Medicinal chemistry of novel anti-diabetic drugs

Open Medicinal Chemistry Journal

Volumn 5, Issue SPEC. ISSUE 2, 2011, Pages 68-69

  Adeghate, Ernest ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

[No Author keywords available]

Indexed keywords

ACARBOSE; ALPHA GLUCOSIDASE INHIBITOR; AMYLIN; BIGUANIDE DERIVATIVE; GLITAZONE DERIVATIVE; GLUCOSE; HERBACEOUS AGENT; INSULIN; MEGLITINIDE; MIGLITOL; ORAL ANTIDIABETIC AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; SULFONYLUREA DERIVATIVE; VILDAGLIPTIN;

DIABETES MELLITUS; DRUG MECHANISM; DRUG PROTEIN BINDING; EDITORIAL; FRUIT JUICE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; MOMORDICA CHARANTIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 80455125820     PISSN: None     EISSN: 18741045     Source Type: Journal    
DOI: 10.2174/1874104501105010068     Document Type: Editorial

References (14)

1. Amos, A.F.; McCarty, D.J.; Zimmet, P. The rising global burden of diabetes and its complications: estimates and projections to the year 2010. Diabet. Med., 1997, 14(Suppl. 5), S1-85.
2. Adeghate, E.; Schattner, P.; Dunn, E. An Update on the Etiology and Epidemiology of Diabetes Mellitus. Ann. N.Y. Acad. Sci., 2006, 1084, 1-29.
3. Schweiger, B.; Klingensmith, G.; Snell-Bergeon, J.K. Physical activity in adolescent females with type 1 diabetes. Int. J. Pediatr., 2010, 328318.
4. Shenoy, S.; Arora, E.; Jaspal, S. Effects of progressive resistance training and aerobic exercise on type 2 diabetics in Indian population. Int. J. Diabetes Metab., 2009, 17, 27-30.
5. S. Diabetes mellitus and its treatment. Int. J. Diabetes Metab., 2005, 13,111-134.
6. Sum, C.F.; Webster, J.M.; Johnson, A.B.; Catalano, C.; Cooper, B.G.; Taylor, R. The effect of intravenous metformin on glucose metabolism during hyperglycaemia in type 2 diabetes. Diabet. Metab., 1992, 9, 61-65.
7. Hundal, H.S.; Ramlal, T.; Reyes, R.; Leiter, L.A.; Klip, A. Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells. Endocrinology, 1992, 131, 1165-1173.
8. Fuhlendorff, J.; Rorsman, P.; Kofod, H.; Brand, C.L.; Rolin, B.; MacKay, P.; Shymko, R.; Carr, R.D. Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct process. Diabetes, 1998, 47, 345-451.
9. Reabasa-Lhoret, R.; Chiasson, J-L. Potential of alphaglucosidase inhibitors in elderly patients with diabetes mellitus and impaired glucose tolerance. Drug Aging, 1998, 13, 131-143.
10. Stote, R.; Marbury, T.; Shi, L.; Miller, M.; Strange, P. Comparison pharmacokinetics of two concentrations (0.7% and 1.0%) of Nasulin, an ultra-rapid-acting intranasal insulin formulation. J. Diabetes Sci. Technol., 2010, 4, 603-609.
11. Bnouham, M.; Ziyyat, A.; Mekhfi, H.; Tahri, A.; Legssyer, A. Medicinal plants with potential antidiabetic activity - A review of ten years of herbal medicine research (1990-2000). Int. J. Diabetes Metab., 2006, 14, 1-25.
12. Ahmed, I.; Adeghate, E.; Sharma, A.K.; Pallot, D.J.; Singh, J. Effects of Momordica charantia fruit juice on islet morphology in the pancreas of the streptozotocin-diabetic rat. Diabetes Res. Clin. Pract., 1998, 40, 145-151.
13. Ahmed, I.; Adeghate, E.; Cummings, E.; Sharma, A.K.; Singh, J. Beneficial effects and mechanism of action of Momordica charantia fruit juice in the treatment of streptozotocin-induced diabetes mellitus in rat. Mol. Cell. Biochem., 2004, 261, 63-70.
14. Cummings, E.; Hundal, H.S.; Wackerhage, H.; Hope, M.; Belle, M.; Adeghate, E.; Singh, J. Mormodica charantia fruit juice stimulates glucose and amino acid uptake in L6 myotubules. Mol. Cell. Biochem., 2004, 261, 99-104.