-
1
-
-
77951614830
-
Monoclonal antibodies: Versatile platforms for cancer immunotherapy
-
Weiner LM, Surana R, Wang S. Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat Rev Immunol 2010; 10: 317-327.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 317-327
-
-
Weiner, L.M.1
Surana, R.2
Wang, S.3
-
2
-
-
0036877336
-
Mechanism of action of rituximab
-
Cerny T, Borisch B, Introna M, Johnson P, Rose AL. Mechanism of action of rituximab. Anticancer Drugs 2002; 13: S3-S10.
-
(2002)
Anticancer Drugs
, vol.13
-
-
Cerny, T.1
Borisch, B.2
Introna, M.3
Johnson, P.4
Rose, A.L.5
-
3
-
-
2942567554
-
Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly x 4 schedule
-
Ghielmini M, Schmitz SF, Cogliatti S, et al. Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly x 4 schedule. Blood 2004; 103: 4416-23.
-
(2004)
Blood
, vol.103
, pp. 4416-4423
-
-
Ghielmini, M.1
Schmitz, S.F.2
Cogliatti, S.3
-
4
-
-
78650823247
-
Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): A phase 3, randomised controlled trial
-
Salles G, Seymour JF, Offner F, et al. Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial. Lancet 2010; 377: 42-51.
-
(2010)
Lancet
, vol.377
, pp. 42-51
-
-
Salles, G.1
Seymour, J.F.2
Offner, F.3
-
5
-
-
13244270361
-
CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma
-
Marcus R, Imrie K, Belch A, et al. CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma. Blood 2005; 105: 1417-23.
-
(2005)
Blood
, vol.105
, pp. 1417-1423
-
-
Marcus, R.1
Imrie, K.2
Belch, A.3
-
6
-
-
78650823810
-
Long-term follow-up of patients with follicular lymphoma receiving single-agent rituximab at two different schedules in trial SAKK 35/98
-
Martinelli G, Hsu Schmitz SF, Utiger U et al. Long-term follow-up of patients with follicular lymphoma receiving single-agent rituximab at two different schedules in trial SAKK 35/98. J Clin Oncol 2010; 28: 4480-4484.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4480-4484
-
-
Martinelli, G.1
Hsu, S.S.F.2
Utiger, U.3
-
7
-
-
77957200763
-
Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: A study by the Groupe d'Etudes des Lymphomes de l'Adult
-
Coiffier B, Thieblemont C, Van Den Neste E et al. Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe d'Etudes des Lymphomes de l'Adult., Blood. 2010;116:2040-5.
-
(2010)
Blood
, vol.116
, pp. 2040-2045
-
-
Coiffier, B.1
Thieblemont, C.2
van den Neste, E.3
-
8
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. New Engl J Med 2001; 344: 783-92.
-
(2001)
New Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
9
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. New Engl J Med 2005; 353: 1659-72.
-
(2005)
New Engl J Med
, vol.353
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
-
10
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond EH, Perez EA, Bryant B et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. New Engl J Med 2005; 353: 1673-84.
-
(2005)
New Engl J Med
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, B.3
-
11
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
Bang YJ, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet. 2010;376:687-97.
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
van Cutsem, E.2
Feyereislova, A.3
-
12
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Köhne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med. 2009;360:1408-17.
-
(2009)
N Engl J Med
, vol.360
, pp. 1408-1417
-
-
van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
-
13
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med. 2008;359:1757-65.
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
-
14
-
-
77949891126
-
Dreisbach L Cetuximab and first-line taxane/carboplatin chemotherapy in advanced non-small-cell lung cancer: Results of the randomized multicenter phase III trial BMS099
-
Lynch TJ, Patel T, Dreisbach L Cetuximab and first-line taxane/carboplatin chemotherapy in advanced non-small-cell lung cancer: results of the randomized multicenter phase III trial BMS099. J Clin Oncol. 2010;28:911-7.
-
(2010)
J Clin Oncol
, vol.28
, pp. 911-917
-
-
Lynch, T.J.1
Patel, T.2
-
15
-
-
65349116059
-
Cetuximab plus chemotherapy in patients with advanced non-smallcell lung cancer (FLEX): An open-label randomised phase III trial
-
Pirker R, Pereira JR, Szczesna A, Cetuximab plus chemotherapy in patients with advanced non-smallcell lung cancer (FLEX): an open-label randomised phase III trial Lancet. 2009;373:1525-31.
-
(2009)
Lancet
, vol.373
, pp. 1525-1531
-
-
Pirker, R.1
Pereira, J.R.2
Szczesna, A.3
-
16
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med. 2006;354:567-78.
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
17
-
-
79551520348
-
Treatment-related mortality with bevacizumab in cancer patients. A meta-analysis
-
Ranpura V, Hapani S, Wu S. Treatment-related mortality with bevacizumab in cancer patients. A meta-analysis. JAMA 2011; 305:487-494.
-
(2011)
JAMA
, vol.305
, pp. 487-494
-
-
Ranpura, V.1
Hapani, S.2
Wu, S.3
-
18
-
-
80455165748
-
7 Fragen an Roche-CEO Severin Schwan. Nehmen Sie Roche-Medis?
-
Ausgabe 23. Juli; 3
-
Ambühl I. 7 Fragen an Roche-CEO Severin Schwan. Nehmen Sie Roche-Medis? BLICK 2010; Ausgabe 23. Juli; 3.
-
(2010)
BLICK
-
-
Ambühl, I.1
-
19
-
-
79951966897
-
Addition of bevacizumab to chemotherapy for treatment of solid tumours: Similar results but different conclusions
-
Ocaña A, Amir E, Vera F, Eisenhauer EA, Tannock IF. Addition of bevacizumab to chemotherapy for treatment of solid tumours: similar results but different conclusions. J Clin Oncol 2011; 29: 254-256.
-
(2011)
J Clin Oncol
, vol.29
, pp. 254-256
-
-
Ocaña, A.1
Amir, E.2
Vera, F.3
Eisenhauer, E.A.4
Tannock, I.F.5
-
20
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al: Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
21
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first line therapy in metastatic colo-rectal cancer: A randomized phase III study
-
Saltz L, Clarke S, Diaz-Rubio E et al: Bevacizumab in combination with oxaliplatin-based chemotherapy as first line therapy in metastatic colo-rectal cancer: a randomized phase III study. J Clin Oncol 2008; 26: 2013-2019.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz, L.1
Clarke, S.2
Diaz-Rubio, E.3
-
22
-
-
79551521053
-
Phase III Trial assessing bevacizumab in stages II and III carcinoma of the colon: Results of NSABP protocol C-08
-
Allegra C, Yothers G, O'Connell MJ et al. Phase III Trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08. J Clin Oncol 2010; 29: 11-16.
-
(2010)
J Clin Oncol
, vol.29
, pp. 11-16
-
-
Allegra, C.1
Yothers, G.2
O'Connell, M.J.3
-
23
-
-
36048939391
-
The cost-effectiveness of bevacizumab in the first-line treatment of metastatic colorectal cancer in England and Wales
-
Tappenden P, Jones R, Paisley S, Carroll C. The cost-effectiveness of bevacizumab in the first-line treatment of metastatic colorectal cancer in England and Wales. Eur J Cancer 2007; 43: 2487-2494.
-
(2007)
Eur J Cancer
, vol.43
, pp. 2487-2494
-
-
Tappenden, P.1
Jones, R.2
Paisley, S.3
Carroll, C.4
-
24
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
Miller KD, Chap LI, Homes FSA et al: Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 2005; 23: 792-799.
-
(2005)
J Clin Oncol
, vol.23
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Homes, F.S.A.3
-
25
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007; 357: 2666-76.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
26
-
-
67349270247
-
Bevacizumab inn combination with paclitaxel for HER-2 negative meta static breast cancer: An economic evaluation
-
Dedes KJ, Matter-Walstra K, Schwenkglenks M, Pestalozzi B, Fink D, Brauchli P, Szucs TD. Bevacizumab inn combination with paclitaxel for HER-2 negative meta static breast cancer: an economic evaluation. Eur J Cancer 2009; 45: 1397-1406.
-
(2009)
Eur J Cancer
, vol.45
, pp. 1397-1406
-
-
Dedes, K.J.1
Matter-Walstra, K.2
Schwenkglenks, M.3
Pestalozzi, B.4
Fink, D.5
Brauchli, P.6
Szucs, T.D.7
-
27
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-smallcell lung cancer
-
Sandler A, Gray R, Perry MC, et al: Paclitaxel-carboplatin alone or with bevacizumab for non-smallcell lung cancer. N Engl J Med 2006; 355: 2542-2550.
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
28
-
-
62449124416
-
Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil
-
Reck M, von Pawel J, Zatloukal P, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol. 2009; 27: 1227-34.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1227-1234
-
-
Reck, M.1
von Pawel, J.2
Zatloukal, P.3
-
29
-
-
84873076717
-
-
Egg G. http://de.wikipedia.org/w/index.php?title=Gottfried_Egg&action=edit§ion=1.
-
-
-
Egg, G.1
-
30
-
-
79953874259
-
RIBBON-1: Randomized, doubleblind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growthfactor receptor-2 negative, locally recurrent or metastatic breast cancer
-
Robert NJ, Diéras V, Glaspy J et al: RIBBON-1: randomized, doubleblind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growthfactor receptor-2 negative, locally recurrent or metastatic breast cancer. J Clin Oncol 2011; 29: 1252-60.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1252-1260
-
-
Robert, N.J.1
Diéras, V.2
Glaspy, J.3
-
31
-
-
79953848263
-
Bevacizumab for advanced breast cancer: All tied up with a ribbon?
-
Burstein H. Bevacizumab for advanced breast cancer: all tied up with a ribbon? J Clin Oncol. 2011; 29: 1232-5.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1232-1235
-
-
Burstein, H.1
-
33
-
-
79952091306
-
Modern strategies for hairy cell leukemia
-
Grever MR, Lozanski G. Modern strategies for hairy cell leukemia. J Clin Oncol. 2011; 29: 583-90.
-
(2011)
J Clin Oncol
, vol.29
, pp. 583-590
-
-
Grever, M.R.1
Lozanski, G.2
-
34
-
-
78650625238
-
Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia
-
Preudhomme C, Guilhot J, Nicolini FE, et al. Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia. N Engl J Med. 2010; 363: 2511-21.
-
(2010)
N Engl J Med
, vol.363
, pp. 2511-2521
-
-
Preudhomme, C.1
Guilhot, J.2
Nicolini, F.E.3
-
35
-
-
79955850541
-
Clinical practice guidelines for the treatment of metastatic renal cell carcinoma: Today and tomorrow
-
Molina AM, Motzer RJ. Clinical practice guidelines for the treatment of metastatic renal cell carcinoma: today and tomorrow. Oncologist. 2011; 16 Suppl 2: 45-50.
-
(2011)
Oncologist
, vol.16
, Issue.SUPPL. 2
, pp. 45-50
-
-
Molina, A.M.1
Motzer, R.J.2
-
36
-
-
77954321165
-
Melanoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
ESMO Guidelines Working Group
-
Dummer R, Hauschild A, Guggenheim M, Jost L, Pentheroudakis G; ESMO Guidelines Working Group. Melanoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2010; 21 Suppl 5: v194-v197.
-
(2010)
Ann Oncol
, vol.21
, Issue.SUPPL. 5
-
-
Dummer, R.1
Hauschild, A.2
Guggenheim, M.3
Jost, L.4
Pentheroudakis, G.5
-
37
-
-
77950576363
-
Interferon alpha adjuvant therapy in patients with high-risk melanoma: A systematic review and meta-analysis
-
Mocellin S, Pasquali S, Rossi CR, Nitti D. Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis. J Natl Cancer Inst. 2010; 102: 493-501.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 493-501
-
-
Mocellin, S.1
Pasquali, S.2
Rossi, C.R.3
Nitti, D.4
-
38
-
-
45149117448
-
ESMO Guidelines Working Group. Hematopoietic growth factors: ESMO recommendations for the applications
-
Greil R, Psenak O, Roila F; ESMO Guidelines Working Group. Hematopoietic growth factors: ESMO recommendations for the applications. Ann Oncol. 2008; 19 Suppl 2: ii116-ii118.
-
(2008)
Ann Oncol
, vol.19
, Issue.SUPPL. 2
-
-
Greil, R.1
Psenak, O.2
Roila, F.3
-
39
-
-
77952306234
-
Epoetin alfa in patients with advanced-stage Hodgkin's lymphoma: Results of the randomized placebo-controlled GHSG HD15EPO trial
-
Engert A, Josting A, Haverkamp H, et al. Epoetin alfa in patients with advanced-stage Hodgkin's lymphoma: results of the randomized placebo-controlled GHSG HD15EPO trial. J Clin Oncol 2010; 28: 2239-45.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2239-2245
-
-
Engert, A.1
Josting, A.2
Haverkamp, H.3
-
40
-
-
70049098312
-
Erythropoietin or Darbepoetin for patients with cancer--metaanalysis based on individual patient data
-
CD007303
-
Bohlius J, Schmidlin K, Brillant C, et al. Erythropoietin or Darbepoetin for patients with cancer--metaanalysis based on individual patient data. Cochrane Database Syst Rev. 2009; (3): CD007303.
-
(2009)
Cochrane Database Syst Rev
, Issue.3
-
-
Bohlius, J.1
Schmidlin, K.2
Brillant, C.3
-
41
-
-
65449117261
-
Recombinant human erythropoiesis- stimulating agents and mortality in patients with cancer: A meta-analysis of randomised trials
-
Bohlius J, Schmidlin K, Brillant C et al. Recombinant human erythropoiesis- stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trials. Lancet. 2009; 373: 1532-1542.
-
(2009)
Lancet
, vol.373
, pp. 1532-1542
-
-
Bohlius, J.1
Schmidlin, K.2
Brillant, C.3
|