Left atrial size is a potent predictor of mortality in mitral regurgitation due to flail leaflets results from a large international multicenter study

Circulation: Cardiovascular Imaging

Volumn 4, Issue 5, 2011, Pages 473-481

  Rusinaru, Dan ^a   Tribouilloy, Christophe ^a   Grigioni, Francesco ^b   Avierinos, Jean François ^c   Suri, Rakesh M ^e   Barbieri, Andrea ^b   Szymanski, Catherine ^a   Ferlito, Marinella ^b   Michelena, Hector ^e   Tafanelli, Laurence ^c   Bursi, Francesca ^d   Mezghani, Sonia ^a   Branzi, Angelo ^d   Habib, Gilbert ^c   Modena, Maria G ^d   Enriquez Sarano, Maurice ^e  

^a AMIENS UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c University Hospital of Marseille   (France)

^d UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^e MAYO CLINIC   (United States)

Author keywords

Flail leaflets; Left atrium; Mitral valve regurgitation; Prognosis

Indexed keywords

ADULT; AGED; ARTICLE; FEMALE; HEART LEFT ATRIUM; HEART SIZE; HUMAN; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE REGURGITATION; MORTALITY; OVERALL SURVIVAL; PREDICTOR VARIABLE; PRIORITY JOURNAL; SURVIVAL RATE; TREATMENT OUTCOME; CAUSE OF DEATH; CLINICAL TRIAL; COMPARATIVE STUDY; DISEASE COURSE; DOPPLER ECHOCARDIOGRAPHY; ECHOGRAPHY; EUROPE; FOLLOW UP; HEART ATRIUM; HEART ATRIUM FUNCTION; HOSPITALIZATION; METHODOLOGY; MIDDLE AGED; MITRAL VALVE; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; RISK FACTOR; UNITED STATES;

AGED; ATRIAL FUNCTION, LEFT; CAUSE OF DEATH; DISEASE PROGRESSION; ECHOCARDIOGRAPHY, DOPPLER; EUROPE; FEMALE; FOLLOW-UP STUDIES; HEART ATRIA; HUMANS; MALE; MIDDLE AGED; MITRAL VALVE; MITRAL VALVE INSUFFICIENCY; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SURVIVAL RATE; UNITED STATES;

EID: 80555156707     PISSN: 19419651     EISSN: 19420080     Source Type: Journal    
DOI: 10.1161/CIRCIMAGING.110.961011     Document Type: Article

References (30)

1. Enriquez-Sarano M, Avierinos JF, Messika-Zeitoun D, Detaint D, Capps M, Nkomo V, Scott C, Schaff HV, Tajik AJ. Quantitative determinants of the outcome of asymptomatic mitral regurgitation. N Engl J Med. 2005; 352:875-883. (Pubitemid 40300296)
2. Grigioni F, Tribouilloy C, Avierinos JF, Barbieri A, Ferlito M, Trojette F, Tafanelli L, Branzi A, Szymanski C, Habib G, Modena MG, Enriquez- Sarano M. Outcomes in mitral regurgitation due to flail leaflets. J Am Coll Cardiol Img. 2008;1:133-141.
3. Bonow RO, Carabello BA, Chatterjee K, de Leon AC Jr, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O'Gara PT, O'Rourke RA, Otto CM, Shah PM, Shanewise JS, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Page RL, Riegel B. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines developed in collaboration with the Society of Cardiovascular Anesthesiologists endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol. 2006;48:e1-e148.
4. Vahanian A, Baumgartner H, Bax J, Butchart E, Dion R, Filippatos G, Flachskampf F, Hall R, Iung B, Kasprzak J, Nataf P, Tornos P, Torracca L, Wenink A. Guidelines on the management of valvular heart disease: the Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology. Eur Heart J. 2007;28:230-268. (Pubitemid 46276943)
5. Tribouilloy CM, Enriquez-Sarano M, Schaff HV, Orszulak TA, Bailey KR, Tajik AJ, Frye RL. Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation: rationale for optimizing surgical indications. Circulation. 1999;99:400-405. (Pubitemid 29051266)
6. Enriquez-Sarano M, Tajik AJ, Schaff HV, Orszulak TA, Bailey KR, Frye RL. Echocardiographic prediction of survival after surgical correction of organic mitral regurgitation. Circulation. 1994;90:830-837. (Pubitemid 24242752)
7. Tribouilloy C, Grigioni F, Avierinos JF, Barbieri A, Rusinaru D, Szymanski C, Ferlito M, Tafanelli L, Bursi F, Trojette F, Branzi A, Habib G, Modena MG, Enriquez-Sarano M. MIDA Investigators. Survival implication of left ventricular end-systolic diameter in mitral regurgitation due to flail leaflets a long-term follow-up multicenter study. J Am Coll Cardiol 2009;54:1961-1968.
8. Kennedy JW, Yarnall SR, Murray JA, Figley MM. Quantitative angiography, IV: relationships of left atrial and ventricular pressure and volume in mitral valve disease. Circulation. 1970;41:817-824.
9. Corin W, Murakami T, Monrad E, Hess O, Krayenbuehl H. Left ventricular passive diastolic properties in chronic mitral regurgitation. Circulation. 1991;83:797-807.
10. Reed D, Abbott RD, Smucker ML, Kaul S. Prediction of outcome after mitral valve replacement in patients with symptomatic chronic mitral regurgitation. The importance of left atrial size. Circulation. 1991;84: 23-34.
11. Douglas PS. The left atrium: a biomarker of chronic diastolic dysfunction and cardiovascular disease risk. J Am Coll Cardiol. 2003;42:1206-1207. (Pubitemid 37188342)
12. Gardin JM, McClelland R, Kitzman D, Lima JA, Bommer W, Klopfenstein HS, Wong ND, Smith VE, Gottdiener J. M-mode echocardiographic predictors of six- to seven-year incidence of coronary heart disease, stroke, congestive heart failure, and mortality in an elderly cohort (the Cardiovascular Health Study). Am J Cardiol. 2001;87:1051-1057. (Pubitemid 32710318)
13. Benjamin EJ, D'Agostino RB, Belanger AJ, Wolf PA, Levy D. Left atrial size and the risk of stroke and death: the Framingham Heart Study. Circulation. 1995;92:835-841.
14. Laukkanen JA, Kurl S, Eränen J, Huttunen M, Salonen JT. Left atrium size and the risk of cardiovascular death in middle-aged men. Arch Intern Med. 2005;165:1788-1793. (Pubitemid 41138969)
15. Takemoto Y, Barnes ME, Seward JB, Lester SJ, Appleton CA, Gersh BJ, Bailey KR, Tsang TS. Usefulness of left atrial volume in predicting first congestive heart failure in patients-65 years of age with well-preserved left ventricular systolic function. Am J Cardiol. 2005;96:832-836. (Pubitemid 41317661)
16. Vaziri SM, Larson MG, Benjamin EJ, Levy D. Echocardiographic predictors of nonrheumatic atrial fibrillation: the Framingham Heart Study. Circulation. 1994;89:724-730. (Pubitemid 24056200)
17. Rossi A, Cicoira M, Zanolla L, Sandrini R, Golia G, Zardini P, Enriquez- Sarano M. Determinants and prognostic value of left atrial volume in patients with dilated cardiomyopathy. J Am Coll Cardiol. 2002;40: 1425-1430. (Pubitemid 35192867)
18. Moller JE, Hillis GS, Oh JK, Seward JB, Reeder GS, Wright RS, Park SW, Bailey KR, Pellikka PA. Left atrial volume: a powerful predictor of survival after acute myocardial infarction. Circulation. 2003;107: 2207-2212. (Pubitemid 36547214)
19. Grigioni F, Avierinos JF, Ling LH, Scott CG, Bailey KR, Tajik AJ, Frye RL, Enriquez-Sarano M. Atrial fibrillation complicating the course of degenerative mitral regurgitation. Determinants and long-term outcome. J Am Coll Cardiol. 2002;40:84-92. (Pubitemid 34701381)
20. Kernis SJ, Nkomo VT, Messika-Zeitoun D, Gersh BJ, Sundt TM III, Ballman KV, Scott CG, Schaff HV, Enriquez-Sarano M. Atrial fibrillation after surgical correction of mitral regurgitation in sinus rhythm: incidence, outcome, and determinants. Circulation. 2004;110:2320-2325. (Pubitemid 39407333)
21. Messika-Zeitoun D, Bellamy M, Avierinos JF, Breen J, Eusemann C, Rossi A, Behrenbeck T, Scott C, Tajik JA, Enriquez-Sarano M. Left atrial remodelling in mitral regurgitation: methodologic approach, physiological determinants, and outcome implications: a prospective quantitative Doppler-echocardiographic and electron beam-computed tomographic study. Eur Heart J. 2007;28:1773-1781. (Pubitemid 47227098)
22. Le Tourneau T, Messika-Zeitoun D, Russo A, Detaint D, Topilsky Y, Mahoney DW, Suri R, Enriquez-Sarano M. Impact of left atrial volume on clinical outcome in organic mitral regurgitation. J Am Coll Cardiol. 2010;56:570-578.
23. Khankirawatana B, Khankirawatana S, Porter T. How should left atrial size be reported? Comparative assessment with use of multiple echocardiographic methods. Am Heart J. 2004;147:369-374. (Pubitemid 38176840)
24. Tsang TS, Abhayaratna WP, Barnes ME Miyasaka Y, Gersh BJ, Bailey KR, Cha SS, Seward JB. Prediction of cardiovascular outcomes with left atrial size: is volume superior to area or diameter? J Am Coll Cardiol. 2006;47:1018-1023.
25. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-383. (Pubitemid 17055592)
26. Sahn D, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation. 1978;58:1072-1083. (Pubitemid 9091990)
27. Ling LH, Enriquez-Sarano M, Seward JB, Tajik AJ, Schaff HV, Bailey KR, Frye RL. Clinical outcome of mitral regurgitation due to flail leaflet. N Engl J Med. 1996;335:1417-1423. (Pubitemid 26382502)
28. Tsang TS, Barnes ME, Gersh BJ, Bailey KR, Seward JB. Left atrial volume as a morphophysiologic expression of left ventricular diastolic dysfunction and relation to cardiovascular risk burden. Am J Cardiol. 2002;90:1284-1289. (Pubitemid 35449471)
29. Appleton CP, Galloway JM, Gonzalez MS, Gaballa M, Basnight MA. Estimation of left ventricular filling pressures using two-dimensional and Doppler echocardiography in adult patients with cardiac disease: additional value of analyzing left atrial size, left atrial ejection fraction and the difference in duration of pulmonary venous and mitral flow velocity at atrial contraction. J Am Coll Cardiol. 1993;22:1972-1982. (Pubitemid 23359661)
30. Rosenhek R, Rader F, Klaar U, Gabriel H, Krejc M, Kalbeck D, Schemper M, Maurer G, Baumgartner H. Outcome of watchful waiting in asymptomatic severe mitral regurgitation. Circulation. 2006;113: 2238-2244.