C-reactive protein level as a predictor of mortality in liver disease patients with bacteremia

Scandinavian Journal of Gastroenterology

Volumn 46, Issue 12, 2011, Pages 1478-1483

  Janum, Sine H ^a   Søvsø, Morten ^a   Gradel, Kim O ^b   Schønheyder, Henrik C ^a   Nielsen, Henrik ^a  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Hepatobiliary clinical; Intensive care medicine

Indexed keywords

C REACTIVE PROTEIN;

ADULT; AGED; ARTICLE; BACTEREMIA; C REACTIVE PROTEIN BLOOD LEVEL; CHILD TURCOTTE PUGH SCORE; CHRONIC LIVER DISEASE; COHORT ANALYSIS; COMORBIDITY; DISEASE ASSOCIATION; FATALITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; RATING SCALE; RESPIRATORY TRACT INFECTION; RETROSPECTIVE STUDY; URINARY TRACT INFECTION;

AGED; BACTEREMIA; C-REACTIVE PROTEIN; CHRONIC DISEASE; FEMALE; HUMANS; LIVER DISEASES; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 80655146173     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2011.615855     Document Type: Article

References (23)

1. Hurlimann J, Thorbecke GJ, Hochwald GM. The liver as the site of C-reactive protein formation. J Exp Med 1966;123: 365-78.
2. Kushner I, Feldmann G. Control of the acute phase response. Demonstration of C-reactive protein synthesis and secretion by hepatocytes during acute inflammation in the rabbit. J Exp Med 1978;148:466-77. (Pubitemid 8392709)
3. Castell JV, Gomez-Lechon MJ, David M, Hirano T, Kishimoto T, Heinrich PC. Recombinant human interleukin-6 (IL-6/BSf-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes. FEBS Letters 1988;232:347-50.
4. Gabay C, Kushner I, Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 1999;340:448-54. (Pubitemid 29084777)
5. Povoa P. C-reactive protein: a valuable marker of sepsis. Intensive Care Med 2002;28:235-43. (Pubitemid 34230643)
6. Simon L, Gauvin F, Amre DK, Saint-Louis P, Lacroix J. Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis 2004;39:206-17. (Pubitemid 38971491)
7. Gradel KO, Thomsen RW, Lundbye-Christensen S, Nielsen H, Schønheyder HC. Baseline C-reactive protein level as a predictor of mortality in bacteraemia patients: a population-based cohort study. Clin Microbiol Infect 2011;17;627-32.
8. Le Moine O, Deviere J, Devaster JM, Crusiaux A, Durand F, Bernuau J, et al. Interleukin-6: an early marker of bacterial infection in decompensated cirrhosis. J Hepatol 1994;20: 819-24. (Pubitemid 24216896)
9. Park WB, Lee KD, Lee CS, Jang HC, Kim HB, Lee HS,et al. Production of C-reactive protein in Eschericia coli-infected patients with liver dysfunction due to liver cirrhosis. Diagn Microbiol Infect Dis 2005;51:227-30. (Pubitemid 40460957)
10. Mackenzie I, Woodhouse J. C-reactive protein concentrations during bacteraemia: a comparison between patients with and without liver dysfunction. Intensive Care Med 2006;32:1344-51. (Pubitemid 44267922)
11. Bota DF, Nuffelen MV, Zakariah AN, Vincent JL. Serum levels of C-reactive protein and procalcitonin in critically ill patients with cirrhosis of the liver. J Lab Clin Med 2005;146: 347-51. (Pubitemid 41712021)
12. Andersen TF, Madsen M, Jørgensen J, Mellemkjær L, Olsen JH. The Danish national hospital register. A valuable source of data for modern health sciences. Dan Med Bull 1999;46:263-8. (Pubitemid 29299976)
13. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis 1987;40: 373-83. (Pubitemid 17055592)
14. Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Brit J Surg 1973;60:646-9.
15. Thulstrup AM, Sørensen HT, Schønheyder HC, Møller JK, Tage-Jensen U. Population-based study of the risk and short-term prognosis for bacteremia in patients with liver cirrhosis. Clin Infect Dis 2000;31:1357-61.
16. Linderoth G, Jepsen P, Schønheyder HC, Johnsen SP, Sørensen HT. Short-term prognosis of community-acquired bacteremia in patients with liver cirrhosis or alcoholism: a population-based cohort study. Alcoholism Clin Exp Res 2006;30:636-41.
17. Chen SY, Tsai CL, Lin CH, Lee CC, Chiang WC, Wang JL, et al. Impact of liver cirrhosis on mortality in patients with community-acquired bacteremia. Diagn Micro-biol Infect Dis 2009;64:124-30.
18. Suffredini AF, Hochstein HD, McMahon FG. Dose-related inflammatory effects of intravenous endotoxin in humans: evaluation of a new clinical lot of Escherichia coli O: 113 endotoxin. J Infect Dis 1999;179:1278-82. (Pubitemid 29196515)
19. Suprin E, Camus C, Gacouin A, Le Tulzo Y, Lavoue S, Feuillu A, et al. Procalcitonin: a valuable indicator of infection in a medical ICU? Intensive Care Med 2000:26:1232-8.
20. Silvestre JPDS, Coelho LMDC, Povoa PMSR. Impact of fulminant hepatic failure in C-reactive protein? J Crit Care 2010;25:657.e7-657.e12.
21. Spahr L, Morard I, Hadengue A, Vadas L, Pugin J. Procal-citonin is not an accurate marker of spontaneous bacterial peritonitis in patients with cirrhosid. Hepatogastroenterology 2001;48:502-5. (Pubitemid 32391600)
22. Leibovici L, Shraga I, Drucker M, Konigsberger H, Samra Z, Pitlik SD. The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. J Intern Med 1998;244:379-86. (Pubitemid 28513125)
23. Vestberg K, Thulstrup AM, Sørensen HT, Ottesen P, Sabroe S, Vilstrup H. Data quality of administratively collected hospital discharge data for liver cirrhosis epidemiology. J Med Syst 1997;21:11-20. (Pubitemid 27229970)