID CHROMATOGRAPHY COUPLED WITH TANDEM MASS SPECTROMETRIES; MULTIPLE REACTION MONITORING; ORGANIC ACIDEMIAS; TANDEM MASS SPECTROMETRY; THROUGHPUT CAPABILITY;

FATTY ACIDS;

GLYCINE DERIVATIVE; N ACYLGLYCINE; UNCLASSIFIED DRUG; GLYCINE;

ARTICLE; BETA KETOTHIOLASE DEFICIENCY; CLINICAL ARTICLE; CONTROLLED STUDY; DERIVATIZATION; HUMAN; INBORN ERROR OF METABOLISM; ISOBUTYRYL COENZYME A DEHYDROGENASE DEFICIENCY; ISOMER; ISOVALERIC ACIDEMIA; LIQUID CHROMATOGRAPHY; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE DEFICIENCY; METABOLITE; MULTIPLE ACYL COA DEHYDROGENASE DEFICIENCY; PRIORITY JOURNAL; PROPIONIC ACIDEMIA; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SHORT BRANCHED CHAIN AMINO ACID DEFICIENCY; TANDEM MASS SPECTROMETRY; URINE; ADOLESCENT; CASE CONTROL STUDY; CHILD; INFANT; METHODOLOGY; NEWBORN; PRESCHOOL CHILD; THERMODYNAMICS; TIME;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, LIQUID; GLYCINE; HUMANS; INFANT; INFANT, NEWBORN; METABOLISM, INBORN ERRORS; TANDEM MASS SPECTROMETRY; THERMODYNAMICS; TIME FACTORS;

EID: 80655147801     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.05.042     Document Type: Article

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