Myocardial perfusion imaging with 99 mTc - tetrofosmin SPECT in breast cancer patients that received postoperative radiotherapy: A case-control study

Radiation Oncology

Volumn 6, Issue 1, 2011, Pages

  Sioka, Chrissa ^a   Exarchopoulos, Thomas ^a   Tasiou, Ifigenia ^a   Tzima, Eftychia ^a   Fotou, Nikolaos ^a   Capizzello, Antonio ^a   Ragos, Vasilios ^a   Tsekeris, Periklis ^a   Fotopoulos, Andreas ^a  

^a UNIVERSITY HOSPITAL OF IOANNINA   (Greece)

Author keywords

Breast cancer; Myocardium; Radiotherapy; Spect

Indexed keywords

DOXORUBICIN; EPIRUBICIN; TETROFOSMIN TC 99M; ORGANOPHOSPHORUS COMPOUND; RADIOPHARMACEUTICAL AGENT; TECHNETIUM COMPLEX; TECHNETIUM TC 99M 1,2 BIS(BIS(2 ETHOXYETHYL)PHOSPHINO)ETHANE; TECHNETIUM TC 99M 1,2-BIS(BIS(2-ETHOXYETHYL)PHOSPHINO)ETHANE;

ADJUVANT CHEMOTHERAPY; AGED; ARTICLE; BREAST CANCER; CANCER PATIENT; CANCER RADIOTHERAPY; CARDIOTOXICITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MULTIPLE REGRESSION; MYOCARDIAL PERFUSION IMAGING; POSTOPERATIVE CARE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ADULT; BREAST TUMOR; CASE CONTROL STUDY; METHODOLOGY; MIDDLE AGED; PATHOLOGY; POSTOPERATIVE PERIOD; RADIOTHERAPY; RISK FACTOR; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CHEMOTHERAPY, ADJUVANT; FEMALE; HUMANS; MIDDLE AGED; ORGANOPHOSPHORUS COMPOUNDS; ORGANOTECHNETIUM COMPOUNDS; POSTOPERATIVE PERIOD; RADIOPHARMACEUTICALS; RADIOTHERAPY; RISK FACTORS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TREATMENT OUTCOME;

EID: 80455158252     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-6-151     Document Type: Article

References (36)

1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010, 127:2893-2917. 10.1002/ijc.25516, 21351269.
2. Jagsi R, Pierce L. Postmastectomy radiation therapy for patients with locally advanced breast cancer. Semin Radiat Oncol 2009, 19:236-243. 10.1016/j.semradonc.2009.05.009, 19732688.
3. Motwani SB, Goyal S, Moran MS, Chhabra A, Haffty BG. Ductal carcinoma in situ treated with breast-conserving surgery and radiotherapy: A comparison with ECOG study 5194. Cancer 2011, 117:1156-1162. 10.1002/cncr.25623, 21381008.
4. Clarke M, Collins R, Darby S, Davies C, Elphinstone P, Evans E, Godwin J, Gray R, Hicks C, James S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005, 366:2087-2106.
5. Giordano SH, Kuo YF, Freeman JL, Buchholz TA, Hortobagyi GN, Goodwin JS. Risk of cardiac death after adjuvant radiotherapy for breast cancer. J Natl Cancer Inst 2005, 97:419-424. 10.1093/jnci/dji067, 1853253, 15770005.
6. Hurkmans CW, Borger JH, Bos LJ, van der Horst A, Pieters BR, Lebesque JV, Mijnheer BJ. Cardiac and lung complication probabilities after breast cancer irradiation. Radiother Oncol 2000, 55:145-151. 10.1016/S0167-8140(00)00152-3, 10799726.
7. Gyenes G, Fornander T, Carlens P, Rutqvist LE. Morbidity of ischemic heart disease in early breast cancer 15-20 years after adjuvant radiotherapy. Int J Radiat Oncol Biol Phys 1994, 28:1235-1241. 10.1016/0360-3016(94)90500-2, 8175411.
8. Gyenes G, Rutqvist LE, Liedberg A, Fornander T. Long-term cardiac morbidity and mortality in a randomized trial of pre- and postoperative radiation therapy versus surgery alone in primary breast cancer. Radiother Oncol 1998, 48:185-190. 10.1016/S0167-8140(98)00062-0, 9783890.
9. Taylor CW, McGale P, Darby SC. Cardiac risks of breast-cancer radiotherapy: a contemporary view. Clin Oncol (R Coll Radiol) 2006, 18:236-246.
10. Gimelli A, Rossi G, Landi P, Marzullo P, Iervasi G, L'Abbate A, Rovai D. Stress/Rest Myocardial Perfusion Abnormalities by Gated SPECT: Still the Best Predictor of Cardiac Events in Stable Ischemic Heart Disease. J Nucl Med 2009, 50:546-553. 10.2967/jnumed.108.055954, 19289433.
11. Anagnostopoulos C, Harbinson M, Kelion A, Kundley K, Loong CY, Notghi A, Reyes E, Tindale W, Underwood SR. Procedure guidelines for radionuclide myocardial perfusion imaging. Heart 2004, 90(Suppl 1):i1-10. 1876307, 14676223.
12. Hansen CL, Goldstein RA, Akinboboye OO, Berman DS, Botvinick EH, Churchwell KB, Cooke CD, Corbett JR, Cullom SJ, Dahlberg ST, et al. Myocardial perfusion and function: single photon emission computed tomography. J Nucl Cardiol 2007, 14:e39-60. 10.1016/j.nuclcard.2007.09.023, 18022099.
13. Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, Pennell DJ, Rumberger JA, Ryan T, Verani MS. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. J Nucl Cardiol 2002, 9:240-245. 10.1067/mnc.2002.123122, 11986572.
14. Belardinelli R, Cianci G, Gigli M, Mazzanti M, Lacalaprice F. Effects of trimetazidine on myocardial perfusion and left ventricular systolic function in type 2 diabetic patients with ischemic cardiomyopathy. J Cardiovasc Pharmacol 2008, 51:611-615. 10.1097/FJC.0b013e31817bdd66, 18574390.
15. Gyenes G. Radiation-induced ischemic heart disease in breast cancer--a review. Acta Oncol 1998, 37:241-246. 10.1080/028418698429522, 9677094.
16. Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group. Lancet 2000, 355:1757-1770.
17. Beckham WA, Popescu CC, Patenaude VV, Wai ES, Olivotto IA. Is multibeam IMRT better than standard treatment for patients with left-sided breast cancer?. Int J Radiat Oncol Biol Phys 2007, 69:918-924. 10.1016/j.ijrobp.2007.06.060, 17889273.
18. Donovan E, Bleakley N, Denholm E, Evans P, Gothard L, Hanson J, Peckitt C, Reise S, Ross G, Sharp G, et al. Randomised trial of standard 2D radiotherapy (RT) versus intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Radiother Oncol 2007, 82:254-264. 10.1016/j.radonc.2006.12.008, 17224195.
19. Hojris I, Overgaard M, Christensen JJ, Overgaard J. Morbidity and mortality of ischaemic heart disease in high-risk breast-cancer patients after adjuvant postmastectomy systemic treatment with or without radiotherapy: analysis of DBCG 82b and 82 c randomised trials. Radiotherapy Committee of the Danish Breast Cancer Cooperative Group. Lancet 1999, 354:1425-1430. 10.1016/S0140-6736(99)02245-X, 10543669.
20. Gagliardi G, Constine LS, Moiseenko V, Correa C, Pierce LJ, Allen AM, Marks LB. Radiation dose-volume effects in the heart. Int J Radiat Oncol Biol Phys 2010, 76:S77-85. 10.1016/j.ijrobp.2009.04.093, 20171522.
21. Correa CR, Das IJ, Litt HI, Ferrari V, Hwang WT, Solin LJ, Harris EE. Association between tangential beam treatment parameters and cardiac abnormalities after definitive radiation treatment for left sited breast cancer. Int J Radiat Oncol Biol Phys 2008, 72:5098-516.
22. Stewart FA, Hoving S, Russell NS. Vascular Damage as an Underlying Mechanism of Cardiac and Cerebral Toxicity in Irradiated Cancer Patients. Radiat Res 2010, 174:865-869. 10.1667/RR1862.1, 21128810.
23. Gyenes G, Fornander T, Carlens P, Glas U, Rutqvist LE. Detection of radiation-induced myocardial damage by technetium-99m sestamibi scintigraphy. Eur J Nucl Med 1997, 24:286-292.
24. Hardenbergh PH, Munley MT, Bentel GC, Kedem R, Borges-Neto S, Hollis D, Prosnitz LR, Marks LB. Cardiac perfusion changes in patients treated for breast cancer with radiation therapy and doxorubicin: preliminary results. Int J Radiat Oncol Biol Phys 2001, 49:1023-1028. 10.1016/S0360-3016(00)01531-5, 11240243.
25. Lind PA, Pagnanelli R, Marks LB, Borges-Neto S, Hu C, Zhou SM, Light K, Hardenbergh PH. Myocardial perfusion changes in patients irradiated for left-sided breast cancer and correlation with coronary artery distribution. Int J Radiat Oncol Biol Phys 2003, 55:914-920. 10.1016/S0360-3016(02)04156-1, 12605969.
26. Marks LB, Yu X, Prosnitz RG, Zhou SM, Hardenbergh PH, Blazing M, Hollis D, Lind P, Tisch A, Wong TZ, Borges-Neto S. The incidence and functional consequences of RT-associated cardiac perfusion defects. Int J Radiat Oncol Biol Phys 2005, 63:214-223. 10.1016/j.ijrobp.2005.01.029, 16111592.
27. Prosnitz RG, Hubbs JL, Evans ES, Zhou SM, Yu X, Blazing MA, Hollis DR, Tisch A, Wong TZ, Borges-Neto S, et al. Prospective assessment of radiotherapy-associated cardiac toxicity in breast cancer patients: analysis of data 3 to 6 years after treatment. Cancer 2007, 110:1840-1850. 10.1002/cncr.22965, 17763369.
28. Seddon B, Cook A, Gothard L, Salmon E, Latus K, Underwood SR, Yarnold J. Detection of defects in myocardial perfusion imaging in patients with early breast cancer treated with radiotherapy. Radiother Oncol 2002, 64:53-63. 10.1016/S0167-8140(02)00133-0, 12208576.
29. Tzonevska A, Tzvetkov K, Parvanova V, Dimitrova M. 99mTc-MIBI myocardial perfusion scintigraphy for assessment of myocardial damage after radiotherapy in patients with breast cancer. J BUON 2006, 11:505-509.
30. Yu X, Prosnitz RR, Zhou S, Hardenberg PH, Tisch A, Blazing MA, Borges-Neto S, Hollis D, Wong T, Marks LB. Symptomatic cardiac events following radiation therapy for left-sided breast cancer: possible association with radiation therapy-induced changes in regional perfusion. Clin Breast Cancer 2003, 4:193-197.
31. Taylor CW, Bronnum D, Darby SC, Gagliardi G, Hall P, Jensen MB, McGale P, Nisbet A, Ewertz M. Cardiac dose estimates from Danish and Swedish breast cancer radiotherapy during 1977-2001. Radiother Oncol 2011, 100:176-183. 10.1016/j.radonc.2011.01.020, 3168733, 21376412.
32. Doyle JJ, Neugut AI, Jacobson JS, Wang J, McBride R, Grann A, Grann VR, Hershman D. Radiation therapy, cardiac risk factors, and cardiac toxicity in early-stage breast cancer patients. Int J Radiat Oncol Biol Phys 2007, 68:82-93. 10.1016/j.ijrobp.2006.12.019, 17336464.
33. I HL, Sand NP, Andersen J, Rehling M, Overgaard M. Myocardial perfusion imaging in breast cancer patients treated with or without post-mastectomy radiotherapy. Radiother Oncol 2000, 55:163-172. 10.1016/S0167-8140(00)00170-5, 10799728.
34. Harris EE, Correa C, Hwang WT, Liao J, Litt HI, Ferrari VA, Solin LJ. Late cardiac mortality and morbidity in early-stage breast cancer patients after breast-conservation treatment. J Clin Oncol 2006, 24:4100-4106. 10.1200/JCO.2005.05.1037, 16908933.
35. Goethals I, Dierckx R, De Meerleer G, De Sutter J, De Winter O, De Neve W, Van de Wiele C. The role of nuclear medicine in the prediction and detection of radiation-associated normal pulmonary and cardiac damage. J Nucl Med 2003, 44:1531-1539.
36. Goethals I, De Winter O, De Bondt P, De Sutter J, Dierckx R, Van De Wiele C. The clinical value of nuclear medicine in the assessment of irradiation-induced and anthracycline-associated cardiac damage. Ann Oncol 2002, 13:1331-1339. 10.1093/annonc/mdf318, 12196357.