메뉴 건너뛰기




Volumn 16, Issue 4, 2011, Pages

Development of a compact terahertz time-domain spectrometer for the measurement of the optical properties of biological tissues

Author keywords

Compact; Optical properties; Skin; Terahertz; Terahertz time domain spectroscopy; THz

Indexed keywords

ABSORPTION COEFFICIENTS; COMPACT; EX-VIVO; HEALTH ASSESSMENTS; INDEX OF REFRACTION; N VALUE; OPTICAL PROPERTIES OF BIOLOGICAL TISSUES; SKIN BURN; SKIN SAMPLES; TERA HERTZ; TERAHERTZ SPECTROMETER; TERAHERTZ TIME DOMAIN SPECTROSCOPY; THZ; THZ TIME DOMAIN SPECTROSCOPY; THZ-TDS; TIME-DOMAIN SPECTROMETER;

EID: 80455141640     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3570648     Document Type: Article
Times cited : (103)

References (68)
  • 1
    • 0036769849 scopus 로고    scopus 로고
    • Materials for terahertz science and technology
    • B. Ferguson and X.-C. Zhang, "Materials for terahertz science and technology," Nat Mater 1(1), 26-33 (2002).
    • (2002) Nat Mater , vol.1 , Issue.1 , pp. 26-33
    • Ferguson, B.1    Zhang, X.-C.2
  • 3
    • 41149146731 scopus 로고    scopus 로고
    • Terahertz spectroscopy and imaging for defense and security applications
    • H.-B. Liu, H. Zhong, N. Karpowicz, Y. Chen, and X.-C. Zhang, "Terahertz spectroscopy and imaging for defense and security applications," Proc. IEEE 95(8), 1514-1527 (2007).
    • (2007) Proc. IEEE , vol.95 , Issue.8 , pp. 1514-1527
    • Liu, H.-B.1    Zhong, H.2    Karpowicz, N.3    Chen, Y.4    Zhang, X.-C.5
  • 5
    • 34548424447 scopus 로고    scopus 로고
    • Terahertz quantum-cascade lasers
    • B. S. Williams, "Terahertz quantum-cascade lasers," Nature Photon. 1(9), 517-525 (2007).
    • (2007) Nature Photon. , vol.1 , Issue.9 , pp. 517-525
    • Williams, B.S.1
  • 7
    • 0034499037 scopus 로고    scopus 로고
    • Spectroscopy and dynamics of mixtures of water with acetone, acetonitrile, and methanol
    • D. Venables and C. Schmuttenmaer, "Spectroscopy and dynamics of mixtures of water with acetone, acetonitrile, and methanol," J. Chem. Phys. 113(24), 11222-11236 (2000).
    • (2000) J. Chem. Phys. , vol.113 , Issue.24 , pp. 11222-11236
    • Venables, D.1    Schmuttenmaer, C.2
  • 8
    • 0034702608 scopus 로고    scopus 로고
    • Structure and dynamics of nonaqueous mixtures of dipolar liquids. I. Infrared and far-infrared spectroscopy
    • D. S. Venables, A. Chiu, and C. A. Schmuttenmaer, "Structure and dynamics of nonaqueous mixtures of dipolar liquids. I. Infrared and far-infrared spectroscopy," J. Chem. Phys. 13(8), 3243-3248 (2000).
    • (2000) J. Chem. Phys. , vol.13 , Issue.8 , pp. 3243-3248
    • Venables, D.S.1    Chiu, A.2    Schmuttenmaer, C.A.3
  • 10
    • 33645210306 scopus 로고    scopus 로고
    • Simulating the response of terahertz radiation to basal cell carcinoma using ex vivo spectroscopy measurements
    • E. Pickwell, A. J. Fitzgerald, B. E. Cole, P. F. Taday, R. J. Pye, T. Ha, M. Pepper, and V. P. Wallace, "Simulating the response of terahertz radiation to basal cell carcinoma using ex vivo spectroscopy measurements," J. Biomed. Opt. 10(6), 064021 (2005).
    • (2005) J. Biomed. Opt. , vol.10 , Issue.6 , pp. 064021
    • Pickwell, E.1    Fitzgerald, A.J.2    Cole, B.E.3    Taday, P.F.4    Pye, R.J.5    Ha, T.6    Pepper, M.7    Wallace, V.P.8
  • 11
    • 68349104945 scopus 로고    scopus 로고
    • Terahertz pulsed imaging - A potential medical imaging modality?
    • E. Pickwell-MacPherson and V. P. Wallace, "Terahertz pulsed imaging - a potential medical imaging modality?," Photodiagnosis Photodyn. Ther. 6(2), 128-134 (2009).
    • (2009) Photodiagnosis Photodyn. Ther. , vol.6 , Issue.2 , pp. 128-134
    • Pickwell-MacPherson, E.1    Wallace, V.P.2
  • 15
    • 47649117497 scopus 로고    scopus 로고
    • The impact of hydration changes in fresh bio-tissue on THz spectroscopic measurements
    • G. Png, J. Choi, B. Ng, S. Mickan, D. Abbott, and X. Zhang, "The impact of hydration changes in fresh bio-tissue on THz spectroscopic measurements," Phys. Med. Biol. 53(13), 3501 (2008).
    • (2008) Phys. Med. Biol. , vol.53 , Issue.13 , pp. 3501
    • Png, G.1    Choi, J.2    Ng, B.3    Mickan, S.4    Abbott, D.5    Zhang, X.6
  • 22
    • 34547512209 scopus 로고    scopus 로고
    • Imaging with terahertz radiation
    • W. L. Chan, J. Deibel, and D. M. Mittleman, "Imaging with terahertz radiation," Rep. Prog. Phys. 70(8), 1325-1379 (2007).
    • (2007) Rep. Prog. Phys. , vol.70 , Issue.8 , pp. 1325-1379
    • Chan, W.L.1    Deibel, J.2    Mittleman, D.M.3
  • 23
    • 58449083523 scopus 로고    scopus 로고
    • Terahertz imaging: A report on progress
    • R. Bogue, "Terahertz imaging: a report on progress," Sens. Rev. 29(1), 6-12 (2009).
    • (2009) Sens. Rev. , vol.29 , Issue.1 , pp. 6-12
    • Bogue, R.1
  • 24
    • 33846068784 scopus 로고    scopus 로고
    • Terahertz-wave sources and imaging applications
    • A. Dobroiu, C. Otani, and K. Kawase, "Terahertz-wave sources and imaging applications," Meas. Sci. Technol. 17(11), R161-R174 (2006).
    • (2006) Meas. Sci. Technol. , vol.17 , Issue.11
    • Dobroiu, A.1    Otani, C.2    Kawase, K.3
  • 25
    • 30344446932 scopus 로고    scopus 로고
    • Detection and identification of explosive RDX by THz diffuse reflection spectroscopy
    • H.-B. Liu, Y. Chen, G. J. Bastiaans, and X. C. Zhang, "Detection and identification of explosive RDX by THz diffuse reflection spectroscopy," Opt. Express 14(1), 415-423 (2006).
    • (2006) Opt. Express , vol.14 , Issue.1 , pp. 415-423
    • Liu, H.-B.1    Chen, Y.2    Bastiaans, G.J.3    Zhang, X.C.4
  • 27
    • 1842615258 scopus 로고    scopus 로고
    • Non-destructive terahertz imaging of illicit drugs using spectral fingerprints
    • K. Kawase, Y. Ogawa, Y. Watanabe, and H. Inoue, "Non-destructive terahertz imaging of illicit drugs using spectral fingerprints," Opt. Express 11(20), 2549-2554 (2003).
    • (2003) Opt. Express , vol.11 , Issue.20 , pp. 2549-2554
    • Kawase, K.1    Ogawa, Y.2    Watanabe, Y.3    Inoue, H.4
  • 28
    • 33748552723 scopus 로고    scopus 로고
    • Far-infrared dielectric properties of polar liquids probed by femtosecond terahertz pulse spectroscopy
    • J. T. Kindt and C. A. Schmuttenmaer, "Far-infrared dielectric properties of polar liquids probed by femtosecond terahertz pulse spectroscopy," J. Phys. Chem. 100(24), 10373-10379 (1996).
    • (1996) J. Phys. Chem. , vol.100 , Issue.24 , pp. 10373-10379
    • Kindt, J.T.1    Schmuttenmaer, C.A.2
  • 29
    • 0032027902 scopus 로고    scopus 로고
    • Far-infrared spectra and associated dynamics in acetonitrile-water mixtures measured with femtosecond THz pulse spectroscopy
    • D. S. Venables and C. A. Schmuttenmaer, "Far-infrared spectra and associated dynamics in acetonitrile-water mixtures measured with femtosecond THz pulse spectroscopy," J. Chem. Phys. 108(12), 4935-4944 (1998).
    • (1998) J. Chem. Phys. , vol.108 , Issue.12 , pp. 4935-4944
    • Venables, D.S.1    Schmuttenmaer, C.A.2
  • 30
    • 46149112797 scopus 로고    scopus 로고
    • Characterization of aqueous alcohol solutions in bottles with THz reflection spectroscopy
    • P. U. Jepsen, J. K. Jensen, and U. Moller, "Characterization of aqueous alcohol solutions in bottles with THz reflection spectroscopy," Opt. Express 16(13), 9318-9331 (2008).
    • (2008) Opt. Express , vol.16 , Issue.13 , pp. 9318-9331
    • Jepsen, P.U.1    Jensen, J.K.2    Moller, U.3
  • 31
    • 80455139586 scopus 로고    scopus 로고
    • Broadband THz time-domain spectroscopy of biomolecules
    • Albert-Ludwigs-Universitat: Freiburg im Bresigau
    • B. M. Fischer, "Broadband THz time-domain spectroscopy of biomolecules," in Mathematics and Physics, p. 246, Albert-Ludwigs- Universitat: Freiburg im Bresigau (2005).
    • (2005) Mathematics and Physics , pp. 246
    • Fischer, B.M.1
  • 32
    • 35948956355 scopus 로고    scopus 로고
    • Investigation of aqueous alcohol and sugar solutions with reflection terahertz time-domain spectroscopy
    • P. U. Jepsen, U. Moller, and H. Merbold, "Investigation of aqueous alcohol and sugar solutions with reflection terahertz time-domain spectroscopy," Opt. Express 15(22), 14717-14737 (2007).
    • (2007) Opt. Express , vol.15 , Issue.22 , pp. 14717-14737
    • Jepsen, P.U.1    Moller, U.2    Merbold, H.3
  • 33
    • 77957667932 scopus 로고    scopus 로고
    • Dielectric properties of water in butter and water-AOT-heptane systems measured using terahertz time-domain spectroscopy
    • U. Moller, J. R. Folkenberg, and P. U. Jepsen, "Dielectric properties of water in butter and water-AOT-heptane systems measured using terahertz time-domain spectroscopy," Appl. Spectrosc. 64(9), 1028-1036 (2010).
    • (2010) Appl. Spectrosc. , vol.64 , Issue.9 , pp. 1028-1036
    • Moller, U.1    Folkenberg, J.R.2    Jepsen, P.U.3
  • 34
    • 0038373344 scopus 로고    scopus 로고
    • THz-spectroscopy of biological molecules
    • T. Globus, "THz-Spectroscopy of biological molecules," J. Biol. Phys. 29(2), 89-100 (2003).
    • (2003) J. Biol. Phys. , vol.29 , Issue.2 , pp. 89-100
    • Globus, T.1
  • 35
    • 0040603414 scopus 로고
    • Computer simulation of hydrogen-bonding liquids
    • B. M. Ladanyi and M. S. Skaf, "Computer simulation of hydrogen-bonding liquids," Annu. Rev. Phys. Chem. 44(1), 335-368 (1993).
    • (1993) Annu. Rev. Phys. Chem. , vol.44 , Issue.1 , pp. 335-368
    • Ladanyi, B.M.1    Skaf, M.S.2
  • 36
    • 1542375172 scopus 로고    scopus 로고
    • Hydration dynamics near a model protein surface
    • D. Russo, G. Hura, and T. Head-Gordon, "Hydration dynamics near a model protein surface," Biophys. J. 86(3), 1852-1862 (2004).
    • (2004) Biophys. J. , vol.86 , Issue.3 , pp. 1852-1862
    • Russo, D.1    Hura, G.2    Head-Gordon, T.3
  • 37
    • 53549119134 scopus 로고    scopus 로고
    • Origin of the fast relaxation component of water and heavy water revealed by terahertz time-domain attenuated total reflection spectroscopy
    • H. Yada, M. Nagai, and K. Tanaka, "Origin of the fast relaxation component of water and heavy water revealed by terahertz time-domain attenuated total reflection spectroscopy," Chem. Phys. Lett. 464(4-6), 166-170 (2008).
    • (2008) Chem. Phys. Lett. , vol.464 , Issue.4-6 , pp. 166-170
    • Yada, H.1    Nagai, M.2    Tanaka, K.3
  • 38
    • 0037180421 scopus 로고    scopus 로고
    • Ultrafast surface hydration dynamics and expression of protein functionality: Alpha-chymotrypsin
    • S. K. Pal, J. Peon, and A. H. Zewail, "Ultrafast surface hydration dynamics and expression of protein functionality: alpha-Chymotrypsin," Proc. Natl. Acad. Sci. U.S.A. 99(24), 15297-15302 (2002).
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , Issue.24 , pp. 15297-15302
    • Pal, S.K.1    Peon, J.2    Zewail, A.H.3
  • 39
    • 0037133342 scopus 로고    scopus 로고
    • Biological water at the protein surface: Dynamical solvation probed directly with femtosecond resolution
    • S. K. Pal, J. Peon, and A. H. Zewail, "Biological water at the protein surface: dynamical solvation probed directly with femtosecond resolution," Proc. Natl. Acad. Sci. U.S.A. 99(4), 1763-1768 (2002).
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , Issue.4 , pp. 1763-1768
    • Pal, S.K.1    Peon, J.2    Zewail, A.H.3
  • 40
    • 2342527858 scopus 로고    scopus 로고
    • Dynamics of water in biological recognition
    • S. K. Pal and A. H. Zewail, "Dynamics of water in biological recognition," Chem. Rev. 104(4), 2099-2123 (2004).
    • (2004) Chem. Rev. , vol.104 , Issue.4 , pp. 2099-2123
    • Pal, S.K.1    Zewail, A.H.2
  • 41
    • 0345133351 scopus 로고    scopus 로고
    • Site- and sequence-selective ultrafast hydration of DNA
    • S. K. Pal, L. Zhao, T. Xia, and A. H. Zewail, "Site- and sequence-selective ultrafast hydration of DNA," Proc. Natl. Acad. Sci. U.S.A. 100(24), 13746-13751(2003).
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , Issue.24 , pp. 13746-13751
    • Pal, S.K.1    Zhao, L.2    Xia, T.3    Zewail, A.H.4
  • 42
    • 0037816372 scopus 로고    scopus 로고
    • Water at DNA surfaces: Ultrafast dynamics in minor groove recognition
    • S. K. Pal, L. Zhao, and A. H. Zewail, "Water at DNA surfaces: ultrafast dynamics in minor groove recognition," Proc. Natl. Acad. Sci. U.S.A. 100(14), 8113-8118 (2003).
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , Issue.14 , pp. 8113-8118
    • Pal, S.K.1    Zhao, L.2    Zewail, A.H.3
  • 43
    • 0042910364 scopus 로고    scopus 로고
    • Farinfrared vibrational spectra of all-trans, 9-cis and 13-cis retinal measured by THz time-domain spectroscopy
    • M. Walther, B. Fischer, M. Schall, H. Helm, and P. U. Jepsen, "Farinfrared vibrational spectra of all-trans, 9-cis and 13-cis retinal measured by THz time-domain spectroscopy," Chem. Phys. Lett. 332(3-4), 389-395 (2000).
    • (2000) Chem. Phys. Lett. , vol.332 , Issue.3-4 , pp. 389-395
    • Walther, M.1    Fischer, B.2    Schall, M.3    Helm, H.4    Jepsen, P.U.5
  • 44
    • 0036041539 scopus 로고    scopus 로고
    • Excited-state lifetimes of far-infrared collective modes in proteins
    • A. Xie, "Excited-State Lifetimes of Far-Infrared Collective Modes in Proteins," J. Biol. Phys. 28, 147-154 (2002).
    • (2002) J. Biol. Phys. , vol.28 , pp. 147-154
    • Xie, A.1
  • 48
    • 12344296484 scopus 로고    scopus 로고
    • Dynamic range in terahertz timedomain transmission and reflection spectroscopy
    • P. U. Jepsen and B. M. Fischer, "Dynamic range in terahertz timedomain transmission and reflection spectroscopy," Opt. Lett. 30(1), 29-31 (2005).
    • (2005) Opt. Lett. , vol.30 , Issue.1 , pp. 29-31
    • Jepsen, P.U.1    Fischer, B.M.2
  • 49
    • 84975564504 scopus 로고
    • Radiation patterns from lens-coupled terahertz antennas
    • P. U. Jepsen and S. R. Keiding, "Radiation patterns from lens-coupled terahertz antennas," Opt. Lett. 20(8), 807-809 (1995).
    • (1995) Opt. Lett. , vol.20 , Issue.8 , pp. 807-809
    • Jepsen, P.U.1    Keiding, S.R.2
  • 50
    • 65149088778 scopus 로고    scopus 로고
    • Optical property of human skin
    • L. X. Cundin, G. J. Wilmink, and W. P. Roach, "Optical property of human skin," Proc. SPIE 7175, 717517 (2009).
    • (2009) Proc. SPIE , vol.7175 , pp. 717517
    • Cundin, L.X.1    Wilmink, G.J.2    Roach, W.P.3
  • 54
    • 33747593320 scopus 로고    scopus 로고
    • Biomedical applications of terahertz technology
    • E. Pickwell and V. P. Wallace, "Biomedical applications of terahertz technology," J. Phys. D: Appl. Phys. 39, R301-R310 (2006).
    • (2006) J. Phys. D: Appl. Phys. , vol.39
    • Pickwell, E.1    Wallace, V.P.2
  • 57
    • 77950365626 scopus 로고    scopus 로고
    • Effects of formalin fixing on the terahertz properties of biological tissues
    • Y. Sun, B. M. Fischer, and E. Pickwell-MacPherson, "Effects of formalin fixing on the terahertz properties of biological tissues," J. Biomed. Opt. 14(6), 064017 (2009).
    • (2009) J. Biomed. Opt. , vol.14 , Issue.6 , pp. 064017
    • Sun, Y.1    Fischer, B.M.2    Pickwell-MacPherson, E.3
  • 58
    • 30744477479 scopus 로고    scopus 로고
    • Far-infrared signature of animal tissues characterized by terahertz time-domain spectroscopy
    • M. He, "Far-infrared signature of animal tissues characterized by terahertz time-domain spectroscopy," Opt. Commun. 259(1), 389-392 (2006).
    • (2006) Opt. Commun. , vol.259 , Issue.1 , pp. 389-392
    • He, M.1
  • 60
    • 0001194852 scopus 로고
    • Picosecond optoelectronic switching and gating in silicon
    • D. H. Auston, "Picosecond optoelectronic switching and gating in silicon," Appl. Phys. Lett. 26(3), 101-103 (1975).
    • (1975) Appl. Phys. Lett. , vol.26 , Issue.3 , pp. 101-103
    • Auston, D.H.1
  • 61
    • 0021475072 scopus 로고
    • Picosecond photoconducting hertzian dipoles
    • D. H. Auston, K. P. Cheung, and P. R. Smith, "Picosecond photoconducting Hertzian dipoles," Appl. Phys. Lett. 45(3), 284-286 (1984).
    • (1984) Appl. Phys. Lett. , vol.45 , Issue.3 , pp. 284-286
    • Auston, D.H.1    Cheung, K.P.2    Smith, P.R.3
  • 62
    • 21544452970 scopus 로고
    • Generation of femtosecond electromagnetic pulses from semiconductor surfaces
    • X. C. Zhang, B. B. Hu, J. T. Darrow, and D. H. Auston, "Generation of femtosecond electromagnetic pulses from semiconductor surfaces," Appl. Phys. Lett. 56(11), 1011-1013 (1990).
    • (1990) Appl. Phys. Lett. , vol.56 , Issue.11 , pp. 1011-1013
    • Zhang, X.C.1    Hu, B.B.2    Darrow, J.T.3    Auston, D.H.4
  • 64
    • 33644912652 scopus 로고
    • Dielectric spectra of some common solvents in the microwave region. Water and lower alcohols
    • J. Barthel, K. Bachhuber, et al., "Dielectric spectra of some common solvents in the microwave region. Water and lower alcohols," Chem. Phys. Lett. 165(4), 369-373 (1990).
    • (1990) Chem. Phys. Lett. , vol.165 , Issue.4 , pp. 369-373
    • Barthel, J.1    Bachhuber, K.2
  • 65
    • 77957333762 scopus 로고    scopus 로고
    • Comparative dielectric study of monohydric alcohols with terahertz time-domain spectroscopy
    • Y. Yomogida, Y. Sato, R. Nozaki, T. Mishina, and J. I. Nakahara, "Comparative dielectric study of monohydric alcohols with terahertz time-domain spectroscopy," J. Mol. Struct. 981(1-3), 173-178 (2010).
    • (2010) J. Mol. Struct. , vol.981 , Issue.1-3 , pp. 173-178
    • Yomogida, Y.1    Sato, Y.2    Nozaki, R.3    Mishina, T.4    Nakahara, J.I.5
  • 67
    • 0015604413 scopus 로고
    • Optical constants of water in the 200-nm to 200-microm wavelength region
    • G. M. Hale and M. R. Querry, "Optical constants of water in the 200-nm to 200-microm wavelength region," Appl. Opt. 12(3), 555-563 (1973).
    • (1973) Appl. Opt. , vol.12 , Issue.3 , pp. 555-563
    • Hale, G.M.1    Querry, M.R.2
  • 68
    • 0023170606 scopus 로고
    • The temperature variation of the near millimetre wavelength optical constants of water
    • J. B. Hasted, S. K. Husain, F. A. M. Frescura, and J. R. Birch, "The temperature variation of the near millimetre wavelength optical constants of water," Infrared Phys. 27(1), 11-15 (1987).
    • (1987) Infrared Phys. , vol.27 , Issue.1 , pp. 11-15
    • Hasted, J.B.1    Husain, S.K.2    Frescura, F.A.M.3    Birch, J.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.