Naringenin suppresses the production of thymic stromal lymphopoietin through the blockade of RIP2 and caspase-1 signal cascade in mast cells

European Journal of Pharmacology

Volumn 671, Issue 1-3, 2011, Pages 128-132

  Moon, Phil Dong ^a   Choi, In Hwa ^a   Kim, Hyung Min ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Caspase 1; Naringenin; Nuclear factor B; Receptor interacting protein 2; Thymic stromal lymphopoietin

Indexed keywords

CALCIMYCIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; NARINGENIN; PHORBOL 13 ACETATE 12 MYRISTATE; RECEPTOR INTERACTING PROTEIN 2; THYMIC STROMAL LYMPHOPOIETIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MAST CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

CASPASE 1; CELL LINE; CYTOKINES; ENZYME ACTIVATION; FLAVANONES; GENE EXPRESSION REGULATION; HUMANS; MAST CELLS; NF-KAPPA B; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASE 2; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 80455160164     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.09.163     Document Type: Article

References (26)

1. K.A. Boost, S. Hoegl, C. Hofstetter, M. Flondor, K. Stegewerth, I. Platacis, J. Pfeilschifter, H. Muhl, and B. Zwissler Targeting caspase-1 by inhalation-therapy: effects of Ac-YVAD-CHO on IL-1 beta, IL-18 and downstream proinflammatory parameters as detected in rat endotoxaemia Intensive Care Med. 33 2007 863 871 (Pubitemid 46675323)
2. A. Dumortier, A.D. Durham, M. Di Piazza, S. Vauclair, U. Koch, G. Ferrand, I. Ferrero, S. Demehri, L.L. Song, A.G. Farr, W.J. Leonard, R. Kopan, L. Miele, D. Hohl, D. Finke, and F. Radtke Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin PLoS One 5 2010 e9258
3. J.R. Gordon, P.R. Burd, and S.J. Galli Mast cells as a source of multifunctional cytokines Immunol. Today 11 1990 458 464
4. M. Hämäläinen, R. Nieminen, P. Vuorela, M. Heinonen, and E. Moilanen Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages Mediators Inflamm. 2007 2007 45673
5. E.W. Humke, S.K. Shriver, M.A. Starovasnik, W.J. Fairbrother, and V.M. Dixit ICEBERG: a novel inhibitor of interleukin-1beta generation Cell 103 2000 99 111
6. M. Lamkanfi, M. Kalai, X. Saelens, W. Declercq, and P. Vandenabeele Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity J. Biol. Chem. 279 2004 24785 24793 (Pubitemid 38725346)
7. M. Lamkanfi, T.D. Kanneganti, L. Franchi, and G. Núñez Caspase-1 inflammasomes in infection and inflammation J. Leukoc. Biol. 82 2007 220 225 (Pubitemid 47230630)
8. H.C. Lee, M.B. Headley, M. Iseki, K. Ikuta, and S.F. Ziegler Cutting edge: inhibition of NF-kappaB-mediated TSLP expression by retinoid X receptor J. Immunol. 181 2008 5189 5193
9. H.C. Lee, and S.F. Ziegler Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaB Proc. Natl. Acad. Sci. U. S. A. 104 2007 914 919 (Pubitemid 46154711)
10. B. Limasset, C. le Doucen, J.C. Dore, T. Ojasoo, M. Damon, and A. Crastes de Paulet Effects of flavonoids on the release of reactive oxygen species by stimulated human neutrophils. Multivariate analysis of structure-activity relationships (SAR) Biochem. Pharmacol. 46 1993 1257 1271 (Pubitemid 23306748)
11. Y.J. Liu Thymic stromal lymphopoietin: master switch for allergic inflammation J. Exp. Med. 203 2006 269 273
12. P.D. Moon, and H.M. Kim Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-κB pathway in mast cells Cytokine 54 2011 239 243
13. T. Morioka, K. Yamanaka, H. Mori, Y. Omoto, K. Tokime, M. Kakeda, I. Kurokawa, E.C. Gabazza, A. Tsubura, Y. Yasutomi, and H. Mizutani IL-4/IL-13 antagonist DNA vaccination successfully suppresses Th2 type chronic dermatitis Br. J. Dermatol. 160 2009 1172 1179
14. E.E. Mulvihill, and M.W. Huff Antiatherogenic properties of flavonoids: implications for cardiovascular health Can. J. Cardiol. 26 Suppl. A 2010 17A 21A
15. M. Oiwa, T. Satoh, M. Watanabe, H. Niwa, H. Hirai, M. Nakamura, and H. Yokozeki CRTH2-dependent, STAT6-independent induction of cedar pollen dermatitis Clin. Exp. Allergy 38 2008 1357 1366 (Pubitemid 352019661)
16. T. Ozawa, K. Koyama, T. Ando, Y. Ohnuma, K. Hatsushika, T. Ohba, H. Sugiyama, Y. Hamada, H. Ogawa, K. Okumura, and A. Nakao Thymic stromal lymphopoietin secretion of synovial fibroblasts is positively and negatively regulated by Toll-like receptors/nuclear factor-kappaB pathway and interferon-gamma/dexamethasone Mod. Rheumatol. 17 2007 459 463
17. S.G. Plötz, and J. Ring What's new in atopic eczema? Expert Opin. Emerg. Drugs 15 2010 249 267
18. A.J. Reefer, K.E. Hulse, J.A. Lannigan, M.D. Solga, P.W. Wright, L.A. Kelly, J. Patrie, M.D. Chapman, and J.A. Woodfolk Flow cytometry imaging identifies rare T(H)2 cells expressing thymic stromal lymphopoietin receptor in a "proallergic" milieu J. Allergy Clin. Immunol. 126 2010 1049 1058 1058.e1-10
19. C. Schneider, W.D. Döcke, T.M. Zollner, and L. Röse Chronic mouse model of TMA-induced contact hypersensitivity J. Invest. Dermatol. 129 2009 899 907
20. S. Schoonbroodt, S. Legrand-Poels, M. Best-Belpomme, and J. Piette Activation of the NF-kappaB transcription factor in a T-lymphocytic cell line by hypochlorous acid Biochem. J. 321 1997 777 785 (Pubitemid 27084888)
21. L. Shan, N.S. Redhu, A. Saleh, A.J. Halayko, J. Chakir, and A.S. Gounni Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways J. Immunol. 184 2010 7134 7143
22. Y. Shi, J. Dai, H. Liu, R.R. Li, P.L. Sun, Q. Du, L.L. Pang, Z. Chen, and K.S. Yin Naringenin inhibits allergen-induced airway inflammation and airway responsiveness and inhibits NF-kappaB activity in a murine model of asthma Can. J. Physiol. Pharmacol. 87 2009 729 735
23. M. Shulman, M. Cohen, A. Soto-Gutierrez, H. Yagi, H. Wang, J. Goldwasser, C.W. Lee-Parsons, O. Benny-Ratsaby, M.L. Yarmush, and Y. Nahmias Enhancement of naringenin bioavailability by complexation with hydroxypropoyl-β- cyclodextrin PLoS One 6 2011 e18033
24. W.H. Wu, C.O. Park, S.H. Oh, H.J. Kim, Y.S. Kwon, B.G. Bae, J.Y. Noh, and K.H. Lee Thymic stromal lymphopoietin-activated invariant natural killer T cells trigger an innate allergic immune response in atopic dermatitis J. Allergy Clin. Immunol. 126 2010 290 299 299.e1-4
25. Z. Zhang, P. Hener, N. Frossard, S. Kato, D. Metzger, M. Li, and P. Chambon Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma Proc. Natl. Acad. Sci. U. S. A. 106 2009 1536 1541
26. S.F. Ziegler The role of thymic stromal lymphopoietin (TSLP) in allergic disorders Curr. Opin. Immunol. 22 2010 795 799