Evaluation of CD4+ t cells in HIV patients presenting with malaria at the University of Ilorin Teaching Hospital Nigeria

EXCLI Journal

Volumn 9, Issue , 2010, Pages 58-66

  Agbede, Olajide O ^a   Ajiboye, Temitope O ^a   Kolawole, Olatunji M ^a,b   Babatunde, Samuel A ^a   Odeigha, Louis O ^a  

^a UNIVERSITY OF ILORIN   (Nigeria)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

CD4 count; CD4+ T lymphocytes; Flow cytometry; HIV AIDS; Immune system; Malaria

Indexed keywords

ARTICLE; BODY TEMPERATURE; CD4 LYMPHOCYTE COUNT; CLINICAL ARTICLE; FLOW CYTOMETRY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNE RESPONSE; MALARIA; NIGERIA; PARASITE IDENTIFICATION; PYREXIA IDIOPATHICA; TEACHING HOSPITAL;

EID: 80455137107     PISSN: None     EISSN: 16112156     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Bell C, Devarajan S, Gershach H. The longrun economic costs of AIDS: Theory and an application to South Africa. World Bank Working Paper 2003;No. 3152:23-45.
2. Cheesbrough M. District laboratory practice in tropical countries. 2nd ed. Cambridge: Cambridge Univ. Press, 2005, pp 244-51.
3. Clark IA, Budd AC, Alleva LM, Cowden WB. Pathogenesis of malaria and clinically similar conditions. Clin Microbiol Rev 2004;17:509-39.
4. Clark IA, Budd AC, Alleva LM, Cowden WB. Human malarial disease: a consequence of inflammatory cytokines. Malaria J 2006;5:85.
5. Davachi F, Kabongo L, Ngoie K. Decreased mortality from malaria in children with symptomatic HIV infection. International Conference on AIDS 1991;7:164.
6. Froebel K, Howard W, Schafer J. Activation by malaria antigens renders mononuclear cells susceptible to HIV infection and reactivates replication of endogenous HIV in cells from HIV- Sinfected adults. Parasite Immunol 2004;26:213-7.
7. Heimlich H. Malariotherapy: An affordable and accessible treatment for HIV/AIDS. Paper presented at the Pan Africa AIDS conference. (2002).
8. Hoffman IF, Jere CS, Taylor TE, Munthali P, Dyer JR, Wirima JJ, Rogerson SJ, Kumwenda N, Eron JJ, Fiscus SA, Chakraborty H, Taha TE, Cohen MS, Molyneux ME. The effect of Plasmodium falciparum malaria on HIV-1 RNA blood plasma concentration. AIDS 1999;13:87-94.
9. Hviid L, Theander T, Abu Zeid Y, Abdulhadi N, Jakobsen P, Saeed B, Jepsen S, Bayoumi RA, Jensen JB. Loss of cellular immune reactivity during acute Plasmodium falciparum malaria. FEMS Microbiol Immunol 1991;3:219-27.
10. Imade GE, Badung B, Pam S, Agbaji O, Egah D, Sagay A. Comparison of a new, affordable flow cytometric method and the manual magnetic bead techique for CD4 Tlymphocyte counting in a Northern Nigerian setting. Clin Diagn Lab Immunol 2005;12:224-7.
11. Karunaweera N, Wijesekera S, Wanasekera D, Mendis K, Carter R. The paroxysm of Plasmodium vivax malaria. Trends Parasitol 2003;19:188-93.
12. Lyke KE, Burges R, Cissoko Y, Sangare L, Dao M, Diarra I, Kone A, Harley R, Plowe CV, Doumbo OK, Sztein MB. Serum levels of the proinflammatory cytokines interleukin- 1 Beta (IL-1β), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12 (p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls. Infect Immun 2004;72:5630-7.
13. Mermin J, Lule J, Ekwaru J. Association between malaria and CD4 cell count decline among persons with HIV. J Acquir Immune Defic Syndr 2006;41:129-30.
14. Moore K, O'Garra A, De Waal Malefyr R, Vieira P, Mosmann T. Interleukin-10. Annu Rev Immunol 1993;11:165-90.
15. Ozaki K, Leonard W. Cytokine and cytokine receptor pleiotropy and redundancy. J Biol Chem 2002:277:29355-8.
16. Petrovsky N, Harrison L. The chronobiology of human cytokine production. Int Rev Immunol 1998;16:635-49.
17. Pickrell J. HIV and AIDS. http://www.newscientist.com (2005).
18. UNICEF. Malaria and HIV. Malaria Technical Note 6 (2003).
19. University of Ilorin Teaching Hospital. Annual report 2000: 5.
20. Whitworth J, Morgan D, Quigley M, Smith A, Mayanja B, Eotu H, Omoding N, Okongo M, Malamba S, Ojwiya A. Effect of HIV-1and increasing immunosuppression on malaria parasitaemia and clinical episodes in adults in rural Uganda: a cohort study. Lancet 2000;356:1051-6.
21. Whitworth J, Hewitt K. Effect of malaria on HIV-1 progression and transmission. Lancet 2005;365:196-7.
22. WHO, World Health Organization. Malaria. http://www.who.int.com (2006).