Subconjunctival bevacizumab for corneal neovascularization secondary to topical anesthetic abuse

Cutaneous and Ocular Toxicology

Volumn 30, Issue 4, 2011, Pages 320-322

  Georgakopoulos, Constantine D ^a   Vasilakis, Panagiotis ^a   Makri, Olga E ^a   Beredima, Eleni ^a   Pharmakakis, Nikolaos ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

Bevacizumab; Corneal neovascularization; Subconjunctival injection; Tetracaine abuse

Indexed keywords

ANTIBIOTIC AGENT; BEVACIZUMAB; TETRACAINE;

ADULT; ARTICLE; CASE REPORT; CLINICAL EXAMINATION; CLINICAL FEATURE; CORNEA NEOVASCULARIZATION; DRUG EFFICACY; DRUG RESPONSE; DRUG TOLERABILITY; HUMAN; MALE; RELAPSE; SLIT LAMP; TOPICAL ANESTHESIA; VISUAL ACUITY;

ANESTHETICS, LOCAL; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; CORNEAL NEOVASCULARIZATION; HUMANS; INJECTIONS, INTRAOCULAR; KERATITIS; MALE; MIDDLE AGED; OPHTHALMIC SOLUTIONS; TETRACAINE; TREATMENT OUTCOME;

EID: 80455168331     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.3109/15569527.2011.573834     Document Type: Article

References (11)

1. Chen HT, Chen KH, Hsu WM. Toxic keratopathy associated with abuse of low-dose anesthetic: A case report. Cornea 2004;23: 527-529.
2. Rosenwasser GO. Complications of topical ocular anesthetics. Int Ophthalmol Clin 1989;29:153-158. (Pubitemid 19211176)
3. Klebe S, Coster DJ, Williams KA. Rejection and acceptance of corneal allografts. Curr Opin Organ Transplant 2009;14:4-9.
4. Koenig Y, Bock F, Horn F, Kruse F, Straub K, Cursiefen C. Shortand long-term safety profile and efficacy of topical bevacizumab (Avastin) eye drops against corneal neovascularization. Graefes Arch Clin Exp Ophthalmol 2009;247:1375-1382.
5. Varga JH, Rubinfeld RS, Wolf TC, Stutzman RD, Peele KA, Clifford WS et al. Topical anesthetic abuse ring keratitis: Report of four cases. Cornea 1997;16:424-429. (Pubitemid 27282181)
6. Zagelbaum BM, Tostanoski JR, Hochman MA, Hersh PS. Topical lidocaine and proparacaine abuse. Am J Emerg Med 1994;12: 96-97. (Pubitemid 24055939)
7. Rosenwasser GO, Holland S, Pflugfelder SC, Lugo M, Heidemann DG, Culbertson WW et al. Topical anesthetic abuse. Ophthalmology 1990;97:967-972. (Pubitemid 20251122)
8. Philipp W, Speicher L, Humpel C. Expression of vascular endothelial growth factor and its receptors in inflamed and vascularized human corneas. Invest Ophthalmol Vis Sci 2000;41:2514-2522. (Pubitemid 30624378)
9. DeStafeno JJ, Kim T. Topical bevacizumab therapy for corneal neovascularization. Arch Ophthalmol 2007;125:834-836. (Pubitemid 46919748)
10. Carrasco MA. Subconjunctival bevacizumab for corneal neovascularization in herpetic stromal keratitis. Cornea 2008;27: 743-745.
11. Cursiefen C, Hofmann-Rummelt C, Küchle M, Schlötzer-Schrehardt U. Pericyte recruitment in human corneal angiogenesis: An ultrastructural study with clinicopathological correlation. Br J Ophthalmol 2003;87:101-106. (Pubitemid 36071788)