Drop in platelet counts in extremely preterm neonates and its association with clinical outcomes

Journal of Pediatric Hematology/Oncology

Volumn 33, Issue 8, 2011, Pages 580-584

  Rastogi, Shantanu ^a   Olmez, Inan ^b   Bhutada, Alok ^c   Rastogi, Deepa ^d  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c MAIMONIDES MEDICAL CENTER   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

clinical outcomes; drop in platelet counts; length of stay; morbidity; mortality; prematurity; thrombocytopenia

Indexed keywords

ARTICLE; BIRTH WEIGHT; BLEEDING; CONTROLLED STUDY; DISEASE ASSOCIATION; DROP IN PLATELET COUNT; EXTREMELY PRETERM NEONATE; FEMALE; GESTATIONAL AGE; GRAM POSITIVE INFECTION; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MYCOSIS; NECROTIZING ENTEROCOLITIS; NEONATAL THROMBOCYTOPENIA; NEWBORN; NEWBORN MORBIDITY; NEWBORN MORTALITY; PREDICTION; PREMATURITY; PREVALENCE; PRIORITY JOURNAL; RETROLENTAL FIBROPLASIA; SURVIVAL TIME; THROMBOCYTE COUNT; THROMBOCYTOPATHY;

ENTEROCOLITIS, NECROTIZING; FEMALE; GESTATIONAL AGE; GRAM-NEGATIVE BACTERIAL INFECTIONS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFECTION; LENGTH OF STAY; MALE; MORBIDITY; MYCOSES; PLATELET COUNT; PREDICTIVE VALUE OF TESTS; PREVALENCE; RETROSPECTIVE STUDIES; THROMBOCYTOPENIA;

EID: 80455130019     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e31821e5f44     Document Type: Article

References (16)

1. Mehta P, Vasa R, Neumann L, et al. Thrombocytopenia in the high-risk infant. J Pediatr. 1980;97:791-794.
2. Roberts I, Stanworth S, Murray NA. Thrombocytopenia in the neonate. Blood Rev. 2008;22:173-186.
3. Chakravorty S, Murray N, Roberts I. Neonatal thrombocytopenia. Early Hum Dev. 2005;81:35-41.
4. Bussel JB, Sola-Visner M. Current approaches to the evaluation and management of the fetus and neonates with immune thrombocytopenia. Semin Perinatol. 2009;33:35-42.
5. Christensen RD, Henry E, Wiedmeier SE, et al. Thrombocytopenia among extremely low birth weight neonates: Data from a multihospital healthcare system. J Perinatol. 2006;26:348-353.
6. Bonifacio L, Petrova A, Nanjundaswamy S, et al. Thrombocytopenia related neonatal outcome in preterm infants. Indian J Pediatr. 2007;74:269-274.
7. Rastogi S, Olmez I, Bhutada A, et al. NCI classification of thrombocytopenia in extremely preterm neonates and its association with mortality and morbidity. J Perinat. Med. 2011;39:65-69.
8. Oguzulgen IK, Ozis T, Gursel G. Is the fall in platelet count associated with intensive care unit acquired pneumonia? Swiss Med Wkly. 2004;134:430-434.
9. Warris A, Semmekrot BA, Voss A. Candidal and bacterial bloodstream infections in preterm neonates: A case-control study. Med Mycol. 2001;39:75-79.
10. Baer VL, Lambert DK, Henry E, et al. Severe Thrombocytopenia in the NICU. Pediatrics 2009;124:e1095-e1100.
11. Castle V, Andrew M, Kelton J, et al. Frequency and mechanism of neonatal thrombocytopenia. J Pediatr. 1986;108:749-755.
12. François B, Trimoreau F, Vignon P, et al. Thrombocytopenia in the sepsis syndrome: Role of hemophagocytosis and macrophage colony-stimulating factor. Am J Med. 1997;103: 114-120.
13. Yeaman MR. The role of platelets in antimicrobial host defense. Clin Infect Dis. 1997;25:951-968.
14. Bhat MA, Bhat JI, Kawoosa MS, et al. Organism-specific platelet response and factors affecting survival in thrombocytopenic VLBW babies with sepsis. J Perinatol. 2009;29: 702-708.
15. Guida JD, Kunig AM, Leef KH, et al. Platelet count and sepsis in VLBW neonates: Is there an organism specific response? Pediatrics. 2003;111:1411-1415.
16. Manzoni P, Mostert M, Galletto P, et al. Is thrombocytopenia suggestive of organism-specific response in neonatal sepsis? Pediatr Int. 2009;51:206-210.