메뉴 건너뛰기




Volumn 35, Issue , 2011, Pages S3-S9

Liver fibrogenesis and genetic factors

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DISEASE COURSE; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC PREDISPOSITION; GENETICS; HOSPITALIZATION; HUMAN; LIVER CIRRHOSIS; MUTATION; PATHOPHYSIOLOGY; PHENOTYPE; PROGNOSIS; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 80655147513     PISSN: 22107401     EISSN: 2210741X     Source Type: Journal    
DOI: 10.1016/S2210-7401(11)70002-X     Document Type: Article
Times cited : (7)

References (69)
  • 3
    • 33846232778 scopus 로고    scopus 로고
    • Non-invasive diagnosis of cirrhosis and the natural history of its complications
    • de Franchis, R., Dell'Era, A., Non-invasive diagnosis of cirrhosis and the natural history of its complications. Best Pract Res Clin Gastroenterol 21 (2007), 3–18.
    • (2007) Best Pract Res Clin Gastroenterol , vol.21 , pp. 3-18
    • de Franchis, R.1    Dell'Era, A.2
  • 4
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups
    • Poynard, T., Bedossa, P., Opolon, P., Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 349 (1997), 825–832.
    • (1997) Lancet , vol.349 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 5
    • 49649118223 scopus 로고    scopus 로고
    • Estimation of stage-specific fibrosis progression rates in chronic hepatitis C virus infection: a meta-analysis and meta-regression
    • Thein, H.H., Yi, Q., Dore, G.J., Krahn, M.D., Estimation of stage-specific fibrosis progression rates in chronic hepatitis C virus infection: a meta-analysis and meta-regression. Hepatology 48 (2008), 418–431.
    • (2008) Hepatology , vol.48 , pp. 418-431
    • Thein, H.H.1    Yi, Q.2    Dore, G.J.3    Krahn, M.D.4
  • 6
    • 77958107011 scopus 로고    scopus 로고
    • Liver fibrosis: from animal models to mapping of human risk variants
    • Weber, S.N., Wasmuth, H.E., Liver fibrosis: from animal models to mapping of human risk variants. Best Pract Res Clin Gastroenterol 24 (2010), 635–646.
    • (2010) Best Pract Res Clin Gastroenterol , vol.24 , pp. 635-646
    • Weber, S.N.1    Wasmuth, H.E.2
  • 7
    • 0033652835 scopus 로고    scopus 로고
    • Chronic liver disease in heterozygous alpha1-antitrypsin deficiency PiZ
    • Fischer, H.P., Ortiz-Pallardo, M.E., Ko, Y., Esch, C., Zhou, H., Chronic liver disease in heterozygous alpha1-antitrypsin deficiency PiZ. J Hepatol 33 (2000), 883–892.
    • (2000) J Hepatol , vol.33 , pp. 883-892
    • Fischer, H.P.1    Ortiz-Pallardo, M.E.2    Ko, Y.3    Esch, C.4    Zhou, H.5
  • 8
    • 33644514365 scopus 로고    scopus 로고
    • HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C
    • Patel, K., Norris, S., Lebeck, L., Feng, A., Clare, M., Pianko, S., Portmann, B., et al. HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C. Hepatology 43 (2006), 241–249.
    • (2006) Hepatology , vol.43 , pp. 241-249
    • Patel, K.1    Norris, S.2    Lebeck, L.3    Feng, A.4    Clare, M.5    Pianko, S.6    Portmann, B.7
  • 10
    • 77951698025 scopus 로고    scopus 로고
    • Genome-wide association studies: present status and future directions
    • e1661
    • Cho, J.H., Genome-wide association studies: present status and future directions. Gastroenterology 138 (2010), 1668–1672 e1661.
    • (2010) Gastroenterology , vol.138 , pp. 1668-1672
    • Cho, J.H.1
  • 11
    • 77951487491 scopus 로고    scopus 로고
    • The utility of genome-wide association studies in hepatology
    • Karlsen, T.H., Melum, E., Fran ke, A., The utility of genome-wide association studies in hepatology. Hepatology 51 (2010), 1833–1842.
    • (2010) Hepatology , vol.51 , pp. 1833-1842
    • Karlsen, T.H.1    Melum, E.2    Fran ke, A.3
  • 13
    • 0031454239 scopus 로고    scopus 로고
    • Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice
    • Clouthier, D.E., Comerford, S.A., Hammer, R.E., Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice. J Clin Invest 100 (1997), 2697–2713.
    • (1997) J Clin Invest , vol.100 , pp. 2697-2713
    • Clouthier, D.E.1    Comerford, S.A.2    Hammer, R.E.3
  • 14
    • 0033109090 scopus 로고    scopus 로고
    • TGF-beta1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis
    • Kanzler, S., Lohse, A.W., Keil, A., Henninger, J., Dienes, H.P., Schirmacher, P., Rose-John, S., et al. TGF-beta1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis. Am J Physiol 276 (1999), G1059–G1068.
    • (1999) Am J Physiol , vol.276 , pp. G1059-G1068
    • Kanzler, S.1    Lohse, A.W.2    Keil, A.3    Henninger, J.4    Dienes, H.P.5    Schirmacher, P.6    Rose-John, S.7
  • 17
    • 27744512904 scopus 로고    scopus 로고
    • Mdr2 (Abcb4) – /– mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes
    • Popov, Y., Patsenker, E., Fickert, P., Trauner, M., Schup pan, D., Mdr2 (Abcb4) – /– mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes. J Hepatol 43 (2005), 1045–1054.
    • (2005) J Hepatol , vol.43 , pp. 1045-1054
    • Popov, Y.1    Patsenker, E.2    Fickert, P.3    Trauner, M.4    Schup pan, D.5
  • 18
    • 0027363563 scopus 로고
    • Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
    • Smit, J.J., Schinkel, A.H., Oude Elferink, R.P., Groen, A.K., Wagenaar, E., van Deemter, L., Mol, C.A., et al. Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75 (1993), 451–462.
    • (1993) Cell , vol.75 , pp. 451-462
    • Smit, J.J.1    Schinkel, A.H.2    Oude Elferink, R.P.3    Groen, A.K.4    Wagenaar, E.5    van Deemter, L.6    Mol, C.A.7
  • 19
    • 36348964151 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis
    • Mencin, A., Seki, E., Osawa, Y., Kodama, Y., De Minicis, S., Knowles, M., Brenner, D.A., Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis. Hepatology 46 (2007), 1443–1452.
    • (2007) Hepatology , vol.46 , pp. 1443-1452
    • Mencin, A.1    Seki, E.2    Osawa, Y.3    Kodama, Y.4    De Minicis, S.5    Knowles, M.6    Brenner, D.A.7
  • 20
    • 0036892365 scopus 로고    scopus 로고
    • Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15
    • Hillebrandt, S., Goos, C., Matern, S., Lam mert, F., Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15. Gastroenterology 123 (2002), 2041–2051.
    • (2002) Gastroenterology , vol.123 , pp. 2041-2051
    • Hillebrandt, S.1    Goos, C.2    Matern, S.3    Lam mert, F.4
  • 22
    • 0037371468 scopus 로고    scopus 로고
    • Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal
    • Bataller, R., North, K.E., Brenner, D.A., Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal. Hepatology 37 (2003), 493–503.
    • (2003) Hepatology , vol.37 , pp. 493-503
    • Bataller, R.1    North, K.E.2    Brenner, D.A.3
  • 23
    • 77149168465 scopus 로고    scopus 로고
    • Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease
    • Dongiovanni, P., Valenti, L., Rametta, R., Daly, A.K., Nobili, V., Mozzi, E., Leathart, J.B., et al. Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease. Gut 59 (2010), 267–273.
    • (2010) Gut , vol.59 , pp. 267-273
    • Dongiovanni, P.1    Valenti, L.2    Rametta, R.3    Daly, A.K.4    Nobili, V.5    Mozzi, E.6    Leathart, J.B.7
  • 24
    • 30544436224 scopus 로고    scopus 로고
    • A combination of genetic polymorphisms increases the risk of progressive disease in chronic hepa titis C
    • Richardson, M.M., Powell, E.E., Barrie, H.D., Clouston, A.D., Purdie, D.M., Jonsson, J.R., A combination of genetic polymorphisms increases the risk of progressive disease in chronic hepa titis C. J Med Genet, 42, 2005, e45.
    • (2005) J Med Genet , vol.42 , pp. e45
    • Richardson, M.M.1    Powell, E.E.2    Barrie, H.D.3    Clouston, A.D.4    Purdie, D.M.5    Jonsson, J.R.6
  • 26
    • 33745279056 scopus 로고    scopus 로고
    • Evaluating coverage of genome-wide association studies
    • Barrett, J.C., Cardon, L.R., Evaluating coverage of genome-wide association studies. Nat Genet 38 (2006), 659–662.
    • (2006) Nat Genet , vol.38 , pp. 659-662
    • Barrett, J.C.1    Cardon, L.R.2
  • 27
    • 77949497074 scopus 로고    scopus 로고
    • Bioinformatics challenges for genome-wide association studies
    • Moore, J.H., Asselbergs, F.W., Williams, S.M., Bioinformatics challenges for genome-wide association studies. Bioinformatics 26 (2010), 445–455.
    • (2010) Bioinformatics , vol.26 , pp. 445-455
    • Moore, J.H.1    Asselbergs, F.W.2    Williams, S.M.3
  • 28
    • 77954407332 scopus 로고    scopus 로고
    • Genomewide association studies and assessment of the risk of disease
    • Manolio, T.A., Genomewide association studies and assessment of the risk of disease. N Engl J Med 363 (2010), 166–176.
    • (2010) N Engl J Med , vol.363 , pp. 166-176
    • Manolio, T.A.1
  • 30
    • 77951731266 scopus 로고    scopus 로고
    • The pursuit of genomewide association studies: where are we now?
    • Ku, C.S., Loy, E.Y., Pawitan, Y., Chia, K.S., The pursuit of genomewide association studies: where are we now?. J Hum Genet 55 (2010), 195–206.
    • (2010) J Hum Genet , vol.55 , pp. 195-206
    • Ku, C.S.1    Loy, E.Y.2    Pawitan, Y.3    Chia, K.S.4
  • 31
    • 34548301514 scopus 로고    scopus 로고
    • A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic he patitis C
    • Huang, H., Shiffman, M.L., Friedman, S., Venkatesh, R., Bzowej, N., Abar, O.T., Rowland, C.M., et al. A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic he patitis C. Hepatology 46 (2007), 297–306.
    • (2007) Hepatology , vol.46 , pp. 297-306
    • Huang, H.1    Shiffman, M.L.2    Friedman, S.3    Venkatesh, R.4    Bzowej, N.5    Abar, O.T.6    Rowland, C.M.7
  • 32
    • 70350054801 scopus 로고    scopus 로고
    • A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic h epatitis C
    • Marcolongo, M., Young, B., Dal Pero, F., Fattovich, G., Peraro, L., Guido, M., Sebastiani, G., et al. A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic h epatitis C. Hepatology 50 (2009), 1038–1044.
    • (2009) Hepatology , vol.50 , pp. 1038-1044
    • Marcolongo, M.1    Young, B.2    Dal Pero, F.3    Fattovich, G.4    Peraro, L.5    Guido, M.6    Sebastiani, G.7
  • 33
    • 73449108399 scopus 로고    scopus 로고
    • The cirrhosis risk score predicts liver fibrosis progression in patients with initially mild chronic hepatitis C
    • Pradat, P., Trepo, E., Potthoff, A., Bakshi, R., Young, B., Trepo, C., Lagier, R., et al. The cirrhosis risk score predicts liver fibrosis progression in patients with initially mild chronic hepatitis C. Hepatology 51 (2010), 356–357.
    • (2010) Hepatology , vol.51 , pp. 356-357
    • Pradat, P.1    Trepo, E.2    Potthoff, A.3    Bakshi, R.4    Young, B.5    Trepo, C.6    Lagier, R.7
  • 34
    • 70450223891 scopus 로고    scopus 로고
    • Common disorders are quantitative traits
    • Plomin, R., Haworth, C.M., Davis, O.S., Common disorders are quantitative traits. Nat Rev Genet 10 (2009), 872–878.
    • (2009) Nat Rev Genet , vol.10 , pp. 872-878
    • Plomin, R.1    Haworth, C.M.2    Davis, O.S.3
  • 35
    • 73449129712 scopus 로고    scopus 로고
    • From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes
    • Wei, Z., Wang, K., Qu, H.Q., Zhang, H., Bradfield, J., Kim, C., Frackleton, E., et al. From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes. PLoS Genet, 5, 2009, e1000678.
    • (2009) PLoS Genet , vol.5 , pp. e1000678
    • Wei, Z.1    Wang, K.2    Qu, H.Q.3    Zhang, H.4    Bradfield, J.5    Kim, C.6    Frackleton, E.7
  • 36
    • 34948877698 scopus 로고    scopus 로고
    • Prediction of individual genetic risk to disease from genome-wide association studies
    • Wray, N.R., Goddard, M.E., Visscher, P.M., Prediction of individual genetic risk to disease from genome-wide association studies. Genome Res 17 (2007), 1520–1528.
    • (2007) Genome Res , vol.17 , pp. 1520-1528
    • Wray, N.R.1    Goddard, M.E.2    Visscher, P.M.3
  • 39
    • 67349199566 scopus 로고    scopus 로고
    • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
    • Barrett, J.C., Clayton, D.G., Concannon, P., Akolkar, B., Cooper, J.D., Erlich, H.A., Julier, C., et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet 41 (2009), 703–707.
    • (2009) Nat Genet , vol.41 , pp. 703-707
    • Barrett, J.C.1    Clayton, D.G.2    Concannon, P.3    Akolkar, B.4    Cooper, J.D.5    Erlich, H.A.6    Julier, C.7
  • 40
    • 77949772292 scopus 로고    scopus 로고
    • Gene-environment-wide association studies: emerging approaches
    • Thomas, D., Gene-environment-wide association studies: emerging approaches. Nat Rev Genet 11 (2010), 259–272.
    • (2010) Nat Rev Genet , vol.11 , pp. 259-272
    • Thomas, D.1
  • 42
    • 33646347356 scopus 로고    scopus 로고
    • Toll-like receptor signaling in the liver
    • Schwabe, R.F., Seki, E., Brenner, D.A., Toll-like receptor signaling in the liver. Gastroenterology 130 (2006), 1886–1900.
    • (2006) Gastroenterology , vol.130 , pp. 1886-1900
    • Schwabe, R.F.1    Seki, E.2    Brenner, D.A.3
  • 43
    • 0036467392 scopus 로고    scopus 로고
    • Toll-like receptors: key mediators of microbe detection
    • Underhill, D.M., Ozinsky, A., Toll-like receptors: key mediators of microbe detection. Curr Opin Immunol 14 (2002), 103–110.
    • (2002) Curr Opin Immunol , vol.14 , pp. 103-110
    • Underhill, D.M.1    Ozinsky, A.2
  • 44
    • 0038185316 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
    • Paik, Y.H., Schwabe, R.F., Bataller, R., Russo, M.P., Jobin, C., Brenner, D.A., Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology 37 (2003), 1043–1055.
    • (2003) Hepatology , vol.37 , pp. 1043-1055
    • Paik, Y.H.1    Schwabe, R.F.2    Bataller, R.3    Russo, M.P.4    Jobin, C.5    Brenner, D.A.6
  • 46
    • 63349103768 scopus 로고    scopus 로고
    • Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses
    • Guo, J., Loke, J., Zheng, F., Hong, F., Yea, S., Fukata, M., Tarocchi, M., et al. Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses. Hepatology 49 (2009), 960–968.
    • (2009) Hepatology , vol.49 , pp. 960-968
    • Guo, J.1    Loke, J.2    Zheng, F.3    Hong, F.4    Yea, S.5    Fukata, M.6    Tarocchi, M.7
  • 47
    • 77955686233 scopus 로고    scopus 로고
    • Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver
    • Jagavelu, K., Routray, C., Shergill, U., O'Hara, S.P., Faubion, W., Shah, V.H., Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver. Hepatology 52 (2010), 590–601.
    • (2010) Hepatology , vol.52 , pp. 590-601
    • Jagavelu, K.1    Routray, C.2    Shergill, U.3    O'Hara, S.P.4    Faubion, W.5    Shah, V.H.6
  • 49
    • 69949156901 scopus 로고    scopus 로고
    • Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection
    • Li, Y., Chang, M., Abar, O., Garcia, V., Rowland, C., Catanese, J., Ross, D., et al. Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection. J Hepatol 51 (2009), 750–757.
    • (2009) J Hepatol , vol.51 , pp. 750-757
    • Li, Y.1    Chang, M.2    Abar, O.3    Garcia, V.4    Rowland, C.5    Catanese, J.6    Ross, D.7
  • 50
    • 79954481268 scopus 로고    scopus 로고
    • Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis
    • Guo, J., Friedman, S.L., Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis. Fibrogenesis Tissue Repair, 3, 2010, 21.
    • (2010) Fibrogenesis Tissue Repair , vol.3 , pp. 21
    • Guo, J.1    Friedman, S.L.2
  • 51
    • 4344607526 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin
    • Meier, U., Gressner, A.M., Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. Clin Chem 50 (2004), 1511–1525.
    • (2004) Clin Chem , vol.50 , pp. 1511-1525
    • Meier, U.1    Gressner, A.M.2
  • 52
    • 77950600619 scopus 로고    scopus 로고
    • Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans
    • Moreno, M., Chaves, J.F., Sancho-Bru, P., Ramalho, F., Ramalho, L.N., Mansego, M.L., Ivorra, C., et al. Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans. Hepatology 51 (2010), 974–985.
    • (2010) Hepatology , vol.51 , pp. 974-985
    • Moreno, M.1    Chaves, J.F.2    Sancho-Bru, P.3    Ramalho, F.4    Ramalho, L.N.5    Mansego, M.L.6    Ivorra, C.7
  • 53
    • 20844460120 scopus 로고    scopus 로고
    • Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
    • Nagaya, N., Moriya, J., Yasumura, Y., Uematsu, M., Ono, F., Shimizu, W., Ueno, K., et al. Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation 110 (2004), 3674–3679.
    • (2004) Circulation , vol.110 , pp. 3674-3679
    • Nagaya, N.1    Moriya, J.2    Yasumura, Y.3    Uematsu, M.4    Ono, F.5    Shimizu, W.6    Ueno, K.7
  • 55
    • 77956636268 scopus 로고    scopus 로고
    • The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
    • Rotman, Y., Koh, C., Zmuda, J.M., Kleiner, D.E., Liang, T.J., The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology 52 (2010), 894–903.
    • (2010) Hepatology , vol.52 , pp. 894-903
    • Rotman, Y.1    Koh, C.2    Zmuda, J.M.3    Kleiner, D.E.4    Liang, T.J.5
  • 56
    • 77957970113 scopus 로고    scopus 로고
    • A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents
    • Santoro, N., Kursawe, R., D'Adamo, E., Dykas, D.J., Zhang, C.K., Bale, A.E., Cali, A.M., et al. A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. Hepatology 52 (2010), 1281–1290.
    • (2010) Hepatology , vol.52 , pp. 1281-1290
    • Santoro, N.1    Kursawe, R.2    D'Adamo, E.3    Dykas, D.J.4    Zhang, C.K.5    Bale, A.E.6    Cali, A.M.7
  • 57
    • 77957936457 scopus 로고    scopus 로고
    • I148 M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease
    • Valenti, L., Alisi, A., Galmozzi, E., Bartuli, A., Del Menico, B., Alterio, A., Dongiovanni, P., et al. I148 M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease. Hepatology 52 (2010), 1274–1280.
    • (2010) Hepatology , vol.52 , pp. 1274-1280
    • Valenti, L.1    Alisi, A.2    Galmozzi, E.3    Bartuli, A.4    Del Menico, B.5    Alterio, A.6    Dongiovanni, P.7
  • 58
    • 77957941549 scopus 로고    scopus 로고
    • Patatin-like phospholipase domain-containing 3 and the pathogenesis and progression of pediatric nonalcoholic fatty liver disease
    • Browning, J.D., Cohen, J.C., Hobbs, H.H., Patatin-like phospholipase domain-containing 3 and the pathogenesis and progression of pediatric nonalcoholic fatty liver disease. Hepatology 52 (2010), 1189–1192.
    • (2010) Hepatology , vol.52 , pp. 1189-1192
    • Browning, J.D.1    Cohen, J.C.2    Hobbs, H.H.3
  • 59
    • 77949895032 scopus 로고    scopus 로고
    • A sequence variation (I148 M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis
    • He, S., McPhaul, C., Li, J.Z., Garuti, R., Kinch, L., Grishin, N.V., Cohen, J.C., et al. A sequence variation (I148 M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem 285 (2010), 6706–6715.
    • (2010) J Biol Chem , vol.285 , pp. 6706-6715
    • He, S.1    McPhaul, C.2    Li, J.Z.3    Garuti, R.4    Kinch, L.5    Grishin, N.V.6    Cohen, J.C.7
  • 60
    • 85097111186 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on serum lipids
    • Speliotes, E.K., Yerges-Armstrong, L.M., Wu, J., Hernaez, R., Kim, L.J., Palmer, C., Harris, T.B., et al. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on serum lipids. Hepatology, 52, 2010, 450A.
    • (2010) Hepatology , vol.52 , pp. 450A
    • Speliotes, E.K.1    Yerges-Armstrong, L.M.2    Wu, J.3    Hernaez, R.4    Kim, L.J.5    Palmer, C.6    Harris, T.B.7
  • 61
    • 77950607738 scopus 로고    scopus 로고
    • Homozygosity for the patatin-like phospholipase-3/adiponutrin I148 M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
    • Valenti, L., Al-Serri, A., Daly, A.K., Galmozzi, E., Rametta, R., Dongiovanni, P., Nobili, V., et al. Homozygosity for the patatin-like phospholipase-3/adiponutrin I148 M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 51 (2010), 1209–1217.
    • (2010) Hepatology , vol.51 , pp. 1209-1217
    • Valenti, L.1    Al-Serri, A.2    Daly, A.K.3    Galmozzi, E.4    Rametta, R.5    Dongiovanni, P.6    Nobili, V.7
  • 62
    • 56649083495 scopus 로고    scopus 로고
    • Mechanisms of disease progression in nonalcoholic fatty liver disease
    • Jou, J., Choi, S.S., Diehl, A.M., Mechanisms of disease progression in nonalcoholic fatty liver disease. Semin Liver Dis 28 (2008), 370–379.
    • (2008) Semin Liver Dis , vol.28 , pp. 370-379
    • Jou, J.1    Choi, S.S.2    Diehl, A.M.3
  • 63
    • 78751536418 scopus 로고    scopus 로고
    • Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians
    • Stickel, F., Buch, S., Lau, K., Zu Schwabedissen, H.M., Berg, T., Ridinger, M., Rietschel, M., et al. Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology 53 (2011), 86–95.
    • (2011) Hepatology , vol.53 , pp. 86-95
    • Stickel, F.1    Buch, S.2    Lau, K.3    Zu Schwabedissen, H.M.4    Berg, T.5    Ridinger, M.6    Rietschel, M.7
  • 65
    • 85097078554 scopus 로고    scopus 로고
    • Common polymorphism in PNPLA3 gene is associated with steatosis and cirrhosis in alcoholic liver disease
    • Trépo, E., Gustot, T., Degré, D., Lemmers, A., Verset, L., Demetter, P., Ouziel, R., et al. Common polymorphism in PNPLA3 gene is associated with steatosis and cirrhosis in alcoholic liver disease. Hepatology, 52, 2010, 381A.
    • (2010) Hepatology , vol.52 , pp. 381A
    • Trépo, E.1    Gustot, T.2    Degré, D.3    Lemmers, A.4    Verset, L.5    Demetter, P.6    Ouziel, R.7
  • 66
    • 79952305174 scopus 로고    scopus 로고
    • Interferon-Induced Gene Expression Is a Stronger Predictor of Treatment Response than IL28B Genotype in Patients with Hepatitis C. Gastroenterology 2011:in press.
    • Dill MT, Duong FH, Vogt JE, Bibert S, Bochud PY, Terracciano L, Papassotiropoulos A, et al. Interferon-Induced Gene Expression Is a Stronger Predictor of Treatment Response than IL28B Genotype in Patients with Hepatitis C. Gastroenterology 2011:in press.
    • Dill, M.T.1    Duong, F.H.2    Vogt, J.E.3    Bibert, S.4    Bochud, P.Y.5    Terracciano, L.6    Papassotiropoulos, A.7
  • 67
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge, D., Fellay, J., Thompson, A.J., Simon, J.S., Shianna, K.V., Urban, T.J., Heinzen, E.L., et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 461 (2009), 399–401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3    Simon, J.S.4    Shianna, K.V.5    Urban, T.J.6    Heinzen, E.L.7
  • 68
    • 70349548852 scopus 로고    scopus 로고
    • IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
    • Suppiah, V., Moldovan, M., Ahlenstiel, G., Berg, T., Weltman, M., Abate, M.L., Bassendine, M., et al. IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet 41 (2009), 1100–1104.
    • (2009) Nat Genet , vol.41 , pp. 1100-1104
    • Suppiah, V.1    Moldovan, M.2    Ahlenstiel, G.3    Berg, T.4    Weltman, M.5    Abate, M.L.6    Bassendine, M.7
  • 69
    • 77953881002 scopus 로고    scopus 로고
    • Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus
    • e1
    • Thompson, A.J., Muir, A.J., Sulkowski, M.S., Ge, D., Fellay, J., Shianna, K.V., Urban, T., et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology 139 (2010), 120–129 e1.
    • (2010) Gastroenterology , vol.139 , pp. 120-129
    • Thompson, A.J.1    Muir, A.J.2    Sulkowski, M.S.3    Ge, D.4    Fellay, J.5    Shianna, K.V.6    Urban, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.